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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_18 | Pages 16 - 16
1 Dec 2023
Saghir R Watson K Martin A Cohen A Newman J Rajput V
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Introduction

Knee arthroscopy can be used for ligamentous repair, reconstruction and to reduce burden of infection. Understanding and feeling confident with knee arthroscopy is therefore a highly important skillset for the orthopaedic surgeon. However, with limited training or experience, furthered by reduced practical education due to COVID-19, this skill can be under-developed amongst trainee surgeons.

Methods

At a single institution, ten junior doctors (FY1 to CT2), were recruited as a part of a five, two-hour session, training programme utilising the Simbionix® ARTHRO Mentor knee arthroscopy simulator, supplemented alongside educational guidance with a consultant orthopaedic knee surgeon. All students had minimal to no levels of prior arthroscopic experience. Exercises completed included maintaining steadiness, image centring and orientation, probe triangulation, arthroscopic knee examination, removal of loose bodies and meniscectomy. Pre and post experience questionnaires and quantitative repeat analysis on simulation exercises were undertaken to identify levels of improvement.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 58 - 58
7 Aug 2023
Saghir R Watson K Martin A Cohen A Newman J Rajput V
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Abstract

Introduction

Knee arthroscopy can be used for ligamentous repair, reconstruction and to reduce burden of infection. Understanding and feeling confident with knee arthroscopy is therefore a highly important skillset for the orthopaedic surgeon. However, with limited training or experience, furthered by reduced practical education due to COVID-19, this skill can be under-developed amongst trainee surgeons.

Methods

At a single institution, ten junior doctors (FY1 to CT2), were recruited as a part of a five, two-hour session, training programme utilising the Simbionix® ARTHRO Mentor knee arthroscopy simulator, supplemented alongside educational guidance with a consultant orthopaedic knee surgeon. All students had minimal to no levels of prior arthroscopic experience. Exercises completed included maintaining steadiness, image centering and orientation, probe triangulation, arthroscopic knee examination, removal of loose bodies, and meniscectomy. Pre and post-experience questionnaires and quantitative repeat analysis on simulation exercises were undertaken to identify levels of improvement.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_9 | Pages 14 - 14
17 Apr 2023
Bartolo M Newman S Dandridge O Provaggi E Accardi M Dini D Amis A
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No proven long-term joint-preserving treatment options exist for patients with irreparable meniscal damage. This study aimed to assess gait kinematics and contact pressures of novel fibre-matrix reinforced polyvinyl alcohol-polyethylene glycol (PVA-PEG) hydrogel meniscus implanted ovine stifle joints against intact stifles in a gait simulator.

The gait simulator controlled femoral flexion-extension and applied a 980N axial contact force to the distal end of the tibia, whose movement was guided by the joint natural ligaments (Bartolo; ORS 2021;p1657- LB). Five right stifle joints from sheep aged >2 years were implanted with a PVA-PEG total medial meniscus replacement, fixed to the tibia via transosseous tunnels and interference screws. Implanted stifle joint contact pressures and kinematics in the simulator were recorded and compared to the intact group. Contact pressures on the medial and lateral condyles were measured at 55° flexion using Fujifilm Prescale Low Pressure film inserted under the menisci. 3D kinematics were measured across two 30 second captures using the Optotrak Certus motion-tracking system (Northern Digital Inc.).

Medial peak pressures were not significantly different between the implanted and intact groups (p>0.4), while lateral peak pressures were significantly higher in the implanted group (p<0.01). Implanted stifle joint kinematics in the simulator did not differ significantly from the intact baseline (p>0.01), except for in distraction-compression (p<0.01).

Our findings show that the fibre-matrix reinforced PVA-PEG hydrogel meniscal replacement restored the medial peak contact pressures. Similar to published literature (Fischenich; ABE 2018;46(11):1–12), the lateral peak pressures in the implanted group were higher than the intact. Joint kinematics were similar across groups, with slightly increased internal-external rotation in the implanted group. These findings highlight the effectiveness of the proposed approach and motivate future work on the development of a total meniscal replacement.


Bone & Joint Open
Vol. 3, Issue 8 | Pages 648 - 655
1 Aug 2022
Yeung CM Bhashyam AR Groot OQ Merchan N Newman ET Raskin KA Lozano-Calderón SA

Aims

Due to their radiolucency and favourable mechanical properties, carbon fibre nails may be a preferable alternative to titanium nails for oncology patients. We aim to compare the surgical characteristics and short-term results of patients who underwent intramedullary fixation with either a titanium or carbon fibre nail for pathological long-bone fracture.

Methods

This single tertiary-institutional, retrospectively matched case-control study included 72 patients who underwent prophylactic or therapeutic fixation for pathological fracture of the humerus, femur, or tibia with either a titanium (control group, n = 36) or carbon fibre (case group, n = 36) intramedullary nail between 2016 to 2020. Patients were excluded if intramedullary fixation was combined with any other surgical procedure/fixation method. Outcomes included operating time, blood loss, fluoroscopic time, and complications. Fisher’s exact test and Mann-Whitney U test were used for categorical and continuous outcomes, respectively.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 23 - 23
1 Jul 2022
Frame M Hauck O Newman M
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Abstract

Introduction

Tibial tubercle osteotomy (TTO) is a complex surgical procedure with a significant risk of complications, which include nonunion and tibial fracture. To determine whether an additional suture tape augmentation can provide better biomechanical stability compared with standard screw fixation.

Methods

Five matched pairs of human cadaveric knees were divided into 2 groups: the first group underwent standard TTO fixation with 2 parallel screws. The second group underwent a novel fixation technique, in which a nonabsorbable suture tape (FiberTape) in a figure-of-8 construct was added to the standard screw fixation. Tubercular fragment migration of >50% of the initial distalization length was defined as clinical failure Tubercular fragment displacement during cyclic loading and pull-to-failure force were recorded and compared between the 2 groups.


The Bone & Joint Journal
Vol. 103-B, Issue 6 | Pages 1173 - 1173
1 Jun 2021
Alsousou J Oragui E Martin A Strickland L Newman S Kendrick B Taylor A Glyn-Jones S


The Bone & Joint Journal
Vol. 103-B, Issue 4 | Pages 644 - 649
1 Apr 2021
Alsousou J Oragu E Martin A Strickland L Newman S Kendrick B Taylor A Glyn-Jones S

Aims

The aim of this prospective cohort study was to evaluate the early migration of the TriFit cementless proximally coated tapered femoral stem using radiostereometric analysis (RSA).

Methods

A total of 21 patients (eight men and 13 women) undergoing primary total hip arthroplasty (THA) for osteoarthritis of the hip were recruited in this study and followed up for two years. Two patients were lost to follow-up. All patients received a TriFit stem and Trinity Cup with a vitamin E-infused highly cross-linked ultra-high molecular weight polyethylene liner. Radiographs for RSA were taken postoperatively and then at three, 12, and 24 months. Oxford Hip Score (OHS), EuroQol five-dimension questionnaire (EQ-5D), and adverse events were reported.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_5 | Pages 1 - 1
1 Jul 2020
Fernquest S Palmer A Gimpel M Birchall R Broomfield J Wedatilake T Dijkstra H Lloyd T Pereira C Newman S Carr A Glyn-Jones S
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Background

Cam morphology develops during adolescence and predisposes individuals to future hip pain and osteoarthritis. An improved understanding of cam development is required to determine whether the process is modifiable.

Hypothesis/Purpose

The aim of this study was to characterise the risk factors, timing, and pathogenesis of cam formation.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 83 - 83
1 Feb 2020
Wolff D Newman J Shah N Morrissey P Conway C Gold R Tretiakov M Sedaghatpour D Pivec R Naziri Q Illical E
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Purpose

Infections in orthopaedic surgery are costly, debilitating complications. The search for new treatments and prevention strategies has led to the use of antibiotic-filled calcium sulfate (CaS) as a bone void filler that is both safe and effective. The purpose of this study was to examine the available data on the efficacy of this technology.

Methods

A literature search was performed for studies that evaluated the use of antibiotic-loaded CaS cement in orthopaedics published between inception of the databases to 2017. Selected studies included randomized controlled trials (RCTs) and observational studies published in the English language that met the following criteria: 1) patients underwent an orthopaedic procedure; 2) CaS cement with an antibiotic was used; and 3) at least one of our outcomes were mentioned. Outcomes included resolution of infection, complications related to treatment, subsequent surgeries, overall infection rate, fracture union rate, clinical outcomes, and wound complications. A total of 17 studies were included.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 86 - 86
1 Feb 2020
Khondakar N Shah N Murtaugh T Gold R Aylyarov A Pascal S Harb M Newman J Schwartz J Maheshwari A
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Summary

A meta-analysis was performed to compare rate of SSI after application of chlorhexidine vs. iodine in total joint arthroplasty. Chlorhexidine had significantly lower odds of SSI.

Introduction

Surgical site infections (SSI) are a significant source of morbidity and mortality. The optimal preoperative skin preparation in lower extremity total joint arthroplasty (TJA) remains debatable between chlorhexidine and iodine-containing solutions. This meta-analysis sought compare SSI rates between chlorhexidine cloth application the night before surgery plus povidone-iodine-alcohol (povidone-iodine) solution at surgery or only povidone-iodine at surgery.


The Bone & Joint Journal
Vol. 100-B, Issue 7 | Pages 875 - 881
1 Jul 2018
Newman JM Khlopas A Sodhi N Curtis GL Sultan AA George J Higuera CA Mont MA

Aims

This study compared multiple sclerosis (MS) patients who underwent primary total hip arthroplasty (THA) with a matched cohort. Specifically, we evaluated: 1) implant survivorship; 2) functional outcomes (modified Harris Hip Scores (mHHS), Hip Disability and Osteoarthritis Outcome Score, Joint Replacement (HOOS JR), and modified Multiple Sclerosis Impact Scale (mMSIS) scores (with the MS cohort also evaluated based on the disease phenotype)); 3) physical therapy duration and return to function; 4) radiographic outcomes; and 5) complications.

Patients and Methods

We reviewed our institution’s database to identify MS patients who underwent THA between January 2008 and June 2016. A total of 34 MS patients (41 hips) were matched in a 1:2 ratio to a cohort of THA patients who did not have MS, based on age, body mass index (BMI), and Charlson/Deyo score. Patient records were reviewed for complications, and their functional outcomes and radiographs were reviewed at their most recent follow-up.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 58 - 58
1 Jan 2018
Newman J Khlopas A Sodhi N Curtis G Sultan A Higuera C Mont M
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Patients who have multiple sclerosis (MS) may be at increased risk of developing complications after total hip arthroplasty (THA). The purpose of this study was to compare: 1) implant survivorship; 2) functional outcomes; 3) complication rates; and 4) radiographic findings after THA between MS patients and a matched cohort.

A single institutional database was reviewed for patients who had a diagnosis of MS and underwent a THA. Thirty-four patients (41 hips) were matched to a 2:1 cohort who did not have MS using based on age, sex, body mass index (BMI), and Charlson/Deyo scores. This resulted in a matching cohort of 80 patients (82 hips). The available medical records were reviewed. Functional outcomes and complications were assessed. Postoperative radiographs were evaluated.

The matching cohort had higher all-cause survivorship at 4-years postoperatively (99 vs. 93%). There were 3 revisions in the MS cohort and 0 revisions in the matching cohort. The MS cohort had lower mHHS scores (66 vs.74 points, p<0.001), lower HOOS JR scores (79 vs. 88 points, p<0.01), required more physical therapy (5 vs. 3 weeks, p<0.01), and took longer to return to their baseline functional level (7 vs. 5 weeks, p<0.05). MS patients had higher rate of complications (6 vs. 1, p<0.05). Excluding revision cases, there was no additional radiographic evidence of progressive radiolucency, loosening, or subsidence.

We found that MS patients had lower implant survivorship, lower functional outcome scores, and increased complication rates. These findings may help orthopaedists to have a better knowledge of how MS patients do after THA.


Bone & Joint Research
Vol. 6, Issue 8 | Pages 522 - 529
1 Aug 2017
Ali AM Newman SDS Hooper PA Davies CM Cobb JP

Objectives

Unicompartmental knee arthroplasty (UKA) is a demanding procedure, with tibial component subsidence or pain from high tibial strain being potential causes of revision. The optimal position in terms of load transfer has not been documented for lateral UKA. Our aim was to determine the effect of tibial component position on proximal tibial strain.

Methods

A total of 16 composite tibias were implanted with an Oxford Domed Lateral Partial Knee implant using cutting guides to define tibial slope and resection depth. Four implant positions were assessed: standard (5° posterior slope); 10° posterior slope; 5° reverse tibial slope; and 4 mm increased tibial resection. Using an electrodynamic axial-torsional materials testing machine (Instron 5565), a compressive load of 1.5 kN was applied at 60 N/s on a meniscal bearing via a matching femoral component. Tibial strain beneath the implant was measured using a calibrated Digital Image Correlation system.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 22 - 22
1 Feb 2017
Huixiang W Newman S Jones G Sugand K Cobb J Auvinet E
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Introduction

Because of the low cost and easy access, surgical video has become a popular method of acquiring surgical skills outside operating rooms without disrupting normal surgical flow. However, currently existing video systems all use a single point of view (POV). Some complex orthopedic procedures, such as joint replacement, require a level of accuracy in several dimensions. So single and fixed POV video may not be enough to provide all the necessary information for educational and training purposes. The aim of our project was to develop a novel multiple POV video system and evaluate its efficacy as an aid for learning joint replacement procedure compared with traditional method.

Materials and Methods

Based on the videos of a hip resurfacing procedure performed by an expert orthopedic surgeon captured by 8 cameras fixed all around the operating table, we developed a novel multiple POV video system which enables users to autonomously switch between optimal viewpoints (Figure 1). 30 student doctors (undergraduate years 3–5 and naive to hip resurfacing procedure) were recruited and randomly allocated to 2 groups: experiment group and control group, and were assigned to learn the procedure using multiple or single POV video systems respectively. Before learning they were first asked to complete a multiple choicetest designed using a modified Delphi technique with the advice and feedback sought from 4 experienced orthopedic surgeons to test the participants' baseline knowledge of hip resurfacing procedure. After video learning, they were asked to answer the test again to verify their gained information and comprehension of the procedure, followed by a 5-point Likert-scale questionnaire to demonstrate their self-perception of confidence and satisfaction with the learning experience. The scores in the 2 tests and in the Likert-scale questionnaire were compared between 2 groups using Independent-Samples t-test (for normally distributed data) or Mann-Whitney U test (for non-normally distributed data). Statistical significance was set as p<0.05.


The Bone & Joint Journal
Vol. 98-B, Issue 7 | Pages 884 - 891
1 Jul 2016
Elliott DS Newman KJH Forward DP Hahn DM Ollivere B Kojima K Handley R Rossiter ND Wixted JJ Smith RM Moran CG

This article presents a unified clinical theory that links established facts about the physiology of bone and homeostasis, with those involved in the healing of fractures and the development of nonunion. The key to this theory is the concept that the tissue that forms in and around a fracture should be considered a specific functional entity. This ‘bone-healing unit’ produces a physiological response to its biological and mechanical environment, which leads to the normal healing of bone. This tissue responds to mechanical forces and functions according to Wolff’s law, Perren’s strain theory and Frost’s concept of the “mechanostat”. In response to the local mechanical environment, the bone-healing unit normally changes with time, producing different tissues that can tolerate various levels of strain. The normal result is the formation of bone that bridges the fracture – healing by callus. Nonunion occurs when the bone-healing unit fails either due to mechanical or biological problems or a combination of both. In clinical practice, the majority of nonunions are due to mechanical problems with instability, resulting in too much strain at the fracture site. In most nonunions, there is an intact bone-healing unit. We suggest that this maintains its biological potential to heal, but fails to function due to the mechanical conditions. The theory predicts the healing pattern of multifragmentary fractures and the observed morphological characteristics of different nonunions. It suggests that the majority of nonunions will heal if the correct mechanical environment is produced by surgery, without the need for biological adjuncts such as autologous bone graft.

Cite this article: Bone Joint J 2016;98-B:884–91.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 30 - 30
1 May 2016
Newman S Clarke S Harris S Cobb J
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Introduction

Patient Specific Instrumentation (PSI) has the potential to allow surgeons to perform procedures more accurately, at lower cost and faster than conventional instrumentation. However, studies using PSI have failed to convincingly demonstrate any of these benefits clinically. The influence of guide design on the accuracy of placement of PSI has received no attention within the literature.

Our experience has suggested that surgeons gain greater benefit from PSI when undertaking procedures they are less familiar with. Lateral unicompartmental knee replacement (UKR) is relatively infrequently performed and may be an example of an operation for which PSI would be of benefit. We aimed to investigate the impact on accuracy of PSI with respect to the area of contact, the nature of the contact (smooth or studded guide surfaces) and the effect of increasing the number of contact points in different planes.

Method

A standard anatomy tibial Sawbone was selected for use in the study and a computed tomography scan obtained to facilitate the production of PSI. Nylon PSI guides were printed on the basis of a lateral UKR plan devised by an orthopaedic surgeon. A control PSI guide with similar dimensions to the cutting block of the Oxford Phase 3 UKR tibial guide was produced, contoured to the anterior tibial surface with multiple studs on the tibial contact surface. Variants of this guide were designed to assess the impact of design features on accuracy. These were: a studded guide with a 40% reduction in tibial contact area, a non-studded version of the control guide, the control guide with a shim to provide articular contact, a guide with an extension to allow distal referencing at the ankle and a guide with a distal extension and an articular shim. All guides were designed with an appendage that facilitated direct attachment to a navigation machine (figure 1). 36 volunteers were asked to place each guide on the tibia with reference to a 3D model of the operative plan. The order of placement was varied using a counterbalanced latin square design to limit the impact of the learning effect. The navigation machine recorded deviations from the plan in respect of proximal-distal and medial-lateral translations as well as rotation around all three axes. Statistical analysis was performed on the compound translational and rotational errors for each guide using ANOVA with Bonferroni correction with statistical significance at p<0.05.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 32 - 32
1 Jan 2016
Carroll K Newman J Holmes A Della Valle AG Cross MB
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Introduction

Stiffness after total knee arthroplasty is a common occurrence. Despite its prevalence, little is known as to which patients are at risk for poor range of motion after total knee arthroplasty. The purpose of this study was to determine the risk factors for manipulation under anesthesia (MUA) after total knee arthroplasty (TKA).

Methods

Using a single institution registry, 160 patients who underwent a manipulation under anesthesia after total knee arthroplasty between 2007 and 2013 were retrospectively evaluated. Each patient was 1:1 matched by age, gender and laterality to a control group of 160 patients who did not require MUA after TKA. Risk factors for MUA were assessed, and included medical co-morbidities, BMI, prior operations, and preoperative range of motion.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_8 | Pages 6 - 6
1 Feb 2013
Granville-Chapman J Nawaz S Trompeter A Newman K Elliott D
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Intramedullary nailing of tibial fractures is commonplace and freehand techniques are increasingly popular. The standard freehand method has the knee of the injured leg flexed over a radio-lucent bolster. This requires the imaging C-arm to swing from antero-posterior to lateral position several times. Furthermore, guide wire placement; reaming and nail insertion are all performed well above most surgeons' shoulder height. If instead the leg is hung over the edge of the table, the assistant must crouch and hold the leg until the nail is passed beyond the fracture.

We describe a method of nailing which is easier both for the surgeons and the (often inexperienced) radiographer and present a series of 87 consecutive cases managed with this technique.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 157 - 157
1 Jan 2013
Nawaz S Keightley A Elliott D Newman K Khaleel A
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Currently the debate continues in definitive fixation method for complex tibial plateau fractures. The aim of surgical management remains prevention of further damage to the articular cartilage, whilst avoiding iatrogenic risks - Low Risk Surgery (LRS). The purpose of this study was to determine the functional impact, clinical radiological outcome following tibial plateau fractures treated with either external fixation or internal fixation.

124 Schatzker IV-VI tibial plateau fractures were reviewed following surgical fixation. Fractures analysed included 24 type IV, 20 type V and 80 type VI tibial plateau fractures. The majority of Schatzker IV fractures were treated with internal fixation, but 67 of 80 Schatzker VI fractures were treated with the Ilizarov method. The average IOWA knee score, was 86 (16 to 100) and the average range of motion was 133 degrees (60 to 150). There were no differences between the circular fixator group and the internal fixation group in terms of range of motion or IOWA scores. There were comparable functional outcomes and complication rates between both groups.

In summary patients with high energy tibial plateau fracture treated with internal or external fixation, have a good chance of achieving satisfactory long term knee function.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 537 - 537
1 Sep 2012
Mohammed R Farook M Newman K
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We reviewed our results and complications of using a pre-bent 1.6mm Kirschner wire (K-wire) for extra-articular metacarpal fractures. The surgical procedure was indicated for angulation at the fracture site in a true lateral radiograph of at least 30 degrees and/or in the presence of a rotatory deformity.

A single K-wire is pre-bent in a lazy-S fashion with a sharp bend at approximately 5 millimetres and a longer smooth curve bent in the opposite direction. An initial entry point is made at the base of the metacarpal using a 2.5mm drill by hand. The K-wire is inserted blunt end first in an antegrade manner and the fracture reduced as the wire is passed across the fracture site. With the wire acting as three-point fixation, early mobilisation is commenced at the metacarpo-phalangeal joint in a Futuro hand splint.

The wire is usually removed with pliers post-operatively at four weeks in the fracture clinic.

We studied internal fixation of 18 little finger and 2 ring finger metacarpal fractures from November 2007 to August 2009. The average age of the cohort was 25 years with 3 women and 17 men. The predominant mechanism was a punch injury with 5 diaphyseal and 15 metacarpal neck fractures. The time to surgical intervention was a mean 13 days (range 4 to 28 days). All fractures proceeded to bony union. The wire was extracted at an average of 4.4 weeks (range three to six weeks). At an average follow up of 8 weeks, one fracture had to be revised for failed fixation and three superficial wound infections needed antibiotic treatment.

With this simple and minimally invasive technique performed as day-case surgery, all patients were able to start mobilisation immediately.

The general outcome was good hand function with few complications.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 29 - 29
1 Jul 2012
Parwez T Hassaballa M Artz N Robinson J Murray J Porteous A Newman J
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Purpose

The aim of this study was to compare the short-term and mid-term outcome of lateral UKRs using a single prosthesis, the AMC Uniglide knee implant.

Methods

Between 2003 and 2010, seventy lateral unicompartmental knee replacements (mean patient age 63.6±12.7 years) were performed at our unit for isolated lateral compartmental disease. Range of knee motion and functional outcome measures including the American Knee Society (AKSS), Oxford (OKS) and WOMAC scores were recorded from 19 knees at five years' post-operatively and compared to 35 knees at two-years and 53 knees at one-year post-op.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 42 - 42
1 Jul 2012
Hassaballa M Murray J Robinson J Porteous A Newman J
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Introduction

Kneeling ability is better in unicompartmental than total knee arthroplasty. There is also an impression that mobile bearing knees achieve better functional outcome than their fixed bearing cousins in unicompartmental and to a lesser extent total joint arthroplasty. In the UK, the market leading unicompartmental replacement is mobile bearing.

Aim

To analyse kneeling ability after total and unicompartmental knee replacement using mobile and fixed bearing inserts.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 45 - 45
1 Mar 2012
Newman J
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Introduction

Trochlear dysplasia (TD) is still poorly recognised, generally considered uncommon and to present purely as persistent patella dislocation.

Diagnosis

87 patients diagnosed as having TD by a true lateral X-ray, MRI scan or at surgery were sent a questionnaire about their initial symptoms. 60% had suffered adolescent anterior knee pain. Lack of trust, wobbling, stair problems, giving way and catching were also common symptoms. Only 66% had ever suffered a dislocation, their troubles had started at 12 years of age. Most had undergone unsuccessful realignment procedures and many had developed premature lateral patello-femoral arthritis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 111 - 111
1 Mar 2012
Pydisetty R Newman J
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Between 1989 and 1992 102 knees adjudged suitable for Unicompartmental replacement (UKR) were randomised to receive either a St Georg Sled UKR or a Kinematic modular total knee replacement (TKR). The early results demonstrated that the UKR group had less complications, and more rapid rehabilitation. At 5 years there were equal failures but the UKR group had more excellent results and a greater range of movement.

Despite this doubt persisted about whether these advantages would be maintained these cases have been followed regularly by a research nurse at 8, 10, 12 years. We now report the final outcome at 15 years. 43 patients (45 knees) have died with all their knees intact. Throughout the review period the Bristol Knee Scores (BKS) of the UKR group have been better and at 15 years 77% and 53% of the surviving UKRs and TKRs achieve an excellent score. 6 TKRs and 4 UKRs have failed during the 15 years of the review.

Conclusion

The better early results with UKR are maintained at 15 years with no greater failure rate. The median BKS scores of the UKR group was 91.1 at five years and 92 at 15 years suggesting little functional deterioration in either the prosthesis or remainder of the joint. These results would seem to justify the increased use of UKR.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 87 - 87
1 Feb 2012
Patel R Stygall J Harrington J Newman S Haddad F
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We aimed to measure cerebral microemboli load during total hip [THA] and knee arthroplasty (TKA) using transcranial Doppler ultrasound (TCD) and to investigate whether cerebral embolic load influences neuropsychiatric outcome. The timing of the microemboli was also related to certain surgical activities to determine if a specific relationship exists and the presence of a patent foramen ovale was investigated.

Patients undergoing primary THA and TKA underwent a battery of ten neuropsychiatric tests pre-operatively and at 6 weeks and 6 months post-operatively. Microembolic load was recorded using TCD onto VHS tape for subsequent analysis. Patent foramen ovale detection was performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre. The timing of specific surgical steps was recorded for each operation and embolic load calculated for that period. All patients were assessed for quality of life and orthopaedic outcome measures.

Results

45 THA patients and 50 TKA patients were studied. Cerebral microembolisation occurred in 35% of all patients (10 THA patients and 19 TKA patients). Mean microembolic load was 2.8 per patient for THA and 3.76 per patient for TKA patients. PFO was detected in 29 patients overall. Insertion of the femoral component and deflation of the tourniquet were associated with a larger microembolic loads. Neuropsychiatric outcome was not affected by the low embolic loads. Quality of life and Orthopaedic outcome at 6 months was good.

Conclusion

Cerebral microembolisation occurs in a significant proportion of patients during total hip and knee arthroplasty. The presence of a patent foramen ovale does not appear to influence the incidence of microembolisation or load. Specific surgical activities are associated with generating greater embolic loads and methods of avoiding these emboli such as venting the femur may minimise complications and optimise outcomes. Neuropsychiatric outcomes do not seem to be affected by microembolisation of the brain during total joint arthroplasty.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 23 - 23
1 Feb 2012
Johnson S Newman J Jones P
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Background

Unicompartmental knee replacements (UKR) converted to total knee replacements (TKR) have often been viewed with scepticism because of the perceived difficulty of the revision and because revision procedures generally do less well than primaries.

Methods

This is a prospective review of TKRs converted from a UKR between 1982 and 2000. We present the survivorship of a 77 patient cohort and the clinical results of 35 patients. All information was recorded at the time of surgery onto a database and patients have been regularly reviewed since.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 152 - 152
1 Feb 2012
Ackroyd C Newman J Eldridge J Evans R
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Introduction

The Bristol Knee Group has prospectively followed the results of over 500 isolated patellofemoral arthroplasties. Initial experience with the Lubinus prosthesis was disappointing. The main causes of failure were mal-tracking and instability leading to excessive polythene button wear and disease progression in the tibio femoral joint.

This experience resulted in the design of a new prosthesis to correct the tracking problems and improve the wear. We have now performed over 425 Avon arthroplasties with a maximum follow-up of 9 years.

Results

Survivorship at 5 years and the functional outcome have been reported with 95.8% survivorship, and improved function with Oxford score from 18 to 39 points out of 48. There have been 14 cases with mal-tracking (3%). Several of these cases have required proximal or distal realignment with the Elmslie or Insall procedures. Two knees with patella alta required distalisation of the tibial tubercle. Symptomatic progression of the arthritic disease in the medial or lateral tibio-femoral compartments has occurred in 28 cases (7%) causing recurrent joint pain. Radiographic follow-up has shown a higher rate of disease progression emphasising the importance of careful assessment of patients prior to operation.

We have investigated 8 cases of persistent unexplained pain. Analysis of these cases suggests 3 possible causes. An extended anterior cut leading to overstuffing, insufficient external rotation and over sizing of the femoral component leading to medial or lateral retinacular impingement. Six of these cases have been successfully treated by revision of the femoral component leading to dramatic resolution of the symptoms.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 309 - 309
1 Jul 2011
Phadnis J Trompeter A Gallagher K Wan E Elliott D Newman K
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Aim: To assess mid to long-term functional and symptomatic outcome after internal fixation of the distal radius.

Methods: All patients operated upon between June 2004 and October 2007 were retrospectively assessed using the ‘Disabilities of arm, shoulder and hand’ (DASH, range 0–100), and Mayo wrist (range 0–100) functional scoring systems. Fractures were classified according to the AO system. All patients were treated in one unit by the same group of surgeons using standard accepted techniques. Revision operations and patients treated at greater than four weeks after injury were excluded. Radiographic analysis of time to union was also performed.

Results: 201 patients underwent surgical fixation of which, 183 patients were contactable for follow up (9% loss). Only these patients were included in the study. Mean age was 62.5 years. Mean follow up time was 30 months. Mean time to surgery was eight days. 74% had good/excellent Mayo and 75% good/excellent DASH scores. 2% of patients had a poor outcome with both scores. 28 % reported no functional or symptomatic deficit. There was a 14% overall complication rate (6% major). Mean time to union was 8.39 weeks. Time to union increased with advancing AO grade. There was no significant difference in scores with regard to postoperative immobilisation, time to surgery, time to follow up, patient age, surgeon grade or fracture type.

Conclusion: This is one of the largest series of its type and the results compare favourably with other published operative and non-operative treatment modalities. This is a safe, reproducible technique with excellent functional outcome and is recommended as the treatment of choice when surgery is indicated for these fractures.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 541 - 541
1 Oct 2010
Newman J Robinson J
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Background: Although many knee surgeons routinely perform unicompartmental replacement (UKR) for medial compartment arthrosis there is still reluctance to perform lateral UKR’s as they are generally thought to be less satisfactory. The purpose of the present study was to prospectively compare the outcome of lateral UKR’s with medial UKR’s using the AMC Uniglide knee implant.

Methods: Between 2002 and 2005, 29 lateral fixed bearing AMC Uniglide UKR’s were performed at our unit. American Knee Society (AKS), Oxford and WOMAC scores were recorded pre-operatively and at two years post-op and compared with the results of 50 medial mobile bearing and 50 medial fixed bearing AMC Uni-glide UKR’s performed during the same time period. Data was acquired by a research nurse and recorded prospectively on the Bristol Knee Database. The mean ages of the patients were: 63 years in the lateral UKR group was, 62 years in the medial mobile bearing group and 69 in the medial fixed bearing group. The groups were equally sex matched with a predominate number of females in each group. There was no difference between the pre-operative scores for the 3 groups.

Results: At one-year review, the 3 groups had similar mean scores: (table removed)

Conclusions: This study suggests that at two years the quality of outcome of Lateral UKR’s is at least equivalent to both fixed and mobile bearing medial compartment UKR’s. However, continued long-term survivorship studies are needed to assess failure rates of Lateral fixed bearing UKR’s and particularly to evaluate progression of arthritis in the medial compartment. The procedure should form part of the knee surgeons’ armamentarium, but the differences in the operative techniques for lateral and medial UKR must be appreciated.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 541 - 541
1 Oct 2010
Newman J Ackroyd C Robinson J
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Although good long term results for fixed bearing uni-compartmental knee replacements (UKRs) have been reported mobile bearings predominate in some parts of the world. Three prospective studies have been undertaken comparing the short and medium term outcomes of fixed and mobile UKRs.

A 5 year comparative cohort study of 47 Oxford mobile bearing and 57 St Georg Sled fixed bearing UKRs.

A 2 year study of 50 fixed and 50 mobile bearing AMC Uniglide UKRs.(The implant system allows implantation of either a fixed or mobile tibial component with the same femoral component.)

The 1 year results of a randomised controlled trial of 38 fixed and 33 mobile AMC Uniglide UKRs in patients under 70.

In all groups the preoperative sex mix, average age and knee scores were extremely similar.

All patients were assessed both pre and postoperatively by a research nurse and radiographs were taken; the results were entered on the Bristol Knee database.

Results:

Multiple problems were encountered, perhaps because of the introduction of MIS, but at 5 years 11 Oxford and 4 Sleds had failed. The major problem with the mobile bearing implant was instability though tibial fractures were also seen. Both groups had three cases of arthritic progression and loose cement was seen twice in the fixed bearing group.

– Amongst the remaining patients the median scores for the Sled were better. Bristol Knee Score (Max 100) 95:90; Oxford (Max 48) 39:37; and reduced WOMAC (Best score 12) 18:24.

2 bearing exchanges and 3 revisions were needed in the mobile group with none in the fixed group. Again all scores were better for the fixed group. American Knee Score (AKS) (Max 200) 195:185; Oxford (Max48) 39:37; and reduced WOMAC (Max 12) 19:20.

One fixed bearing implant had been revised but none in the mobile group, however 3 randomised to receive a mobile bearing had a fixed bearing inserted because the surgeon was unhappy about bearing stability; all three are doing well. All knee scores at one year show the fixed bearing implant to be performing better. AKS (Max 200) 194:173; Oxford (Max48) 39:33; and WOMAC(Max) 12 18:22.

Conclusion. Although theoretically mobile bearings will give greater longevity there is frequently a short term price to pay particularly when the procedures are performed by inexperienced surgeons and trainees. Since the wear properties of polyethylene have improved in recent years these studies suggest that a fixed bearing option can be used more safely in many patients.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 414 - 414
1 Sep 2009
Ackroyd C Eldridge J Newman J
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Introduction: The Bristol Knee group has performed over 600 patellofemoral arthroplasties in the last 18 years. Experience with the Lubinus prosthesis led to the development of the Avon Prosthesis. In the last 11 years we have prospectively recorded the results of over 470 consecutive Avon arthroplasties. The main cause of the 9.5% failure is arthritic disease progression in the tibiofemoral compartments.

Patients and Method: Over the last 11 years we have identified 21 patients from our own series and from tertiary referrals that have persistent pain, which was mainly due to technical error rather than arthritic disease progression. The causes can be classified into three main reasons: First, an incorrect anterior cut in the saggital plane which was cut in either too much flexion or extension. Second, the anterior cut had inadequate external rotation, which should be 3–6 degrees to lateralise the groove and facilitate correct tracking. Third, the prosthesis was oversized in several cases leading to retinacular impingement.

Results: The overall results followed up to 10 years showed excellent and consistent improvement in both pain and function as judged by the WOMAC 12 scale. Of those patients with persistent pain, seven had the femoral component revised to either resize the prosthesis or revise the alignment of the anterior resection and correctly inset the prosthesis, with good results. Ten cases were revised to a total knee replacement. In the remaining cases, two had an Insall realignment, one a patella distalisation, and in one no treatment was required. As a permanent solution new instruments were designed to reduce the incision size and increase the accuracy of the saggial alignment and to create an exact amount of external rotation.

Conclusion: The lessons from 11 years experience with the Avon arthroplasty has led to the development of improved instrumentation which should reduce the failures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 416 - 417
1 Sep 2009
Walton M Newman J
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Objectives: This study aims to assess the psychological profile of patients prior to total knee replacement, medial unicompartmental knee replacement and patellofemoral joint replacement and determine its effect on outcome.

Methods: 113 patients were identified (41 TKR, 37 UKR and 35 PFJR). All patients had mental health assessed preoperatively using SF-12. From the 12 questions a mental and a physical summary score can be calculated (MCS and PCS). The reduced WOMAC score was used pre-operatively to assess knee function and symptoms and then recorded at 8 and 24 months post-operation to assess outcome.

Results: 54% of the patients had pre-operative psychological distress. There was no statistically significant difference demonstrated between them mean MCS scores between the three operation groups. Pre-operative MCS had a significant effect such that increasing psychological distress lead to a worse twenty-four month outcome (p = 0.016). The effect of MCS is most marked in postoperative pain levels (p = 0.008) compared to function (p = 0.016). The mean 24-month rWOMAC in the severely distressed group (MCS< 40) was 28.4 compared to 17.4 in the psychologically well group (MCS> 60).

Conclusions: Pre-operative mental function prior to knee arthroplasty may provide useful information to guide patients as to their expected outcome in the consent process. Those patients with a very high mental component may be counseled to that although their distress is likely to improve with surgery, their eventual outcome may be worse. The effect of MCS may however only be clinically relevant in those patients with severe mental symptoms.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 426 - 426
1 Sep 2009
Reilly KA Barker KL Shamley D Newman M
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This observational study was undertaken to explore the relationship of the foot posture of patients with Medial Compartment Osteoarthritis of the knee (MCOA), patients with hip osteoarthritis (OA) and a healthy control group, using the Foot Posture Index (FPI). Goniometric measurement of talocrural dorsiflexion was also included.

The relationship of foot posture to MCOA and hip osteoarthritis OA has not been explored although in other medical fields, such as neurology and sports medicine, the relationship between foot posture, lower limb pain and function has been acknowledged. In view of the current high incidence of lower limb OA, any investigation of associations that may lead to improved assessment and conservative management is worthy of consideration.

Currently, systematic examination of the foot is not undertaken in routine clinical assessment of patients with lower limb OA and, if this were to be introduced, there would be difficulty in selecting suitable clinical outcome measures. The recent development of the Foot Posture Index (FPI) has addressed the need for a diagnostic clinical tool that measures foot posture in multiple planes and anatomical segments

Sixty participants took part: twenty patients with radiographic and clinical evidence of MCOA grade IV, twenty patients with radiographic and clinical evidence of stage IV OA hip, and twenty age-matched healthy volunteers as a control group.

A one way Analysis of variance (ANOVA) was performed to investigate any differences between the 3 groups for foot posture using FPI scores and talocrural dorsiflexion measurements. This showed that there were significant differences between the groups (p< 0.001). Patients with MCOA had a high positive FPI score (indicating a pronated foot), patients with hip OA had a low negative FPI score (indicating a supinated foot). The healthy controls had a normal score distributed over a wider range than the other two groups. In addition, the results of the Pearsons test indicate that the FPI correlated positively with talocrural dorsiflexion (r = 0.55, p< .001).

Differences in foot characteristics may be influenced by specific treatment modalities such as gait reducation, orthotic provision, specific lower limb strengthening and stretching exercises. Foot assessment might therefore be a useful adjunct to conservative management of both MCOA and hip osteoarthritis.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 48 - 48
1 Mar 2009
Bray R Steele R Newman J Hutabarat S Ackroyd C
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Purpose of Study: Fixed bearing unicompartmental knee replacement (UKR) has become popular since several series have now shown good 10 year survivorship and excellent function. However little is known about survival during the second decade.

Method: From the Bristol database of over 4000 knee replacements 203 St. Georg Sled UKR’s which had already survived 10 years were identified. The mean age at surgery was 67 years (48–85), with 64% being female. This cohort has been further reviewed at an average of 14.8 years (10–30) from surgery to determine survivorship and function.

Results: Survivorship during the second decade was 87.5%. 58 patients (69 knees) had died with implant in situ and only 2 after revision. A further 15 UKR’s have been revised at an average of 13 years post op; 7 for progression of disease in the opposite compartment, 4 for tibial loosening, 3 for polyethylene wear, 2 for femoral component fracture and 2 for infection.

99 knees were followed for 15 years, 21 knees for 20 years and four for 25 or more years. The average Bristol knee score of the surviving knees fell from 86 to 79 during the second decade, largely as a result of aging.

A previous study of the St Georg. Fixed bearing UKR showed an 89% 10 year survivorship and this is now extended to 82% at 15 years and 76.5% at 20 years.

Conclusion: Satisfactory survival of fixed bearing UKR can be achieved in the second decade suggesting that the indications for mobile bearings require careful definition since there is a higher incidence of complications in many people’s hands.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 72 - 72
1 Mar 2009
HASSABALLA M PORTEOUS A Newman JH
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Introduction: There is an impression among Orthopaedic surgeons that mobile bearing knee replacement has a better functional outcome than fixed bearing knee replacement. Since kneeling demands a high level of function after knee replacement this study was undertaken to see if mobile bearings in either total or unicompartmental replacement conferred an advantage.

Methods: A prospective randomised study of 207 TKR patients receiving the same prosthesis (Rotaglid, Corin, UK) was performed. Patients were randomised into a mobile bearing group (102 patients with a mean age of 53 years) and a fixed bearing group (105 patients with a mean age of 55 years). Data was also prospectively collected on 215 UKR patients who received the same unicompartmental implant (AMC, Uniglide, Corin, UK). 136 patients (Mean age: 62 yrs) had a mobile insert and 79 (mean age: 65 yrs) a fixed insert.

All patients completed the Oxford Knee Questionnaire preoperatively as well as at 1 and 2 years postoperatively. Their stated kneeling ability and total scores were analysed with a perfect score for kneeling ability being 4, and 48 the maximum total score.

Results: In all groups both the kneeling ability and the total scores improved markedly from their preoperative state. At two years the total score for the fixed bearing devices was marginally better than for the mobile (Rotaglide 36;31 and Uniglide 37;33)

There was a more striking difference with respect to kneeling ability with the fixed bearing variants performing better, (Rotaglide 1.4; 0.9 and Uniglide 1.9; 1.4), However, the greatest difference was between the UKR and TKR groups (UKR 1.7; TKR 1.2). Pre-operatively less than 2% of TKR patients (7% of the UKR patients) could kneel. Post-operatively, the patients’ kneeling ability improved with 21% for the mobile bearing, 32% of fixed bearing UKR patients. The TKR patients kneeling ability was 13% of the mobile, 26% of fixed bearing patients were able to kneel with little or no difficulty. In all groups the stated kneeling ability was poor with less than 50% of any group being able to kneel with ease or only minor difficulty.

Conclusion: Those undergoing UKR appeared to perform better than those with a TKR. None of the forms of knee replacement used resulted in good kneeling ability, though this function was improved by arthroplasty in all groups. Mobile bearing inserts


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 34 - 34
1 Mar 2009
Clare T Newman J Ackroyd C Evans R
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Since 1996 over 400 isolated patellofemoral replacements using the Avon prosthesis have been undertaken in Bristol. As a result of the usually gratifying outcomes seen in patients over 55 years old, the indications for this surgery were soon extended to include the many younger patients who have severely disabling patellofemoral disease. We present results from a prospective cohort study of patients under 55 years of age at the time of surgery.

110 knees in 86 patients (median age 47 years, range 24–54) have been treated with Avon patellofemoral replacement (88 in females and 22 in males). Diagnoses included lateral facet OA (59 knees), patella dislocation (25 knees), trochlear dysplasia (41 knees) and post patellectomy instability (7 knees). 79 knees had undergone previous surgery. 17 knees required additional intra-operative procedures including 11 lateral releases and 2 patella realignments. All patients were assessed pre-operatively and at regular intervals using the Oxford, Bristol and WOMAC scores.

All knees were scored preoperative and only one knee has been lost to follow-up due to the patient’s death, which was unrelated to surgery. Post-operative Oxford knee scores have been obtained for 106 knees with follow-up between 8 months and 8 years (mean follow-up 24 months). The mean Oxford score improved from 18 preoperatively to 31 at latest review. Bristol and WOMAC scores showed similar improvements. 16 knees required post-operative additional procedures including 6 lateral releases, 3 patella realignments and 11 revisions. Of the revisions 5 were for progression of tibiofemoral OA but none of these were knees with trochlear dysplasia. Equally good mean scores were seen when comparing patients with the 3 main underlying pathologies (trochlear dysplasia, patellar dislocation and lateral facet OA). At least 37% of the patients studied had pre-existing trochlear dysplasia and the majority of these patients report onset of symptoms, often patellar dislocation, in the first three decades of life. More than 90% of patients were overweight or obese according to their BMI at the time of surgery.

Many of this type of patient, with disabling symptoms, wish to “live now”. The short-term improvements are frequently dramatic. As yet there is no suggestion of prosthetic failure. Revision presents little difficulty since minimal bone is resected in the primary proceedure. Radiological deterioration of the tibio femoral joint is seen in some cases of primary OA but not with trochlear dysplasia.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 1 | Pages 52 - 57
1 Jan 2009
Newman J Pydisetty RV Ackroyd C

Between 1989 and 1992 we had 102 knees suitable for unicompartmental knee replacement (UKR). They were randomised to receive either a St Georg Sled UKR or a Kinematic modular total knee replacement (TKR). The early results demonstrated that the UKR group had less complications and more rapid rehabilitation than the TKR group. At five years there were an equal number of failures in the two groups but the UKR group had more excellent results and a greater range of movement.

The cases were reviewed by a research nurse at 8, 10 and 12 years after operation. We report the outcome at 15 years follow-up. A total of 43 patients (45 knees) died with their prosthetic knees intact. Throughout the review period the Bristol knee scores of the UKR group have been better and at 15 years 15 (71.4%) of the surviving UKRs and 10 (52.6%) of the surviving TKRs had achieved an excellent score. The 15 years survivorship rate based on revision or failure for any reason was 24 (89.8%) for UKR and 19 (78.7%) for TKR. During the 15 years of the review four UKRs and six TKRs failed.

The better early results with UKR are maintained at 15 years with no greater failure rate. The median Bristol knee score of the UKR group was 91.1 at five years and 92 at 15 years, suggesting little functional deterioration in either the prosthesis or the remainder of the joint. These results justify the increased use of UKR.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 575 - 575
1 Aug 2008
Porteous AJ Mulford JS Newman JH Ackroyd CE
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Purpose: Revision patellofemoral arthroplasty (PFA) is a relatively uncommon procedure, with no published reviews identified in the literature. Revision PFAs performed at our institution were reviewed to determine the reasons for PFA failure, the technical ease of revision and to document patient-reported outcomes after revision.

Methods: A prospective review of a cohort of 411 Avon PFA patients identified 31 subsequent revision knee procedures in 27 patients. Data was collected from the institution’s prospective data base, operative reports, X-rays and medical records. Post-operative knee scores (Oxford Knee Score, WOMAC Osteoarthritis Index, Bristol Knee Score) were available on 26 knees.

Results: The commonest reason for revision was progression of osteoarthritis (18 cases) followed by undetermined pain (7 cases). Patients with undetermined pain were found to be revised sooner than patients with disease progression (33 months vs 63 months) and also reported poorer outcome scores at 2 years post revision than the disease progression group.

Only two trochlea components were loose at the time of revision and one patella had a large amount of macroscopic wear. All other components were found to be well fixed with minimal wear at the time of revision. There were no difficulties in removing either component. No cases required augments or stemmed femoral components due to bone loss.

Patients undergoing revision surgery did report improvement in their post revision outcome scores compared with their pre-operative scores. The average Oxford Knee Score improved from 17 to 23, Bristol Knee Pain Scores improved from 11 to 20 and Bristol Knee Functional Scores improved from 15 to 16. These results are poorer than those recorded by the overall cohort of primary PFA.

Conclusion: PFA is easy to revise to a primary total knee. Results of revision knees are improved from pre-operative scores but not as good as expected.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 531 - 532
1 Aug 2008
Barker KL Newman MA Pandit H Murray DW
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Introduction: Metal-on-metal hip resurfacing arthroplasty (HRA) is currently recommended for younger, active patients with high expectations but information about outcomes is limited. Reports concentrate on wear, fracture rates and radiographic appearance, rather than function. Studies that report function do not describe rehabilitation protocols. This data is important to discussions about likely outcomes and restrictions prior to consent and to fully evaluate HRA.

Methods: Consecutive Conserve HRA operations were reviewed 1 year post-surgery. Function was assessed using 3 validated questionnaires; the OHS (Oxford Hip Score), HOOS (Hip Disability and Osteoarthritis Outcome Score) and UCLA Activity Scale. Complications, pain, ROM, muscle strength, single leg stand, walking and stair climbing ability were recorded.

Results: 125 HRA were reviewed (68 right, 57 left hips) in 120 patients (71 male, 49 female) of mean age 56 years. 86.7% recorded no complications, but 20% had pain at 3 months. The median OHS was 15, median UCLA 7 (active) and mean HOOS 82.78%. Operated hip flexors, extensors and abductors were weaker (p=0.000) and hip flexion ROM a mean 94.46 ± 12.71 (55–120) degrees. For 25% walking was limited, 7.6% needed a stick and 10% a stair rail. The OHS correlated with HOOS pain subscale (r=0.812, p=0.000), flexion ROM (r=0.426, p=0.000), hip extensor (r=0.359, p=0.000) and abductor (r=0.424, p=0.000) strength. Pain at 3 months correlated with the HOOS pain subscale (p=0.000, r= 0.503).

Discussion: Although outcomes were generally good with few complications, high levels of function and activity 25% had poor outcomes; with pain, restricted hip flexion, decreased strength, limited walking and functional problems, particularly putting on socks. Pain present at 3 months was associated with pain and worse function at 1 year. It is postulated this sub-optimal recovery may be related to current rehabilitation protocols adopted from THA and not tailored to HRA.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 579 - 579
1 Aug 2008
Gardner R Newman J
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Background: In the UK 80% unicompartmental knee replacements(UKRs) and 10% of total knee replacements(TKRs) use mobile bearings. It is suggested that mobile bearings are more physiological and wear less, however it is still unclear whether patients tolerate mobile bearing knee replacements as well.

Patients and methods: We report four prospective studies,. Two compared fixed with mobile bearings in TKR and two in UKR. The prostheses involved were fixed and mobile variants of the Rotaglide (TKR), Kinemax (TKR) and Uniglide (UKR). In addition the Oxford and St. George Sled UKRs were compared. All except the Uniglide study were randomized prospective trials (RCTs)

611 patients were involved with a mean age of 68 years. Residual pain following surgery was assessed with either the Oxford Knee Score (OKS) or the WOMAC score. The patients were followed up at one and two years postoperatively by a Research nurse and the findings recorded prospectively on the Bristol Knee database.

Results:

Study 1: Rotaglide. Prospective RCT. 171 patients. Mean pain score (OKS) Fixed bearing 15.4 v Mobile bearing 13.2. P= 0.012. Fixed bearing prosthesis caused significantly less pain.
Study 2: Kinemax. Prospective RCT. 198 patients. Mean pain score (WOMAC) Fixed bearing 8.9 v Mobile bearing 8.3. P = 0.443. Trend favouring fixed bearing.
Study 3: Uniglide Non-randomised trial. 184 patients. Mean pain score (WOMAC) Fixed bearing 7.6 v Mobile bearing 10.1. P < 0.001. Fixed bearing caused significantly less pain.
Study 4: St. George Sled v Oxford. Prospective RCT. 94 patients. Mean pain score (OKS) 15.8 v 13.9 . P= 0.058. Strong trend suggesting the Sled caused less pain.

Conclusion: Our data suggests that the fixed bearing knee replacements result in less residual pain than their mobile bearing counterparts, at least in the first two years following surgery.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 526 - 526
1 Aug 2008
Lakkireddi MP Gill MI Chan MJ Kotrba DM Newman-Saunders DT Marsh MG
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Background: The major problem achieving lumbar spinal fusion is developing pseudarthrosis. At present the gold standard in achieving fusion is the use of autograft from pelvis or posterior elements of the spine. However the potential limitations of insuffient quantity and donor site morbidity have led to search for bone graft alternatives like DBM which contains osteinductive BMPs.

Aims & Methods: A Prospective Randomized Control trial comparing the effectiveness of demineralised Bone Matrix (DBM Putty)/autograft composite with autograft in lumbar spinal fusion.

35 patients were included in the trial; they were randomized to have DBM and autograft on one side, and autograft alone on other side to side. Patients were followed up with interval radiographs for total of 24mons. To date 20 patients have completed minimum 12mons follow up. The mineralization of fusion mass lateral to the instrumentation on each side was graded Absent, Mild (< 50%), Moderate (> 50%) or Complete fusion (100%). The assessment was made by two orthopaedic consultants and a musculoskeletal radiologist who were blinded to graft assignment.

Results: The sex distribution was 11:9 male to females with a mean age of 55.2 (21–87 years) and an average follow up of 18mons (12–24mons). Nine patients had single level fusion and the remainder had more than one level fusion. At 12 months on the side of DBM, 15% (6 of 20) had complete fusion, 80% (16 of 20) had moderate fusion, and 5% had no fusion mass. During the same period on the other side, 25% did not show any sign of fusion. There was no correlation with number of levels, age or sex.

Conclusions: Osteoinductive properties of DBM would appear to help in achieving early and higher union rates in lumbar spinal fusion. DBM reduces the amount of harvested autograft graft and also minimises the morbidity of donor site complications.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 574 - 574
1 Aug 2008
Barton T White S Porteous A Mintowt-Czyz W Newman J
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Purpose: To review long-term outcome following knee arthrodesis, and compare this with patient outcome following revision knee arthroplasty.

Methods: Case notes and radiographs of patients who underwent arthrodesis using the Mayday nail were reviewed retrospectively for evidence of clinical and radiological union. Patients also completed an SF12 health survey and Oxford knee score in the form of postal questionnaires. Each patient was matched with patients who had undergone revision knee arthoplasty and the outcomes were compared.

Results: 19 patients were reviewed who underwent knee arthrodesis using a Mayday nail in two centres between 1993 and 2004. 18 cases had united clinically and radiologically with one case lost to follow-up. Mean SF12 scores of patients following knee arthrodesis indicated severe physical (28.8) but only mild mental (43.3) disabilities. The mean Oxford knee score in this group was 41.0. These results were comparable with matched patients following revision knee arthroplasty who scores 27.2 (physical) and 41.1 (mental) on the SF12, and a mean of 38.8 on the Oxford knee score.

Conclusion: Outcome scores following knee arthrodesis were similar to those following revision knee arthroplasty making it an option worth considering in selected patients requiring revision surgery.

Discussion: The Mayday nail provides a method of knee arthrodesis with a high union rate and an acceptable complication rate. Outcome scores following arthrod-esis were not dissimilar to those following revision total knee replacement. These results suggest that knee arthrodesis may be considered as an acceptable alternative to complex knee revision surgery.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 581 - 581
1 Aug 2008
Arastu M Vijayaraghavan J Robinson J Chissell H Hull J Newman J
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Background: We have noted a concerning number of early failures (as defined by revision) for Preservation medial mobile-bearing uni-compartmental knee replacements (UKR’s) implanted in our hospital. This study retrospectively reviewed the postoperative radiographs to see if these were as a result of surgical technical failure.

Methods: Between 2003 and 2004, 43 medial mobile-bearing Preservation UKR’s were implanted into 39 patients. The average age of the patients at the time of the index procedure was 61.4 years (range, 46–85), (20 males). The immediate post-operative radiographs were reviewed by 2 independent orthopaedic consultants and a registrar, who were blinded to the patient outcomes, using the radiographic criteria used for the Oxford UKR. We however, particularly tried to identify any medio-lateral offset between femoral and tibial components due to the constrained nature of the prosthesis. A compound error score for all other technical errors was also calculated for each patient.

Results: Six (13.9%) of 43 knees were revised (5 for persistent pain, 1 for tibial component subsidence). Technical errors were few and no correlation was found between post-operative radiographic appearances and the subsequent need for revision. The mean compound error score (maximum value 18) was 4.5 (range, 2–9) in the revision cases and in the non revised cases 3.2 (range, 0–8).

Conclusions: We believe this study gives credence to the opinion that the DePuy Preservation mobile-bearing implant has design faults and is over-constrained leading to early failures in some cases.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 580 - 580
1 Aug 2008
Hassaballa M Porteous A Newman JH
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Introduction: There is an impression among Orthopaedic surgeons that mobile bearing knee replacement has a better functional outcome than fixed bearing knee replacement. Since kneeling demands a high level of function after knee replacement this study was undertaken to see if mobile bearings in either total or unicompartmental replacement conferred an advantage.

Methods: A prospective randomised study of 207 TKR patients receiving the same prosthesis (Rotaglid , Corin, UK) was performed. Patients were randomised into a mobile bearing group (102 patients with a mean age of 53 years) and a fixed bearing group (105 patients with a mean age of 55 years).

Data was also prospectively collected on 215 UKR patients who received the same Unicompartmental implant (AMC, Uniglide, Corin, UK). One hundred and thirty six patients (Mean age: 62 yrs) had a mobile insert and 79 (mean age: 65 yrs) a fixed insert.

All patients completed the Oxford Knee Questionnaire preoperatively as well as at 1 and 2 years postoperatively. Their stated kneeling ability and total scores were analysed with a perfect score for kneeling ability being 4 and 48 the maximum total score.

Results: In all groups both the kneeling ability and the total scores improved markedly from their preoperative state. At two years the total score for the fixed bearing devices was marginally better than for the mobile (Rotaglide 36;31 and Uniglide 37;33)

There was a more striking difference with respect to kneeling ability with the fixed- bearing variants performing better, (Rotaglide 1.4; 0.9 and Uniglide 1.9; 1.4), However, the greatest difference was between the UKR and TKR groups (UKR 1.7; TKR 1.2). Pre-operatively less than 2% of TKR patients (7% of the UKR patients) could kneel. Post-operatively, the patients’ kneeling ability improved with 21% for the mobile bearing, 32% of fixed bearing UKR patients.

The TKR patients kneeling ability was 13% of the mobile, 26% of fixed bearing patients were able to kneel with little or no difficulty. In all groups the stated kneeling ability was poor with less than 50% of any group being able to kneel with ease or only minor difficulty.

Conclusion: Those undergoing UKR appeared to perform better than those with a TKR. None of the forms of knee replacement used resulted in good kneeling ability, though this function was improved by arthroplasty in all groups. Mobile bearing inserts did not confer any advantage with respect to kneeling and in fact performed worse with regard to this particular knee function.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 324 - 325
1 Jul 2008
Ackroyd CE Newman JH Evans R Joslin CC
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Objective: To review the results of the Avon patellofemoral arthroplasty at 5 to 8 years.

Methods: The Avon patellofemoral arthroplasty was introduced in clinical practice in September 1996. We present a prospective cohort review of all patients treated in the first three years. Patients were evaluated using the Bristol knee score (BSK), the Melbourne patella score (MPS) and the Oxford knee score (OKS).

Results: 109 patellofemoral arthroplasties were performed in 92 patients between September 1996 and November 1999. The median age was 68 years (range 46 to 86 years). Nine patients (12 knees) died and two patients (two knees) were unfit for follow-up. Ten knees in 9 patients were lost to follow-up giving a follow-up rate of 89%. The mean period of follow-up was 5.6 years.

The median pain score rose from 15/40 pre-operatively to 40 points at eight years. The median (MPS) rose from 10/30 points pre-operatively to 25 points at eight years. The median (OKS) rose from 18/48 pre-operatively to 38 at eight years. 87% of knees had mild or no pain at eight years. There were no cases of failure of the prosthesis itself. All 15 revisions resulted from progression of arthrititis in the tibio-femoral joint. The five-year survival rate for all causes with 86 cases at risk was 96%.

Conclusions: The results show that this type of arthroplasty can give predictable pain relief and excellent functional improvement in patients with isolated patello-femoral arthritis. Disease progression is the main reason for revision to total knee replacement and great care is required in assessing the indications for this procedure.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Kulkarni MM Eldridge JD Newman JH
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Introduction: Anterior Knee pain is a very common presentation in Orthopaedic out patient clinics. However, Trochlear Dysplasia as a condition is still not very well understood.

Materials and Methods: Operative findings in patients undergoing Trochleaplasty and in young patients undergoing Patella-femoral arthroplasty were studied. Patients having trochlear dysplasia were identified. All these patients were sent a questionnaire to explore the variety of symptoms they experienced. 87 patients were identified for the study. 71(82%) patients responded to the questionnaire.

Results: Two subgroups were identified, one with dislocation of patella and the other without dislocation of the patella. Patients in patella dislocation group were younger (12 years vs 24) than those who presented without dislocation of patella. Patella dislocation group had more patients with anterior knee pain (71% vs 52%) as teenagers as compared to the group without dislocations. Symptoms such as giving way, lack of trust and unable to participate in sports were more commonly seen in the group with patella dislocation whereas, limited walking distance and difficulty with climbing the stairs were more commonly seen in the group without dislocation. Symptoms such as pain, catching and locking were seen equally amongst the two groups.

Conclusion: We believe that the patients with trochlear dysplasia have a bimodal presentation. Patients with dislocation of patella present earlier than those without patella dislocation. These two groups also have different symptoms at presentation. It is important to identify these subgroups correctly for appropriate management.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 324 - 324
1 Jul 2008
Steele RG Newman JH Hutabarat S Evans R Ackroyd CE
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Purpose of Study: Fixed bearing unicompartmental knee replacement (UKR) has become popular since several series have shown good 10 year survivorship and excellent function. However little is known about survival during the second decade.

Method: From the Bristol database of over 4000 knee replacements 203 St. George Sled UKR’s which had already survived 10 years were identified. The mean age at surgery was 67 years (48–85), with 64% being female. This cohort has been further reviewed at an average of 14.8 years (10–30) from surgery to determine survivor-ship and function.

Results: Survivorship during the second decade was 87.5%. 58 patients (69 knees) had deceased with implant in situ, only 2 after revision. A further 15 UKR’s have been revised at an average of 13 years post op; 7 for progression of disease, 4 for tibial loosening, 3 for polyethylene wear, 2 for femoral component fracture and 2 for infection.

99 knees were followed for 15 years and 21 knees for 20 years. The average Bristol knee score of the surviving knees fell from 86 to 79 during the second decade.

A previous study showed an 89% 10 year survivor-ship and this is now extended to 82% at 15 years and 76.5% at 20 years.

Conclusion: Satisfactory survival of fixed bearing UKR can be achieved in the second decade suggesting that the indications for mobile bearings require careful definition since there is a higher incidence of complications in many people’s hands.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 329 - 329
1 Jul 2008
Davis CR Newman JH Davies AP
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The purpose of this study was to determine the incidence of revision total knee replacement (TKR) within 5 years of the index procedure at a large multi-surgeon unit using a single prosthesis and to determine the cause of failure of those implants.

This was a retrospective review of all primary Kine-max Plus TKR performed at the Avon Orthopaedic Center between 1.1.1990 and 1.1.2000. Cases were identified that required revision arthroplasty in any form within 5 years of the index procedure. Case notes and Xrays were reviewed to determine causes of failure.

There were 2826 primary Kinemax Plus TKR performed during the study period. Of these 20 were known to have required revision surgery within 5 years. 8 were revised for deep infection of the prosthesis and 12 for aseptic causes. The overall incidence of premature failure of the Kinemax Plus TKR at 5 years was 0.71%. The incidence of aseptic premature failure at 5 years was 0.42%. Detailed examination of the clinical records indicated that some form of technical error at the time of the index arthroplasty was responsible for the early failure of 6 prostheses. This equates to 0.21% of the procedures performed. Aseptic loosening of the remaining 6 cases could not be attributed to a specific cause.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Clare TD Newman JH
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Introduction: Following previously gratifying results in older patients the study aims to quantify the outcomes and identify any contraindications in patient selection for patello-femoral replacements using the Avon pros-thesis in patients under 55 years old.

Method: We present early outcome results for a prospective cohort study of patients under 55 years of age.110 knees in 86 patients (median age 47years, range 25–54) have been treated with Avon patello-femoral replacement (88 in females and 22 in males). Diagnoses included lateral facet OA (59 knees), patella dislocation (36 knees), trochlear dysplasia (39 knees) and post patellectomy instability (7 knees). 108 knees had undergone previous surgery. 14 knees required additional intra-operative procedures (including 11 lateral releases and 2 patella realignments). All patients were assessed pre-operatively using the Oxford, Bristol and WOMAC scores.

Results: No knees have been lost to follow-up. 82 knees have post operative scores available (mean follow-up 27 months). 8 have been revised (6 due to progression of OA). The mean Oxford, Bristol and WOMAC scores all improved: 18 to 32, 56 to 83 and 39 to 25 respectively. Asymptomatic deterioration of the tibio femoral joint is seen in some cases of primary OA but not with trochlear dysplasia. 21 knees required post-operative additional procedures including 6 lateral releases, 3 patella realignments and 5 revisions. Equally good results were seen when comparing patients with the 3 main diagnoses. Trochlear dysplasia is strongly predicted by young age at onset of symptoms and patellar dislocation.

Conclusion: Many of this type of patient, with disabling symptoms, wish to “live now”. The short-term improvements are frequently dramatic. Comparison of underlying pathologies has not identified groups that are performing less well to suggest restricting current indications. As yet there is no suggestion of prosthetic failure. Revision has presented little difficulty since minimal bone is resected primarily.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 7 | Pages 879 - 884
1 Jul 2008
Porteous AJ Hassaballa MA Newman JH

We identified 148 patients who had undergone a revision total knee replacement using a single implant system between 1990 and 2000. Of these 18 patients had died, six had developed a peri-prosthetic fracture and ten had incomplete records or radiographs. This left 114 with prospectively-collected radiographs and Bristol knee scores available for study. The height of the joint line before and after revision total knee replacement was measured and classified as either restored to within 5 mm of the pre-operative height or elevated if it was positioned more than 5 mm above the pre-operative height. The joint line was elevated in 41 knees (36%) and restored in 73 (64%).

Revision surgery significantly improved the mean Bristol knee score from 41.1 (sd 15.9) pre-operatively to 80.5 (sd 15) post-operatively (p < 0.001). At one year post-operatively both the total Bristol knee score and its functional component were significantly better in the restored group than in the elevated group (p < 0.01). Overall, revision from a unicondylar knee replacement required less use of bone graft, fewer component augments, restored the joint line more often and gave a significantly better total Bristol knee score (p < 0.02) and functional score (p < 0.01) than revision from total knee replacement.

Our findings show that restoration of the joint line at revision total knee replacement gives a significantly better result than leaving it unrestored by more than 5 mm. We recommend the greater use of distal femoral augments to help to achieve this goal.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 17 - 18
1 Mar 2008
Patel R Stygall J Harrington J Harrison M Newman S Haddad F
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To quantify the intraoperative cerebral microemboli load during primary total knee arthroplasty (TKA) using transcranial Doppler ultrasound and to investigate whether a patent foramen ovale influences cerebral embolic load in general.

Patients undergoing primary TKA, with no history of stroke, TIA, ongoing CNS disease or alcoholism were included. All operations were carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli l oad was recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis. Patent foramen ovale detection was performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre technique and TCD. Timing of specific surgical steps was recorded for each operation and emboli load calculated for that period.

Results: 50 TKA patients were studied (31 females, 19 males); 28 right and 22 left TKAs were performed. Cerebral microembolisation occurred in 19 patients (42%). Mean microembolic load was 3.56 per patient (range 0–21). PFO was detected in 9 patients (18%). Two thirds of PFO positive patients displayed cerebral microemboli. However, 36.6% (n=15) of PFO negative patients also displayed microemboli intraoperatively. Deflation of the tourniquet was followed by a larger microembolic load than the other phases of the operation.

Conclusion: Intraoperative cerebral microembolisation occurs in a significant proportion of patients during total knee arthroplasty. The presence of a patent foramen ovale does not appear to influence the incidence microemboli intraoperatively. Specific surgical activities are associated with generating greater embolic loads. These questions will be comprehensively assessed in the larger study currently underway.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 167 - 167
1 Mar 2008
Hollinghurst D Stoney J Ward T Gill H Beard D Newman J Murray D
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Medial unicompartmental replacement (UKR) has been shown to have superior functional results to total knee replacement (TKR) in appropriately selected patients, and this has been associated with a resurgence of interest in the procedure. This may relate to evidence showing that the kinematic profile of UKR is similar to the normal knee, in comparison to TKR, which has abnormal kinematics. Concerns remain over the survivorship of UKR and work has suggested the anterior cruciate ligament (ACL) may become dysfunctional over time. Cruciate mechanism dysfunction would produce poor kinematics and instability providing a potential mechanism of failure for the UKR.

Aim: To test the hypothesis that the sagittal plane kinematics (and cruciate mechanism) of a fixed bearing medial UKR deteriorate over time (short to long term).

A cross sectional study was designed in which 24 patients who had undergone successful UKR were recruited and divided into early (2–5 years) and late (> 9 years) groups according to time since surgery. Patients performed flexion/extension against gravity, and a step up. Video fluoroscopy of these activities was used to obtain the Patellar Tendon Angle (PTA), the angle between the long axis of the tibia and the patella tendon, as a function of knee flexion. This is a previously validated method of assessing sagittal plane kinematics of a knee joint.

This work suggests the sagittal plane kinematics of a fixed bearing UKR is maintained in the long term. There is no evidence that the cruciate mechanism has failed at ten years. However, increased tibial bearing conformity from ‘dishing’, and adequate muscle control, cannot be ruled out as possible mechanisms for the satisfactory kinematics observed in the long term for this UKA.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 143 - 144
1 Mar 2008
Friedman R Longo J Cherry K Newman M Jessup D Bal S
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Purpose: Ceramic/ceramic bearing surfaces have the advantage of significantly decreased wear and high biocompatibility compared to CoCr/PE or ceramic/PE. The purpose of this randomized, controlled, multi-center, prospective study was to evaluate the clinical and roentgenographic results of 469 ceramic/ceramic versus 321 ceramic/PE THA at a 2 to 7 year follow-up.

Methods: The ceramic/ceramic THA had a polished alumina femoral head articulating with a polished alumina acetabular liner seated into the metal acetabular shell designed to avoid any impingement of the ceramic liner on the femoral component. Evaluations were completed preoperatively, at 6 months and yearly postoperatively.

Results: Mean age of the 790 patients was 59 years, with slightly more females. There were no significant demographic differences between the two groups. The main diagnoses were OA in 74% and osteonecrosis in 19%. Preoperatively the mean Harris Hip Score (HHS) and WOMAC scores were 44 and 41, respectively, and did not differ significantly between the two groups. At follow-up, the mean HHS was 93 for the ceramic/ ceramic THA and 93 for the ceramic/PE THA. The mean WOMAC scores showed no differences at follow-up. Roentgenographic analysis revealed one acetabular cup migration with a PE liner. One ceramic liner fractured upon insertion that was not properly positioned prior to impaction. Otherwise, there were no revisions or complications related to either bearing surface.

Conclusions: This short-term study has demonstrated efficacy and safety of a ceramic/ceramic bearing surface compared to the standard ceramic/PE surface currently used in clinical practice, with no failures or complications related to the bearing surface. Further follow-up is indicated to determine the long-term outcome.

Funding : Commerical funding

Funding Parties : Encore Orthopaedics


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 18 - 19
1 Mar 2008
Prem H Aravindan S Mowbray M Newman-Sanders A
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70 patients who underwent dynamic MRI scanning for chronic anterior knee pain were retrospectively evaluated. All patients had been symptomatic for over a year. 43 patients had been treated conservatively and 27 had undergone surgical procedures (arthroscopy -13, lateral release- 9, tibial tubercle transfer 5). The extent of subluxation, tilt and cartilage abnormalities on MRI scans, during resisted extension were assessed. Functional scoring (Oxford, Lysholm and Tegner scores) was done through questionnaires and correlated with the radiological findings.

54 (77%) patients were found to have some patellofemoral abnormality on the scans. Subluxation was the most common finding with mild subluxation in 30, moderate in 18 and severe in 17 knees. Mild tilt was seen in 26 knees and moderate to severe tilt in 14 knees. Tilt was found in association with subluxation except in 8 cases. Grade 1 and 2 cartilage wear were seen in 13 knees and Grade 3 and 4 in 21 knees.

The “Tibial Tubercle to Trochlear Groove distance” (TTD) was measured in all knees and correlated with subluxation. The average distance was 13.5mm, 13.6mm and 18.8mm for mild, moderate and severe subluxation respectively. All patients with a TTD _ 20mm had moderate or severe subluxation. The specificity of a TTD _ 20mm for severe maltracking was 100% but the sensitivity was only 42%.

The TTD appears to be the single most significant parameter determining patella tracking. We have proposed an algorithm for the surgical and non-surgical treatment of chronic anterior knee pain. We recommend lateral release for those with moderate and severe subluxation and a tibial tubercle transfer as well in those with a TTD _ 20mm. The functional scores did not zshow a significant correlation with the grading of subluxation.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 3 | Pages 310 - 315
1 Mar 2007
Ackroyd CE Newman JH Evans R Eldridge JDJ Joslin CC

We report the mid-term results of a new patellofemoral arthroplasty for established isolated patellofemoral arthritis. We have reviewed the experience of 109 consecutive patellofemoral resurfacing arthroplasties in 85 patients who were followed up for at least five years.

The five-year survival rate, with revision as the endpoint, was 95.8% (95% confidence interval 91.8% to 99.8%). There were no cases of loosening of the prosthesis. At five years the median Bristol pain score improved from 15 of 40 points (interquartile range 5 to 20) pre-operatively, to 35 (interquartile range 20 to 40), the median Melbourne score from 10 of 30 points (interquartile range 6 to 15) to 25 (interquartile range 20 to 29), and the median Oxford score from 18 of 48 points (interquartile range 13 to 24) to 39 (interquartile range 24 to 45). Successful results, judged on a Bristol pain score of at least 20 at five years, occurred in 80% (66) of knees. The main complication was radiological progression of arthritis, which occurred in 25 patients (28%) and emphasises the importance of the careful selection of patients. These results give increased confidence in the use of patellofemoral arthroplasty.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 9 | Pages 1164 - 1168
1 Sep 2006
Steele RG Hutabarat S Evans RL Ackroyd CE Newman JH

There have been several reports of good survivorship and excellent function at ten years with fixed-bearing unicompartmental knee replacement. However, little is known about survival beyond ten years.

From the Bristol database of over 4000 knee replacements, we identified 203 St Georg Sled unicompartmental knee replacements (174 patients) which had already survived ten years. The mean age of the patients at surgery was 67.1 years (35.7 to 85) with 67 (38.5%) being under 65 years at the time of surgery. They were reviewed at a mean of 14.8 years (10 to 29.4) from surgery to determine survivorship and function. There were 99 knees followed up for 15 years, 21 for 20 years and four for 25 years. The remainder failed, were withdrawn, or the patient had died.

In 58 patients (69 knees) the implant was in situ at the time of death. Revision was undertaken in 16 knees (7.9%) at a mean of 13 years (10.2 to 21.6) after operation. In seven knees (3.4%) this was for progression of arthritis, in three (1.5%) for wear of polyethylene, in four (2%) for tibial loosening, in two (1%) for fracture of the femoral component and in two (1%) for infection. Two knees (1%) were revised for more than one reason.

The mean Bristol knee score of the surviving knees fell from 86 (34 to 100) to 79 (42 to 100) during the second decade. Survivorship to 20 years was 85.9% (95% CI 82.9% to 88.9%) and at 25 years was 80% (95% CI 70.2% to 89.8%). Satisfactory survival of a fixed-bearing unicompartmental knee replacement can be achieved into the second decade and beyond.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 259 - 259
1 May 2006
Davies H Khan OH Weale AE Newman JH
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Purpose of study: To examine the fate of the non operated on compartment of the knee, following unicompartmental knee replacement (UKR), by radiological assessment 10 years after operation.

Summary of methods and results: A total of 50 UKRs were performed on 45 carefully selected patients between 1989 and 1992. Fifteen patients died, two patients were lost to follow-up and two knees were revised. The radiographs of the remaining 30 knees were reviewed three times by blind and randomised assessment using Ahlback and Altman scoring systems to measure the progression of osteoarthritis within the joints. Standard long-leg weight-bearing anteroposterior views of the knee and skyline views of the patello-femoral joint were taken before, at eight months and ten years after operation. Two knees showed evidence of progression of osteoarthritis within the patello-femoral joint and three knees showed some progression of the opposite tibio-femoral compartment.

Statement of conclusion: Our study provides evidence that after ten years progressive OA within the retained compartments following UKR is rare and usually minor.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 256 - 256
1 May 2006
Hassaballa MA Mehendale S Porteous AJ Newman JH
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Aim: To assess the results of aseptic and aseptic cases using the PFC/TC3 system, and to correlate this with the restoration of joint line height.

Method: 148 patients underwent revision TKR using the PFC/TC3 system. No re-revision cases were included in this series. Data was prospectively collected (using the Bristol Knee Score) pre-operatively and at a mean of 4.2 years post-revision. 31 revisions were for infection and 53 revisions were for aseptic loosening. Revision for infection was done as a two-stage procedure and aseptic as a single operation. Measurements of the joint line height were made pre and post-operatively using Figgie’s method. The cases were divided into 3 groups on the basis of joint line restoration:

Lowered by more than 5 mm

Restored

Elevated more than 5 mm

Results: The mean pre-op total score for the infection group was 35/100 and 40/100 for the aseptic loosening group. The total score post-operatively was 67 for the infection group and 73 for the aseptic loosening group. The joint line was restored in 50% of infected cases and in 60% of aseptic loosening cases.

Conclusion: although the overall results were slightly less satisfactory for the infected revision group, there was no significant difference between the two groups either in total BKS scores or in reproduction of the joint line. The average outcome was much less good than for primary TKR.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 256 - 257
1 May 2006
Hassaballa M Weal A Porteous A Newman J
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Purpose: This study was carried out to compare the alteration in skin sensation following midline, medial and short medial incisions for knee replacement.

Method: 88 patients with 102 replaced knees were examined for altered skin sensation over the front of the knee, all were at least 18 months from their knee replacement. Twenty-one knees had a medial incision, 38 a midline incision and 43 a short medial incision for UKR.

A scale of −2 to +2 was used to measure different degrees of skin hypo or hyperaesthia. A purpose-designed grid, designed to fit different knee sizes, was used to record sensations. A computer programme was created to record all patients’ data including the length and shape of the incision in relation to anatomical landmarks.

A parallel histological study was carried out on 18 skin specimens taken from the 2 standard incisions. The specimens were prepared and stained for nerve endings. The number of nerve endings in each incision was calculated.

Results Histologically, less cutaneous nerve endings were seen in specimens from midline incisions than medial incisions.

Discussion: Altered skin sensation is unpleasant to many patients at least initially and may affect function especially kneeling. The midline line incision seems to produce less dermal parasthesia than the medial incision, this probably relates to both the wound position and the density of nerve endings. As expected, the length of incision correlated with the area of numbness when comparing short and long medial incisions.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 251 - 251
1 May 2006
Newman J Hendrix M
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Introduction: This study assesses the prevalence of trochlear dysplasia as a cause of patello-femoral arthritis (PFOA), though for many years the condition was scarcely recognised and not recorded.

Method: Since 1989 385 primary isolated patello-femoral replacements have been performed in Bristol for patello-femoral arthritis.

The diagnoses recorded were:

Lateral facet PFOA 227

Symmetrical PFOA 95

Medial facet PFOA 24

Dislocation 15

Subluxation 33

Post traumatic 6

Trochlear dysplasia was noted either retrospectively or as “other diagnosis” in only 10 cases between 1989 and 2003, however in the last year, the condition became recognised locally, and has been recorded in 11 of the 48 cases performed.

A recent review of 40 cases aged under 55 showed evidence of causative trochlear dysplasia in more than 50%.

This was based on:

Trochlear dysplasia recorded on operative note 8

A positive crossing sign on a true lateral xray 19

A sulcus angle > 144° 20

Conclusion: Trochlear dysplasia frequently leads to severe symptomatic patello-femoral arthritis, often at an early age, and can be helped by isolated patello-femoral replacement. Since only 38 of the 385 cases had undergone re-alignment procedures it seems likely that the condition initially presents in a variety of ways.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 257 - 257
1 May 2006
Hassaballa MA Revill A Penny B Newman JH Learmonth ID
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Introduction: Correct prosthesis alignment and joint line reproduction in total knee replacement (TKR) is vital for a successful clinical outcome. It is acknowledged that the ideal coronal alignment of the knee following TKR should be between 4–10 degrees of valgus. A neutral or varus knee is associated with a higher failure rate. Previous studies have shown that ideal alignment is achieved in only around two-thirds of cases.

Joint line elevation > 8mm has been associated with inferior clinical outcome, and depression associated with retropatellar pain and increased risk of patella subluxation.

Recently, modifications have been made to the Kine-max-Plus Total Knee System instrumentation, theoretically providing better internal fixation to prevent a varus cut and a 12 mm measured resection from the “normal” tibial plateau. This study aims to examine whether these changes result in an improvement in alignment, and a more reliable restoration of joint line.

Materials and Methods: Two consecutive series, each of 75 patients who had undergone TKR using either the old (Group A) or the new (Group B) instrumentation were included in the study. Antero-posterior and lateral preoperative and postoperative knee radiographs were assessed using the American knee society radiographic analysis for prosthesis postionoing by 2 independent observers. The Tibial and Femoral Component Angles in the coronal plane (cTCA and cFCA) and in the sagittal plane (sTCA and sFCA) were measured, as was the change in joint line height.

Conclusion: Our results suggest that use of the new instrumentation is associated with better restoration of joint line, and is more effective in preventing implantation of the tibial component in varus. These figures relating to a modern instrumentation system provide a yardstick against which computer assisted and robotic surgery can be judged. Long-term follow-up will be required to assess the clinical significance of these results.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 251 - 251
1 May 2006
Nicol S Howard M Newman J
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Introduction: Progressive symptomatic tibiofemoral arthritis following PFJR is an important cause of failure. This study is designed to quantify radiologically the degree of tibiofemoral disease progression in patients who have undergone PFJR in our institution.

Patients and Methods: A prospective series of 102 consecutive Avon PFJRs in 78 patients with a minimum follow-up of five years was analysed.

Available AP weight bearing radiographs of the knee taken at 8 months and 5 years postoperatively were examined in a random order twice by each of two surgeons who were blinded to the patient details and length of follow up. The severity of arthritis was graded using the classifications of Ahlback and Altman, giving a measure of arthritis progression.

Results and Discussion: Arthritis was seen to progress in 8.5–17% of medial and 11–17% of lateral compartments after PFJR. Statistically significant progression was demonstrated using the Altman but not the less sensitive Ahlback scoring system, suggesting that the former should be used in scoring the tibiofemoral joint prior to PFJR. Of those patients who had a preoperative tibiofemoral Altman score of zero, 87% showed no radiological evidence of disease progression at minimum 5 year follow up, suggesting that these are the ideal candidates for PFJR.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 108 - 108
1 Mar 2006
Hassaballa M Aueng J Hardy J Newman J Learmonth I
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Aim: The Low Contact Stress (LCS) Total Knee Replacements (TKR) is a well-established mobile bearing prosthesis with more than 25 year experience, while the Kinemax Plus is a well established fixed bearing prosthesis. We examined whether reproducing the joint line height to within 5 mm of the pre-operative joint line height had any impact on the clinical outcome in the two different types of Total Knee Replacements.

Method: 48 consecutive LCS knee replacements with a minimum of 2 years follow up had their pre and postoperative joint line (using Figgie’s method) and range of movement (ROM) measured. We used the Oxford Knee Score as a clinical outcome measurement tool.

A cohort group of 53 CR Kinemax plus TKR from the Bristol Knee group was matched for age and sex. They had the same parameters measured.

Results: Accurate joint line restoration was achieved significantly more frequently (P< 0.05) in the Kinemax group. Better post-operative ROM also occurred in the Kinemax group than the LCS, p = 0.03 and the former produced a bigger gain in ROM p < 0.01. However, no difference in the Oxford Knee Score existed between the two prostheses, p = 0.28.

Joint line: elevation K+ LCS

0–2 mm (16/48) = 33% (26/53) = 49% 2–5 mm (14/48) = 29% (14/53) = 26%> 5 mm (18/48) = 38% (12/53) = 25%

There was no significant difference in the ROM or Oxford Knee Score when the joint line was not elevated versus elevated for each prosthesis. However, there was suggestion that the ROM in LCS might be more sensitive to joint line changes, although this was not significant.

ROM

K+ LCS

Normal joint line 116° 105°

Elevated joint line 108° 101°

Conclusion: Accurate joint line restoration could not be shown to correlate with either improved ROM or Oxford knee score; probably because of the small mount of elevation encountered and the small study size. There was a significantly greater post-operative increase in ROM with the Kinemax Plus relative to the LCS, and a significantly closer restoration of the joint line with the Kinemax Plus, both with respect to the actual measurement and with respect to the proportion of cases in which the joint line was accurately reproduced. This is surprising since in most K+ cases additional distal femur had been resected to avoid a tight knee. While in the LCS group special efforts had been made to achieve accurate restoration of the joint level.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 173 - 174
1 Mar 2006
Ridgeway S Bhatnagar P Kharendesh P Gibbs J Newman K Khaleel A Elliott D
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Aim: To describe a radiographic biomechanical classification of tibial plateau fractures which dictates treatment. To compare the intra- and interobserver reliability and reproducibility of this, the Chertsey (C1-3) classification, and the Schatzker (SK1-6) classification.

Method: This classification system has been used at this institution for 8 years by the orthopaedic trauma consultants and consists of C1 – valgus fractures, C2 – Varus fractures and C3 axial fractures. Our treatment regime is based on this classification and results presented in a sperate study. These consultants were excluded from the study on reliability and reproducibility. 2 Orthopaedic consultants, 2 orthopaedic registrars and 2 radiologists were selected randomly to classify 30 sets of AP and Lateral radiographs, of randomly selected patients treated in this institution with tibial plateau fractures, consisting of 9 SK1-3/C1, 8 SK4/C2 and 13 SK5,6/C3 fractures, and again with the same radiographs in a random order 1 month later. Radiographs of fractures treated conservatively were excluded. Statistical analysis included Kappa concordance according to Landis and Koch, and the Mann-Whitney U test.

Results: The Schatzker system was only moderately reliable (K=0.66), and the Chertsey classification system significantly more reliable (K=0.82) (p=0.03) with regards to interobserver reliability. Excellent reproducibility (intra-observer reliability) was seen amongst all observers. The consultant orthopaedic surgeons were significantly more reliable than the radiologists, but not the orthopaedic registrars. No particular fracture type in any classification proved to be significantly more difficult to classify.

Conclusion: We present a classification used in our institution based on plain radiographs, which depicts investigations and treatment. The Chertsey classification is significantly more reliable between observers than the Schatzker classification and is reproducible.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 100 - 100
1 Mar 2006
Newman J Ackroyd C Evans R Gleeson R Webb J
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Introduction Unicompartmental Knee Replacement (UKR) has now become an accepted and widely used treatment for unicompartmental arthritis. Our unit has performed over 1000 UKRs in the past 22 years. The optimal mechanical design of the implant has yet to be determined.

Methods After gaining ethical approval a prospective randomised trial was commenced in 1999 to compare the 2–5 year results of a fixed bearing with a mobile bearing prosthesis. 104 knees in 91 patients underwent a UKR, the mean age of the group was 65 years and a mean weight of 80kg. 57 had a St Georg Sled fixed bearing prosthesis and 47 an unconstrained mobile bearing Oxford UKR. All were prospectively reviewed using the Oxford and Bristol Knee Scores.

Results All 104 knees have been reviewed at 2 years, with none lost to follow-up. 3 patients in the Oxford group suffered a dislocated meniscus and a further 4 required revision, as well as 3 in the St Georg Sled group. The overall function of the 2 groups was the same, but the Oxford mobile bearing group had significantly more persistent pain (p=0.013).

Conclusion The results in both groups were less satisfactory than previous series from this unit probably due to the efforts being made to use minimal incision. However the early complication rate was higher with the mobile bearing devise. This must be balanced against the possible better long-term survival.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 106 - 107
1 Mar 2006
Patel R Stygall J Harrington J Newman S Haddad F
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Aims: To assay the intraoperative cerebral microemboli load during primary total knee arthroplasty(TKA) using transcranial Doppler ultrasound. A battery of ten neuropsychiatric tests were carried out pre and post operatively to examine the change in cognitive outcome. The relationship between emboli load and neuropsychiatric outcome was examined.

Methods: Patients undergoing primary TKA, with no history of stroke, TIA, ongoing CNS disease or alcoholism included. Pre (baseline) and post operative (6 weeks and 6 months) neuropsychiatric tests performed. Scores were recorded as “z change” scores compared with baseline. All operations were carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli load recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis.

Results: 50 TKA patients were studied. Cerebral microembolisation occurred in 63% of TKA patients. Mean microembolic load for TKA patients was 3.83 (range=0–57).

There was no significant change in neuropsychiatric outcome from baseline in these patients at 6 weeks or 6 months. Those patients that experienced cerebral microembolisation did not significantly differ in neuropsychiatric outcome from those that did not.

Conclusion: Intraoperative cerebral microembolisation occurs in almost half of patients during knee arthroplasty. Emboli loads are low and do not appear to cause early or late changes in neuropsychiatric outcome.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 110 - 110
1 Mar 2006
Ackroyd C Newman J Eldridge J
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Introduction: Isolated patello-femoral arthritis occurs in up to 10% of patients suffering osteoarthritis of the knee. Reports of patello-femoral replacements have given indifferent results. We report our experience of 350 cases of the Avon Arthroplasty.

Method: In 1994 after experience with the Lubinus prosthesis which had a 50% failure rate at eight years, we defined the design criteria for a new prosthesis. Since September 1996, 350 knees have been treated with this design. Prospective review was undertaken and 150 knees have reached 2 years and 80 knees are at five years with 10 knees at eight years. The outcome was assessed using pain scores, Bartlett’s patella score and the Oxford knee score.

Results: The patients recovered function rapidly and 20 cases (6%) suffered early complications which resolved. The median pain score improved from 15/40 points to 38 at five years. The movement increased from 114 to 120 at five years. The Bartlett patella score improved from 11/30 points to 25 at five years. The Oxford knee score improved from 19/48 points to 40 points at five years.

The functional results are similar or better than those of a total knee replacement. Fourteen patients developed mal-alignment (4%) two of which required distal realignment. There have been no cases of deep infection, fracture, wear or loosening. Twenty seven knees (7%) developed evidence of disease progression, twenty two of which (6%) have required revision to a total knee replacement. Nineteen patients (5%) complained of some persistent anterior knee pain of uncertain cause.

Conclusions: Results to date show a large improvement in pain and function and this improved design has reduced the problems of mal-alignment and polythene wear. There is a low complication rate and an excellent range of movement. Disease progression remains a problem which is not predictable. This type of prosthesis offers an alternative to total knee replacement in this small group of patients with isolated patello-femoral disease with a low morbidity.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 80 - 81
1 Mar 2006
Pollard T Newman J Barlow N Price J Willett K
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Introduction: Proximal femoral fracture (PFF) is the leading cause of Trauma admission. Deep surgical wound infection occurs in approximately 3% of these patients. The purpose of this study was to assess the cost of deep infection to the patient, in terms of mortality and social consequences, and to the National Health Service, in terms of financial burden.

Methods: 61 consecutive patients (51 females, 10 males) treated for PFF, complicated with deep surgical wound infection over a seven-year period are presented. A control group consisting of 122 patients, without infection, were individually case matched (2:1) for factors that affect outcome after PFF (age, sex, ASA grade, fracture type, operation, and pre-fracture residence, social dependence, and mobility). Outcomes included length of admission (Trauma unit, rehabilitation bed, community hospital), number of operations, antibiotic administration and outpatient treatment, final destination, and mortality at one, three, and six months. A total cost of treatment was obtained from this data and supplied finance department figures.

Results: MRSA was responsible for 31 cases. Infected cases required an average of two wound debridements. 16 patients had a Girdlestones procedure of whom two were subsequently revised to total hip replacement. For all patients, the average Trauma unit admission was 58 days in the infected cases, with a further 40 days spent in rehabilitation or community beds, versus 16 days and 27 days respectively in the controls (p < 0.001). 34% of infected cases died before discharge versus 15% of controls (p = 0.004). For the patients surviving to discharge, the mean total hospital stay was 124 days for the infected cases versus 45 days in the controls (p < 0.001). A higher proportion of the survivors in the control group returned to their original residence compared to the infected survivors (p = 0.002). The mortality rates in the infected group were 15% at 1 month, 31% at 3 months, and 38% at six months, versus 9%, 20%, and 25% respectively in the control group (p = 0.36, 0.12, 0.12). The median cost of treatment per infected case was 23960 versus 7390 per control case.

Conclusions: Deep surgical wound infection after proximal femoral fracture is a devastating complication for both the patient and the NHS. It is associated with a higher in-patient mortality, and fewer survivors return to their pre-fracture residence. Hospital stay is greatly increased and survivors spend 4 months on average in hospital. Additional costs are huge and are incurred at all levels. The extra financial cost of treating a single infected case would fund the treatment of two non-infected cases. These costs should be considered when allocating funds and beds to Trauma services, in addition to ensuring measures known to minimise infection rates are in place.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 104 - 104
1 Mar 2006
Aravindan S Prem H Newman-Sanders A Mowbray
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Purpose of the study: To develop a new treatment algorithm for patients with chronic anterior knee pain based on kinematic patella tracking MR imaging.

Methods and Results: Patients with anterior knee pain of more than one year duration and not responding to non-operative treatment, underwent kinematic MRI study. The provocative test was performed with the conventional MRI scanner and the patient extending the knee against resistance, the resistance provided by inflated beach ball. A retrospective analysis was done of first seventy patients, who had undergone this scanning technique.

On the imaging films, four measurements were made. They were patella subluxation, tilt, cartilage thickness and the Tibial Tubercle Trochlear distance (TTD). Patellar subluxation was classified as mild, moderate and severe. We found that a Tibial Tubercle Trochlea distance of 18mm had a specifity of 100% and a sensitivity of 89% for severe maltracking.

Conclusion: Kinematic MR Imaging is a useful investigation before considering operative treatment for patients with chronic anterior knee pain. Based on our study, we conclude that those patients with moderate lateral maltracking with a TTD< 18 mm should be offered lateral release and those with severe maltracking and TTD> 18mm should have a tibial tubercle transfer, in addition to lateral release.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 99 - 100
1 Mar 2006
Newman J Ackroyd C Evans R
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Introduction. There has been a recent major increase in the use of unicompartmental knee replacement (UKR) but few studies exist comparing its long term efficiency with total knee replacement (TKR)

Method. Ethical approval was obtained.

Between 1989 and 1992 a randomised prospective study was undertaken in which 102 cases adjudged suitable for UKR were allocated to receive either a St Georg Sled UKR or a Kinematic Modular TKR. Both cohorts had a median age of 68 and a similar sex distribution and preoperative knee score. Regular follow up has been maintained. As reported the early results favoured UKR. All cases have now been assessed after a minimum of 10 years using modified WOMAC, Oxford and Bristol Knee Scores (BKS) as well as radiographs.

Results. 28 cases had died with their knees known to be intact, 2 cases were untraceable. 33 knees in each group were reviewed. 3 in each group had been revised, no impending failures were identified on the radiographs.

At 10 years the UKR group had better Oxford and WOMAC scores as well as significantly more excellent results (19:14) and fewer fair and poor results on the BKS. Both groups averaged over 105′ of flexion but 61% of the UKR and only 15% of the TKR group had 120′ or more of flexion.

Conclusion. The faster rehabilitation and better early results with UKR are maintained for 10 years with few failures occurring. The average BKS of the UKR group only fell from 91 to 88 between 5 and 10 years suggesting minimal evidence of functional deterioration in either the prosthesis or the remainder of the joint.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 344 - 344
1 Sep 2005
Hollinghurst D Stoney J Ward T Robinson B Price A Gill H Beard D Dodd C Newman J Ackroyd C Murray D
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Introduction and Aims: Single compartmental replacement procedures are increasingly preferred over total knee replacement (TKR) for single compartment osteoarthritis of the knee joint. Theoretically, reduced disruption of the native joint should produce more normal kinematics. This study aimed to describe and compare the sagittal plane kinematics of four different, commonly used devices.

Method: Four groups of patients who had undergone successful single compartment replacement at least two years previously were recruited. Fifteen following Oxford medial UKA, 12 following medial St Georg Sled UKA, five following Oxford lateral UKA, and 12 following Avon PFJ replacement. Patients performed flexion/extension against gravity, and a step-up during video fluoroscopy. The Patellar Tendon Angle (PTA), the angle between the long axis of the tibia and the patella tendon, was obtained as a function of knee flexion. This relationship provides indication of sagittal movement between femur and tibia through range and has been validated as a reliable measure of joint kinematics.

Results: The kinematic profile for each group was compared to that of the profile for 12 normal and 30 TKR (AGC) knees. All three tibiofemoral devices produced knee kinematics similar to the normal knee. The PTA was found to have a linear relationship to flexion angle, decreasing with increasing knee flexion angle. No such linear relationship exists for the TKR joint, which display abnormal kinematics. The PF device also reflected similar trends to that for normal knees except that the PTA was moderately increased throughout the entire range of flexion (three degrees).

Conclusion: In contrast to TKR, all single compartmental knee replacements provided kinematics similar to the normal joint. The kinematic pattern of the PFJ replacement may be of most interest as the observed increase in PTA through range could influence patello-femoral contact forces


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 343 - 344
1 Sep 2005
Ashraf T Newman J Ackroyd C
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Introduction: Uni-compartmental Knee Replacement (UKR) has now become an accepted and widely used treatment for uni-compartmental arthritis. Our unit has performed over 1000 UKRs in the past 22 years. The optimal mechanical design of the implant has yet to be determined.

Method: A prospective trial was commenced in 1999 to compare the short-term results of a fixed bearing with a mobile bearing prosthesis. One hundred and three knees in 95 patients underwent a UKR. Fifty-three had a St Georg Sled fixed bearing prosthesis and 50 had unconstrained mobile bearing Oxford UKR. All were prospectively reviewed using the Oxford and Bristol Knee Scores.

Results: Eighty-four knees have been reviewed at two years with one lost to follow-up. One fixed (2%) and six mobile (12%) bearing knees had been revised. Three fixed bearing and eight mobile bearing knees were dissatisfied because of stiffness or persistent pain and seven mobile bearing knees had undergone further minor procedures, usually for dislocation. At two years, the Bristol and Oxford knee scores for fixed bearing were better than the mobile bearing knees at 90:83 /100 and 38:33 /48 respectively.

Conclusion: There were more early complications in the mobile bearing UKR group, but the functional results were slightly better than in the fixed bearing knees.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 343 - 343
1 Sep 2005
Ackroyd C Newman J Evans R
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Introduction and Aims: There has recently been an increase in the use of uni-compartmental knee replacement (UKR), but there are few studies comparing its long-term efficacy and survival with total knee replacement (TKR). We reported the five-year results of a randomised trial which showed that uni-compartmental replacement had a faster rehabilitation and better functional results than total replacement. We now report the 10-year results.

Method: After obtaining ethical approval, between 1989 and 1992, 102 cases judged suitable for UKR were randomly allocated to receive either a St Georg Sled UKR or a Kinematic Modular TKR. Both cohorts had a median age of 68 and a similar sex distribution and pre-operative knee scores. Regular follow-up has been maintained. All cases have now been assessed after a minimum of 10 years using modified the WOMAC, Pain, Oxford and Bristol Knee (BSK) scoring systems as well as radiographs.

Results: At 10 years, 29 cases had died with their knees known to be intact, two totals cases were untraceable. Thirty-two uni`s, and 34 totals were available for review. Three uni`s (6%) and two totals (4%) had been revised; there was one impending total failure on the radiographs.

The UKR group had better scores with Oxford: 38 v 34 /48 and WOMAC: 17 v 21 /60 and more excellent results (19 v 14) and fewer fair and poor results on the BKS (4 v 6). The range of movement improved in UKA`s from 107 degrees to 117 degrees, whereas the range decreased in TRK`s from 107 degrees to 104 degrees. Sixty-one percent of the UKR and only 16% of the TKR group had more than 120 degrees of flexion.

Conclusion: The St Georg Uni-compartmental arthroplasty continues to function well at 10 years, with better functional scores and a better range of movement than the Kinematic Total arthroplasty. There were similar failures in both groups.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 338 - 338
1 Sep 2005
Ackroyd C Newman J
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Introduction: Isolated patello-femoral arthritis occurs in up to 10% of patients suffering osteoarthritis of the knee. Reports of patello-femoral replacements have given indifferent results so we wish to report our experience of 326 cases using two different protheses.

Method: In 1989 we started a prospective series of the Lubinus prosthesis. The results of 76 cases at eight years showed a 50% failure rate. The main reasons for failure were malalignment, wear and disease progression. The Avon patello-femoral arthroplasty was designed to solve some of these problems.

Since September 1996, 250 knees have been treated. Prospective review was undertaken and 120 knees have reached two years and 40 are at five years. The outcome was assessed using pain scores, Bartlett’s patella score and the Oxford knee score.

Results: The median pain score improved from 15/40 points to 35 at five years. The movement increased from 114 to 120 degrees at five years. The Bartlett patella score improved from 10/30 points to 26 at five years. The Oxford knee score improved from 19/48 points to 40 points at five years.

The functional results are similar to those of a total knee replacement. Two patients developed malalignment (1%) one of which required distal soft tissue realignment. There have been no cases of deep infection, fracture, wear or loosening. Sixteen knees (6%) developed evidence of disease progression, 14 of which (6%) have required revision to a total knee replacement.

Conclusions: Results to date suggest that this improved design has reduced the problems of malalignment and early wear. There is a low complication rate and an excellent range of movement. Disease progression remains a problem that is not predictable. This type of prosthesis offers an alternative to total knee replacement in this small group of patients with isolated patello-femoral disease with a lower morbidity.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 339 - 340
1 Sep 2005
Newman J Ackroyd C Bedi G
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Introduction and Aims: Our experience with over 200 cases of Avon patellofemoral replacement (PFR) in the elderly with severe arthritis has been satisfactory, so we have extended the indications to younger patients with severe symptoms and various pathologies.

Method: Sixty-six knees in 53 patients (10M: 46F) under the age of 55 years (average 47 years) have been treated with an AVON PFR for the following conditions:

PATHOLOGY NUMBER of Knees

Isolated lateral facet OA 34

Failed realignment 12

Persistent subluxation/dislocation 5

Trochlear dysplasia 5

Pure chondral disease 3

Failed carbon fibre implant 3

Post-patellectomy instability 3

Post-traumatic pain 1

All patients were recorded prospectively and have been regularly reviewed using the modified Oxford, Bartlett & Bristol Knee scoring systems. The mean follow-up of the group is 24 months.

Results: No patient has been lost to follow-up, all knee scores improved substantially.

Most of the patients retained their range of flexion and the mean range of movement increased from 112 to 122 degrees. Patients with persistent subluxation were the most dramatically improved. There have been no cases of deep infection, loosening or wear.

Conclusion: Avon PFR provides a reliable short-term solution to some of the more difficult and disabling problems of the patello-femoral joint as long as demonstrable pathology is present.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 340 - 341
1 Sep 2005
Hassaballa M Porteous A Newman J
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Introduction and Aims: Kneeling is an important function of the knee joint but little information is available on ability to kneel after different types of knee arthroplasty. We aimed to assess patients’ kneeling ability pre- and post-operatively after uni-compartmental, patellofemoral and total knee arthroplasty (UKR, PFR, TKR) and to objectively examine: kneeling ability, factors that affect it and whether this ability differed from the patient’s perception.

Method: In 253 knee arthroplasty cases, we prospectively analysed the ability to kneel pre-operatively, and post-operatively at one and two years using the relevant section of the Oxford Knee Score questionnaire. One hundred and twenty-two post-operative patients (38 TKR, 53 UKR, 31 PFR) were then examined to assess their actual kneeling ability.

Results: Patients’ perception of their kneeling ability prior to surgery was poor in all three groups (mean score 0.7 out of 4) and improved in all groups after surgery (mean score at two years 1.46 out of 4). Perceived kneeling ability was best in UKR and worst in PFR (P< 0.001). Perceived kneeling ability improved most in the first year post-operatively, but continued to improve between one and two years although the final kneeling function was still not good. When examined, only 37% of patients thought they could kneel, whereas 81% were actually able to kneel (P< 0.001). Ability to kneel was significantly better than perceived ability for all prosthesis types (P< 0.001). Kneeling ability was better in men and associated with an increased range of movement (P< 0.001).

Conclusion: Kneeling ability is poor prior to knee arthroplasty and improves up to two years post-operatively, though it is still perceived to be poor, but can be improved with rehabilitation. UKR gave better kneeling ability than PFR or TKR. Patient-centred questionnaires do not accurately document kneeling ability after knee arthroplasty.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 157 - 157
1 Apr 2005
Hassaballa M Newman J
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Purpose This study was carried out to compare the alteration in skin sensation following midline, medial and short medial incisions for knee replacement.

Method 88 patients with 102 knees were examined for altered skin sensation over the front of the knee, all were at least 18 months from their knee replacement. Twenty-one knees had a medial incision, 38 a midline incision and 43 a short medial incision for UKR.

A scale of −2 to +2 was used to measure different degrees of skin hypo or hyperaesthia. A purpose-designed grid, designed to fit different knee sizes, was used to record sensations. A computer programme was created to record all patients’ data including the length and shape of the incision in relation to anatomical landmarks.

A parallel histological study was carried out on 12 skin specimens taken from the 2 standard incisions. The specimens were prepared and stained for nerve endings. The number of nerve endings in each incision was calculated.

Results The average length for the medial incision was 17 cm with an average post-operative time of 3.37 yrs and skin numbness of 87.78 cm square.

The midline incision average length was 17.85 cm with an average post-operative time of 4.7 yrs and a numb area of 73.7 cm square.

The short medial incision used for UKR averaged to be 9 cm in length with an average post operative time of 3.9 yrs and an area of numbness of 48.1 cm square.

Histologically less cutaneous nerve endings were seen in specimens from midline incisions than medial incisions.

Discussion The midline line incision seems to produce less dermal parasthesia than the medial incision, this probably relates to both the wound position and the density of nerve endings. The length of the incision correlated with the area of numbness when comparing the short and long medial incisions.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 153 - 153
1 Apr 2005
Utting MR Newman JH
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Purpose: To assess the outcome of customised hinged knee replacements when used to salvage catastrophically failed knee replacements in elderly patients.

Methods: Since 1993, 30 of the 280 (10.7%) revision knee replacements at the Avon Orthopaedic Centre, Bristol have used Endo customised hinged knee pros-theses (21 rotating, 9 fixed) for salvage of limb threatening situations in elderly patients. All were prospectively recorded and regularly reviewed. The average age was 75 years with a predominance of females. Surgical indications were 22 periprosthetic fractures (with or without aseptic loosening), 5 massive aseptic osteolyses, and 3 deep infections.

Results: The mean length of postoperative hospital stay was just 14.6 days and all patients were discharged walking with aids. At follow up (mean 3.0 years, range 0.5–9.3 years) 9 patients had died with their prostheses in situ and functioning. 2 had undergone amputation for recurrent sepsis and 2 had received further surgery for septic problems. 2 patients required further surgery for prosthetic disarticulation and one patient had successful on table vascular repair. 25 patients had mid or long term follow up. Their mean American Knee Scores (AKS) were 69.8 for knee and 35.6 for function (maximum 100), with a mean total knee flexion of 83 degrees. Mean Oxford knee scores (OKS) and WOMAC scores (both scored between 12 and 60 with low score indicating less difficulties) were 34.0 and 30.5 respectively.

Conclusions: Customised hinge revision knee replacements gave extremely rapid rehabilitation and hospital discharge which justified the high prosthetic cost. Complications were high but at mid and long-term review, no prostheses had failed from an aseptic cause and most of the knees of this challenging group were providing both stability and flex


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 152 - 152
1 Apr 2005
Aravindan S Prem H Newman-Sanders A Mowbray M
Full Access

Purpose of the study: To develop a new treatment algorithm for patients with chronic anterior knee pain based on kinematic patella tracking MR imaging.

Methods and Results: Patients with anterior knee pain of more than one year duration and not responding to non-operative treatment, underwent kinematic MRI study. The provocative test was performed with the conventional MRI scanner and the patient extending the knee against resistance, the resistance provided by inflated beach ball. A retrospective analysis was done of first seventy patients, who had undergone this scanning technique.

On the imaging films, four measurements were made. They were patella subluxation, tilt, cartilage thickness and the Tibial Tubercle Trochlear distance (TTD). Patellar subluxation was classified as mild, moderate and severe. We found that a Tibial Tubercle Trochlea distance of 18mm had a specifity of 100% and a sensitivity of 89% for severe maltracking.

Conclusion: Kinematic MR Imaging is a useful investigation before considering operative treatment for patients with chronic anterior knee pain. Based on our study, we conclude that those patients with moderate lateral maltracking with a TTD< 18 mm should be offered lateral release and those with severe maltracking and TTD> 18mm should have a tibial tubercle transfer, in addition to lateral release.


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 4 | Pages 561 - 565
1 May 2004
Sehat KR Evans RL Newman JH

Following total hip arthroplasty (THA) and total knee arthroplasty (TKR) only the ‘visible’ measured blood loss is usually known. This underestimates the ‘true’ total loss, as some loss is ‘hidden’. Correct management of blood loss should take hidden loss into account.

We studied 101 THAs and 101 TKAs (with re-infusion of drained blood). Following THA, the mean total loss was 1510 ml and the hidden loss 471 ml (26%). Following TKA, the mean total loss was 1498 ml. The hidden loss was 765 ml (49%). Obesity made no difference with either operation.

THA involves a small hidden loss, the total loss being 1.3 times that measured. However, following TKA, there may be substantial hidden blood loss due to bleeding into the tissues and residual blood in the joint. The true total loss can be determined by doubling the measured loss.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 446 - 446
1 Apr 2004
Porteous A Hassaballa M Newman J
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Aim: The aim of this study was to evaluate the functional results and ease of performing revision surgery after a primary unicompartmental arthroplasty versus primary total knee arthroplasty.

Method: 114 revision TKRs had data collected prospectively as part of our unit’s Knee Database. 45 were revisions of UKR’s and 79 revisions of TKR’s. This data included Bristol Knee Scores (BKS), reason for revision, use of implant augments and bone graft. Measurements were also made of the ability to restore joint-line after revision.

Results: In both groups there was a significant improvement in BKS post-operatively. In the UKR group the commonest reason for revision was progression of disease, while in the TKR group it was aseptic loosening. Bone graft was required in significantly fewer UKR cases (20% vs 40%, P< 0.05). Distal femoral augments were used in 45% of the TKR revisions but in none of the revisions from UKR. The joint line was elevated in a significantly higher proportion of revision from TKR cases versus revision from UKR cases (P< 0.001). Revisions from UKR had higher Total BKS and Functional BKS score than revisions from TKR.

Conclusions: Revision TKR after a primary UKR requires less bone graft, fewer augments, restores the joint line more frequently and gives improved functional results over revisions after primary TKR.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 441 - 441
1 Apr 2004
Ackroyd CE Newman JH Bedi G
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Purpose A new design of patello-femoral arthroplasty has been used to treat patients under 55 years suffering severe symptoms from chondral and early arthritic disease of the patello-femoral joint.

Materials and Methods and Results Fifty-two patello-femoral arthroplasties were performed in 45 patients under the age of fifty-five years when other treatments had failed. The average age was 48 years (range 36–54 years). Thirty-seven cases had undergone previous surgery for a variety of conditions, and the causes of the disorders were analysed. Results were assessed using pain scores and Bartlett’s and Oxford functional scores. 35 cases were reviewed at 8 months and 22 cases at two years. The median pain score improved from 10/40 points to 35 at two years. The Bartlett score increased from 10/30 points to 27 and the Oxford score from 19/48 points to 35 at two years. The range of movement increased from 114° to 121°. There have been no cases of deep infection, loosening, wear or instability. Disease progression, a potential risk has occurred in one case.

Conclusions This prosthesis offers a solution in younger patients with disabling symptoms of isolated early patello-femoral disease who have not responded to conservative surgical management.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 393 - 393
1 Apr 2004
Newman MA
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The study was designed to compare the clinical performance of an Alumina ceramic acetabular bearing to that of a polyethylene bearing in a cementless hip couple.

The study group consisted of 15 surgeons who performed 308 total hip replacements (297 patients) between January 29, 1998 and February 1, 2000. All patients received a porous coated cementless titanium stem with an Alumina ceramic 28 mm or 32 mm head. Patients were randomized to receive a porous titanium acetabular shell with either a polyethylene or Alumina cup liner. There were 164 Alumina cups and 144 polyethylene cups. The mean age was 57.3 years and consisted of 50% males and 50% females. The preoperative diagnoses were: osteoarthritis 69.8%, avascular necrosis 19.5 %, post traumatic arthritis 2.9 %, inflammatory arthritis 3.9% and other 3.9%. The mean follow up was 12 months. The longest follow up was 38 months.

The Harris Hip Score was good and excellent in 86% of the control patients and 87% of the study patients. There has been 100% follow up and survivorship.

There were two reoperations for recurrent dislocations in each group. There were no Alumina component fractures, no progressive radiolucencies and no evidence of rapid wear.

In the short term follow-up between 12 and 38 months, there do not appear to be any differences between the patients with a bearing couple consisting of Alumina on plastic with those consisting of Alumina on Alumina. There have been no catastrophic failures of the ceramic components. The Alumina/Alumina bearing couple for total hip arthroplasty appears to be an excellent alternative bearing, providing the advantage of improved long term wear and a reduced incidence of polyethylene induced osteolysis.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 337 - 337
1 Mar 2004
Mo H Porteous A Newman J
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Aim: To assess the functional results of revision TKR with the PFC/TC3 system, and to correlate this with the reasons for revision and restoration of joint height. Method: 153 patients underwent revision TKR using the PFC/TC3 system. Data was prospectively collected (using the Bristol Knee Score) pre-operatively and at a mean of 4.2 years post-revision. 43 revisions were for infection and 81 revisions were for aseptic loosening. Measurements of the joint height were made pre and post-operatively using FiggieÔs method and were divided into 3 groups: lower by more than 5mm, restored and elevated more than 5mm. Use of distal augments and polyethylene thickness were recorded. Results: The mean pre-op function score was 12 and post-operatively was 19 for the infection group and 20 for the aseptic loosening group. Revision after initial UKR gave a mean score of 21, while revision after TKR gave a mean score of 18 (max 27). Knees in which the joint line was elevated by more than 5 mm had a mean score of 17 while those where the joint line was restored had a mean score of 19. Recent increasing use of distal augments improved the joint line and results. Conclusion: revision using the PFC/TC3 system produced acceptable medium term functional results and good survival. Better restoration of joint line and functional results were achieved by distal femoral rather than proximal tibial augmentation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 282 - 282
1 Mar 2004
Karnezis I Athanasiou A Newman J
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Aims: To investigate whether normal statistical ßuctuation in the incidence of early complications of primary Knee Arthroplasty (TKA) follows the laws of statistical probability and can thus be amenable to analysis by standard Statistical Quality Control (SQC) methods. The þnal objective is to apply such techniques to distinguish random ßuctuation from real (undetected by traditional p value statistical methods) increase in the incidence of early complications in primary joint Arthroplasty. Methods: We employed statistical quality control charts (X-bar, p, c, u and np) to analyse postoperative complications and length of stay in 1,196 consecutive primary TKAs performed over a 20-quarter time period (October 1995 to September 2000). For all analyses (Minitab 12.1 software) the standard practice of employing ± 3 standard deviation upper and lower control limits and generally accepted criteria for determining the presence or absence of statistical control were used. Results: Deep infection, major thromboembolic incident, total number of complications per case and total number of complicated cases appeared to be in stable statistical control and followed the laws of statistical ßuctuation throughout the entire study period. However, patella mal-tracking, persistent knee stiffness, postoperative length of stay and total number of postoperative complications showed an (undetected by conventional postoperative audit methods) lack of control at various time periods with subsequent return to the statistically-controlled range. Conclusions: SQC methods may be employed in the audit of postoperative events in TKA and can be a valuable tool in continuous assessment of the statistical variability of postoperative complications, with the aim of reducing the variability and improving clinical outcome Arthritic knee imaging


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 232 - 232
1 Mar 2004
Patel R Stygall J Harrington J Newman S Haddad F
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Aims: To compare the intraoperative cerebral microemboli load between primary total hip (THA) and knee arthroplsty (TKA) using transcranial Doppler ultrasound and to investigate whether a patent foramen ovale influences cerebral embolic load in general. The timing of the microemboli will be related to certain surgical activities to determine if a specific relationship exists. Methods: Patients undergoing primary TKA or THA, with no history of stroke, TIA, ongoing CNS disease or alcoholism included. All operations carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli load recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis. Patent foramen ovale detection performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre technique and TCD. Timing of specific surgical steps recorded for each operation and emboli load calculated for that period. Results: 20 THA and 20 TKA patients were studied. Cerebral microembolisation occurred in 50% of THA and 40% of TKA patients. Total microembolic load for THA patients was 137 (range=0–83) and 50 (range=0–21) for TKA patients. Prevalence of PFO in the THA group was 35%, and 20% in the TKA group. 57.1% of PFO positive THA patients and 75% of PFO positive TKA patients displayed microemboli. Insertion of the femoral component in THA and release of the tourniquet in TKA were associated with higher cerebral microemboli load. Conclusion: Intraoperative cerebral microembolisation occurs in almost half of patients during hip and knee arthroplasty. Patients who have a PFO appear more likely to be associated with cerebral embolisation. Specific surgical activities are associated with larger embolic loads.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 309 - 309
1 Mar 2004
Ashraf T Newman J Evans R Beard D Ackroyd C
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Introduction: Lateral uni-compartmental knee replacement (UKR) is seldom indicated and remains controversial. It has been considered a technically challenging operation with variable success. Aim: The aim of this paper is to assess the results of unicompartmental knee replacement using a þxed noncongruous prosthesis. Methods: Eighty-eight knees in 79 patients with lateral unicompartmental osteoarthritis treated with a þxed bearing, non-congruous, fully unconstrained prosthesis. (St Georg Sled UKR) over a period of 21 years by different consultants and there trainees. Surgical approach and rehabilitation protocol varied over this period but there was no change in the surgical indications. Results: At a mean follow up of 9 years (range 2 to 21 years). Fifteen knees had revision surgery (9 for progression of arthritis and 6 for component loosening, 4 for implant breakage and 4 for more than one reason). Six patients complained of moderate or severe pain at þnal follow up. Only þve knees were lost to follow up in the 21-year period. Survivorship analysis was performed on the group using revision for any cause as the end point. At ten years the cumulative survival rate was 83% and at 15 years, when ten knees were still at risk, the cumulative survival rate was 74%. Conclusion: Based on our clinical results and survival rate the St Georg Sled UKR can be considered a suitable treatment for isolated lateral compartment osteoarthritis.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 128 - 129
1 Feb 2004
Prem M Aravidan M Mowbray M Newman-Sanders D
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The diagnosis and subsequent treatment of patients with “Anterior Knee Pain” remains a challenge and an enigma at times.

The 4 main parameters, which need to be assessed, are:

Bony anatomy of the PFJ

Cartilage structure within the PFJ

Tracking of the patella with active knee extension

Structure of the soft tissues in the extensor mechanism

While plain radiographs, CT scans and static MRI sans and arthroscopic assessments highlight some of the parameters none of them are comprehensive. The type of MRI scanning used in this study assesses all 4 parameters. The equipment required for resisted quadriceps contraction is inexpensive and readily available.

Material and Methods: 70 patients had dynamic MRI scans done over a period of 2 years. The study consisted of 3 parts:

Radiological diagnosis and grading of subluxation if present.

Clinical scoring of 26 patients who returned the questionnaires. Oxford, Lysholm and Tegner scores were used and correlated with the radiological scores.

Development of a Treatment Algorithm based o the scan results.

Conclusion: The Tibial Tubercle to Trochlear Groove Distance” (TTD) appears to be the single most significant parameter determining patellar tracking. Objective radiological assessment is possible under physiological loading, to differentiate tilt, subluxation and chondromalacia. We have proposed an algorithm for the surgical and non-surgical treatment of anterior knee pain. The pain scores did not show a significant correlation with the grading of subluxation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 78 - 78
1 Jan 2004
Patel RV Stygall J Harrington J Harrison MG Newman S Haddad FS
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Aims: To quantify the intraoperative cerebral microemboli load during primary total hip arthroplasty (THA) using transcranial Doppler ultrasound and to investigate whether a patent foramen ovale influences cerebral embolic load in general. The timing of the microemboli will be related to certain surgical activities to determine if a specific relationship exists.

Methods: Patients undergoing primary THA, with no history of stroke, TIA, ongoing CNS disease or alcoholism were included. All operations were carried out under a standardised general anaesthetic and performed by two consultant orthopaedic surgeons. Microemboli load was recorded, using transcranial Doppler ultrasound (TCD), onto VHS tape for subsequent playback and analysis. Patent foramen ovale detection was performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre technique and TCD. Timing of specific surgical steps was recorded for each operation and emboli load calculated for that period.

Results: 25 THA patients were studied (18 females, 7 males) 16 right and 9 left THA’s were performed. Cerebral microembolisation occurred in 10 patients (40%). Mean microembolic load was 5.52 per patient (range = 0–83). PFO was detected in 8 patients (32%). 37.5% of PFO positive patients displayed cerebral microemboli. However, 41.1% of PFO negative patients also displayed microemboli intraoperatively.

Insertion of the femoral component was associated with generating a larger microembolic load than the other phases of the operation.

Conclusion: Intraoperative cerebral microembolisation occurs in a significant proportion of patients during total hip arthroplasty. The presence of a patent foramen ovale does not appear to influence the incidence microemboli intraoperatively. Specific surgical activities are associated with generating greater embolic loads. These questions will be comprehensively assessed in the larger study currently underway..


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 201 - 201
1 Mar 2003
Newman E
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Between June 1986 and 1993, 208 Protek CLS total hip replacements were inserted in 174 patients. These have been reviewed clinically and radiologically by independent observers at 3 yearly intervals.

One hundred and sixty six hips in 137 patients were available for review 9 to 15.5 years from insertion (mean just over 10.5 years). There has been no significant clinical or radiological change when compared to reviews three and six years ago with regard to the Harris Hip Score and the pain and function components of this. There has also been no change in subsidence, heterotopic ossification or lucencies. There has been no significant difference in results between males or females, nor between other factors such as pre-operative diagnosis, the use of metal or ceramic heads, age at time of operation or length of follow up. The failure rate remains low, less than 4%, i.e. survival rate greater than 96%. The reasons for failure in general do not relate to the fixation of either the acetabular or femoral components.

The results of this long-term follow up of a large group of relatively young patients at time of insertion of arthroplasty remain very satisfactory.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 249 - 249
1 Mar 2003
Bishop T Molloy S Solan M Elliott D Newman K
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Traditionally, immobilisation following achilles tendon rupture has been for 10 to 12 weeks.

We have previously published a series of 71 consecutive repairs with no re-ruptures, using a lateral surgical approach. The latter part of this cohort were immobilised for six weeks instead of 12, with early weight bearing. The lack of any re-ruptures encouraged us to pursue the accelerated rehabilitation.

This study documents a further 34 cases followed prospectively for 6–24 months (mean 15.9 months). All were repaired with a single Kessler-type suture using loop PDS, through a lateral approach. Patients were partial weight-bearing immediately in an Aircast boot with three cork heel wedges. At two-weekly intervals the wedges were reduced, and the boot abandoned after six weeks.

There have been no re-ruptures. Thirty of the 34 patients returned to pre-injury activity levels. All patients were satisfied or very satisfied with the immobilisation device and the accelerated rehabilitation regime. Cost savings were also made through use of a single removable orthosis rather than sequential casts.

We advocate this regimen of careful operative achilles tendon repair and accelerated weight bearing rehabilitation with a removable orthosis.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 203 - 203
1 Mar 2003
Newman E
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The purpose of the study was to review and present a series of early failures of the Miller Galante unicom-partmental knee replacement (UKR). Following several early failures all Miller Galante UKR’s inserted by the author (60 patients, 72 knees) were recalled for clinical and radiological review including assessment using the American Knee Society Score and the Oxford Knee Score. All knees with effusions were aspirated and specimens sent for histological analysis.

There were 22 females and 38 males with a mean age of 67 years. The mean follow up was 3.4 years. Six failures were noted with follow up from 10 months to 4 years. These 6 cases will be discussed in more detail including operative findings at revision and possible reasons for failure.

Early failure of this arthroplasty is unacceptable and caution should be exercised if contemplating using this implant unless more definite causative factors are identified.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 244 - 244
1 Mar 2003
Bishop T Molloy S Solan M Elliott D Newman K
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Traditionally, immobilisation following Achilles tendon rupture has been for 10 to 12 weeks.

We have previously published a series of 71 consecutive repairs with no re-ruptures, using a lateral surgical approach. The latter part of this cohort were immobilised for six weeks instead of 12, with early weight bearing. The lack of any re-ruptures encouraged us to persue the accelerated rehabilitation.

This study documents a further 34 cases followed prospectively for 6–24 months (mean 15.9 months). All were repaired with a single Kessler-type suture using loop PDS, through a lateral approach. Patients were partial weight-bearing immediately in an Aircast boot with three cork heel wedges. At two-weekly intervals the wedges were reduced, and the boot abandoned after six weeks.

There have been no re-ruptures. Thirty of the 34 patients returned to pre-injury activity levels. All patients were satisfied or very satisfied with the immobilisation device and the accelerated rehabilitation regime. Costs savings were also made through use of a single removable orthosis rather than sequential casts.

We advocate this regimen of careful operative achilles tendon repair and accelerated weight bearing rehabilitation with a removable orthosis.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 162 - 163
1 Feb 2003
Ackroyd C Newman J
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Isolated patello-femoral arthritis occurs in up to 10% of patients suffering osteoarthritis of the knee. Previous reports of several different patello-femoral designs have given indifferent results. The Lubinus prosthesis has a reported 50% failure rate at eight years in a study of 76 cases. The main reasons for failure were mal-alignment, wear, impingement and disease progression. The Avon patello-femoral arthroplasty was designed to solve some of these problems.

The first cases were implanted in September 1996 and entered into a prospective review. The outcome was assessed using pain scores, Bartlett’s patella score and the Oxford knee score. To date 207 knees have been treated and 95 knees have reviewed at two to five years. The median pain score improved from 15/40 points to 35 at five years. The movement increased from 114° to 120° at five years. The Bartlett patella score improved from 10/30 points to 26 at five years. The Oxford knee score improved from 19/48 points to 40 points at five years. Two patients developed mal-alignment (1%) one of which required distal soft tissue realignment. There have been no cases of deep infection, fracture, wear or loosening. Fifteen knees (7%) developed evidence of disease progression, twelve of which (6%) have required revision to a total knee replacement. The functional results are similar to those of a total knee replacement.

Results to date suggest that this improved design has all but eliminated the previous problems of mal-alignment and early wear. The functional results are as good as or better than those of a total knee replacement. There is a low complication rate and an excellent range of movement. Disease progression remains a potential problem. This type of prosthesis offers a reasonable alternative to total knee replacement in this small group of patients with isolated, early patello-femoral disease.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 96 - 96
1 Feb 2003
Squires B Newman JH
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The aim of this study was to examine causes of the failed knee arthroplasty.

Since 1980 the Bristol Knee Replacement Registry has prospectively recorded data on 3024 patients. Complete original and 5 year follow up data was available on 999 knees.

The surgery was judged a failure if there was no improvement in the American Knee Society score at 5 years or if there had been a revision within that time.

The prosthesis used was Kinematic in 471 knees, the Medial Unicompartmental Sled in 258 knees, the Kinemax Plus in 134 knees and a variety of other designs.

At 5 years, 79 (7. 9%) either showed no improvement in the American Knee Society score or had been revised. The failure rate was 7% for the Kinematic, 7% for the medial Sled and 5% for the Kinemax Plus. 20% of the less frequently used designs failed.

Five (0. 5%) knee replacements failed because of infection. 22 knees (2. 2%) had significant comorbidity that precluded a satisfactory functional outcome. For 7 knees (0. 7%), the patient exhibited patterns of abnormal illness behaviour that were thought to explain the poor outcome. A further 27 knees (2. 7%) failed because of technical errors either at the time of surgery (13 cases, 1. 3%), or in selecting a prosthesis which failed prematurely (14 cases 1. 4%). No cause for failure could be identified in 12 cases (1. 2%).

The high failure rate amongst infrequently used prosthesis emphasises the need to use established designs. No cause for failure could be identified in 12 cases and 5 were due to infection; such cases are hard to avoid. This study shows the importance of assessing both the overall physical and psychological state of the patient if disappointing results are to be avoided. The most frequent cause of an unsatisfactory outcome was a technical one, which should be avoidable.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 132 - 133
1 Feb 2003
Ackroyd CE Newman JH Elderidge J Webb J
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Isolated patellofemoral arthritis occurs in up to 10% of patients suffering osteoarthritis of the knee. Previous reports of several different patellofemoral designs have given indifferent results. The Lubinus prosthesis has been shown to have a 50% failure rate at eight years in a study of 76 cases. The main reasons for failure were mal-alignment, wear, impingement and disease progression. As a result of these studies, a new prosthesis was designed to solve some of these problems.

The Avon patellofemoral arthroplasty was first implanted in September 1996. The cases have been entered into a prospective review with evaluations at eight months, two years and five years. The outcome was assessed using pain scores, Bartlett’s patella score and the Oxford knee score. To date, 186 knees have been treated; over 100 knees have been reviewed at two years and 20 knees at five years. The main pain score improved from a pre-operative level of 13.5 points out of 40 to 33.5 points at two years and 36 at five years. The mean pre-operative movement was 109° and this increased to 120° at five years. The Bartlett patella score improved from a pre-operative level of 10.5 points out of 30 pre-operatively to 23 points at two years and 25 at five years. The Oxford knee score was 20 points out of 48 pre-operatively and this improved to 35 points at two years and 40 points at five years. One patient developed subluxation, which required distal soft tissue realignment. No other patient has developed problems with alignment or wear. Ten knees have developed evidence of disease progression usually in the medial compartment of which six have required revision to a total knee replacement.

The results to date suggest that this improved design has all but eliminated the previous problems of malalignment and early wear. The functional results are as good or better than those of a total knee replacement. There is a low complication rate and an excellent range of movement. Disease progression remains a potential problem. This type of prosthesis offers a reasonable alternative to total knee replacement in this small group of patients with isolated, early patellofemoral disease.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 33 - 33
1 Jan 2003
Newman J Ackroyd C Kennedy G Dieppe P
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The Bristol Knee Replacement Registry was established in the 1970’s and contains prospectively recorded data on 3024 patients. The present study examines the group of 812 patients for whom complete pre-operative and five year post-operative data is available in order to relate their eventual health status to the pre-operative demographic data and to disease severity. The group comprised 593 women and 219 men who had undergone either Kinematic, Total or Sled unicompartmental knee replacement.

Pre-operatively, the average American Knee Society Score (AKSS) was 89 with the elderly, rheumatoid patients and women having significantly lower scores.

Five years later the average AKSS had risen to 161 with patients of all ages, (including the over 80’s) gaining considerably. However, the rheumatoid patients remained more disabled as did women who had a final AKSS of 157 as opposed to 171 for the men (p< 0.01). In addition, a statistically significant finding was that those with the lowest pre-operative scores also had the lowest 5 year scores - they never catch up.

173 patients underwent bilateral knee replacement at separate times. Their pre-operative AKSS was significantly higher at the time of the second knee replacement (90) than the first (82) p< 0.01.

We conclude that since patients present earlier for their second TKR and those with most disability fail to catch up the procedure should be performed earlier in the natural history of the disease, especially in women.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 53 - 53
1 Jan 2003
Ackroyd CE Newman JH
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The aim of this study was to report our experience of patellofemoral arthroplasty in isolated osteoarthrosis.

Material and Methods: The Lubinus Patellofemoral Arthroplasty was performed between 1989 and 1995 in 76 knees. The Avon Patella Femoral Arthroplasty was used from 1996 to 2001 in 187 knees. The average age of the patients was 65.5 years (range 36–87) with a male to female ratio of 1: 5. All the patients have been prospectively reviewed with standard radiographs, the Bristol Knee Score, and more recently Bartlett and Oxford scores.

Results: Patients with the Lubinus prosthesis were followed for an average of 7.4 years (range 5–10 years). Eleven patients (14 knees) have died and the remaining 62 knees have a 100% follow-up. The cumulative revision rate was 28% (21 out of 76). Survivorship at 8 years was 65% (Cl 49 to 77) for revision and 48% (Cl 36 to 59) for revision plus moderate pain. The two main complications were Maltracking 32% and progressive tibio-femoral arthritis in 9%.

The Avon Arthroplasty with improved design features for better tracking and congruity was introduced in 1996 and 187 have now been inserted in 147 patients. One hundred and nine knees have been followed for 8 months and 82 have completed the 2 year follow-up. Two patients have undergone revision to a TKR 97.5% (survivorship 2 out of 82). Three patients have had a unicompartmental arthroplasty added for disease progression. There have been no cases of patella maltracking or subliaxation.

Four year survivorship for moderate pain and revision is 96% (79 out of 82). Functional scores compared favourably with parallel series of total knee replacements.

Conclusion: The medium-term results of the Lubinus Patello Femoral Arthroplasty are unsatisfactory. We suggest the use of this prosthesis should be discontinued. The Avon Arthroplasty has improved results in the short-term.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 53 - 53
1 Jan 2003
Desai VV Newman JH Ashraf T Beard D
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The purpose of this study was to determine the rate of polyethylene wear in a fixed bearing knee replacement in order to establish a norm against which mobile bearing implants can be judged.

Method: Eighteen all polyethylene tibial components were retrieved when a St Georg Sled unicompartmental replacement was being revised. This prosthesis has a biconvex femoral component and a totally flat tibia; thus point loading occurs on at implantation. The implants had been in situ between 6 and 110 months, revision was predominantly for progression of the arthritic process.

Linear wear was measured using an electronic micrometer and volumetric wear by creating a mould of the defect using dental wax, and subsequently weighing the wax.

Results: All components developed dishing which varied in orientation but matched the alignment of the femoral component. A near congruous articulation was thus produced correctly aligned for that particular arthroplasty. The mean linear penetrative wear for the group was 0.33mm (0.09mm per year) and the volumetric wear 124mm³ (26mm³ per year). The rate of wear seemed greatest during the second year.

Conclusion: The wear rate for this totally non congruous implant was much less than anticipated. The linear penetrative wear is comparable to that reported for Charnley hip replacement though more than for a fully congruent mobile UKR. The volumetric wear is much lower than that thought to cause osteolysis. The surprisingly low wear rate suggests that the need for mobile bearing UKRs, with their greater technical demands, should be questioned.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 36 - 36
1 Jan 2003
Kavadas V Newman JH
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The latest government targets state that by the end of 2005 the maximum waiting time for an outpatient appointment will be 3 months. These recommendations will not only increase the size of the outpatient clinics, but also the resources required thereafter. The purpose of this study was to analyse the outcome of new knee referrals to one consultant’s knee outpatient service in order to quantify the resources required to investigate and treat these patients.

All new patients attending one consultant’s knee out-patient service in the time period January 1st 1997 to December 31st 1997 were prospectively entered into a database recording patient details, source of referral and provisional diagnosis.

Eighteen months after the time period a cohort of 200 patients was randomly selected and the notes were analysed retrospectively. The number of outpatient appointment episodes (OPAs), MRI scans, physiotherapy referrals and surgical episodes generated were recorded for each patient.

Analysis of the initial database records show that a total of 662 new knee referrals were seen in 1997. 52% (341) were made up of the five most common diagnoses, these being osteoarthritis, anterior knee pain, major anterior cruciate ligament injury, medial ligament injury and medial meniscus injury.

Retrospective analysis of the 200 patient notes revealed that these patients required a total of 511 OPAs, 38 MRI scans, 178 courses of physiotherapy and 93 surgical episodes (53 elective and 40 daycase/emergency). These figures can be extrapolated to account for the total number of patients seen:

The resource implications of a new knee referral are substantial. Extra resources must accompany each new patient, otherwise, although government targets will be reached the time taken to complete each patient’s treatment will become longer. It is imperative that before an agreement is made to see new patients the resources required to manage them are in place.