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Volume 98-B, Issue SUPP_4 January 2016 The International Society for Technology in Arthroplasty (ISTA), 27th Annual Congress. PART 4.

Ashit Shah

Introduction

One of the important criteria of the success of TKR is achievement of the Flexion ROM. Various factors responsible to achieve flexion are technique, Implant and patient related. Creation of the Posterior condylar offset is one such important factor to achieve satisfactory flexion.

Aim

To correlate post op femoral condylar offset to final flexion ROM at 1 yr. post op.


Ashit Shah

Introduction

Fixed flexion isolated or along with varus / valgus is a common deformity for patients undergoing TKR. For a satisfactory outcome and normal gait post op FFD needs to be corrected completely. An additional distal femoral resection may be necessary to equalize the extension gape to correct Gr 2 FFDs.

Aim

To demonstrate full FFD correction without resecting extra distal Femur.


Ashit Shah

Introduction

Various implant designs and bearing surfaces are used in TKR. The use of All Poly Tibia and poly moulded on Tibial metal base plate has been in practice since long. Recently due to the reports on wear and osteolysis in modular articulations, these components have generated significant interest.

Aim

To report early medium term results in elderly (>70 years) patients.


Xing Yang Weishen Chen Shiming Yu Yangchun Zhang Guotian Luo Haixing Wang Puyi Sheng

Objective

To investigate the biomechanical basis and report preliminary clinical efficacy of eccentric rotational acetabular osteotomy (ERAO) when treating developmental dysplasia of the hip (DDH).

Methods

Biomechanical model of the hip joint was established on cadaveric hips. After performed ERAO on the biomechanical model, we explored the impact of this surgery on biomechanics of the hip joint. Meanwhile, we reported postoperative follow-up cases who underwent ERAO in our hospital between November 2007 to July 2012. A total of 14 patients (15 hips) were reported, including 4 males and 10 females, mean age was 30 years old. Harris hip score was defined as clinical evaluation standard and radiographic assessment was based on the measurement and further comparison of pre- and post-operative AHI (Acetabular-head index), CE angle (Center-edge angle) and Sharp angle.


Ziqing Li Yuhuan Zhou Yangchun Zhang Guotian Luo Xing Yang Chaohong Li Weiming Liao Puyi Sheng

Implant-related infection (IRI) is closely related to the local immunity of peri-implant tissues. The generation of reactive oxygen species (ROS) in activated macrophages plays a prominent role in the innate immune response. In previous studies, we indicated that implant wear particles promote endotoxin tolerance by decreasing the release of proinflammatory cytokines. However, it is unclear whether ROS are involved in the damage of the local immunity of peri-implant tissues. In the present study, we assessed the mechanism of local immunosuppression using titanium (Ti) particles and/or lipopolysaccharide (LPS) to stimulate RAW 264.7 cells. The results indicate that the Ti particles induced the generation of a moderate amount of ROS through nicotinamide adenine dinucleotide phosphate oxidase-1 (NOX-1), but not through catalase. Pre-exposure to Ti particles inhibited ROS generation and extracellular regulated protein kinase (ERK) activation in LPS-stimulated macrophages. These findings indicate that chronic stimulation by Ti particles may lead to a state of oxidative stress and persistent inflammation, which may result in the attenuation of the immune response of macrophages to bacterial components such as LPS. Eventually, immunosuppression develops in peri-implant tissues, which may be a risk factor for IRI.


Xiaojun Shi Zongke Zhou Fu-Xing Pei

Objective

To explore whether good postoperative alignment could be obtained through simple individual valgus resection angle using common instruments in total knee arthroplasty with lateral bowing femur.

Methods

Data of 46 TKAs with lateral bowing femur were collected prospectively, the center of the femoral intercondylar notch was the fixed drilling hole whether preoperative planning or intraoperative implementing. The intramedullary rod was put into the femur as deep as possible, until completely entrance or the distal point of the rod contact with the lateral cortical bone of the femur, which prevent the further entrance of the rod. Individual valgus resection angle ranging from 7°to 9°was performed according to preoperative planning, followed by meticulous assessment of matching between cutting surface and valgus resection angle. Postoperative hip-knee-ankle (HKA) angle?medial tibial plate angle and position of lower extremity alignment passing through the tibial plate were measured.


Full Access
Takashi Shibuki Fumio Sukezaki

Genesis 2 (Smith &Nephew) PS type total knee arthroplasties (TKAs) originally required measured resection technique. Between 2009 and 2013, cemented 102 TKAs were performed with modified gap technique in 29 men and 73 women with a mean age of 75 years at the time of surgery. At the time of final follow up, complications included four DVTs, one knee flexion contracture, two superficial infections. Femoro-tibial angle (FTA) was improved from 110 to 123 degrees, and mean extension of knee was improved from −8.5 to −2.1 degrees. Three TKAs with painful patello-femoral component after un-replaced patellar cases required patellar replacements. There was no radiographic evidence of loosening, osteolysis, or polyethylene wear. When patellar replacement was performed, cemented Genesis 2 PS type offered good gap balancing and excellent early outcomes with modified gap technique.


Tomonori Shigemura Shunji Kishida

Introduction

The patients with hip fracture have a general complication including heart disease. The heart echo is useful for the preoperative evaluation of cardiac function.

Objectives

The purpose of this study was to assess the relationship between echocardiographic findings and postoperative walking ability of patients with hip fracture.


Yukiyo Shimizu Hiroshi Kamada Masataka Sakane Shizu Aikawa Kenta Tanaka Hajime Mishima Akihiro Kanamori Kiyoshi Eguchi Hirotaka Mutsuzaki Yasuyoshi Wadano Naoyuki Ochiai Masashi Yamazaki

Background

Venous thromboembolisms are serious complications of arthroplasty of the lower extremities. Although early ambulation and active leg exercise is recommended, postoperative patients with surgical pain have difficulty in moving their legs. Therefore, we developed a novel leg exercise apparatus (LEX) to facilitate active leg movement even during the early postoperative period (Fig 1). LEX is a portable apparatus that allows patients to actively move their legs while in the supine position. LEX enables dorsiflexion, plantar flexion, combined eversion and inversion of the ankle, and multi-joint movement of the leg.

Objectives

To describe how LEX facilitates active movement of the leg and thereby increases venous flow in the lower extremities.


In Soo Song Sang Yeop Shin

Background

The aim of this study was to evaluate causes and results of revision surgery in unstable total knee arthroplasties.

Methods

We retrospectively reviewed 24 knees that underwent a revision arthroplasty for unstable total knee arthroplasty. The average follow-up period was 33.8 months. We classified the instability and analyzed the treatment according to its cases. Stress radiographs, postoperative component position and joint level were measured. Clinical outcomes were assessed using the score and range of motion of the Hospital for Special Surgery (HSS).


In Soo Song Sang Yeop Shin

Purpose

To evaluate the results of reverse total shoulder arthroplasty for complicated proximal humerus fractures in old ages.

Materials and Methods

We retrospectively evaluated 13 cases who underwent reverse total shoulder arthroplasty for proximal humerus fracture, fracture-dislocation and nonunions of the fractures. Mean age was 77(68–87)years old and mean follow-up period was 15.2(12–26)months. four part fractures of proximal humerus in 7 cases, fracture-dislocation in 3 cases, locked dislocation with greater tuberosity in 2 cases, nonunion with defiency of rotator cuff in 1 case were included. We evaluated mean ASES, mean UCLA, mean KSS, mean SST and mean range of motion(ROM).


In Soo Song Sang Yeop Shin

Purpose

We may consider total knee arthroplasty on one knee and unicompartmental knee arthroplasty on another knee when the patient has different grade osteoarthritis on one knee and opposite knee. Both total knee and unicompartmental knee arthroplasty had been reported as excellent clinical results, but there can be different results and different preference if the same patient undergo operation of simulataneous total knee and unicompartmental knee. We performed total and unicompartmental knee arthroplasty and pretend to report results of the clinical and radiological results and rationale of the operation.

Materials and Methods

From Marth 2007 to February 2014, 23 patients, 46 knees that underwent total knee arthroplasty and unicompartmental knee arthroplasty on knees with different osteoarthritis grade in same person enrolled in this study(Fig. 1). The mean age was 64.4 years old(range:55–75) and mean follow-up period was 25.1 months(range:13–72).


In Soo Song Sang Yeop Shin

Purpose

The purpose of this study is toevaluate the clinical and radiologic results after high flexiontotal knee arthroplasty, Lospa®(Corentec Inc.) with 10mm cutting of posterior femoral condyle and LPS-Flex®(Zimmer Inc.) with 12.5mm cutting of posterior femoral condyle.(Fig. 1)

Materials and Methods

We prospectively compared 205 knees in 128 patients who underwent arthroplasty usingLospa®(groupA) and 63 knees in 48 patients who underwentarthroplasty using NexGen LPS-Flex®(group B) from September 2010 to March 2012 at Department of Orthopaedic Surgery, Sun General Hospital (Daejeon, Korea). Mean follow-up period was 33 months(24–42) in group A and 33months(23–45) in group B, and mean age was 69.5 in group A, 70.4 in group B. The radiologic analysis included the change of mechanical axis deviation and femoro-tibial angle, implant position (α,β,γ,δ)(Fig 2). The clinical results were evaluated according to Hospital for special surgery (HSS), Knee society score (KSS), and range of motion.


Naofumi Shiota Toru Sato Tomonori Tetsunaga Kazuki Yamada

Purpose

When we perform total knee arthroplasty (TKA), the accurate osteotomy and implant setting is important as follows to improve long-term results. As means to perform osteotomy exactly, patient specific surgical instruments (PSI) patient specific surgical instruments planning based on pre-operative MRI (Signature, Materialise) and Image-free navigation system (Navi: Knee unlimited; BrainLAB) exist. However, there is not the report to compare which is exact for the same patient at the same time using two methods. We report to compare the osteotomy plans by two methods.

Materials

Nine cases of TKA (Vanguard Complete Knee System, PS, BIOMET) operated on by one operator in our hospital from October 2012 to September 2013. 78.0 years average age (71–81 years old), sex was 6 cases women, 3 men.


Takaaki Shishido Kosuke Kubo Toshiyuki Tateiwa Toshinori Masaoka Kengo Yamamoto

Introduction

In most cases of revision acetabular total hip arthoplasty (THA), some degree of bone loss will be accompanied. If the bone loss is massive, the management of bone defect is more challenging problem. We consider that using cementless accetabular cup for revision acetabular reconstruction is good indication when stable interface fit between the acetabular cup and bone is achieved. The purpose of this study is to review the result of revision hip arthroplasty using cementless acetabular cup with and without bone graft.

Materials and methods

Between 1998 and 2012, 65 revisions using cementless acetabular cup (Mallory-Head 4 Finned component) were performed in 64 patients, whose mean age was 64.9 years. The cases of revision are aseptic loosening (53 joints), and infection (12 joints). All patients were followed up for a minimum period of 24.0 months (mean, 84 months) and were divided into two groups as follows: in group A, revisions without bone graft (28 joints); in group B, revisions with bone graft (37 joints). We compared clinical and radiographical results of group A with group B.


Dong Hun Suh Seung-Beom Han Ho Hyun Yun Won Yong Shon

A retrospective analysis of 63 primary total hip arthroplasty cases was done using repeated computed tomography scans to evaluate the pelvic osteolytic lesions in early stage. The progression rate of osteolysis of hips with small osteolytic volume less than 766.97 mm(3) in initial CT was 85.82 mm(3)/year, and that of hips with osteolysis more than 766.97 mm(3) was 456.3 mm(3)/year (P < 0.001). Younger patients less than 52 years old with good Harris Hip Scores (more than 80) frequently showed much faster progression in volume of osteolytic lesions. The rate of osteolysis was accelerated when the amount of osteolysis reached a certain threshold volume in active young patients in a cascade manner even in early stage.


Nebojsa Skrepnik Scott Slagis

INTRODUCTION

Metallic ion release may be related to bearing surface wear and thus serve as an indicator of in-vivo performance of metal on metal (MOM) articulations.

OBJECTIVES

Compare large head MOM hip components with modular MOM and metal on polyethylene (MOP) to determine their relative effects on serum metal ion levels.


Claire Brockett Alexandra Smyth Miriam Day Nick Harris Susan Partridge Sophie Williams John Fisher

Introduction

Total ankle replacement (TAR) has been used as a surgical intervention for arthritis since the 1970s. However, unlike clinically successful hip and knee replacements, TARs are renowned for extensive contraindications to surgery and high failure rates with an average of 83% survival at 5 years. The majority cite aseptic loosening as the reason for failure. The aim of this study wais to analyse retrieved TARs visually and through interferometry to identify potential the failure mechanisms associated with these devices.

Methods

Retrieved total ankle replacements (n=11) from consecutive revision surgeries carried out at Chapel Allerton Hospital, Leeds between August 2012 and January 2014, were collected for study at the University of Leeds, under an NRES approved procedure (09/H1307/60).

The bearing surfaces of the samples were visually inspected for evidence of damage and wear. The bearing surfaces between the tibial component and the flat surface of the polyethylene insert were then examined using a scanning white light interferometer (NP Flex, Bruker, USA). It was not possible to characterise the talar bearing surface or the inferior polyethylene surface at this stage through interferometry due to the curvature of the surface. The components were aligned and five sections on each of the surfaces measured. These sections represented; anterior-medial, anterior-lateral, posterior-medial, posterior lateral and central regions of the bearing surfaces. 3D roughness values were recorded, and the mean 3D surface roughness compared between implants. Measurements were taken on the medial and lateral aspects of the bearing surfaces to investigate whether damage was location specific. A coefficient of determination was calculated to assess the relationship between implantation time and surface roughness.


Kazutaka So Yutaka Kuroda Koji Goto Shuichi Matsuda

Introduction

In order to reduce polyethylene wear and incidence of osteolysis, and improve the long-term durability of total hip arthroplasty (THA), highly cross-linked polyethylene was introduced for clinical use in substitution for conventional polyethylene. We performed 35 cementless THAs between December 2000 and February 2002, and cross-linked polyethylene was used in these surgeries. The purpose of this study is to research linear wear rate of these hips, and to find the risk factor for high wear rate.

Patients and Methods

32 hips (26 patients) among the 35 could be evaluated at more than 10 years postoperatively. One hip required reoperations due to infection at 8 years postoperatively, and two were lost to followup in less than 10 years. There were 2 males and 24 females, and the observation period was 11.4 years in average (range 10?13 years). The age at the time of operation was 49.4 years in average (range 24?67 years), and body mass index was 22.4 in average (15?34). We used AHFIX total hip prostheses (KYOCERA Medical Corporation) for both acetabular and femoral replacement, and 22 mm Zirconia head was used in all cases. The median cup diameter was 46 mm (range 42?50). Osteolysis and loosening of the implant was evaluated on the anteroposterior radiograph of the hip. Using software for wear measurement (Hip Analysis Suite), linear wear rate and cup inclination angle were measured. Correlation between linear wear rate and age, BMI, cup inclination angle, and cup diameter was investigated using correlation coefficient.


Lawrence Beere Sarita Bhat David Sochart

Introduction

Varus malpositioning of femoral stems has been recognised as a poor prognostic feature with regard to loosening and failure of cemented composite beam implants, but there have been no published results of the long-term effect on taper-slip designs.

Objectives

To determine the results of varus placement of a polished triple tapered femoral stem.


Akshay Hindocha Sarita Bhat David Sochart

Introduction

Traditionally it has been thought that the use of a small diameter femoral head in conjunction with a posterior surgical approach would result in a high rate of dislocation. We present the results of a consecutive series of 350 total hip replacements performed using a 22mm femoral head and a standard posterior approach, with prospective data collection.

Objective

To determine the outcome of total hip replacement using small diameter heads via a standard posterior approach.


Eunkyoo Song Jong-Keun Seon Jong-Hwan Seol

Background

Stability of total knee arthroplasty (TKA) is dependent on correct and precise rotation of the femoral component. Multiple differing surgical techniques are currently utilized to perform total knee arthroplasty. Accurate implant position have been cited as the most important factors of successful TKA. There are two techniques of achieving soft gap balancing in TKA; a measured resection technique and a balanced gap technique. Debate still exists on the choice of surgical technique to achieve the optimal soft tissue balance with opinions divided between the measured resection technique and the gap balance technique. In the measured resection technique, the bone resection depends on size of the prosthesis and is referenced to fixed anatomical landmarks. This technique however may have accompanying problems in imbalanced patients. Prediction of gap balancing technique, tries to overcome these fallacies. Our aim in this study was twofold: 1) To describe our methodology of ROBOTIC TKA using prediction of gap balancing technique. 2) To analyze the clinico-radiological outcome our technique comparison of meseaured resection ROBOTIC TKA after 1year.

Methods

Patients that underwent primary TKA using a robotic system were included for this study. Only patients with a diagnosis of primary degenerative osteoarthritis with varus deformity and flexion deformity of were included in this study. Patients with valgus deformity, secondary arthritis, inflammatory arthritis, and severe varus/flexion deformity were excluded. Three hundred ten patients (319 knees) who underwent ROBOTIC TKA using measured resection technique from 2004 – 2009. Two hundred twenty (212 knees) who underwent ROBOTIC TKA using prediction of gap balancing technique from 2010 – 2012. Clinical outcomes including KS and WOMAC scores, and ranges of motion and radiological outcomes including mechanical axis, prosthesis alignments, flexion varus/valgus stabilities were compared after 1year.


Eunkyoo Song Jong-Keun Seon Hasung Kim

Background

The most important factors affecting the outcome of a TKA are restoring the normal mechanical axis and achieving optimum soft tissue balance. In the measured resection technique may have accompanying problems in imbalanced patients. Secondly individual variability of the reference points may affect the alignment of the bony cuts and thereby the alignment of the implant. The gap balance technique blends the soft tissue balance with the bony cuts and tries to overcome this problem. However proponents of the measured resection technique argue that no consideration is given to the coronal and rotational alignment of the femoral component in the gap balance technique. The ligament specific navigation assisted gap balance technique, tries to overcome these fallacies. The lateral ligaments and soft tissues act as a reference against which the medial soft tissues are balanced. Thus the reference becomes individualized and any variability is taken care of. Navigation assistance ensures control of the coronal and rotational alignment of the femoral component. The aim of the present study was two fold: - To describe our methodology of ligament specific navigation assisted gap balance technique and analyze the clinico-radiological outcome of our technique over an eight year follow up.

Methods

79 patients (98 knees) with primary osteoarthritis with varus deformity and flexion deformity of were followed up for eight year duration. After obtaining an optimum gap balance and neutral axis in extension, tibial osteotomy perpendicular to the mechanical axis in both the coronal and sagittal planes was done. At this stage joint gaps were distracted in extension and 90â�° flexion. Based on the gap values patients were classified into three groups. Group 1 was the balanced group with flexion extension gap difference ≤2mm, group 2 was the flexion tight group with flexion gap smaller than the extension gap by ≥3mm and group 3 was the extension tight group with the extension gap smaller than the flexion gap by ≥3mm. Thereafter flexion gap balance was achieved only by adjusting the cutting levels of the distal and posterior condyles and adjusting the axial rotation of the femoral component without any further soft tissue release. Intraoperative navigation readings were recorded. All patients were followed clinico-radiologically at 1, 4, and 8 years post operatively.


Jean-Pierre St Mart Paul Whittingham-Jones Neil Davies Tim Waters

Introduction

Bone loss in the distal femur and proximal tibia is frequently encountered with both complex primary and revision knee replacement surgery. Metaphyseal sleeves provide a good option for enhanced fixation in managing such defects on both the tibia and femur. We present our results in 48 patients (50 knees) with a minimum 12 month follow up (range 12 to 45).

Methods

48 patients (50 knees) who had revision knee arthroplasty for either septic or aseptic loosening. All were graded Type II or III using the Anderson Orthopaedic Research Institute (AORI) grading system of both femoral and tibial defects. A large portion of aseptic loosening revisions were for extreme osteolysis of a bicondylar knee prosthesis.


Anneka Stevens Chris Wilson Meenu Shunmugam Vijai Ranawat Jegan Krishnan

Inter- and intra-observer variation has been noted in the analysis of radiographic examinations with regard to experience of surgeons, and the monitors used for conducting the evaluations. The aim of this study is to evaluate inter/intra observer variation in the measurement of mechanical alignment from long-leg radiographs.

40 patients from the elective waiting list for TKA underwent long leg radiographs pre-operatively and 6 months post-operatively (total of 80 radiographs). The x-rays were analysed by 5 observers ranging in experience from medical student to head orthopaedic surgeon. Two observers re-analysed their results 6 months later to determine intraobserver correlation, and one observer re-measured the alignment on a different monitor. These measurements were all conducted blindly and none of the observers had access to the others’ results.

80 radiographs were analysed in total, 40 pre-op and 40 post-op. The mechanical alignment was analysed using Pearson's correlation (r = 0 no agreement, r = 1 perfect agreement) and revealed that experience as an orthopaedic surgeon has little effect on the measurement of mechanical alignment from long leg radiograph. The results for the different monitor analysis were also analysed using Pearson's correlation of long leg alignment. Monitor quality does seem to affect the correlation between alignment measurements when reviewing both intra and inter observer correlation on different computer monitors.

Surgical experience has little impact on the measurement of alignment on long leg radiographs. Of greater concern is that monitors of different resolution can affect measurement of mechanical alignment. As there might be a range of monitors in use in different institutions, and also in outpatient clinics to surgical theatres, close attention should be paid to the implications of these results.


Anneka Stevens Saleem Hussenbocus Chris Wilson Graham Mercer Jegan Krishnan

Introduction

Total hip replacement (THR) is a very common procedure performed for the treatment of osteoarthritis of the hip. The aim of THR is to restore function and quality of life of the patients, by restoring femoral offset, leg length, centre of rotation, and achieving stability, to avoid dislocation postoperatively.

Method

We aimed to perform preoperative assessment of femoral offset on anteroposterior (AP) radiographs of the hip, and on corresponding CT scans, for patients undergoing primary THR. Patients were positioned according to a standardised protocol prior to obtaining radiographs of the hip and CT scan. Inter- and intra-observer reliability was evaluated between 3 observers of differing levels of seniority – an orthopaedic trainee, a fellow, and a consultant. CT scan measurements of offset were performed by one consultant radiologist. The researchers measuring radiographic offset were blinded to the results of the CT measurements.


Anneka Stevens Chris Wilson Graham Mercer Jegan Krishnan

Introduction

There are conflicting views when assessing the best imaging modality by which to assess long leg alignment pre and post operatively for patients’ receiving primary total hip replacements. It has been a long standing standard that long-leg radiographs are used for measuring and interpreting alignment of the lower limb, but recently it has been suggested that CT imaging may be a better option for this assessment.

Methods

Patients awaiting total knee replacement surgeries were invited to participate in this clinical trial. 120 participants’ consented and completed both pre and post-operative long-leg radiographs, and lower limb CT scans. Long leg radiographs were analysed and measured by senior orthopaedic surgeons pre and post-operatively, while CT scans were analysed using the perth protocol method by trained radiologists. Mechanical alignment of the lower limb was calculated using both imaging modalities, the CT “scout” scan was used for the measurement of the mechanical alignment.

Pre-operatively the patients had their imaging performed between 1 year and 1 week pre-operatively, and following surgery their imaging was standardised to 6 months post-operatively. For long leg radiographs, patients were asked to stand with their feet shoulder width apart and toes forward facing (on occasion deformities would not allow for this stance, and they were asked to adopt this stance to the best of their ability).


Paul Stirling Rejith Valsalan Mannambeth J. Agustin Soler Vineet Batta Rajeev Kumar Malhotra Yegappan Kalairajah

Introduction

Increased accuracy of pre-operative imaging in patient-specific instrumentation (PSI) can result in longer-term savings, and reduced accumulated dose of radiation by eliminating the need for post-operative imaging or revision surgery. The benefits and drawbacks of CT vs MRI for use in PSI is a source of ongoing debate. This study reviews all currently available evidence regarding accuracy of CT vs MRI for pre-operative imaging in PSI.

Methods

The MEDLINE and EMBASE databases were searched between 1990 and 2013 to identify relevant studies. As most studies available focus on validation of a single technique rather than a direct comparison, the data from several clinical studies was assimilated to allow comparison of accuracy. Overall accuracy of each modality was calculated as proportion of outliers >3 % in the coronal plane.


Nick Stroud Cameron Staunch

Introduction

Implant stability immediately after implantation is vital for long term success and improvement in patient outcomes for total hip arthroplasty (THA). Of the many factors that influence stability and resistance to migration for press-fit metaphaseal-fixed stems, this work attempted to evaluate the effect of distal stem taper angle on initial stem axial stability. Two THA stem designs having a distal taper angle of 3.5° and 5° were evaluated with cadaveric specimens with a simulated walking gait while stem motion was measured with respect to the periprosthetic bone.

Methods


Shyam Vekaria Victoria Brander Michelle Hansen S. David Stulberg

Introduction

Neck-stem corrosion has been associated with Adverse Local Tissue Reaction (ALTR) in dual-taper femoral stems. Several diagnostic tests, of varying specificity and sensitivity, are used to identify ALTR. The purpose of this study was to document the clinical presentation, diagnostic workup and surgical findings in a large cohort of patients with dual modular stems, and use this information to propose an evaluation protocol that assists surgical decision-making.

Methods

This is a single center, single surgeon's retrospective case series of 38 patients who underwent 42 primary total hip arthroplasty (THA) with a dual-taper femoral components between March 2010 and May 2011 The evaluation included clinical exam, hip radiographs, labs including serum metal ion levels, metal artifact reduction sequence magnetic resonance imaging (MARS MRI), and fluoroscopic hip aspiration with qualitative and quantitative assessment of synovial fluid. Each hip aspirate was classified into Class 1 (clear, <10cc), 2(brown, clear, >10cc), or 3 (cloudy, turbid, viscous). 20 patients to date have undergone revision THA.


S. David Stulberg Nitin Goyal

Introduction

The goal of tibial tray placement in total knee arthroplasty (TKA) is to maximize tibial surface coverage while maintaining proper rotation. Maximizing tibial surface coverage without component overhang reduces the risk of tibial subsidence. Proper tibial rotation avoids excess risk of patellar maltracking, knee instability, inappropriate tibial loading, and ligament imbalance. Different tibial tray designs offer varying potential in optimizing the relationship between tibial surface coverage and rotation. Patient specific instrumentation (PSI) generates customized guides from an MRI- or CT-based preoperative plan for use in TKA. The purpose of the present study was to utilize MRI information, obtained as part of the PSI planning process, to determine, for anatomic, symmetric, and asymmetric tibial tray designs, (1) which tibial tray design achieves maximum coverage, (2) the impact of maximizing coverage on rotation, and (3) the impact of establishing neutral rotation on coverage.

Methods

In this prospective comparative study, MR images for 100 consecutive patients were uploaded into Materialise™ PSI software that was used to evaluate characteristics of tibial component placement. Tibial component rotation and surface coverage was analyzed using the preoperative planning software. Anatomic (Persona™), symmetric (NexGen™), and asymmetric (Natural-Knee II™) designs from a single manufacturer (Zimmer™) were evaluated to assess the relationship of tibial coverage and tibial rotation. Tibial surface coverage, defined as the proportion of tibial surface area covered by a given implant, was measured using Adobe Photoshop™ software (Figure 1). Rotation was calculated with respect to the tibial AP axis, which was defined as the line connecting the medial third of the tibial tuberosity and the PCL insertion.


Tanzo Sugimori Yoshiyuki Tachi Ryoji Tsuda Ayumi Kaneuji Tadami Matsumoto

Background

To prevent excessive tension on the posterior cruciate ligament (PCL) in cruciate-retaining total knee arthroplasty (CR-TKA), some knee prosthesis-systems offer the option of creating a posterior slope for the tibial polyethylene insert. Vanguard® Complete Knee System offers two different types of tibial bearing for CR

-TKA. CR Lipped Bearing (LB) has a slightly raised posterior lip, whereas CR Standard Bearing (SB) is recessed downward at the posterior margin and has 3° posterior slope. The objective of this study was to investigate the effect of the tibial bearing slope on PCL load using the original devise in vivo conditions.

Material and Methods

Twenty osteoarthritic varus knees were included in this study. After implantation of the trial components, PCL stiffness was measured using the original tension analyzer intra-operatively. Elastic modulus of PCL was calculated at 90 and 120 degrees knee flexion on two types of bearing surface.


Takehiko Sugita Naohisa Miyatake Akira Sasaki Ikuo Maeda Tetsuo Honma Toshimi Aizawa

Introduction

Various methods to manage medial tibial defects in primary total knee arthroplasty (TKA) have been described. According to Vail TP, metal augmentation is usually indicated for defect depth of >10 mm of the medial tibial plateau. The outcomes of metal augmentation have been described as excellent. Nevertheless, we believe that it is mandatory to preserve as much of the bone as possible for future revision surgeries. Therefore, we performed autologous impaction bone grafting even for large bone defects (defect depth of ≥10 mm) in primary TKA. The objectives of this study are to describe our bone grafting technique in detail and to assess the radiological outcomes of the grafted bone.

Methods

Between 2003 and 2011, 26 TKAs with autologous impaction bone grafting for ≥10 mm medial tibial defects were performed. The preoperative diagnoses were osteoarthritis in 17 knees, rheumatoid arthritis in 2 knees, osteonecrosis of the medial tibial condyle in 6 knees, and Charcot's joint in 1 knee. The average mediolateral width and depth of the medial tibial defects, measured after the horizontal osteotomy of the tibial articular surface, were 17.8 mm (range, 10–25 mm) and 12.0 mm (range, 10–23 mm), respectively. The average patient age at surgery was 73.2 years (range, 56–85 years). The patients were followed up for an average of 55 months (range 27–109 months).

Bone grafting technique: Multiple drill holes (white arrow) were made on the floor of the defect (A) and a morselized cancellous bone was impacted using the grip end of a metal hammer (white asterisk) and firm manual pressure to fill the defect. Thus, the firm impaction prevented bone cement from entering the space between the graft and the tibial host bed. An assistant's index finger (black asterisk) was used as a bank (B). The tibial component was fixed on the grafted bone (white asterisk) with bone cement (C). Internal fixation devices were not required, and stem extension was used in only Charcot's joint (defect depth=23 mm). Aftertreatment was the same as that for the usual TKAs without bone defects.


Dong Hun Suh Won Yong Shon

Titanium (Ti) is well known in orthopedic implant materials such as total hip replacement arthroplasty. Osseointegration of orthopedic implants is defined as the formation of a direct interface between the implant and the bone without intervening soft tissue. Unmodified Ti is not sufficient to complete adhesion between Ti surface and host bone with subsequent implant loosening over time and ultimately implant failure. An effective approach to enhance the biological activity of orthopedic implants and improve post-implantation healing is to modify the implant surface. The aim of this study was to investigate the effect of functionalized titanium (Ti) with alendronate (Aln) and bone morphogenic protein-2 (BMP-2) for enhancement of osteoblast activity in vitro.

Aln and/or BMP-2 were sequentially immobilized to the heparinized-Ti (Hep-Ti) surface. The compositions of pristine Ti and Hep-Ti with or without Aln and/or BMP-2 were characterized by scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). Osteoblast activities on all Ti substrates were investigated by cell proliferation assays, alkaline phosphate (ALP) activity, calcium deposition, gene expressions of osteocalcin and osteopontin.

The modified Ti surface with heparin, Aln, BMP-2 and Aln/BMP-2 showed similar morphologies compared to that of pristine Ti on scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS). Aln or BMP-2 from Aln/Hep-Ti, BMP-2/Hep-Ti or Aln/BMP-2/ Hep-Ti substrates exhibited sustained release profiles up to 4 weeks. No significant cytotoxic effects were observed for incubation periods for up to 48 h. the ALP activity of MG-63 cells cultured on Hep-Ti was not significantly different compared to those cultured on pristine Ti for 7, 14, and 21 days. Alkaline phosphatase(ALP) activities of osteoblasts cultured on Ti groups immobilized with Aln, BMP-2, or Aln/BMP-2 were significantly increased when compared to pristine Ti(p < 0.05). Calcium deposition was markedly increased in Aln/BMP-2/Hep-Ti compared to Aln/Hep-Ti or BMP-2/Hep-Ti, respectively (p < 0.05). mRNA expressions of osteocalcin(OCN) and osteopontin(OPN) of osteoblasts grown on Aln/Hep-Ti, BMP-2/Hep-Ti, and Aln/BMP-2/Hep-Ti were significantly higher than of those grown on pristine Ti (p < 0.05).

Based on the results of the in vitro studies, we showed that co-delivery of alendronate and BMP-2 had an additive effect on osteoblast activity and mineralization when compared with pristine Ti as well as alendronate or BMP-2 alone. Functionalized Ti systems with alendronate and BMP-2 can give a good solution to solve the most common problems associated with orthopedic and dental implants. Furthermore, in vivo studies required to determine the optimal doses of alendronate and BMP-2 for clinical application.


Won Yong Shon Ho Hyun Yun Dong Hun Suh

The PowerPoint (2007 Version; Microsoft, Redmond, Wash) method is reported to have improved repeatability and reproducibility and is better able to detect differences in radiographs than previously established manual wear measurement methods. In this study, the PowerPoint method and the Dorr and Wan method were used to calculate the polyethylene liner wear volume. The wear volumes of retrieved polyethylene liners calculated from the 3D laser scanning method were compared with each method. This study hypothesized that the wear volume calculated by the PowerPoint method would correlate well with the wear volume measured by 3D laser scanning method.

Between March 2004 and June 2009, 22 polyethylene liners from 20 patients were collected during revision Total hip arthroplasty(THA). Exclusion criteria included (1) missing an early primary postoperative radiograph or prerevision radiograph, (2) evidence of acetabular loosening or migration, (3) existence of significant mismatch between early primary postoperative radiograph and prerevision radiographs on vertical axis, and (4) liner wear-through. After applying these exclusion criteria, 17 retrieved polyethylene liners from 16 patients were included in this study. Wear volumes were calculated using the PowerPoint, the Dorr and Wan methods by 3 independent experienced observers who were unaware of the study design, and 3-dimensional (3D) laser scanning methods.

Spearman correlation coefficients for wear volume results indicated strong correlations between the PowerPoint and 3D laser scanning methods (range, 0.89–0.93). On the other hand, Spearman correlation analysis revealed only moderate correlations between the Dorr and Wan and 3D laser scanning methods (range, 0.67–0.77).

The PowerPoint method is an efficient tool for the sequential radiologic follow-up of patients after THA. The PowerPoint method can be used to monitor linear wear after THA and could serve as an alternative method when computerized methods are not available.


Takanobu Sumino Shu Saito Takao Ishii

Introduction

The Flexible Nichidai Knee (FNK) System (Nakashima Medical, Japan) was designed to fit Asian knees. Especially, the posterior stabilized(PS) prosthesis was designed as semi-constrained posterior stabilized system that had a large tibial post and femoral articulation. We hypothesized that the semi-constrained PS implant design would have a positive influence on vivo kinematics after total knee arthroplasty (TKA).

Materials and Methods

A total of 16 patients (21 knees) who had undergone TKA using PS implant were randomly recruited from our database. Of the 16 patients, all patients were women. Fourteen patients had osteoarthritis and 2 patients had rheumatoid arthritis. The average age was 72.3± 9.5 years, and the average postoperative duration was 23.4 ± 19.3 months. The subject performed sequential deep knee bends under WB from 0° to maximum flexion under fluoroscopic monitoring in the sagittal plane. Conversely, under NWB, the patient sat on a chair and was asked to perform active assisted knee flexion. To estimate spatial position and orientation of the artificial knee prosthesis, a 2D to 3D registration technique was used. We evaluated knee range of motion, femoral axial rotation relative to the tibial component, and anteroposterior translation of the femorotibial contact point for both medial and lateral sides. Closest distances between femoral cam and tibial post engagement were measured,


Anneka Stevens Rohilla Surabhi Ruurd Jaarsma Donald Bramwell Jegan Krishnan

Introduction & aims

Different racial groups show variations in femoral morphometry. Femoral anteroposterior measurement and mediolateral measurement are key variables in designing femoral implant for TKR. Their aspect ratio determines the shape and mediolateral sizing for the proper patellofemoral tracking and uniform stress distribution over the resected distal femoral surface.

Method

We reviewed the current literature in December 2013 in common medical databases including the Cochrane Library, PubMed and Medline. Keywords included combinations of: Anthropometry, Knee, Arthroplasty, Femur, Morphometry, Geometry. We selected papers including femoral morphometric data collected from populations of different ethnic origins. Papers covered populations in the USA, China, Germany, Thailand, Korea, India, Japan and Malaysia.


Ettore Vulcano Michele Surace Luca Monestier Steven F Harwin Paolo Cherubino

Polyethylene wear is the main factor leading to periprosthetic osteolysis, aseptic loosening and long-term failure of the implant in total hip arthroplasty (THA). The present study compares the clinical and radiographic outcomes of 88 patients who underwent primary THA with either conventional polyethylene or cross-linked polyethylene (XLPE) from the same manufacturer (Zimmer®, Warsaw, IN, USA). There were no significant differences between the two sub-populations in average age, gender, side affected and prosthetic stem and cup size. The average follow-up was 104 months, ranging from 55 to 131 months: to our knowledge this is the longest follow-up for this particular insert. Clinical and x-ray evaluation was obtained at 1, 3, 6 and 12 months and yearly thereafter. Our results showed that cross-linked polyethylene has a significantly greater wear reduction than that of standard polyethylene.


Koji Suzuki Noriyuki Hara Susumu Mikami Tetsuya Tomita Keiji Iwamoto Takaharu Yamazaki Kazuomi Sugamoto Shigeo Matsuno

Backgrounds

Most of in vivo kinematic studies of total knee arthroplasty (TKA) have reported on varus knee. TKA for the valgus knee deformity is a surgical challenge. The purposes of the current study are to analyze the in vivo kinematic motion and to compare kinematic patterns between weight-bearing (WB) and non-weight-bearing (NWB) knee flexion in posterior-stabilized (PS) fixed-bearing TKA with pre-operative valgus deformity.

Methods

A total of sixteen valgus knees in 12 cases that underwent TKA with Scorpio NRG PS knee prosthesis operated by modified gap balancing technique were evaluated. The mean preoperative femorotibial angle (FTA) was 156°±4.2°. During the surgery, distal femur and proximal tibia was cut perpendicular to the mechanical axis of each bone. After excision of the menisci and cruciate ligaments, balancer (Stryker joint dependent kinematics balancer) was inserted into the gap between both bones for evaluation of extension gap. Lateral release was performed in extension. Iliotibial bundle (ITB) was released from Gerdy tubercle then posterolateral capsule was released at the level of the proximal tibial cut surface. If still unbalanced, pie-crust ITB from inside-out was added at 1 cm above joint line until an even lateral and medial gap had been achieved. Flexion gap balance was obtained predominantly by the bone cut of the posterior femoral condyle. Good postoperative stability in extension and flexion was confirmed by stress roentgenogram and axial radiography of the distal femur. We evaluated the in vivo kinematics of the knee using fluoroscopy and femorotibial translation relative to the tibial tray using a 2-dimentional to 3-dimensional registration technique.


Masahiko Suzuki Wakako Shirasaka Etsuji Yamamoto Keita Uetsuki MItsuru Sakai Junichi Nakamura Takahisa Sasho Kazuhisa Takahashi

Introduction

In total knee arthroplalsties, there are risks of revision surgeries because of aseptic loosening, polyethylene wear, and metal component breakage. The data such as model, type, size, and manufacturing companies are required at the time of revision surgeries. However, it is sometimes difficult to acquire such data due to patient's change of address and the elimination and consolidation of hospitals in the long-term. Therefore, we try to use the Radio Frequency IDentification (RFID) in the total knee joint system.

Materials and methods

The FerVID family (Fujitsu Co. Ltd., Tokyo, Japan) was prepared as the RFID tag. It was radio-resistant below the dose of 50kGy, which allowed gamma sterilization. The RFID tags were embedded into the anterior side of GUR 1050 UHMWPE inserts and 0.3wt% vitamin E blended UHMWPE. The UHMWPE inserts were manufactured by thecompression molding method at the maximum temperature of 220°C and the maximum compressive force of 245kgf/cm2. The manufactured inserts were implanted in fresh cadaveric knees. The tibial base plate was made of Ti6Al4V. The femoral components were made of Co-Cr-Mo or Ti-6Al-4V. Communication Performance was measured with the interrogator (DOTR-920 MHz-band, Tohoku Systems Support Co. Ltd., Miyagi, Japan). The transmission output was up to 1W. Received Signal Strength Indicator (RSSI) was measured 500 times at 15 mm away from the surface of skin in the extension and 90° flexion of the knee (Fig1).


Chiho Suzuki Satoshi Iida

Introduction

Dislocation is one of severe complications after total hip arthroplasty (THA). Direct anterior approach (DAA) is useful for muscle preservation. Therefore, it might be also effective to reduce dislocation. The purpose of this study is to investigate the ratio and factors of dislocations after THA with DAA.

Materials & methods

Nine hundred fifity two primary THAs with DAA are examined. Mean age at operation was 64.9 yrs. 838 joints are in women and 114 (joints) in men. All THAs were performed under general anesthesia in supine position.

We reviewed the ratio, onset and frequency of dislocations, build of the patients, preoperative Japanese Orthopaedic Association (JOA) Hip scores, implant setting angles, pelvic tilt angles and diameter of inner heads.


Baha John Tadros Tarang Tandon Christopher Gee Biyyam Rao

Background

Hospital acquired MRSA is globally endemic and is a leading cause of surgical site infection (SSI). Of great concern is the emergence of community acquired MRSA (CA MRSA) with its unique virulence characteristics. Infected hip or knee prostheses due to MRSA are associated with multiple reoperations and prolonged hospital stay. Few studies have been done to assess for risk of SSI in MRSA carriers undergoing elective orthopaedic surgery following decolonisation. However in these studies, the eradication status was not confirmed prior to proceeding for surgical intervention.

Aim

The purpose of the study was to evaluate the incidence of SSI in MRSA carriers undergoing elective hip and knee arthroplasty, who had confirmed eradication of MRSA carrier status and to compare it with incidence of SSI in non MRSA carriers.


Ta-Wei Tai Tzu-Chieh Lin Chia-Jung Ho Yea-Huei Yang Kao Chyun-Yu Yang

BACKGROUND

Periprosthetic infection is the most challenging complication following total knee arthroplasty (TKA). Poor oral hygiene has been assumed as an important risk factor for TKA infection. We aimed to investigate whether the improvement of oral hygiene through dental scaling could reduce the risk of TKA infection.

METHODS

A nested case control study was conducted and enrollees in the National Health Insurance Research Database (NHIRD) aged above 40 years who had received total knee arthroplasty (TKA) between 1999–2002 were included as the TKA cohort. The cases were patients who underwent resection arthroplasty for infected TKA, and each case was matched by 4 controls from the TKA cohort by gender, using incidence density sampling method. The frequency of dental scaling before the index date was analyzed and compared between the case and the control groups. Multiple conditional logistic regression was used to assess the frequency of dental scaling and the risk of TKA infection.


Yasuhito Takahashi Giuseppe Pezzotti Kengo Yamamoto

Introduction

Vitamin-E (VE, dl-α-tocopherol) is a powerful antioxidant for highly cross-linked polyethylene (XLPE). It was previously reported that VE-stabilized XLPE succeeded in retaining no measurable oxidation even after accelerated aging tests combined with cyclic loading or lipid absorption. Thus, VE-stabilized XLPE is nowadays recognized worldwide as one of the new standard materials in total hip arthroplasty (THA). However, the effects of such VE addition on physical behavior of polyethylene remain to be fully elucidated by contrast to the clear statement of its chemical role (i.e., the enhanced oxidation resistance) in the published literature. In this presentation, we shall attempt to provide those missing notations and to explore the microstructural and biomechanical role of VE in XLPE acetabular liner on the molecular scale.

Methods

The two different types of XLPE acetabular liners, VE-blended and VE-free (no VE-blended) component (n=3 for each sample), were investigated by means of laser-scanning confocal polarized micro-Raman spectroscopy. In both components, the cross-linking was achieved by electron-beam irradiation with a total dose of 300kGy in vacuum. Raman spectroscopy offers non-destructive, contactless, and high-resolution analyses of polymer morphologies. In this study, we performed an in-depth profiling of crystalline and non-crystalline phase (i.e., amorphous and intermediate phase between crystalline and amorphous regions) percentages and degree of molecular orientation in the above two liners before and after introducing the 10% plastic deformation via uniaxial compression loading at room temperature. These results were also compared to the morphological analyses under the same compression conditions performed on the virgin conventional polyethylene (Virgin liner) without radiation crosslinking as well as VE blending.


Yuya Takakubo Kan Sasaki Atsushi Narita Hiroharu Oki Yasushi Naganuma Tomoyiki Hirayama Akemi Suzuki Yasunobu Tamaki Eita Togashi Hiroyuki Kawaji Shigenobu Fukushima Masaji Ishii Michiaki Takagi

Objectives

Biologic agents (BIO) drastically changed the rheumatoid arthritis (RA) therapy from starting to use biologics at 2003 in Japan. The rate of orthopaedic surgery, especially total joint arthroplasty (TJA) may reflect trends in disease severity, management and health outcomes.

Methods

We surveyed the number and rate of orthopaedic surgeries and TJA in RA treatment with BIO in the last decade, so called BIO-era.


Hirofumi Takami

Purpose

Placement of the acetabular cup in accurate and optimal position is important in total hip arthroplasty (THA) to obtain satisfactory result. On the other hand, inaccurate manual cup placement with conventional cup placement guide was reported. We therefore have been applied the mechanical acetabular alignment guide for accurate cup placement. The purpose of this study was to validate the accuracy of the acetabular alignment guide for total hip arthroplasty.

Materials and methods

Between 2003 and 2014, 52 primary THAs were performed in 48 patients with using the acetabular alignment guide by one surgeon (HT). There were 42 female and 6 male with a mean age at operation of 71.1 years old (47 to 91). The original diagnosis were osteoarthritis in 43 patients (46 hips), and avascular necrosis of femoral head in 5 patients (6 hips). Used acetabular implants were Stryker® Trident AD HA cup in 24 hips and Wright medical® Acetabular Cup System in 28 hips.

After completion of anesthesia, half pins were inserted at the both anterior superior iliac spine vertically and the frame was attached to the pins horizontally in supine position. Then, the patients were placed in lateral decubitus position. Finally, the alignment rod, which indicated the optimal direction of the cup (abduction angle 40°, ante-version angle 20°), was connected to the frame. All operations were done by postero-lateral approach. Assessment of the cup abduction angle and ante-version angle was performed by Lewinnek's method using postoperative AP radiograph in supine position.


Masaki Takao Takashi Nishii Takashi Sakai Nobuhiko Sugano

In total hip arthroplasty (THA), inappropriate cup alignment cause edge loading and prosthetic impingement, which lead to various mechanical problems including dislocation, excessive wear and breakage of bearing materials, and stem neck fracture. To find the optimal cup alignment, various computer simulation studies have been conducted. However there have been few studies focusing on pelvic coordinate system as a reference of cup positioning. Our hypothesis is that the functional pelvic coordinate system with pelvic sagittal inclination in the supine position is appropriate for a reference frame of cup alignment. To test the hypothesis, we have been investigating preoperative and postoperative kinematics of pelvis and hip of THA patients.

In 25 % of the consecutive 163 patients, the difference in preoperative pelvic inclination angle between the supine and standing positions (positional change of pelvic inclination [PC]) was 10o or more. Patients’ age and age-related spinal disorders including compression fracture and lumbar spondylolisthesis were independent factors associated with large preoperative PC. This raises a concern that large PC might increase the risk of edge loading and posterior prosthetic impingement when cup was positioned referencing supine pelvic position, especially in elderly patients.

We compared kinematics of the hip after THA in patients with a preoperative large PC (≥10°) with that in patients with a preoperative small PC (<10°), assuming that the supine position as a zero position of the pelvis. First, we compared intraoperative passive range of motion (ROM) after implantation of the 91 hips using navigation system. No significant differences in intraoperative hip ROM were observed between the both groups. Next, we compared postoperative ROM of the 50 hips during motion of daily livings using our 4-dimentional motion analysis system within two year after THA. No significant differences in postoperative hip flexion or extension angles were observed between the both groups. These results suggested that if cup was positioned referencing the supine pelvic position, the degree of preoperative PC does not matter early after primary THA.

Regarding long-term change of pelvic inclination after THA, 49 % of 70 patients followed for 10 years showed the change more than 10o in the standing position, although only 9% showed the change more than 10o in the supine position. This means that aging after THA increase discrepancy of pelvic inclination between the preoperative supine position as the reference for preoperative planning and the postoperative standing positions in some patients. However we could not find any preoperative predictors of this long-term change of pelvic inclination in the standing position. Therefore, although it is unclear whether surgeons should change the reference pelvic plane for cup alignment taking the longitudinal change of pelvic inclination in the standing position, at least, strict cup alignment control at primary THA is considered to be important to minimize the risk of edge loading and prosthetic impingement due to longitudinal changes of pelvic inclination.

In conclusion, our current recommendation of pelvic coordinate system as a reference of cup alignment is a functional pelvic coordinate system with pelvic sagittal inclination in supine position.


Koji Takayama Tomoyuki Matsumoto Hirotsugu Muratsu Naoki Nakano Nao Shibanuma Katsumasa Tei Takehiko Matsushita Ryosuke Kuroda Masahiro Kurosaka

Purpose

The tibia first technique in unicompartmental knee arthroplasty (UKA) may have the advantage that surgeons can obtain a balanced flexion-extension gap. However, changes of the soft tissue tension during UKA has not been elucidated yet. The purpose of this study was to examine the correlation between the soft tissue tension before the femoral osteotomy and after the femoral component in place using the tensor in UKA.

Methods

Thirty UKAs for isolated medial compartmental osteoarthritis or idiopathic osteonecrosis were assessed. The mean age was 71.8±8.5 years old (range: 58–85), and the average coronal plane femorotibial angle (FTA) was 181.2±3.2 degree preoperatively. All the patients received a conventional medial Zimmer Unicompartmental High Flex Knee System (Zimmer Inc, Warsaw, Ind). The actual values of the proximal and posterior femoral osteotomy were calculated by adding the thickness of the bone saw blades to the thickness of the bony cut. Using a UKA tensor which designed to facilitate intra-operative soft tissue tension throughout the range of motion (ROM), the original gap before the femoral osteotomy, the component gap after the femoral osteotomy, and component placement were assessed under 20 lb distraction forces. (Figure 1)


Mitsuhiro Takeda Ishii Yoshinori Noguchi Hideo Sato Junko

Introduction

The low-contact stress (LCS) knee prosthesis is a mobile-bearing design with modifications to the tibial component that allow for meniscal-bearing (MB) or rotating-platform (RP). The MB design had nonconstrained anteroposterior and rotational movement, and the RP design has only nonconstrained rotational movement. The anterior soft tissues, including patellar tendon (PT), prevent anterior dislocation of the MB. The PT may consistently be exposed to overstressing. Therefore, we hypothesized that the PT thickness and width in MB prosthesis revealed more morphological changes than those of RP prosthesis due to degeneration of the PT induced by much mechanical stress of the MB movement. To confirm this hypothesis, we analyze the PT thickness and width induced by mobile-bearing inserts.

Objectives

Sixty LCS prostheses in 30 patients were analyzed. The average follow-up time was 61 months. MB prosthesis was used on one side of the knee and RP prosthesis was used on the contralateral side of the knee. All patients were chosen from group with no clinical complication, and all had achieved passive full extension and at least 90°of flexion. The average Hospital for Special Surgery Score was 94.6 ± 2.7.


Toshiyuki Takemori Hirotsugu Muratsu Yoshiki Takeoka Tomoyuki Matsumoto Yoshinori Takashima Masanori Tsubosaka Takashi Oshima Akihiro Maruo Hidetoshi Miya Ryosuke Kuroda Masahiro Kurosaka

Objective

The goal of total knee arthroplasty (TKA) is to achieve a stable and well-aligned tibiofemoral and patello-femoral (PF) joint, aiming at long-term clinical patient satisfaction. The surgical principles of both cruciate retaining (CR) and posterior stabilized (PS) TKA are accurate osteotomy and proper soft tissue balancing. We have developed an offset-type tensor, and measured intra-operative soft tissue balance under more physiological joint conditions with femoral component in place and reduced PF joint.

In this study, we measured intra-operative soft tissue balance and assessed the post-operative knee joint stability quantitatively at one month, six months and one year after surgery, and compared these parameters between CR and PS TKAs.

Material and Method

Sixty patients with varus osteoarthritis of the knee underwent TKAs (30 CR TKAs: CR and 30 PS TKAs: PS). Mean varus deformity in standing position was 11.1 degrees in CR, and 12.6 degrees in PS. All TKAs were performed by a single surgeon with measured resection technique. The external rotation of posterior femoral condyle osteotomy was performed according to surgical epicondylar axis in pre-operative CT. We measured intra-operative soft tissue balance using an offset-type tensor with 40 lbs of joint distraction force at 0, 10, 30, 45, 60, 90, 120 and 135 degrees of flexion. The joint component gap (mm) and varus angle (degrees) were measured at each flexion angles.

One month, six months and one year after surgery, we evaluated the knee stability at extension by varus and valgus stress radiography using Telos (10kg) and at flexion by epicondylar view with 1.5kg weight at the ankle. We measured joint separation distance at medial as medial joint looseness (MJL) and at lateral as lateral joint looseness (LJL). Intra-operative measurements and post-operative joint stabilities were compared between CR and PS using unpaired t-test. The change of joint looseness in each group was analyzed using repeated measures ANOVA.


Naoya Taki Naoto Mitsugi Yuichi Mochida Masato Aratake Kentaro Shinohara Hirohiko Ota Yohei Sasaki

Introduction

Planning of the stem antetorsion angle (SAA) is difficult with radiograph before THA. 3D THA planning software with CT is useful for planning the cup and the stem implantation angles before THA. However, even using the 3D planning software, we sometimes experience the different SAA during surgery compare to the planned SAA. The purpose of this study was to compare the implanted SAA with the preoperative planned SAA, which was planned by using 3D THA planning software.

Materials and Methods

CT evaluation was performed in 44 patients (5 males) who underwent primary THA. The mean age at surgery was 67 years (range 26–85 years). The mean BMI at surgery was 24.1kg/m2 (15.6–31.7kg/m2). Forty-one patients had osteoarthrosis, 2 patients had osteonecrosis, and 1 patient had femoral neck fracture. All surgeries were performed in the supine position with the direct anterior approach. The OrthoPilot imageless navigation system (BBraun/Aesculap) was used during surgery. Excia stem was used in 34 patients and Bicontact stem was used in 10 patients. Planning of the surgery was performed using 3D THA planning software (ZedHip, Lexi). After surgery, SAA was measured with CT by the same 3D THA planning software. SAA was evaluated by comparison of the planned values before surgery with the CT measured values. Also, the shape of the femur and the stem were evaluated.


Iori Takigami Hiromi Otsuka Toshiki Iwase Hiroshi Fujita Haruhiko Akiyama

Background

Impaction bone grafting (IBG) using a circumferential metal mesh is one of the options that allow restoration of the femoral bone stock and stability of the implant in hip arthroplasty. Here we examined the clinical and radiographic outcome of this procedure with a cemented stem and analyzed experimentally the initial stability of mesh–grafted bone–cemented stem complexes.

Methods

We retrospectively reviewed 6 hips (6 patients) that had undergone femoral revisions with a circumferential metal mesh, impacted bone allografts, and a cemented stem. The mean follow-up period was 2.9 years (range, 1.4–3.8 years). Hip joint function was evaluated with the Japanese Orthopaedic Association hip score, and radiographic changes were determined from radiographs. The initial resistance of cemented stem complexes to axial and rotational force was measured in a composite bone model with various segmental losses of the proximal femur.


Rushi Talati Hasham Alvi Patrick Sweeney Anay Patel S. David Stulberg

Introduction

Total knee arthroplasty is effective for the management of osteoarthritis of the knee. Conventional techniques utilizing manual instrumentation (MI) make use of intramedullary femoral guides and either extramedullary or intramedullary tibial guides. While MI techniques can achieve excellent results in the majority of patients, those with ipsilateral hardware, post-traumatic deformity or abnormal anatomy may be technically more challenging, resulting in poorer outcomes. Computer-assisted navigation (CAN) is an alternative that utilizes fixed trackers and anatomic registration points, foregoing the need for intramedullary guides. This technique has been shown to yield excellent results including superior alignment outcomes compared to MI with fewer outliers. However, studies report a high learning curve, increased expenses and increased operative times. As a result, few surgeons are trained and comfortable utilizing CAN. Patient-specific instrumentation is an alternative innovation for total knee arthroplasty. Custom guide blocks are fabricated based on a patient's unique anatomy, allowing for the benefits of CAN but without the increased operative times or the high learning curve. In this study we sought to evaluate the accuracy of PSI techniques in patients with previous ipsilateral hardware of the femur.

Methods

After reviewing our database of 300 PSI total knee arthroplasty patients, 16 were identified (10 male, 6 female) using the Zimmer NexGen Patient Specific Instrumentation System. Fourteen patients included in the study had a preexisting total hip arthroplasty on the ipsilateral side [Figure 1], 1 had a sliding hip screw, and 1 patient had a cephalomedullary nail. Postoperative mechanical axis alignment measurements were performed using plain long-standing radiographs [Figure 2]. The American Knee Society Score was used to evaluate clinical outcomes postoperatively.


Simon Talbot John Bartlett Rachel Zordan Pandelis Dimitriou Michael Mullen Ross Radic

Purpose

Femoral component malrotation is a common cause for persisting symptoms and revision following total knee arthroplasty (TKA). There is ongoing debate about the most appropriate use of femoral landmarks to determine rotation. The Sulcus Line (SL, See Figure 1) is a three-dimensional curve produced from multiple points along the trochlear groove. Whiteside's Line, also known as the anteroposterior axis (APA), is derived from single anterior and posterior points. The purposes of the three studies presented are to i) assess the SL in a large clinical series, ii) demonstrate the effect of parallax error on rotational landmarks, and iii) assess the accuracy of a device which transfers a geometrically corrected SL onto the distal cut surface of the femur.

Methods

The first study assessed the SL using a large, single surgeon series of consecutive patients (n=200) undergoing primary TKA. The postoperative CT scans of patients were examined to determine the final rotational alignment of the femoral component. In the second study measurements were taken in a series of 3DCT reconstructions of osteoarthritic knees (n=44) comparing the rotational landmarks measured along either the mechanical axis or the coronal axis of the trochlear groove. The third study assessed the accuracy of a novel trochlear alignment guide (TAG) using cadavers (n=10)


Hiroshi Tamai

Purpose

The purpose of this study was to investigate the rate of return to work after total knee arthroplasty (TKA).

Materials and Methods

105 knees of 80 cases were tested after TKA surgery. 18 knees of 14 cases were men and 87 knees of 66 cases were women. The average age at the time of surgery was 71.5 years, and the average postoperative observation period was 25.5 months. All patients were with osteoarthritis of the knee. The use models were Hi-tech Knee II (Nakashima Medical, Okayama, Japan) CR type 99 knees and PS type 6 knees. The rate of return to work after surgery and employment rate of before and after surgery were examined for all cases. In addition,[1]age at surgery [2]ROM [3]JKOM score(Akai 2006) [4]Knee Society score (KSS Insall 1989) were examined in each case, and found the factors influenced on employment rate after TKA. The occupation was classified using major group of the International Standard Classification of Occupations (ISCO-08) defined by International Labour Organization (ILO) on 2007. Mann-Whitney U test was used for the statistical work.


Tatsuya Tamaki Kazuhiro Oinuma Yoko Miura Hidetaka Higashi Ryutaku Kaneyama Hideaki Shiratsuchi

Background

In total hip arthroplasty (THA), the importance of preserving muscle is widely recognized. It is important to preserve the short external rotator muscles because they contribute to joint stability and prevent postoperative dislocation. However, despite careful capsular release and femoral rasping, damage to the short external rotator muscles may occur. The Optymis Shot Stem preserves more bone and surrounding tissue than does a traditional primary stem. We investigated the usefulness of the stem in terms of the extent of preservation of the tendon attachment on the greater trochanter.

Method

In this study, we enrolled 31 consecutive patients (39 hips; 6 males, 25 females) who underwent THA. Simultaneous bilateral THA was performed in 8 patients. The patients’ mean age was 56.1 years. Diagnoses included developmental dysplasia in 35 hips (Crowe group 1: 31 hips, group 2: 4 hips), and sequel of Perthes disease in 4 hips. All THAs were performed via the direct anterior approach without traction tables. The femoral procedure was performed with the hip hyperextended, and posterior capsular release was performed if the femoral procedure became technically difficult. We compared the following among patients: the operative time, intraoperative blood loss, length of hospital stay, rate of posterior capsular release, postoperative radiographic findings, WOMAC score before and after surgery, and any complications.


Tatsuya Tamaki Kazuaki Matsumoto Kazuhiro Oinuma Yoko Miura Hidetaka Higashi Ryutaku Kaneyama Hideaki Shiratsuchi

Background

In total hip arthroplasty (THA), the importance of preserving muscles is widely recognized; therefore, muscle-sparing approaches are widely used. Recently, we reported that there are bony impressions, that we called the obturator attachment (OA), on the greater trochanter that indicate the insertions of the short external rotator tendons. In this study, we used a three-dimensional (3-D) template to evaluate damage to the insertions of the short external rotator muscles during a femoral procedure.

Methods

We investigated 12 hips in 10 patients who underwent THA. Preoperative CT imaging of the hip was performed, and 3-D reconstruction of the greater trochanter was used to visualize the bony impressions that indicate the insertions of the obturator internus and externus muscles (Fig 1A). We performed preoperative 3-D templating of two different femoral prosthesis (flat tapered-wedge stem: J-Taper, cylindrical straight stem: PerFix910) and then evaluated the extent of damage to the OA during the stem placement (Fig 1B, 1C). The extent of damage to the OA was classified using the following scale: grade 0, no damage of the insertion area; grade 1, less than 1/3; grade 2, equal to or more than 1/3–2/3; grade 3, equal to or more than 2/3; grade 4, complete.


Yasunobu Tamaki Hiroyuki Kawaji Masaji Ishii Katsuyuki Dairaku Michiaki Takagi

INTRODUCTION

Venous thromboembolism (VTE), especially, deep vein thrombosis (DVT) in lower extremities, often seriously combined with pulmonary embolism (PE), is a major and critical complication after total hip arthroplasty (THA). For better disgonsis of VTEs, D-dimer test is one of the useful methods. The aim of this study was to evaluate the efficacy of D-dimer levels before THA.

MATERIALS AND METHODS

Medical records of patients with osteoarthritis who received THA between April 2009 and March 2010 were reviewed. Value of D-dimer at preoperative day 1, postoperative day 3 and 14 was examined in those patients. D-dimer levels were examined by Latex Immunity Nephelometry Measurement Method and the Kit (Sysmex Corporation, Kobe, Japan). A total of 327 patients with D-dimer values were examined. The values D-dimer of the available patients were under 1.0 μg/ml. Ninety-nine patients (30%) had a high D-dimer level. DVT was diagnosed by doppler ultrasonography at preoperative day 1, postoperative day 3 and 14. The sensitivity and specificity of D-dimer in different cutoffs were verified by Receiver Operating Characteristic (ROC) curve. The ROC curve was constructed to describe the relationship between the sensitivity and the false positive rate for different values of D-dimer to patients suspected of VTEs. The study protocol was approved by the institutional ethics committee.


Masashi Tamaki Tetsuya Tomita Takashi Miyamoto Keiji Iwamoto Takafumi Ueda Kazuomi Sugamoto

Introduction

The deformity in osteoarthritis (OA) of the knee has been evaluated mainly in the frontal plane two dimensional X-ray using femorotibial angle. Although the presence of underlying rotational deformity in the varus knee and coexisting hip abnormality in the valgus knee have been suggested, three dimensional (3D) deformities in the varus and valgus knee were still unknown. We evaluated the 3D deformities of the varus and valgus knee using 3D bone models.

Methods

Preoperative computed tomography (CT) scans of twenty seven OA knees (fifteen varus and twelve valgus) undergoing total knee arthroplasty were assessed in this study. CT scans of each patient's femur and tibia, with a 2 mm interval, obtained before surgery. We created the 3D digital model of the femur and tibia using visualization and modeling software developed in our institution. The femoral coordinate system was calculated by the 3D mechanical axis and clinical transepicondylar axis and the tibial coordinate system was calculated by the 3D mechanical axis and Akagi's line. The 3D deformities of the knee were determined by the relative position of the femorotibial coordinate system, and described by the tibial position relative to the femur. The anteversion of the femoral neck were calculated to evaluate the relationship between the valgus knee and hip region.


Kohei Murase Shun Tamamura Shinro Takai Sadami Tsutsumi Eiichi Tanaka

The interface condition between the prosthesis and the bone tissue must play important roles during dynamic loading transfer through the knee joint. In this study, the three- dimensional impact finite element (FE) simulations were performed to investigate the impact stress propagation.

The FE models of a totally replaced knee joint were constructed with the high shape fidelity. The models included the cortical and cancellous bone, articular cartilage, bone marrow, and the artificial femoral and tibial components. The artificial components were set to the femoral and tibial contact area. The FE meshes had 7251 nodal points and 5547 hexahedral elements (Figure 1).

The interfacial condition between the artificial component had two kind of contact situations, bonding situation and no-bonding ones. In the bonding situation, the interface between the artificial components and the cancellous bone had fully fixations. The no-bonding allowed the tie-breaking of each other although the interface had the high coefficient of friction. The three kind of the impact loading (1, 5, and 10kgW) were applied from the proximal femur to the distal side of tibia.

In the FE simulations, the impact stress propagated to the tibia through the TKR joint components during several milliseconds. On the interfacial surface at the cancellous side of the proximal tibia, the difference in the stress distribution was observed according to the contact situation of the TKR component (Figure 2). The fully fixation (tied to each other) model showed the high compressive stress on the interface. On the other hand, in the no-bonding model, the compressive stress distributed discontinuously and the high compressive stress was observed only in the hole area and edge of the tibial component during the impact loading. In previous research, the cancellous bone had important roles for the load transmission inside the joint especially under the impact loading condition. However, this study indicated that the stress shielding was caused by the imperfect bonding at the interface. More consideration of the interface situation between the bone and component is required to keep stability for impact loading.


Chiaki Tanaka Youngwoo Kim Hiroshi Kanoe

Between 1993 and 2003, 67 consecutive revision total hip arthroplasties were performed in 65 patients, including 52 women and 13 men, using hydroxyapatite (HA) granules supported by a Kerboull-type reinforcement acetabular device. The average age at the time of index surgery was 68.6 years. The Acetabular bone loss according to the American Academy of Orthopaedic Surgeons (AAOS) system was type II for 7 hips, type III for 58 hips, and type IV for one hip. The Kerboull-type acetabular reinforcement device used was Kerboull Cross Plate in 18 hips and KT Plate in 49 hips. HA granules of sizes 0.9 to1.2 mm (G4) and 3.0–5.0 mm (G6) were mixed in a ratio of 1:1. Autografts were used to reconstruct the major segmental defects in 7 hips. At the time of this study 30 hips were lost of follow-up. Among 30 hips 22 hips were lost of follow-up because of the death of the patients. The remaining 37 hips were examined clinically and radiologically. The mean follow-up period of the series was 12.8 years. Complications were examined and clinical evaluation was done using Japanese Orthopaedic Association (JOA) hip score. The criterion for loosening of the acetabular component was cup migration exceeding 3 mm or angular rotation exceeding 3 degrees or breakage of the device. Among the entire series of 67 hips postoperative complications included dislocation in 3 hips, infection in 2 hips and revision in 4 hips. Two hips were revised for loosening and the other two hips were revised for infection. The JOA hip score increased from a mean value of 48.0 preoperatively to 76.8 at the last follow-up. Radiologically 5 hips were loose. Two hips among them were revised. Survival rate of the acetabular component at 10 years was 97.1% using acetabular revision for loosening as the end point and 90.6% using radiological loosening as the end point. Acetabular reconstruction with HA granules and a Kerboull-type acetabular device provided satisfactory clinical and radiographic results at 12.8 post-operative years.


Kensei Tanaka Kou Hasegawa Rina Sakai Kiyoshi Mabuchi

Introduction

Post cam structure, which is the main structure of posterior-stabilized design (PS), is useful to realize the intrinsic stability of a knee prosthesis replaced for a case with the severe degeneration. A large size post might, however, shorten the range of knee motion. On the other hand, retrieval studies sometimes reveal the ultrahigh molecular weight polyethylene (UHMWPE) deformation or severe failure of the tibial post of PS knee. Strength of a tibial post of available design is obviously insufficient to prevent the severe deformation. Therefore, minimally required size of the post should be clarified for polyethylene inserts. In the present study, we performed finite element (FE) analysis assumed the mechanical conditions of a tibial post in a PS knee and aimed to design criterion of a post of polyethylene insert of a knee prosthesis.

Method

The shape of one commercially available knee prosthesis was referred as a posterior-stabilized knee prosthesis. The contour of the metallic femoral component was traced and digitized by hand. The contour of the UHMWPE insert was digitized by a micro computed tomography apparatus. Three dimensional finite elements were generated by a modeling software (Simpleware, Ltd. UK) as total 83000 four-noded tetrahedral elements. The bottom of the tibial insert was fully constrained. Load on femoral component was assumed to realize the tibial post impingement under several kinds of knee motions. Posterior load 100 N or 500N at the 10 degree hyperextension, anterior load 500N or 1000N during 120 degree flexion were applied (Fig. 1). The software of FE analysis was LS-DYNA ver.971 (Livemore Software Technology Corp. USA). The hardware was Endeaver Pro-4500 (EPSON Corp. Japan). The distributed values of von Mises stress and plastic strain of the tibial post were shown as the results of the analysis.


Aree Tanavalee Sarit Hongvilai Srihatach Ngarmukos Natdhadej Mekrungcharas Pongporn Prateeptongkum Yongsak Wangroongsub

Background

Most of contemporary total knee systems address on improving of range of motion and bearing materials. Although new total knee designs in most systems accommodated the knee morphology according to gender differences, reestablishing of the same anterior offset of the distal femur during total knee arthroplasty (TKA) has not been well addressed. Furthermore, in most total knee systems, the anterior offset of the femoral component is constant regardless of the increment of the femoral size. We hypothesized that change of the anterior offset of the distal femur during TKA might affect the quadriceps strength and immediate clinical outcomes which may result in improved design of the future femoral component.

Purpose

To evaluate the peak quadriceps strength and immediate clinical outcomes related to the change of anterior offset of the distal femur during TKA.


Hao Tang Yixin Zhou Dejin Yang Shengjie Guo Hong Chen Zhihua Wang

Background

Soft tissue tension and intra-articular pressure distribution plays a crucial role in postoperative function and survivorship of TKA prosthesis. Although posterior stabilized (PS) and cruciate retaining (CR) knees have both been successful in relieving pain and restore function, it is reported that the joint gaps were significantly distinct between the two designs during flexion. The aim of this study is to find out what is the difference in intra-articular pressure distribution between PS and CR knees.

Methods

We prospectively included 45 consecutive patients (50 knees) scheduled for total knee arthroplasty between August, 2013 and April, 2014 in our hospital. 23 patients (25 osteoarthritic knees) received a Genesis II CR TKA (Smith & Nephew, Memphis, USA), and the other 22 patients (25 osteoarthritic knees) received Genesis II PS TKA (Smith & Nephew, Memphis, USA). During operation, after the bone osteotomy and soft tissue balance were completed, we measured and compared the intra-articular pressure distribution at 0°, 30°, 45°, 60°, 90°, and 120° flexion with a previously validated “Wireless Force Measurement System (WFMS)”. Joint gaps were measured at extension and 90° flexion. The soft tissue was not considered balanced until the medial and lateral joint gap difference ≤ 2mm at extension and 90° flexion. There are no significant differences in age, gender, BMI, varus angle and flexion deformity, and preoperative range of motion between the two groups. The medial-lateral pressure distribution and total pressure were compared at different angles between CR and PS knees.


Satoshi Terada Kunio Nakane Takhiro Yamamoto Shigeo Niwa

In performing posterior cruciate ligament- retaining total knee arthroplasty (CR-TKA), the original surgical instrument was devised to obtain the range of motion and stability of the knee joint adequate for daily life of Japanese people. We have presumed the tentative joint line as intercondylar notch point of the distal femur, and performed surgery using surface replacement to resect metal width of the femoral component for the distal femur by setting the knee to the original position based on understanding of the shape of anterior curvature of the distal femur in Japanese people in case of implanting the femoral component. In order to obtain stability of the knee, we have minimally released the soft tissue and resected the anterior cruciate ligament (ACL), whereas completely preserved the posterior cruciate ligament (PCL) and maintained physiological ligament balance of the knee joint by resecting the medial condyle of the tibia (genu varus). Our surgical procedure enabled deep flexion knee (knee embracing) greater than 145 degrees in 9.7% and also allowed Japanese sitting in three different designs of total knee joints.


Emmanuel Thienpont Pierre-Emmanuel Schwab Jean Paul Forthomme Olivier Cornu

Introduction

Patient satisfaction after total hip arthroplasty (THA) has been reported to be significantly better than after total knee arthroplasty (TKA). The same has been observed for the capacity to forget during daily life activities about the operated joint. Recently a new patient reported outcome score, the Forgotten Joint Score (FJS-12) a twelve item questionaire, has been used to evaluate postoperative outcome in joint arthroplasty. A better FJS-12 score was measured in THA than in TKA objectivating the intuitive feeling that the joint was more forgotten in THA than in TKA.

Hypothesis

A higher preoperative FJS-12 score is the reason for a higher postoperative FJS-12 score in THA compared to TKA


Emmanuel Thienpont Jess Lonner

Introduction

Patellofemoral arthroplasty (PFA) can give excellent results in well-selected patients. Axial alignment has been extensively studied in this type of surgery. However because there is no distal femoral cut, coronal alignment in PFA is less well known. The position of the patellofemoral component decides the varus or valgus alignment of the implant.

Hypothesis

Coronal alignment in PFA (PFJ-Gender, Zimmer, Warsaw, US) is determined by the anterior condylar anatomy and features an important variance influencing coronal alignment.


Kim Bland Leslie Thomas Kristi Osteen Tamara Huff Beau Bergeron George Chimento Mark S. Meyer

Introduction

Knee osteoarthritis is a leading cause of disability around the world. Traditionally, total knee arthroplasty (TKA) is the gold standard treatment; however, unicompartmental knee arthroplasty (UKA) has emerged as a less-invasive alternative to TKA. Patients with UKAs participate earlier with physical therapy (PT), have decreased complications, and faster discharges (1, 2). As UKA has evolved, so has computer navigation and robotic technology. The Robotic Assisted UKA combines the less invasive approach of the UKA with accurate and reproducible alignment offered by a robotic interface (3)(Figure1).

A key part of a patient's satisfaction is perioperative pain control. Femoral nerve blocks (FNB) are commonly performed to provide analgesia, though they cause quadriceps weakness which limits PT (4). An alternative is the adductor canal block (ACB) which provides analgesia while limiting quadriceps weakness (4). The adductor canal is an aponeurotic structure in the middle third of the thigh containing the femoral artery and vein, and several nerves innervating the knee joint including the saphenous nerve, nerve to the vastus medialis, medial femoral cutaneous nerve, posterior branch and occasionally the anterior branch of the obturator nerve (5).

In a multi-modal approach with Orthopedic Surgery, Regional Anesthesia, and PT departments, an early goal directed plan of care was developed to study ACB in UKA with a focus on analgesia effectiveness and PT compliance rates.

Methods

Following IRB approval, we performed a case series including 29 patients who received a single shot ACB.

Primary outcomes were distance walked with PT on postoperative day (POD) 0 and 1 and discharge day. Our secondary outcomes included Visual Analog Scale (VAS) scores in the post-anesthesia care unit (PACU), 8 and 24 hours postoperatively and oral morphine equivalents required for breakthrough pain.


Jeremy Latham Dafydd Locker Simon Tilley

Aims

This retrospective study aimed to determine the causes of in-hospital death after Neck of Femur (NOF) fracture in Southampton General Hospital (SGH) over a 6 year period, comparing the clinical cause of death with findings at post-mortem. A previous study showed discrepancies between pre-mortem clinical diagnosis and autopsy findings after in-hospital deaths in SGH.

Methods

The study included all patients who died in SGH after NOF fracture from 2007–2013. Case notes were reviewed to determine the pre-mortem clinical diagnosis and compared with the autopsy findings to analyse major and minor discrepancies. Data were also analysed from the period 1997–2003 in order to compare the causes of death.


John Timperley

Introduction

Impaction bone grafting for reconstitution of acetabular bone stock in revision hip surgery has been used for nearly 30 years. We report results in a group of patients upon whom data has been collected prospectively with a minimum ten year follow-up.

Material and Methods

Acetabular impaction grafting was performed in 305 hips in 293 patients revised for aseptic loosening between 1995 and 2001. In this series 33% of cases required stainless steel meshes to reconstruct medial wall or rim defects prior to graft impaction. These meshes were the the only implants used for this purpose in this series. All Paprosky grades of defect were included. Clinical and radiographic outcomes were collected in surviving patients at a minimum of 10 years following the index operation; mean follow-up was 12.4 years (SD 1.5; range 10.0–16.0).


John Timperley Matthew Wilson

Acetabular impaction grafting (AIG) for the reconstruction of acetabular defects in total hip arthroplasty has the potential to recreate anatomy whilst also allowing the restoration of bone stock. The incorporation of impacted, morcellised bone graft has been demonstrated in histological studies and is a well established technique in revision hip surgery where there is loss of bone stock. We have studied our results of fullAIG when used in primary total hip arthroplasty, with particular emphasis on the results of AIG in cavitary and segmental defects.

Between 1995 and 2003, 129 cemented primary THAs were performed using full acetabular impaction grafting to reconstruct acetabular deficiencies. These were classified as cavitary in 74 and segmental in 55 hips. Eighty-one patients were reviewed at mean 9.1 (6.2–14.3) years post-operatively. There were seven acetabular component revisions due to aseptic loosening, and a further 11 cases that had migrated »5 mm or tilted »5° on radiological review — ten of which reported no symptoms. Kaplan–Meier analysis of revisions for aseptic loosening demonstrates 100% survival at nine years for cavitary defects compared to 82.6% for segmental defects. Our results suggest that the medium-term survival of this technique is excellent when used for purely cavitary defects but less predictable when used with large rim meshes in segmental defects.


John Timperley Sarah Whitehouse

Mortality following hip arthroplasty is affected by a large number of confounding variables each of which must be considered to enable valid interpretation.

The aim of this study was to establish whether it is possible to determine a true cause-and-effect relationship between the risk of mortality and data that are routinely collected by the NJR and to establish the degree to which variation in the mortality rate could be explained by each variable.

Relevant variables available from the 2011 NJR data setwere included in a Cox model.

We carried out two analyses:

Firstly, we conducted an analysis of data collected from the NJR data set used in preparation of the NJR's 8th Annual Report (2011) looking for an association between the variables collected and the risk of mortality.

Secondly, as social deprivation is also known to influence mortalityrates but is not routinely collected as part of the NJR data set, a further analysis was performed which included social deprivation data derived from partial postcodes.

Mortality rates in hip arthroplasty patients were lower than in the age matched population across all hip types. Age at surgery, ASA grade, diagnosis, gender, provider type, hip type and lead surgeon grade all had a significant effect on mortality. Schemper's statistic showed that only 18.98% of the variation in mortality was explained by the variables available in the NJR data set.

It is inappropriate to use Registry data to study an outcome affected by a multitude of confounding variables when these cannot be adequately accounted for in the available data set.


Eita Togashi Shigenobu Fukushima Hirobumi Sugawara Atsushi Narita Michiaki Takagi

Various types of tibial alignment guides exist, the results in performing the tibial resection in total knee arthroplasty (TKA) are more or less than we desired. In addition, it is difficult to estimate the accuracy of tibial component alignment with radiograph because it is difficult to get true frontal and lateral view. In this study, we use new tibial alignment guide and estimate tibial component alignment by using postoperative CT scan.

30 knees underwent TKA using an accelerometer-based, portable navigation device (KneeAlign 2) and postoperative CT scans were obtained. Postoperative CT scans of the lower limbs analysed by 3D digital template system (Athena), demonstrated that 96.6% of the tibial components were placed within 90°± 2°to the mechanical axis in the coronal plane, and 96.6% of the components were placed within 3°± 2°to the mechanical axis in the sagittal plane.

As a result of this study, an accelerometer-based, portable navigation device can expect to decrease outliers in tibial component alignment.


Shunichi Toki Hiroshi Mikami Keizo Wada Koichi Sairyo

Introduction

Recently, there are increasing literatures of the in vivo kinematics of total knee arthroplasty (TKA). Those previous studies have been reported in regard of either intra-operative kinematics or post-operative kinematics. However, the direct correlation between intra- and post-operative kinematics of TKA has not been revealed. There are no evidences that intra-operative kinematics can lead to post-operative kinematics.

Purpose

The purpose of this study is to verify the direct correlation between intra- and post-operative kinematics of TKA.


Kazuo Tomizawa Kazuya Tamai Miwa Akutsu Yuichiro Yano Katsuhisa Yoshikawa Takuya Sukegawa Yuji Yamaguchi Hiroshi Taneichi

Objectives

Our principle is to bring the socket back to the true acetabulum position. A large structural bone graft is required for severe subluxation. We obtained good long-term results with structural bone grafts. It is necessary to evaluate the bone graft 3 dimensionally, not 2 dimensionally.

M and M

We evaluated our 305 primary THAs operated from April 2010 to Mar 2014. Structural bone grafts were utilized on the acetabulum in 39 cases (12.8%).

We measured the CE angle on post-operative plain coronal x-rays. 3D-CT evaluation was carried out on the cases with CE angles of 0 degrees or less.

We checked the position of the graft and see how much surface area the graft occupies of the total area that receives the load.


Marty Trabish

Hypothesis

The use of cartilage compensated virtual standing CT images for pre surgical planning improves the reliability of preoperative planning.

Materials and Method

Sampling included in this study were > 62 years of age (mean age 58.17 yrs ±3.54 yrs, range 55–62) with symptomatic isolated medial osteoarthritis, genu varum (mean varus 5.6°±2.6 °, range 2.1°–8.6°), good range of motion (flexion > 90° and flexion contracture < 10°) and with minimal ligamentous instability. All subjects had obtained a pre-op CT scan, MRI scan and weight-bearing long bone x ray. Post-op CT and long standing x-rays were taken prior to hospital discharge.

A virtual software suite (HTO-OP3D, Zapalign Inc, Seoul, Korea) was utilised to determine an optimal osteotomy site, hinge location and a gap necessary to achieve the targeted virtual passing point.

Prerequisite to performing the necessary calculations a virtual standing pose for each patient specific bone models was created using the following steps.

To transfer the pre surgical plan intra-operatively, a customised alignment jig was manufactured


Soichi Tsuji

Objection

Multimodal local periarticular injection can be effective for pain management after total knee arthroplasty. We have investigated to get the similar results after total hip arthropasty.

Methods

Sixty patients undergoing total hip arthroplasy were divided to two groups. One were with multimodal local periarticular injection(Group M) and the other were with single intraarticular injection Group C, conventional method. We injected a “cocktail” agents into the soft tissue (capsule, synovium, muscle, subcutaneous fat tissue, skin) around the implants. Those were contained Morphinesulfate, Ropivacaine, Adrenaline, Methylpredonisolone, Ketoprofen, and Normal saline. We compared the VAS(at rest and during walking), the duration of the mobilization and active SLR, and any complicaions.


Koji Tsuji Kazuo Hirakawa Scott Banks

Introduction

It is important to measure 2-dimensional (2D) polyethylene wear in total hip arthroplasty (THA) accurately in order to estimate value of wear performance. However, wear vector direction is usually defined in a coordinate system specific manner, which sometimes leads to confusion and makes it difficult to compare measures between techniques. We systematically evaluated the influence of four different coordinate system definitions for the measurement of 2D wear in acetabular cups form radiographs.

Materials and Methods

We performed 2D wear measurement of 152 hips that underwent THA using a 26mm CoCr femoral head with the same design of cementless acetabular shell between September 2003 and March 2005. All hips received either a CPE liner (76 hips, gamma sterilized at 25 kGy) or a XLPE liner (76hips, 10Mrad e-beam irradiation, EtO sterilized) randomly during the surgery. The average follow-up was 81.6±8.2 months.

Supine AP radiographs obtained postoperatively at 6 months and final follow-up were assessed for each femoral head penetration and angle using Roman v1.70 software (http://www.cookedbits.co.uk/roman/). The wear magnitude and angle between the two follow-ups was calculated using four coordinate system definitions:

#1; the line tangent to both ischiums was defined as 0 degrees, with wear directed medially defined as positive and wear detected laterally defined as negative. (Martell; JBJS Vol79-A No11 p1635–41)

#2; wear directed toward the liner (Zone 1 and Zone 2) defined as positive and away from it as negative (Zone 3 and Zone 4). (Wan; CORR No 449 p267–224)

#3; wear vector magnitude angle ranging between 0 and 360, starting from the medial part of the line (x axis). (Greedink; JBJS Vol90-B p839–46)

#4; wear vector between 0 and 180, directed towards the liner, was identical with coordinate #3. The vector between 180 and 360, directed away from the liner, was analyzed into the positive cosine magnitude. (Modified #3)


Takashi Tsujimoto Yoshichika Hashimoto Wataru Ando Tsuyoshi Koyama Kengo Yamamoto Kenji Ohzono

INTRODUCTION

The concept of anatomical stam is fit-and-fill in the proximity of the femur and to expect wall fixation, following to reduce thigh pain and stress shielding. Although the femoral medullary form and size are different in each races. CentPillar TMZF stem (stryker ®) is anatomical stem designed based on computer-tomography of Japanese femurs. The purpose of this study was to evaluate clinical and radiographic outcomes of CentPillar TMZF stem at a mean of 3.6 years postoperatively.

METHODS

We asseses the results of 98 primary total hip arthroplasty (THA) performed using a CentPillar TMZF stem in 91 Japanese patients (4 males, 94 females) undergoing surgery between August 2007 and June 2011, the mean age at the time of surgery was 62.0 (41–81) years old. The Diagnosis were osteoarthritis (OA) in 91 hips, rapidly destructive coxopathy (RDC) in 4 hips, rheumatoid arthritis (RA) in 3 hips. Clinical and radiographic assessments were performed for every patient for every follow up using Japan Orthopaedic Association (JOA) Score, thigh pain, revision surgery and complications. Radiographic assessments were including stem alignment on anteroposterior radiograph, stress shielding, bone remodeling, radiolucent line, osteolysis, loosening and subsidence.


Sachiyuki Tsukada Motohiro Wakui Minako Ooiwa Kaoru Tsurumaki Akiho Hoshino

Background

Evidence from recent trials has supported the efficacy of periarticular analgesic injection for pain control following total knee arthroplasty (TKA). However, no randomized controlled trial has compared the efficacy of periarticular analgesic injection with that of other regimens for simultaneous bilateral TKA.

Methods

We conducted a randomized controlled trial in which patients scheduled for simultaneous bilateral TKA were randomly assigned to receive periarticular analgesic injection or epidural analgesia. In the periarticular analgesic injection group, the injection contained 7.5 mg/ml ropivacaine 40 ml, 10 mg/ml morphine hydrochloride hydrate 1.0 ml, 1.0 mg/ml epinephrine 0.6 ml, methylprednisolone 80 mg, and ketoprofen 50 mg. These agents were mixed with normal saline to a combined volume of 120 ml. The 60 ml of the cocktail was injected into each knee. In the epidural analgesia group, the catheter was placed at the L2–3 or L3–4 level, and connected to an infusion pump delivering continuous infusion (flow rate: 4 ml/h) of 100 ml of 2 mg/ml ropivacaine plus 1.0 ml of 10 mg/ml morphine hydrochloride hydrate. Surgery was managed under spinal anaesthesia. Surgical techniques and postoperative medication protocols were identical in both groups. The primary endpoint was postoperative pain at rest, quantified as the area under the curve (AUC) of the score on a visual analogue scale.


Rama Ramakrishnan Masaaki Tsurumoto James D'Antonio

Background

A first generation once annealed highly crosslinked polyethylene (HXLPE) was introduced in 1998. At 8 years it was reported to have a 78% reduction in wear compared with conventional polyethylene and no osteolysis. However, concerns regarding the long-term performance and oxidative resistance of this annealed material exist because of the presence of free radicals.

Questions/purposes

We therefore addressed the following questions: (1) Does the improvement in wear observed at earlier follow-up continue out to 15 years? (2) What is the incidence of osteolysis in this group of patients?


Rama Ramakrishnan Masaaki Tsurumoto Arthur L Malkani

Introduction

Technological advances in the processing of polyethylene have led to improved survivorship of total hip arthroplasty. The purpose of this study was to determine if a second generation highly cross-linked polyethylene could improve upon wear rates compared to conventional and first generation cross-linked polyethylene in patients undergoing primary total hip arthroplasty.

Methods

Linear and volumetric wear rates of a second generation highly cross-linked polyethylene were evaluated following primary total hip arthroplasty. There were 44 patients with an average age of 68.6 years and mean follow-up of 5.3 years. Patients were evaluated at six weeks, one, two and five years. Wear rates were determined from digitized AP Pelvis radiograph by an independent observer using Martell's software. Acetabular inclination and femoral head size were also evaluated to determine variability in wear rates.


Francesco Mattia Uboldi Paolo Ferrua Stefano Pasqualotto Giulia Carimati Pietro Zedde Massimo Berruto

INTRODUCTION

Osteochondral lesions of the knee are relatively common both in young and senior population. The very disabling clinical symptoms, in association to the scarce regenerative capacity of the articular cartilage and the increased risk of developing a secondary osteoarthritis make an effective treatment mandatory.

MATERIALS AND METHODS

From December 2008 to January 2013, 34 patients (35 knees), 24 males and 10 females (mean age 36.2 years range 14–66) underwent implant of Maioregen® (Finceramica Faenza S.P.A, Italy) biomimetic osteochondral scaffold. In 17 cases the osteochondral lesion was cause by an osteochondritis dissecans (acute or sequela), in 13 cases by a spontaneous osteonecrosis and in 4 cases the etiology was traumatic. Patients were evaluated with subjective IKDC and Tegner Lysholm scores, VAS and Tegner Activity Scale before surgery and at regular follow up (mean follow up 38.4 months, range 13 months max 63 months).


Keisuke Uemura Masaki Takao Takashi Sakai Takashi Nishii Nobuhiko Sugano

Introduction

Support cages are often used for reconstruction of acetabular bone defects in revision total hip arthroplasty. A Burch-Schneider cage is one of the most reliable systems that has shown good clinical results. It has an ischial flange and an iliac plate for screw fixation to the ilium. It is sometimes necessary to bend the flange or the plate to fit the shape of the peri-acetabulum. However, the frequency, indications, and characteristics of bending the flange or plate have not been reported. To clarify them, a simulation study was conducted.

Materials and methods

Twenty-five cases with acetabular bone defects of Paprosky type 2, 3, or 4 were the subjects of this study. A 3D template surgical simulation was conducted using 3D surface models of the Burch-Schneider cage and acetabulum. The size of the cage was determined by the size of the cavitary bone defect. Placement of the cage was performed in two ways. One was the iliac plate fitting method, in which fitting of the iliac plate to the ilium was performed first, followed by bending of the ischial flange to keep the flange in the center of the ischium. When bending of the flange was needed, it was bent at the base. The other method was the ischial flange fitting method, in which the ischial flange was inserted from the center of the ischium, followed by bending of the iliac flange to adapt to the ilium. When bending of the plate was needed, it was bent at the base. In both methods, the direction and angle of bending were measured.


Mizuho Ueshima Nozomu Yoshimura Masashi Otsuki Naoya Hatano Nobuya Tamura Yasuhiko Iwasaki Kazuhiko Ishihara Yasushi Tamada Katsura Kojima Yusuke Kambe Manabu Akahane Takamasa Shimizu Yasuhito Tanaka Naohide Tomita

Introduction

It is essential to investigate the tribological maturation of tissue-engineered cartilage that is to be used in medical applications. The frictional performances of tissue engineered cartilage have been measured using flat counter surfaces such as stainless steel, glass or ceramics. However, the measured friction performances were significantly inferior to those of natural cartilage, likely because of cartilage adhesion to the counter surface. Tamura et al. reported that a poly (2- methacryloyloxyethyl phosphoryl-choline (MPC)) grafted surface shows low friction coefficient against cartilage without the adhesion to be equivalent to those for natural cartilage-on-cartilage friction. [1]

On the other hand, Yamamoto et al. reported that applying a relative sliding movement had a potential to alter the expression of tribological function of regenerated cartilage of chondrocytes. [2] In this paper, the effects of the relative sliding movement on the expression of bone marrow stromal cells (BMSC)s were investigated using the poly(MPC) grafted surface as a counter surface.

Material and methods

BMSCs seeded onto fibroin sponge scaffolds were cultured by using the stirring chamber system (Figure 1), which can apply a relative tribological movement to the surface of the specimens. Three culture conditions were applied (dynamic in stirring chamber as frequency as 40 min [D1], as 40 sec [D2] and static in stirring chamber group [S]). The specimens were set into stirrer on a poly(MPC) grafted surface (MPC polymer coated surface, SANSYO).

As a counter surface in friction tests, the poly(MPC) grafted surface was prepared by atom transfer radical polymerization, and the regenerated cartilage was prepared by seeding 5×105 cells (BMSCs from rat bone marrow) onto fibroin sponge scaffolds (8 mm diameter and 1 mm thickness) and by 14 days culture.


Keita Uetsuki Yuta Osaka Naohide Tomita

Introduction

Dl-α-Tocopherol (VE)-blended non-crosslinked UHMWPE has been developed as a bearing surface material for knee prostheses due to the radical scavenging capabilities of vitamin E and has demonstrated a low wear rate in knee simulator testing [1,2]. In previous our study, VE-blended, crosslinked UHMWPE has demonstrated a low wear rate in hip simulator testing [3, 4]. As the radical scavenging capabilities also reduce the crosslinking degree of the material, multiple dose crosslinking has been investigated. However, these crosslinked UHMWPE materials may have different mechanical properties, as each crosslinking process, especially the annealing condition, is different. Additionally, there is little information about VE-blended, crosslinked UHMWPE with different annealing conditions. In this study, the effect of annealing temperature was investigated with regard to tensile strength, crosslink density, and crystallinity of VE blended, crosslinked UHMWPE.

Method

VE blended samples were manufactured via direct compression molding following the blending of UHMWPE resin powder (GUR1050, Ticona Inc.) with VE (dl-α-tocopherol, Eisai Co. Ltd.) at 0.3wt%. The virgin samples were derived similarly, but without the addition of VE. Both materials underwent crosslinking by irradiation via a 10MeV electron beam at 300kGy and were then heat treated at several temperatures (25, 80, 110, 130 and 150 °C) for 24 hours.

Gel content, which can be interpreted as cross-link density, was determined by measuring the weight of the samples before and after soaking in decahydronaphthalene at 150 °C for twelve days.

Tensile tests were carried out following JIS K 7113, with the cross head speed set at 50 mm/min.

Crystallinity was determined by using DSC and integrating over the enthalpy curve from 80 to 150 °C and normalizing with the enthalpy of melting for 100% crystalline polyethylene.


Saif Ul Islam Muhammad Naghman Choudhry Mohammad Waseem

Introduction

Snapping scapula symptoms occur due to disruption of the smooth gliding motion between scapula and thoracic cage. Patients present with pain in the scapulothoracic area aggravated by overhead and repetitive shoulder movements. It is often associated with audible and palpable crepitus, clicking, crunching, grating or snapping sensation. Open or arthroscopic scapulothoracic surgical treatment is an option when non-operative treatment modalities fail. The aim of our study was to assess the outcome of scapulothoracic arthroscopic treatment in patients with painful snapping scapula.

Methods

Eight patients underwent scapulothoracic arthroscopic treatment for painful snapping scapula. Pre-operatively, all these patients had a trial of conservative treatment modalities for at least 6 months, consisting of activity modification, analgesia and physiotherapy for restoration of normal scapulothoracic kinematics. All patients had a temporary pain relief following a local anaesthetic and steroid injection.

We graded the crepitus from 0 to 3 - 0 being no crepitus, 1 being palpable but not audible crepitus, 2 being soft audible crepitus and 3 being loud crepitus.

Operations were performed with the patients in either prone or semi-prone position. The arm was placed in the “chicken wing” position (arm in full internal rotation with the hand placed on the back), so that the scapula lifted up from the chest wall. Two portals along the medial border of scapula were used for arthroscopy and instrumentation. In two cases a superior portal was also used.

Outcome was assessed by pre and postoperative visual analogue score (VAS) and Oxford Shoulder Score. Pre and postoperative scores were compared using paired t-test. The significance level was set at P <. 05.


Catherine Van Der Straeten Stefaan Van Onsem Rutger Callens Matti Slabbaert Jan Victor

Background

The use of Computed Tomography (CT) as a medical imaging tool has widespread applications in the field of knee surgery. Surgeons use a CT scan in a conventional way during the pre-operative stage, to plan the position of the femoral component in the horizontal plane. In the post-operative stage, the use of a CT scan is a routine tool in the evaluation of failed TKA as rotational malalignment of the femoral component has been determined as a cause of poor clinical outcome after TKA.

Aim

How accurately can we measure the different angles with importance for alignment on a 3D-image in comparison to a standard CT, 2D, image.


Catherine Van Der Straeten Stefaan Van Onsem Jan Victor

Introduction

Total Knee Arthroplasty (TKA) is a proven successful and cost-effective method to relieve pain and improve joint function and quality of life in patients with advanced knee arthritis. However, after a TKA, only 75 to 89% of patients are satisfied. Since patient satisfaction is one of the main objectives of elective orthopaedic surgery, it is important to investigate the reasons for dissatisfaction and develop remedial strategies.

Objectives

The aims of the current project are to investigate patient satisfaction after TKA and establish physical, mental and social determinants of patient satisfaction and overall socio-economic costs associated with unsatisfactory outcome. The global objective is to identify patients most likely to benefit from primary TKA, establish optimal evidence-based indications and timing for TKA, and address the necessity to educate patients preoperatively towards realistic expectations or propose alternative therapies. Based on the results, a composite score for patient selection will be developed using objective and subjective parameters. Cut-off values for acceptable indications for TKA will be proposed.


Catherine Van Der Straeten Bart De Roest Koen De Smet

INTRODUCTION

Systemic levels of metal ions are surrogate markers of in-vivo wear of metal-on-metal hip resurfacings (MoMHRA). The wear-related generation of metal ions is associated with component size and positioning but also with design specific features such as coverage angle, clearance, metallurgy and surface technology.

OBJECTIVES

The objective of the study was to investigate whether a hip resurfacing design (ACCIS) with TiNb engineered bearing surfaces would generate less chromium (Cr) and cobalt (Co) ions during and after the run-in phase of wear and whether Ti ions could be detected indicating wear of the coating.


Catherine Van Der Straeten Bart Doyen Camille Dutordoir Wouter Goedertier Simon Pirard Jan Victor

INTRODUCTION

Meniscal tears are very common and treated surgically by suturing or partial or total meniscectomy. After meniscectomy, the tibiofemoral contact area is decreased whih leads to higher contact stresses associated with clinical symproms and a faster progression of tibiofemoral osteoarthritis. Besides meniscus allograft transplantation, artificial implants have been developed to replace the menisci after meniscectomy.

AIM

We investigated the short- and medium-term clinical results and survivorship of two artificial meniscus implants used as a treatment for post-meniscectomy pain in young to middle-aged patients: the anchored polyurethane degradable Actifit® (2007–2013) and the non-anchored polycarbonate-urethane NUSurface® meniscal implants (2011–2013).


Pieter-Jan Vandekerckhove Matthew Teeter Douglas Naudie James Howard Steven MacDonald Brent Lanting

Summary

The effect of polyethylene wear and lift-off between the tibial and femoral components on the mechanical axis was assessed in primary TKA (Total Knee Arthroplasty) based on retrieval data and full leg radiographs.

Introduction

Controversy exist regarding performing a TKA with component placement in physiologic versus neutral alignment. Some literature indicates good survivorship and superior clinical outcome in undercorrected TKA's for varus osteoarthritic knees. However, other literature indicates decreased survivorship and coronal plane alignment is still one of the contributing factors to wear in total knee arthroplasty (TKA). The two determinants of the intra-articular deformity in TKA arepolyethylene wear and lift-off between the tibial and femoral compartment. The goal of this study was to evaluate the impact of wear and lift-off on the mechanical axis in neutral and varus aligned TKA's.


Pieter-Jan Vandekerckhove Matthew Teeter Douglas Naudie James Howard Steven MacDonald Brent Lanting

Introduction

Coronal plane alignment is one of the contributing factors to polyethylene wear in total knee arthroplasty (TKA). The goal of this study was to evaluate the wear and damage patterns of retrieved tibial polyethylene inserts in relationship to the overall mechanical alignment and to the position of the tibial component.

Materials and methods

Based on full-length radiographs, ninety-five polyethylene inserts retrieved from primary TKA's with a minimum time in-vivo of five years were analysed for wear and damage. Four alignment groups were compared: valgus, neutral, mild varus and moderate varus. Varus and valgus positioning of the tibial component was analysed for damage score for the neutral and varus aligned groups.


Matthew Teeter Brent Lanting Edward Vasarhelyi Todor Ivanov Pieter-Jan Vandekerckhove James Howard Douglas Naudie

Increased modularity of total hip arthroplasty components has occurred, with theoretical advantages and disadvantages. Recent literature indicates the potential for elevated revision rates of modular neck systems and the potential for metallosis and ALVAL (Aseptic Lymphocyte dominated Vasculitis Associated Lesion) formation at the modular neck/stem site. Retrieval analysis of one modular neck implant design including SEM (Scanning Electron Microscopy) assessment was done and correlated to FEA (Finite Element Analysis) as well as clinical features of patient demographics, implant and laboratory analysis. Correlation of the consistent corrosion locations to FEA indicates that the material and design features of this system may result in a biomechanical reason for failure. The stem aspect of the modular neck/stem junction may be at particular risk.


Matthew Teeter Amit Parikh Marc Taylor Pieter-Jan Vandekerckhove Jeff Sprague Douglas Naudie

We sought to determine what dimensional changes occurred from wear testing of a total knee implant, as well as whether any changes developed within the polyethylene subsurface. Three fixed bearing implants underwent wear simulator testing to 6.1 million cycles. Gravimetric analysis and micro-CT scans were performed pre-test, mid-test, and post-test. Wear volume and surface deviations were greater during 0–3.2 million cycles (91±12 mm3) than from 3.2–6.1 million cycles (52±18 mm3). Deviations (wear and creep) occurred across all surfaces of the tibial inserts, including the articular surface, backside surface, sides, and locking mechanism. No subsurface changes were found. The micro-CT results were a useful adjunct to gravimetric analysis, better defining the dimensional changes that occurred with testing and ruling out subsurface fatigue.


Edward Vasarhelyi Rakesh Sondekoppam Vijayashankar Brent Lanting James Howard Kevin Armstrong Sugantha Ganapathy

Introduction

Fast track arthroplasty regimens require preservation of motor power to perform early rehabilitation and ensure early discharge (1). Commonly performed nerve blocks like femoral and Sciatic nerve blocks results in motor weakness thereby interfering with early rehabilitation and may also predispose to patient falls (2, 3). Hence, targeting the terminal branches of the femoral and sciatic nerves around the knee joint under ultrasound is an attractive strategy. The nerve supply of interest for knee analgesia are the terminal branches of the femoral nerve, the genicular branches of the lateral cutaneous nerve of thigh, obturator and sciatic nerves (4).

Methods

We modified the performance of the adductor canal block and combined it with US guided posterior pericapsular injection and lateral femoral cutaneous nerve block to provide analgesia around the knee joint. The femoral artery is first traced under the sartorius muscle until the origin of descending geniculate artery and the block is performed proximal to its origin. A needle is inserted in-plane between the Sartorius and rectus femoris above the fascia lata and 5 ml of 0.5% ropivacaine (LA) is injected to block the intermediate cutaneous nerve of thigh. The needle is then redirected to enter the fascia of Sartorius to deliver an additional 5ml of LA to cover the medial cutaneous nerve of thigh following which it is further advanced till the needle tip is seen to lie adjacent to the femoral artery under the Sartorius to perform the adductor canal block with an additional 15–20 ml of LA to cover nerve to vastus medialis, saphenous nerve and posterior division of the obturator nerve (Fig 1). The lateral cutaneous nerve of thigh is optionally blocked with 10 ml of LA near the anterior superior iliac spine between the origin of Sartorius and tensor fascia lata (Fig 2). The terminal branches of sciatic nerve to the knee joint is blocked by depositing 25 ml of local anesthetic solution between the popliteal artery and femur bone at the level of femoral epicondyles (Fig 3).


Nico Verdonschot Vivian Weerdesteyn Lara Vigneron Michael Damsgaard Robert Sitnik Thomas Feikas Vincenzo Carbone Bart Koopman

INTRODUCTION

The burden of Musculoskeletal (M-S) diseases and prosthetic revision operations is huge and increasing rapidly with the aging population. For patients that require a major surgical intervention, procedures are unsafe, uncertain in outcome and have a high complication rate. The goal of this project is to create an ICT-based patient-specific surgical navigation system that helps the surgeon safely reaching the optimal functional result for the patient and is a user friendly training facility for the surgeons. The purpose of this paper is to demonstrate the advancements in personalized musculoskeletal modeling for patients who require severe reconstructive surgery of the lower extremity.

METHODS

TLEMsafe is a European Project dedicated to generating semi-automated 3-D image-analyzing tools to simulate the musculoskeletal (M-S) system. The patient-specific parameters are fed into models with which the patient specific functional outcome can be predicted. Hence, we can analyze the functional effect e.g. due to placement of prosthetic components in a patient. Surgeons can virtually operate on the patient-specific model after which the model predicts the functional effects. Once the optimal plan is selected, this is fed into a computer navigation system (see figure 1).


Matthias Verstraete Catherine Van Der Straeten Gert-Jan Opsomer Bram De Lepeleere Jan Victor

An accurate evaluation of the mechanical properties of human tissue is key to understanding and successfully simulating (parts of) human joints. Due to the rapid post-mortem decay, however, the cadavers are usually frozen or embalmed. The main aim of this paper is to quantitatively compare the impact of both techniques on the biomechanical properties. To that extent, the Achilles tendons of seven cadavers have been tested. For each cadaver, one of the Achilles tendons was tested after being frozen for at maximum two weeks, whilst the other tendon was tested following a Thiel embalming process.

All specimens were gripped in custom made clamps and subjected to uniaxial tensile loading. The specimens were scanned using a micro-CT to determine their cross-sectional area, which allowed transferring the applied forces to stresses. During the tensile tests, the specimens’ elongation was measured both using the digital image correlation (DIC) technique and using linear variable displacement transducers (LVDT's) mounted across the grips. The former allowed to assess the severity of slip in the grips. As is well described in literature, the obtained stress-strain relationship is not linear (Figure 1). Accordingly, the following bilinear relationship was fitted through the data points using a least squares fit:

s = E0 e     e <= ê

s = E0 ê + E (e - ê)     e > ê

As a result, the stress-strain response is sub-divided in two regions: a toe-region (e <= ê) with a low slope and stiffness (E0) and a linear elastic region (e > ê) with a higher stiffness (E). Both stiffness values were subsequently compared between the fresh frozen and Thiel embalmed group. Given the non-normal distribution of the test data, the non-parametric Wilcoxon signed rank test was used to assess the statistical significance of the obtained results.

No statistically significant difference was observed between the stiffness of the toe-region (e <= ê) obtained from Thiel embalmed and fresh frozen specimens (p-value = 0.249). In the contrary, the stiffness of linear elastic region (e > ê) was significantly different between both groups (p-value = 0.046 – see Figure 2). An average, the Thiel embalmed specimens displayed a 36% higher stiffness compared to the fresh frozen specimens. The latter contrasts the findings of other studies reported in literature, which report a decrease of the stiffness following Thiel embalming. To the authors’ opinion, this discrepancy could either be attributed to a difference in testing protocol (embalming time, donor factors, …) or tissue perfusion kinetics (Achilles tendon is relatively massive).

In conclusion, this study has demonstrated that Thiel embalming significantly alters the biomechanical properties of tendons. Specimens that underwent Thiel embalming should therefore not be considered for determining input parameters for advanced numerical models.


Matthias Verstraete Catherine Van Der Straeten Jan Victor

To evaluate the impact of a knee prosthesis on the soft-tissue envelope or knee kinematics, cadaveric lower extremities are often mounted in a custom test rig, e.g. Oxford knee rig. Using such test rig, the knee is tested while performing a squatting motion. However, such motion is of limited daily-life relevance and clinical practices has shown that squatting commonly causes problems for knee patients. As a result, a new test rig was developed that allows a random, controlled movement of the ankle relative to the hip in the sagittal plane.

Mounting the specimen in the test rig, restricts five degrees of freedom (DOF) at the hip; only the rotation in the sagittal plane is not restrained (Figure 1). On the other hand, at the ankle, only two degrees of freedom are restrained, namely the movement in the sagittal plane. The ankle has thus three rotational degrees of freedom, all rotation axis intersect in a single point: the center of the ankle. In addition, the out-of-plane translational movement of the ankle remains free. This is achieved by means of a linear bearing. The other translational degrees of freedom, in the sagittal plane, are controlled by two actuators. As a result, the knee has five degrees of freedom left; flexion-extension is controlled. This represents typical closed chain applications, such as cycling.

In a first step, the knee kinematics have been evaluated under un-loaded conditions (no quadriceps or hamstring forces applied). To evaluate the knee kinematics, an infrared camera system (OptiTrack, NaturalPoint Inc, USA) is used. Therefore, three infrared markers are placed on the femur and tibia respectively. In addition, markers are placed on the test rig itself, to evaluate the accuracy of the applied motion. All markers are tracked using eight infrared cameras. At the ankle, a 2D circular motion with a radius of 100 mm was applied. Based on the 3D motion analysis, it was demonstrated that the control system has an accuracy of ± 0.5 mm.

The evaluation of the knee kinematics in accordance to Grood and Suntay (J. of Biomechanical Engineering, 1983), additionally requires the evaluation of the knee anatomy. To that extent, the cadaveric specimen has been visualized using a CT scan, with the infrared markers in place. From these CT images, a 3D reconstruction has been created (Mimics, Materialise, Belgium). Subsequently, custom software has been developed that combines the CT data with the motion analysis data (Matlab, The MathWorks Inc., USA). As a result, knee motion is visualized in 3D (Figure 2.a) and clinical relevant kinematic parameters can be derived (Figure 2.b).

In conclusion, the presented test rig and analysis framework is ready to evaluate more complex knee kinematics with reasonable accuracy and stability of the control loops. Future research will however primarily focus on the evaluation and validation of the impact of forces applied onto the specimen.


Matthias Verstraete Thomas Luyckx Karel De Roo Johan Bellemans Jan Victor

It is nowadays widely recognized that patient satisfaction following knee arthroplasty strongly depends on ligament balancing. To obtain this balancing, the occurring ligament strain is assumed to play a crucial role. To measure this strain, a method is described in this paper that allows full field 3D evaluation of the strains. The latter is preferred over traditional measurement techniques, e.g. displacement transducers or strain gauges, as human soft tissue is not expected to deform uniformly due to its highly inhomogeneous and anisotropic properties.

To facilitate full field strain measurements, the 3D digital image correlation (DIC) technique was adopted. This technique was previously validated by our research group on human tissue. First, a high contrast speckle pattern was applied on the sMCL. Therefore, the specimens are first coated with a small layer of methylene blue. Following, a random white speckle pattern is applied. During knee flexion, two cameras simultaneously take pictures of the deforming region at predefined flexion angles. Using dedicated software, the captured images are eventually combined and result in 3D full field strains and displacements.

Using this method, the strain distribution was studied in six cadaveric knees during flexion extension movement. Therefore, the femur was rigidly fixed in a custom test rig. The tibia was left unconstrained, allowing the six degrees of freedom in the knee. A load was applied to all major muscles in physiological directions of each muscle by attaching a series of calibrated weights (Farahmand et al., J Orthop Res., 1998;16(1)). The direction of the pulling cables was controlled using a digital inclinometer for each specimen. As a result, a statically balanced muscle loading of the knee was obtained.

From these cadaveric experiments, it is observed that on average the sMCL behaves isometrically between 0° and 90° of flexion. However, high regional differences in strain distribution are observed from the full field measurements. The proximal region of the sMCL experiences relatively high strains upon flexion. These strains are positive (tension) in the anterior part and negative (compression) in the posterior region. In contrast, the distal region remains approximately isometric upon knee flexion (see Figure 1).

It is accordingly concluded that the sMCL behaves isometric, though large regional differences are observed. The proximal region experiences higher strains. Furthermore, the DIC technique provided valuable insights in the deformation of the sMCL. This technique will therefore be applied to study the impact of knee arthroplasty in the near future.

Caption with figure 1: Full field strain distribution in the sMCL's longitudinal direction for specimen in 45° (a) and 90° (b) of knee flexion


Hiroshi Wada Hajime Mishima Hisashi Sugaya Tomofumi Nishino Masashi Yamazaki Koji Hyodo

Introduction

The initial stress distribution in the femur after total hip arthroplasty (THA) influences the remodeling of the bone and the clinical results. We conducted thermoelastic stress analysis to evaluate the surface stress distribution in femurs after THA in vitro and elucidated the changes in the stress distribution that were due to the stem design. Using this method, we can analyze the change in the sum of the principal stresses on the basis of the changes in temperature at the bone surface and visualize the change three-dimensionally.

Objectives

We compared the thermoelastic stress analysis results with the clinical results of specially shaped stems that have two flanges, one anterior and one posterior.


Keizo Wada Hiroshi Mikami Koichi Oba Norio Yamamoto Shunichi Toki Koichi Sairyo

Introduction

The aim of this study is to verify the intra-rater and inter-rater reliability of intra-operative kinematics by hand in TKA using a computer assisted image-free navigation system.

Material and Methods

Total knee arthroplasty (TKA) was performed on the knees of twelve (12) patients with knee navigation by one surgeon. Patients were divided into two groups: Group A included six knees that were operated on with assistant A (senior joint surgeon); and Group B included the other six knees that were operated on with assistant B (resident). For each knee, axial rotation was evaluated three times by the operator and the assistant using a navigation system at 30°, 60°, 90°, 120° passive flexions by hand. Intra-class correlation coefficients (ICC) were calculated for each evaluation to examine intra-rater and inter-rater reliability.


Bradford Waddell David Briski Mark S. Meyer J. Lockwood Ochsner George Chimento

Introduction

Periprosthetic joint infection (PJI) is a significant challenge to the orthopedic surgeon, patient, hospital, and insurance provider. As the number of total hip and knee replacements has increased, the number of revision procedures has also increased. Revisions for infection require a greater amount of hospital and surgeon resources than noninfectious revisions. Our study compares the financial information for all two-stage revision surgeries performed at our tertiary referral center for hip or knee PJI over the last four years, separating them into two groups: referral versus self-originating cases.

Methods

We performed a review of all patients who underwent two-stage revision hip or knee arthroplasty for infection between 2008 and 2013 at our facility. We collected detailed financial information for patients and separated them into referral versus self-originating cases, indicating whether index surgery was performed at an outside facility or at our facility, respectively. Only those patients who underwent full two-stage procedure at our facility were included.


William Kang Bradford Waddell Jennifer Bruggers Isabel Stephens George Chimento

Introduction

This study reports outcomes of primary and revision total hip arthroplasties of a recalled metal-on-metal (MOM) monoblock prosthesis performed by a single surgeon.

Methods

We performed a retrospective review of all patients who underwent both primary and revision total hip arthroplasties at our institution between 2006 and 2014. Only those patients who underwent primary recalled MOM monoblock prosthesis placement and/or revision of the recalled prosthesis were included. We evaluated revision group versus non-revision group for age, BMI, gender, existence of medical comorbidities, primary cup abduction and anteversion, primary combined angle, post-operative complications, cobalt and chromium ion levels, and Harris Hip Scores. Student t-test was used to compare groups.


David Walker Allison Kinney Aimee Struk B.J. Fregly Thomas Wright Scott Banks

Reverse total shoulder arthroplasty (RTSA) is increasingly used in the United States since approval by the FDA in 2003. RTSA relieves pain and restores mobility in arthritic rotator cuff deficient shoulders. Though many advantages of RTSA have been demonstrated, there still are a variety of complications (implant loosening, shoulder impingement, infection, frozen shoulder) making apparent much still is to be learned how RTSA modifies normal shoulder function. The goal of this study was to assess how RTSA affects deltoid muscle moment generating capacity post-surgery using a subject-specific computational model driven by in vivo kinematic data.

A subject-specific 12 degree-of-freedom (DOF) musculoskeletal model was used to analyze the shoulders of 27 subjects (14-RTSA, 12-Normal). The model was modified from the work of Holzbaur et al. to directly input 6 DOF humerus and scapula kinematics obtained using fluoroscopy. Model geometry was scaled according to each subject's skeletal dimensions. In vivo abduction kinematics for each subject were input to their subject-specific model and muscle moment arms for the anterior, lateral and posterior aspects of the deltoid were measured over the arc of motion.

Similar patterns of muscle moment arm changes were observed for normal and RTSA shoulders. The moment arm of the anterior deltoid was positive with the arm at the side and decreased monotonically, crossing zero (the point at which the muscle fibers pass across the joint center) between 50°–60° glenohumeral abduction (Figure 1a). The average moment arm of the lateral deltoid was constant and positive in normal shoulders, but showed a decreasing trend with abduction in RTSA shoulders (Figure 1b). The posterior deltoid moment arm was negative with the arm at the side, and increased monotonically to a positive value with increasing glenohumeral abduction (Figure 1c). Subject-specific moment arm values for RTSA shoulders were highly variable compared to normal shoulders. 2-way repeated measures ANOVA showed significant differences between RTSA and normal shoulders for all three aspects of the deltoid moment arm, where the moment arms in RTSA shoulders were smaller in magnitude.

Shoulder functional capacity is a product of the moment generating ability of the shoulder muscles which, in turn, are a function of the muscle moment arms and muscle forces. Placement of implant components during RTSA can directly affect the geometric relationship between the humerus and scapula and, therefore, the muscle moment arms in the RTSA shoulder. Our results show RTSA shoulders maintain the same muscle moment arm patterns as healthy shoulders, but they show much greater inter-subject variation and smaller moment arm magnitudes. These observations show directly how RTSA configuration and implant placement affect deltoid moment arms, and provide an objective basis for determining optimal implant configuration and surgical placement to maximize RTSA function in a patient-specific manner.


David Walker Allison Kinney Aimee Struk B.J. Fregly Thomas Wright Scott Banks

Reverse total shoulder arthroplasty (RTSA) is an increasingly common treatment for osteoarthritic shoulders with irreparable rotator cuff tears. Although very successful in alleviating pain and restoring some function there is little objective information relating geometric changes imposed by the reverse shoulder and the moment generating capacity of the shoulder muscles. Recent modeling studies of reverse shoulders have shown significant variation in deltoid muscle moment arms over varied joint centers for shoulders with RTSA. The goal of this study was to investigate the sensitivity of muscle moment arms as a function of varying the joint center in one representative RTSA subject. We hypothesized there may exist a more beneficial joint implant placement, measured by muscle moment arms, compared to the actual surgical implant placement.

A 12 degree of freedom, subject-specific model was used to represent the shoulder of a patient with RTSA for whom fluoroscopic measurements of scapular and humeral kinematics during abduction had been obtained. The computer model used these abduction kinematics and systematically varied joint center locations over 1521 different perturbations from the surgical placement to determine moment arms for the anterior, lateral and posterior aspects of the deltoid muscle. The joint center was varied from its surgical position ±4 mm in the anterior/posterior direction, 0–24 mm in the medial/lateral direction, and −10 mm to 14 mm in the superior/inferior direction.

The anterior deltoid moment arm varied up to 16mm with center of rotations variations, primarily in the medial/lateral and superior/inferior directions (Figure 2, Table 1(Figure 1)). Similarly, the lateral deltoid moment arm demonstrated variations up to 13 mm, primarily with joint center changes in the anterior/posterior and superior/inferior directions. The posterior deltoid moment arm varied up to 10mm, primarily in early abduction, and was most sensitive to changes of the joint center in demonstrated a sensitivity of 6 mm corresponding to variations in the superior/inferior directions (Figure 2).

The goal of this study was to assess the sensitivity of the deltoid muscle moment arms as a function of joint configuration for an existing RTSA subject. High variations were found for all three deltoid components. Variation over the entire abduction arc was greatest in the anterior and lateral deltoid, while the posterior deltoid moment arm was mostly sensitive to joint center changes early in the abduction arc. Moment arm changes of 10–16mm represent a significant amount of the total deltoid moment arm. This means there is an opportunity to dramatically change the deltoid moments arms through surgical placement of the joint center of rotation. Computational models of the shoulder may help surgeons optimize subject-specific placement of RTSA implants to provide the best possible muscle function, and assist implant designers to configure devices for the best overall performance.


David Walker Aimee Struk Thomas Wright Scott Banks

Reverse total shoulder arthroplasty (RTSA) has had rapidly increasingly utilization since its approval for U.S. use in 2004. RTSA accounted for 11% of extremity market procedure growth in 201. Although RTSA is widely used, there remain significant challenges in determining the location and configuration of implants to achieve optimal clinical and functional results. The goal of this study was to measure the 3D position of the shoulder joint center, relative to the center of the native glenoid face, in 16 subjects with RTSA of three different implant designs, and in 12 healthy young shoulders.

CT scans of 12 healthy and 16 pre-operative shoulders were segmented to create 3D models of the scapula and humerus. A standardized bone coordinate system was defined for each bone (Figure 1). For healthy shoulders, the location of the humeral head center was measured relative to the glenoid face center. For the RTSA shoulders, a two-step measurement was required. First, 3D models of the pre-operative bones were reconstructed and oriented in the same manner as for healthy shoulders. Second, 3D model-image registration was used to determine the post-operative implant positioning relative to the bones. The 3D position and orientation of the implants and bones were determined in a sequence of six fluoroscopic images of the arm during abduction, and the mean implant-to-bone relationships were used to determine the surgical positioning of the implants (Figure 2). The RTSA center of rotation was defined as the offset from the center of the implant glenosphere to the center of the native glenoid face.

The center of rotation in RTSA shoulders varied over a much greater range than the native shoulders (Table 1 (Figure 3)). Lateral offset of the joint center in RTSA shoulders was at least 6 mm smaller than the smallest joint center offset in the healthy shoulders. The center of rotation in RTSA shoulders was significantly more inferior than in healthy shoulders. The range of anterior/posterior placement of the rotation center for RTSA shoulders was bounded by the range for normal shoulders.

How to best position RTSA implants for optimal patient outcomes remains a topic of great debate and research interest. We found that the 3D joint center position can vary over a supraphysiologic range in shoulders with RTSA, and that this variation is primarily in the coronal plane. By relating these geometric variations to muscle, shoulder and clinical function, we hope to establish methods and strategies for predictably obtaining the best clinical and functional outcomes for RTSA patients on a per-subject basis.


David Walker Allison Kinney B.J. Fregly Thomas Wright Scott Banks

Current modeling techniques have been used to model the Reverse Total Shoulder Arthroplasty (RTSA) to account for the geometric changes implemented after RTSA. Though these models have provided insight into the effects of geometric changes from RTSA these is still a limitation of understanding muscle function after RTSA on a patient-specific basis. The goal of this study sought to overcome this limitation by developing an approach to calibrate patient-specific muscle strength for an RTSA subject.

The approach was performed for both isometric 0° abduction and dynamic abduction. A 12 degree of freedom (DOF) model developed in our previous work was used in conjunction with our clinical data to create a set of patient-specific data (3 dimensional kinematics, muscle activations, muscle moment arms, joint moments, muscle length, muscle velocity, tendon slack length, optimal fiber length, peak isometric force)) that was used in a novel optimization scheme to estimate muscle parameters that correspond to the patient's muscle strength[4]. The optimization varied to minimize the difference between measured(“in vivo”) and predicted joint moments and measured (“in vivo”) and predicted muscle activations. The predicted joint moments were constructed as a summation of muscle moments. The nested optimization was implemented within matlab (Mathworks). The optimization yields a set of muscle parameters that correspond to the subject's muscle strength. The abduction activity was optimized.

The maximum activation for the muscles within the model ranged between .03–2.4 (Figure 1). The maximum joint moment produced was 11 newton-meters. The joint moments were reproduced to an value of 1. Muscle parameters were calculated for both isometric and dynamic abduction (Figure 2). The muscle parameters produced provided a feasible solution to reproduce the joint moments seen “in vivo” (Figure 3).

Current modeling techniques of the upper extremity focus primarily on geometry. In efforts to create patient-specific models we have developed a framework to predict subject-specific strength characteristics. In order to fully understand muscle function we need muscle parameters that correspond to the subject's strength. This effort in conjunction with patient-specific models that incorporate the patient's joint configurations, kinematics and bone anatomy hopes to provide a framework to gain insight into muscle tensioning effects after RTSA. With this framework improvements can be made to the surgical implementation and design of RTSA to improve surgical outcomes.


Peter Walker Patrick Meere Christopher Bell

There are many different approaches to achieving balancing in total knee surgery. The most frequently used method is to obtain correctly aligned bone cuts, and then carry out necessary soft tissue releases to achieve equal flexion and extension gaps. In some techniques, the bone cuts themselves are determined by the prevailing soft tissue status or the kinematics during flexion-extension. Navigation can provide quantitative data during these processes but so far, navigation is used in only in a minority of cases. However in recent years, new technologies have been introduced with lower cost and implementation time, allowing for more widespread use. Early studies have indicated that more reproducible balancing can be obtained, and that balancing has a positive effect on clinical outcomes. However the ability to measure balancing quantitatively during surgery, has raised the questions of the most systematic method for implementation during surgery, and the relative influence of various correcting factors. Further, the ideal balancing parameters with respect to varus-valgus ratios and the magnitudes during a full flexion range, have yet to be defined. Even if normative data is the target, there is scant data on this topic.

In our own laboratory, we carried out experiments on knee specimens where the various surgical variables were systematically investigated for their effect on varus-valgus balancing. Different tests were developed including the ‘Heel Push Test’ where lateral and medial contact forces were plotted as a function of flexion. Imbalances were achieved with either bone cut adjustments or soft tissue releases. The major finding was that adjustments of only 2 mms or 2 degrees could correct most imbalances. This was considered to be due to two effects; the pretension in the ligaments bringing the structure to the stiff part of the load-elongation curve, and the high values of the stiffness itself. Medial-lateral equality was the goal in this work, but recognizing that this may not be the situation in the normal knee. To answer this question, we developed a method for measuring the varus-valgus balancing in normal subjects, using a ‘Smart Knee Fixture’ with embedded stretch sensors. We validated this device using cadaveric specimens, and normal volunteers using fluoroscopy and electromyography. We are now applying the method in an IRB study to both normals and post-operative knee replacement cases. For the latter, the relation between operative data, and post-operative balancing will be studied, as well as the relation of balancing to functional outcomes.

This overall subject of balancing at surgery, and the post-operative effects, is open to extensive experimental research, and is predicted to result in improved outcomes.


Peter Walker Michael Lowry Sally Arno Ilya Borukhov Christopher Bell

Total Knee Arthroplasty (TKA), has now become a reliable, successful, and widely used treatment for osteoarthritis. Numerous reports indicate that for the majority of patients, the TKA lasts a lifetime with pain relief and the ability to perform most everyday activities. However there are a number of ways in which the procedure can be further improved, the focus here being on function. One of the problems in evaluating function is that it depends upon the inherent ability, motivation, and expectation of the patients. There are several well-used questionnaire systems which capture functional ability objectively. In the effort to simplify evaluation, a ‘forgotten knee’ evaluation has been introduced, the concept being that ‘the ideal TKA design’ would feel and function like a normal knee. Such a measure would include factors such as surgical technique, alignment, and rehabilitation, as well as the TKA design itself. Another approach to evaluation is to measure biomechanical parameters, such as in gait analysis and fluoroscopy, which evaluate kinematic or kinematic parameters, using normal controls for comparison. Nevertheless, such evaluations still include factors other than the TKA design itself, and do not apply to new designs.

The approach taken here for the evaluation of a new TKA design independent of other factors, is to measure the neutral path of motion and the laxity boundaries of the loaded knee on the application of shear and torque over a full range of flexion. The benchmark is the same kinematic data from the normal intact knee. The rationale has some analogy to the ‘forgotten knee’ in that if the laxity response of a design of TKA is the same as that of the anatomic knee itself, the behavior of that implanted knee in any functional condition will be indistinguishable from that of the anatomic knee itself. Such a testing concept has some similarities to the constraint test described in the ASTM standard. In this paper, a novel design algorithm is proposed for creating different design concepts. First, a general morphological form is formulated for each design concept, a Cam-Post PS, a Saddle-Ramp, and a Converging Condyle, all with overall anatomic-like surfaces. Each femoral component is then designed, which is then moved through the normal neutral path and laxity paths, which creates the tibial surface. The concepts are evaluated using a Desktop Knee Machine configured to move the knee dynamically through full flexion while applying combinations of compression, shear and torque; kinematic data being captured optically and plotted using custom software. The normal benchmark was obtained from 10 normal knee specimens, which showed the restraint of the medial femoral condyle to anterior displacement and the overall rollback and laxity laterally. Compared with standard CR and PS designs, the Guided Motion designs were seen to more closely resemble normal. It is proposed that this approach can result in designs which will more likely reproduce a ‘forgotten knee’ and achieve the optimal function for a given patient.


William Walsh Nicky Bertollo Ali Hamze Chris Christou Bo Gao Laurent Angibaud

Introduction

Biological fixation through bone ingrowth and ongrowth to implants can be achieved with a variety of surface treatments and technologies. This study evaluated the effect of two different three dimensional surface coatings for CoCr where porosity was controlled through the use of different geometry of CoCr beads in the sintering process.

Methods

Test specimens in Group A were coated with conventional spherical porous-bead technology. The porous coating technology used on Group B was a variation of the conventional porous-bead technology. Instead of spherical beads, cobalt-chromium particles in irregular shapes were sieved for a particular size range, and were sintered onto the specimen substrate using similar process as Group A. The geometry and the size variation of the particles resulted in a unique 3D porous structure with widely interconnected pores.

Three implants were placed bicortically in the tibia. Two implants were placed in the cancellous bone of the medial distal femur and proximal tibia bilaterally with 4 implantation conditions (2 mm gap, 1 mm gap line-to-line, and press fit). Animals were euthanized at 4 or 12 weeks for standard mechanical, histological and histomorphometric endpoints.


Selin Munir Andrew Stephens Paul Thornton-Bott William Walter

Purpose

The aim of this study is to describe the influence of sitting and standing posture on sagittal pelvic inclination in preoperative total hip replacement patients to assist with correct acetabular component positioning.

Methods

Lateral radiographs of the pelvis and lumbar spine in sitting and standing of preoperative hip arthroplasty patients with primary hip osteoarthritis were extracted. Pelvic tilt was measured using the vertical inclination of a line from the ASIS to pubic tubercle. Sacral inclination was measured as the angle between the anterior surface of the sacrum and a horizontal reference. Figure one is a representation of the pelvic tilt angle and sacrel inclination angle taken during standing. The Cobb angle of the lumbar spine was recorded represented for a sitting patient in figure 2. Hip flexion was recorded (figure 2).


Selin Munir Dennis Molloy Tim Hasted Christopher M Jack Andrew Shimmin William Walter

Sagittal stability of the knee is believed to be of significant importance following total knee arthroplasty. We examine four different knee designs at a minimum of twenty-four months postoperatively. Sagittal stability was measured at four degrees of flexion: 0°; 30°; 60°; and 90°, to examine the effect of design on mid-flexion stability.

The knee designs included were: the rotating platform LCS design (DePuy); the cruciate sparing Triathlon system (Stryker); SAIPH system (Matortho, UK); and the medial rotating knee design, MRK (Matortho, UK).

Following ethical approval, 64 cases were enrolled into the study, 22 male and 42 female. Inclusion criteria included: a minimum of 18 months from surgery; ability to flex beyond 90 degrees; and have no postoperative complications. 18 LCS, 18 MRK, 14 SAIPH and 14 Triathlon knee designs were analysed. Sagittal stability was measured using the KT1000 device. Active range of movement was measured using a hand held goniometer and recorded as was Oxford knee score, WOMAC knee score, SF12 and Kujala patellofemoral knee score.

Mean follow-up was 33.7 months postoperative, with a mean age of 72 years. Mean weight was 82.7kgs and height 164cms. There was no significant difference in preoperative demographics between the groups. Mean active post-operative range of motion of the knee was from 2–113° with no significant difference between groups.

Sagittal stability was similar in all four groups in full extension; however the MRK and SAIPH designs showed improved stability in the mid-range of flexion (30–90°). Patient satisfaction also showed a similar trend with MRK achieving better patient reported functional outcomes and satisfaction than that of the SAIPH, LCS and Triathlon systems.

All four knee designs demonstrated good post-operative range of movement with comparative improvement of patient scores to other reported studies. The MRK and SAIPH knee design showed an improved mid-flexion sagittal stability with better patient reported satisfaction and functional scores.


Paul Thornton-Bott Stephen Tai William Walter William Walter Bernard Zicat

Introduction and Aims

The 21st Century has seen ceramic bearings become an increasingly popular choice in total hip arthroplasty due to their high wear resistance and inert wear debris without osteolysis promising a long term bearing solution. Early ceramic bearings were hindered by fracture but improved manufacturing processes and materials subsequently produced stronger ceramics. These third generation ceramics showed greatly reduced fracture rates but there is limited evidence in the literature reporting their long term survival and wear characteristics. The purpose of this study was to determine osteolysis and survival rates of Alumina ceramic bearings in cementless total hip arthroplasties with a minimum follow-up of 15 years.

Methods

We analyzed a series of 301 third-generation alumina-on-alumina cementless primary total hip replacements in 283 patients. The average age of the patients at the time of the arthroplasty was fifty-eight years, 51% were in women and 54% were right sided. All procedures were performed using the same surgical technique and the same implant at a single centre. Patients were followed up at six weeks, one, two, five, ten and 15 years. At 15 years postoperatively 46 patients (17%) had died of unrelated causes and 31 (10.2%) were lost to follow-up. Patients were assessed clinically and radiographically. Retrieved bearings were analyzed for wear.


Paul Thornton-Bott Stephen Tai William Walter Bernard Zicat

Background

Total Hip Arthroplasty (THA) using the Direct Anterior Approach (DAA) is a muscle sparing approach which promotes early mobilisation of patients. It is a technically challenging approach shown to have a high rate of complications, especially during the learning curve. Here we present the results of 157 cases of THA via a DAA on a standard theatre table, with a minimum of 6 months follow-up.

Materials & Methods

The authors conducted a prospective study on a group of 149 consecutive patients undergoing 157 cementless primary THAs for coxarthrosis, 8 bilateral. The same surgical technique was used in all patients, performed by the senior author WLW at a single centre. The average age of the patients at time of surgery was 69 years, 78% were female and 57% were right sided. All implants were uncemented, with bearings being ceramic on ceramic or Ceramic on highly cross-linked polyethylene. Patients were assessed clinically and radiographically pre- and post-operatively at 6 weeks, 6 months, 1 and 2 years. Intra-operatively, navigation was used to guide cup position and assess offset and leg length.


Wen-Kai Chou Andy Chien Jaw-Lin Wang

PEEK rods construct has been proposed to allow better load sharing among spinal components when compared to the more traditional Titanium rods constructs. However, such proposal has largely derived from single-load in-vitro testing and the biomechanical differences between the two constructs when subjected to fatigue loading remain unknown. Current study comparatively analyzed the in-vitro biomechanical performance of PEEK and Titanium rod constructs as spinal implants through a 5 hour fatigue loading test. The disc height and intradiscal pressure of the instrumented and adjacent levels pre- and post-loading were recorded for analysis. The stress levels on the rods and bone stress near the screw-bone interface were also collected to investigate the likely failure rates of the two constructs. The results showed that the Titanium rods construct demonstrated a minimum amount of loss of disc height and intradiscal pressure at the instrumented level, however, a significant loss of the disc height and intradiscal pressure at adjacent levels compared to the intact spine were identified. In contrast, the disc height and intradiscal pressure of the PEEK rods were found to be comparable to those of the intact spine for all levels. The PEEK rods group also showed significantly less bone stress near the screw-bone interface compared to the Titanium rods group. Current study has demonstrated the potential benefits of the PEEK rods construct in reducing the risks of adjacent segment disease and implant failure rates when compared to the more traditional Titanium rods construct.


Toshiro Warita Takanori Kitagawa Hiroki Kobayashi Takahisa Sato Kenji Takagishi

Objective

Recently, the short stem, taken on preservation of the femoral bone, is available on total hip arthroplasty and on femoral head prosthetic replacement. The handling of the short stem is easier than that of standard stem on implantation of femur. However, it would be difficult to make the direction of stem axis straight in femoral marrow cavity. Actually we experienced that the lateral cortical bone of the proximal femur was ground unevenly on rasping for implantation of the short stem. The aim of this study was to identify the efficacy of dulled rasp on implanting the short stem.

Subjects and Methods

We examined 42 hips of 39 patients who underwent the primary total hip arthroplasties with short stems in our institution from August 2011 to April 2014. Primary diseases were 28 osteoarthritides, 6 idiopathic osteonecrosises of the femoral heads and 5 others. We categorized N group as using standard rasp with sharpened blades and M group as using modified rasp with dulled blades named ‘Mild Rasp’, and analyzed with the statistical methods.


Mohammad Waseem Kaira Pearson Rui Zhou

Whilst the use of reverse total shoulder arthroplasty is becoming more common for the treatment of rotator cuff arthropathy, there is still relatively little evidence with regards to its use in complex fractures of the proximal humerus in the elderly. It is increasingly felt to be of use in those patients in whom either internal fixation is not possible due to fracture configuration or bone quality, or in whom there is a rotator cuff deficiency.

We report the outcomes of 14 patients with complex 3- or 4-part humeral fractures or delayed presentation of dislocation treated with reverse TSR. Patients were treated within a two year period from January 2011 to December 2013. The average age at time of operation was 75 (50–91 years) with a mean follow-up of 7 months (2–13 months). One patient moved out of area and one lost to follow-up two months following procedure.

Reverse TSR was considered a salvage procedure for patients with comminuted proximal humeral fractures or those who presented with irreducible non-acute dislocations. At time of last follow-up all 14 patients were satisfied with the results of their operation and functionally independent with activities of daily living. Range of movement post-operatively was good with mean active forward extension 97° (70–150°) and abduction 101° (80–170°). 43% of patients were pain-free, whilst the remainder only required the use of occasional analgesia. No major post-operative complications were reported.

Patients who underwent reverse TSR for dislocation fared better than for those with proximal humeral fractures. The mean active forward extension was 107.5° (90–150°) and abduction 112.5° (90–170°) in the dislocation group (n=5) compared with those who had a fracture in which the forward extension was 91.4° (70–120°) and abduction 95° (80–120°).

The results of these patients demonstrate that reverse TSR should be considered in patients with complex proximal humeral fractures or delayed presentation of fractures. It seems to provide consistently excellent pain-relief for patients, with patients either reporting being pain-free or requiring only occasional analgesia. In addition, all patients treated were functionally independent following operation. Range of movement, particularly for those with dislocation, appear good. Further follow-up is required to ensure sustained results but early studies are encouraging.


Kunihiko Watamori Masami Ishimaru Yoshio Onishi Kazunori Hino Hiromasa Miura

Introduction

Previous anthropometric studies have reported gender differences in distal femoral morphology. After total knee arthroplasty, females have a higher prevalence of medial or lateral femoral component overhang, which could be responsible for postoperative knee pain and decreased range of motion. Consequently, gender-specific knee prostheses were designed to accommodate female morphology. However, to date, very few studies have investigated the knee morphology of Japanese adults and possible gender differences. The purpose of this study was to examine the distal femoral morphology of Japanese patients, to characterize anatomical differences between men and women, and to evaluate the need to create gender-specific knee prostheses.

Material and Methods

We evaluated 107 knees in 17 male and 90 female Japanese patients for total knee arthroplasty (TKA)[fig.1]. The medial-lateral (ML) and anteroposterior (AP) dimensions of the knees at different levels evaluated intraoperative measurement, and ML/AP aspect ratios were calculated.


Toshifumi Watanabe Takeshi Muneta Ichiro Sekiya Hideyuki Koga Masafumi Horie Tomomasa Nakamura Koji Otabe Scott Banks

INTRODUCTION

Total knee arthroplasty (TKA) is one of the most successful and beneficial treatments for osteoarthritic knees. We have developed posterior-stabilized (PS) total knee prosthesis for Asian patients, especially Japanese patients, and have used it since November, 2010. The component was designed based on the CT images of osteoarthritic knees, aiming to achieve deep flexion and stability. The purpose of this study was to analyze in- vivo kinematics of this new prosthesis.

METHODS

We analyzed a total of 28 knees implanted with PS TKAs: Fourteen knees with the new PS prosthesis (group A), and the other fourteen knees with a popular PS prosthesis as a control group (group B). Preoperative data of both groups were not significantly difference. Flat-panel radiographic knee images were recorded during five static knee postures including full extension standing, lunge at 90° and maximum flexion, and kneeling at 90° and maximum flexion. The three-dimensional position and orientation of the implant components were determined using model-based shape matching techniques. The results of this shape-matching process have standard errors of approximately 0.5° to 1.0° for rotations and 0.5 to 1.0 mm for translations in the sagittal plane. Unpaired t-tests were used for statistical analysis and probability values less than 0.05 were considered significant.


Kenichi Watanabe Masayuki Kyomoto Shihori Yamane Kazuhiko Ishihara Yoshio Takatori Sakae Tanaka Toru Moro

The modification of bearing surfaces with poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) is known to increase the hydration of the surfaces and decrease the wear of the substrates. PMPC grafting to acetabular liner of total hip arthroplasty showed a drastic reduction of cross-linked polyethylene (CLPE) wear in a long-term hip simulator test and achieved a good short-term clinical result. To apply this technique to other joint prostheses, the wear resistance under various conditions needs to be evaluated because every joint has a different wear mode. ASTM F732 gives a method that disk shaped polymer specimen is loaded with hemispherical pin using pin-on-disk tester, which is suitable for hydrated polymer because the lubricant is supplied every loading cycle on the surface. The purpose of this study is to evaluate the performance of PMPC-grafted hydrated CLPE under multidirectional wear condition in anticipation of applying PMPC to various prostheses.

The CLPE disks of 3 or 6-mm in thickness were machined from a bar stock. The PMPC was grafted onto the CLPE surfaces using a photoinduced polymerization of MPC in aqueous medium. All disks were irradiated with a total amount of 75-kGy gamma-ray. The wear resistance of the CLPE and PMPC-grafted CLPE disks against Co-Cr-Mo alloy pin was evaluated using Ortho-POD pin-on-disk tester. The disks were fixed to the tester with a Ti-6Al-4V alloy plate that has screw hole in the center. The test conditions were a static load of 213 N, sliding shape of 5 mm × 10 mm rectangular, frequency of 1 Hz and maximum cycles of 1.0 × 106 [Fig. 1]. Gravimetric wear was determined by weighing the disks and soak controls were used to compensate for the fluid absorption. After the wear test, volumetric changes of sliding and backside surfaces of disks were evaluated using a noncontact optical three-dimensional profiler.

The PMPC-grafted surface showed decrease in the gravimetric wear drastically [Fig. 2]. The thickness of CLPE had no substantial effect on the wear resistance. Three-dimensional profile measurements of sliding surfaces detected a substantial volumetric penetration; the corner of sliding track were deeper than the straight-line portion. Backside extrusion was observed in all disks. The thickness of CLPE affected both volumetric penetration and backside extrusion for both untreated and PMPC-grafted CLPE. The PMPC grafting had no discernible effect on volumetric changes [Fig. 3].

Results of this study revealed: (1) the PMPC-grafted surface decreases wear of CLPE, however, the thickness of disk has no effect, in contrast, (2) thinner thickness of CLPE increases the volumetric changes including penetration in sliding surface and extrusion in back surface but the PMPC-grafted surface has no effect. Gravimetric wear did not correlate with the volumetric penetration in sliding surface because the volumetric penetration might be caused by not only the wear but also the creep deformation. In conclusion, hydrated bearing surface and thickness of bearing substrate are essential for the wear and fatigue resistance properties for an increasing longevity of artificial joint. In addition, PMPC grafting is a promising technique for increasing the longevity of various joint prostheses.


Hitoshi Watanabe Masaaki Sakamoto

There have been numerous reports regarding “pseudotumor” associated with hip arthroplasty. We present two reports in which main etiology in the pseudotumor formation was titanium (Ti), but not cobalt-chromium (Co-Cr). We should keep in mind that Ti analysis is essential in some cases.

(Case 1) A 68-year-old male presented to our institution because of right hip pain and lower extremity swelling four years after a bipolar hemiarthroplasty. MRI predicted a cystic pseudotumor. However, revision surgical findings showed no apparent cause of ARMD previously described in the literatures. Postoperative analysis showed that the metal debris mainly originated from the Ti alloy itself. (Case reports in Orthopedics, vol.2014, Article ID 209461, 4 pages)

(Case 2) A 77-year-old female presented to our institution because of right hip pain and swelling six years after a total hip arthroplasty using a cable trochanteric reattchment. Plain radiographs demonstrated evidences of severe osteolysis and multiple fragments of the broken cable. However, MRI predicted a psudotumor(See Figure 1). Postoperative analysis clarified that main etiology in the pseudotumor formation was the stem mede of Ti, but not the cable made of Co-Cr.


Nobuyuki Watanabe Hisaki Aiba Gakuji Sagara Takaya Yamagami Yasuhiro Nishimori Yuya Waseda Yusuke Oguri Hiromi Onogi Hironari Sakurai Takanobu Otsuka

Purpose

According to Bipolar Hemiarthroplasty of the Hip (BHA), several reports indicated earlier acquisition of walking ability in direct anterior approach (DAA) than posterior approach (PA), but there is still few randomized studies comparing accuracy of stem insertion in DAA and PA. Therefore, we performed a prospective study, focusing positioning of implant.

Patient and Methods

We chose 29 patients for this study, diagnosed as femoral neck fracture (Garden grade III or IV) from April 2012 to April 2013, excluding obesity patients (body mass index upper than 30kg/m2), muscular patients, osteoporotic patients (Sigh grade I or II), and tumor bearing patients. Patients were enrolled in a prospective, non-blinded study and were randomly assigned by envelope method to receive either DAA or PA. Taperloc BHA system (Zimmer) was adapted for all cases. Patient condition, operation condition and radiographic findings were investigated. On CT imaging, Canal fill was calculated Stem fill was studied at lower point of lesser trochanter that was considered to be load center. Static analysis was carried out using SPSS ver21 (IBMc). Continuous variables between the two groups were compared using a no matched bilateral Student's t-test. For nominal variables we used χ2test. P value <0.05 was considered to be significant. (Table1)


Kenichi Watanabe Masayuki Kyomoto Shihori Yamane Kazuhiko Ishihara Yoshio Takatori Sakae Tanaka Toru Moro

The main objective of joint arthroplasty is to improve activities of daily living of the patient. However, normal daily activities may lead to separation of articular surfaces of an artificial joint, possibly as a result of a combined impact and sliding motion. Therefore, the properties of articular surfaces define the durability of implant materials. Modification of bearing surfaces with poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) increases the hydration of the surfaces and decreases the wear of the substrates. Hence, a PMPC layer can potentially cushion the impact and improve the resistance of cross-linked polyethylene (CLPE). This study aimed to explore the fatigue and wear resistance of PMPC-grafted hydrated CLPE under impact-to-wear conditions using a pin-on-disk tester.

The surfaces of a CLPE disk (3- or 6-mm thick) were modified with PMPC by photoinduced polymerization and were sterilized using gamma rays. The wear resistance of PMPC-grafted CLPE disks against a Co-Cr-Mo alloy pin was evaluated and compared to that of untreated disks. The disks were fixed to the tester with a metal plate (Ti-6Al-4V alloy) that had a central hole. The test was performed for 2 × 106 cycles of repetitive impact and unidirectional sliding with the maximum load of 150 N, sliding distance of 10 mm, and frequency of 1 Hz [Fig. 1]. Gravimetric wear was determined by weighing the disks, and soak controls were used to compensate for fluid absorption. Volumetric changes in the surfaces of the disks were evaluated using a three-dimensional non-contact optical profiler.

The average gravimetric wear (mg) after 2 × 106 cycles was 0.000/0.120 for CLPE (3/6 mm) and −0.073/–0.137 for PMPC-CLPE (3/6 mm). The weight gain of the PMPC-CLPE disks was due to their greater fluid absorption compared to that of the soak controls under the impact-to-wear conditions, as judged from the fact that during the load-soak in the lubricant this gain was observed for all the disks irrespectively of PMPC grafting. PMPC-grafting decreased the gravimetric wear of CLPE (p < 0.01) in the 6-mm group, whereas the thickness of the CLPE disks had no substantial effect on the wear resistance [Fig. 2]. In all cases, three-dimensional measurements detected a remarkable volumetric penetration in the impact-sliding surfaces and an extrusion of CLPE from the backside surfaces into the hole in the metal plate. Both the volumetric penetration and backside extrusion were smaller in the 6-mm group. The PMPC grafting had no discernible effect on these volumetric changes [Fig. 3]. Even after 2 × 106 cycles of impact loads, mechanical fracture or delamination of the impact-sliding or backside surfaces were hardly observed in all the groups.

The results of this study revealed that: (1) PMPC-grafting of CLPE surfaces decreased the gravimetric wear irrespectively of the disk thickness; and (2) thinner CLPE increased the risk of volumetric changes, including penetration in the impact-sliding surface and extrusion of the backside surface. In conclusion, PMPC grafting can potentially improve the wear resistance of the bearing surface of biomaterials even under impact-to-wear conditions, increasing the longevity of artificial joints.


Satoshi Watanabe Taku Sato Osamu Tanifuji Hiroshi Yamagiwa Go Omori Yoshio Koga

Introduction

Computed tomography (CT) based preoperative planning provides useful information for severe TKA and revision TKA cases, such as the amount of augmentation, length of stem extension and component alignment, to achieve correct alignment and joint line. In this study, we evaluated TKA alignment performed with CT preoperative planning.

Materials and Methods

7 primary TKAs for severe deformity and 3 revision TKAs were included. CT preoperative planning was performed with JIGEN (LEXI, Japan). Constrained condylar prosthesis (LCCK, Zimmer) were used in all case. For femoral component, axial alignment was decided by controlled IM rod insertion to femoral canal. Rotational alignment was decided according to anterior cortex that usually was not compromised. For tibial component, axial alignment was set to perpendicular to tibial mechanical axis. Coverage and joint line level were carefully decided. The amount of bone resection of bilateral distal and posterior femoral condyle and proximal tibia was measured, respectively. Stem extension length and offset were selected according to components position and canal filling. Amount of augmentation was also estimated bilateral distal and posterior femoral condyle, respectively. Postoperative component alignment was evaluated three-dimensionally with Knee-CAS (LEXI, Japan).


Paul Stirling Radwane Faroug Megan Whittaker Tony Freemont

Objectives

The efficacy of Gram-stain microscopy for diagnosis of septic arthritis is fundamentally limited by an inherent false-negative rate of 25–50%. The aim of this study was to calculate the sensitivity of Gram-stain microscopy of synovial fluid collected in heparinised containers and to investigate if this collection method improves diagnostic value.

Methods

12-year retrospective study of patients undergoing synovial fluid analysis between 1998 and 2010. Gram-stain result was correlated with culture result and clinical diagnosis. The formula sensitivity = number of true positives/(number of true positives + number of false negatives) was used for analysis.


Erik Woodard John Williams William Mihalko

Introduction

When performing total knee arthroplasty (TKA), surgeons often utilize a posterior-stabilized (PS) design which compensates for the loss of the posterior cruciate ligament (PCL). These designs attempt to replicate normal knee kinematics and loading using a cam and post to provide posterior restraint of the tibia during flexion. However, these designs may not be able to compensate for the increase in flexion space or the inherent loss of coronal stability after PCL release compared to a cruciate retaining (CR) design. This study aimed to compare stability of PS and CR TKA designs by assessing laxity in three planes.

Methods

The specimens utilized in this study were lower extremities from fresh cadavers of donors who had previously undergone a total knee replacement (Medical Education and Research Institute (Memphis, TN) and Restore Life USA (Johnson City, TN)). IRB approval was obtained prior to performing the study. Twenty-three knee specimens (8 left, 15 right) were retrieved and all skin, subcutaneous tissue and muscle was removed. The femur and tibia were cut transversely 180 mm superior and inferior to the knee joint line, respectively, and specimens were mounted in a custom knee testing machine. Specimens were tested with the knee joint at full extension and at 30, 60, and 90 degrees of flexion. Laxity was assessed at 1.5 Nm of internal and external torque and 10 Nm varus and valgus torque, as well as a 35 N anterior and posterior force. Laxity was expressed as degrees of tibial displacement in the coronal plane under a varus/valgus torque and degrees of displacement in the transverse plane under an internal/external torque, as well as mm of anterior or posterior displacement. TKA components were retrieved to determine PS or CR design and grouped accordingly.


Brooke Sanford John Williams Kyle Huffman Audrey Zucker-Levin William Mihalko

Introduction

The sit-to-stand (STS) movement is a physically demanding activity of daily living and is performed more than 50 times per day in healthy adults. Several studies have shown that the normal ‘screw-home’ mechanism is altered after total knee arthroplasty (TKA). However, these studies have been criticized due to their limitations of the movement being non-weight-bearing or atypical daily activity (lunge maneuver). We analyzed TKA subjects during a STS activity to determine if the internal-external rotation of their TKA knees differed from the knees of control subjects.

Materials and Methods

Six TKA subjects (3 M, 3 F) participated following institutional review board approval and informed consent. One subject had bilateral knee replacement. Surgery was performed by the same surgeon using the same type of implant (6 posterior-stabilized, 1 cruciate-retaining). The control group included eight healthy subjects (6 M, 2 F).

Retro-reflective markers were placed over bony landmarks of the torso, pelvis, and lower extremities, and arrays of four markers were attached to the thighs and shanks using elastic wrap. A digitizing pointer was used to create virtual markers at the anterior superior iliac spines. A nine camera video-based opto-electronic system (Qualisys) was used for 3D motion capture. Subjects were barefoot and seated on a 46 cm armless bench with one foot on each force plate (AMTI). Subjects rose from their seated position, paused, and returned to the seated position at a self-selected pace repeatedly for 30 seconds. Subjects did not use their arms to push off the bench. Only the STS portion of the task was analyzed. The start of the STS cycle was defined when the C7 marker began to move forward in the sagittal plane and ended at the point of maximum knee extension. Only the right leg of the control subjects was used for analysis.


Brooke Sanford John Williams Audrey Zucker-Levin William Mihalko

Introduction

In a previous study of subjects with no history of lower extremity injury or disease we found a linear relationship between body weight and peak hip, knee, and ankle joint forces during the stance phase of gait. To investigate the effect of total knee arthroplasty (TKA) on forces in the operated joints as well as the other joints of the lower extremities, we tested TKA subjects during gait and performed inverse dynamics analyses of the results.

Materials and Methods

TKA subjects (3 M, 1 F; 58 ± 5 years; body mass index range (BMI): 26–36 kg/m2) participated in this investigation following institutional review board approval and informed consent. One subject had bilateral knee replacement. Each patient received the same implant design (4 PS, 1 CR). Data from previously tested control subjects (8 M, 4 F; 26 ± 4 years; BMI: 20–36 kg/m2) were used for comparison.

Retro-reflective markers were placed over bony landmarks of each subject. A nine-camera video-based opto-electronic system was used for 3D motion capture as subjects walked barefoot at a self-selected speed on a 10 meter walkway instrumented with three force plates. Data were imported into a 12-body segment multibody dynamics model (AnyBody Technology) to calculate joint forces. Each leg contained 56 muscles whose mechanical effect was modeled by 159 simple muscle slips, each consisting of a contractile element. The models were scaled to match each subject's anthropometry and BMI. For the control subjects, only one limb was used in determining the relationship between body mass and peak joint force at the hip, knee, and ankle. For the TKA subjects, the peak joint forces were calculated for both the TKA limb and the contralateral limb.


Chris Wilson Anneka Stevens Graham Mercer Jegan Krishnan

Alignment and soft tissue balance are two of the most important factors that influence early and long term outcome of total knee arthroplasty.

Current clinical practice involves the use of plain radiographs for preoperative planning and conventional instrumentation for intra operative alignment.

The aim of this study is to assess the SignatureTM Personalised system using patient specific guides developed from MRI. The SignatureTM system is used with the VanguardRComplete Knee System. This system is compared with conventional instrumentation and computer assisted navigation with the Vanguard system.

Patients were randomised into 3 groups of 50 to either Conventional Instumented Knee, Computer Navigation Assisted Knee Arthroplasty or Signature Personalised Knee Arthoplasty. All patients had the Vanguard Total knee Arthroplasty Implanted.

All patients underwent Long leg X-rays and CT Scans to measure Alignment at pre-op and 6 months post-op. All patients had clinical review and the Knee Society Score (KSS) at 1 year post surgery was used to measure the outcome.

A complete dataset was obtained for 124 patients. There were significant differences in alignment on Long leg films ot of CT scan with perth protocol. Notably the Signature group had the smallest spread of outliers.

In conclusion the Signature knee system compares well in comparison with traditional instrumentation and CAS Total Knee Arthroplasty.


Chris Wilson

Background

Total knee arthroplasty is associated with early postoperative pain. Appropriate pain management is important to facilitate postoperative rehabilitation and positive functional outcomes. This study compares outcomes in TKA with three techniques; local infiltration analgesia, single shot femoral nerve block and intrathecal morphine.

Methods

Forty-five patients undergoing elective primary Total Knee Arthroplasty (TKA) with were randomized into one of three groups in a double blind proof of concept study. Study arm 1 received local infiltration analgesia ropivacaine intra-operatively, an elastomeric device of ropivacaine for 24 hours post-op. Study arm 2 received a femoral nerve block of ropivacaine with placebo local infiltration analgesia and placebo intrathecal morphine. Study arm 3 received intrathecal morphine, placebo femoral nerve block and placebo local infiltration analgesia. All patients received standardized pre-operative, intraoperative and Post-operative analgesic medication.

Participants were mobilized at 4 hrs, 24hrs and 48 hrs post operation. Range of Motion, Visual Analogue Scale (VAS) pain intensity scores and two minute walk test and Timed Up and Go test were performed. Postoperative use of analgesic drugs was recorded. Knee Society Score (KSS), Oxford Knee Score and Knee Injury and Osteoarthritis Outcome Score (KOOS) were completed at preoperative and 6 weeks post op.


Amy Watts Ben Williams Jegan Krishnan Chris Wilson

Background

Shoulder impingement syndrome (SIS) is a common debilitating condition, treated across multiple health disciplines including Orthopaedics, Physiotherapy, and Rheumatology. There is little consistency in diagnostic criteria with ‘Shoulder impingement syndrome’ being used for a broad spectrum of complex pathologies. We assessed patterns in diagnostic procedures for SIS across multiple disciplines.

Methods

This is a systematic review of electronic databases MEDLINE, PubMed, The Cochrane Library, Embase, Scopus and CINAHL five years of publications, January 2009 - January 2014. Search terms for SIS included subacromial impingement syndrome, subacromial bursitis. Searches were delimited to articles written in English. The PRISMA guidelines were followed. Two reviewers independently screened all articles, data was then extracted by one reviewer and twenty percent of the extraction was independently assessed by the co-reviewer. Studies included were intervention studies examining individuals diagnosed with SIS and we were interested in the process and method used for the diagnosis.


Markus Wimmer Carol Pacione Michel Laurent Susan Chubinskaya

Introduction

Currently, there is a focus on the development of novel materials to articulate against cartilage. Such materials should either eliminate or delay the necessity of total joint replacement. While cobalt-chromium (CoCr) alloy is still a material of choice and used for hemi-arthroplasties, spacers, and repair plugs, alternative materials are being studied. Pyrolytic carbon (PyC) is a biocompatible material that has been available since the 1980s. It has been widely and successfully used in small joints of the foot and the hand, but its tribological effects in direct comparison to cobalt-chromium (CoCr) remain to be investigated.

Methods

A four station simulator (Figure 1), mimicking joint load and motion, was used for testing. The simulator is housed in an incubator, which and provides the necessary environmental conditions for cartilage survival. Articular cartilage disks (14mm in diameter) were obtained from the trochleas of six to eight months old steer for testing and free-swelling controls. Disks (n=8 per material) were placed in porous polyethylene scaffolds within polypropylene cups and mounted onto the simulator to articulate against 28mm balls of either PyC or CoCr. Each ball was pressed onto the cartilage disk with 40N. In order to allow fluidal load support, the contact migrated over the biphasic cartilage with a 5.2 mm excursion. Concomitantly, the ball oscillated with ±30° at 1 Hz. Testing was conducted for three hours per day over 10 days in Mini ITS medium. Media samples were collected at the end of each three hour test. Upon test commencement, media was pooled (days 1, 4, 7, 10) and analyzed for proteoglycans/sGAGs and hydroxyproline. In addition, total material release into media was estimated by determining the dry weight increase of media samples. For this purpose, 1 ml aliquots of fresh and test media were dialyzed, lyophilized and weighed on a high precision balance. Disk morphology and cell viability were histologically examined.


Markus Wimmer Ryan Freed Christoph Daniels Robin Pourzal

Introduction

Current pre-clinical testing is performed using knee wear simulators with standardized walking profiles. Differences in generated damage patterns to those observed on retrieved liners have been explained with the absence of activities other than walking, less severe loading conditions, and a discrepancy in the simulator's tibiofemoral contact mechanics and in vivo knee excursion. While it has been recognized that rotational alignment of the knee may also drive the location and shape of wear scars, to the best of our knowledge this parameter has not been investigated in knee simulator studies.

Methods

Here, we use patient specific gait as input to the simulation to approximate the patient specific contact mechanics. Kinematic and kinetic input data was obtained from gait analysis of a patient with a MGII (Zimmer Inc.) prosthesis at 11 years post-op using the point cluster technique for tibiofemoral kinematics, and a mathematical model for internal force calculations. Using the identical type of prosthesis on the simulator, wear tests were conducted in displacement mode on a closed-loop controlled station. Because x-rays of the patient suggested an internal rotation of the tibial tray, it was varied form 0–10° and the effect on location and wear scar dimension was assessed. Results were compared with the retrieved liner (obtained after 13 years in vivo).


Kotaro Yamakado

Purpose

The purpose of this study was to evaluate the short to mid-term results after hemiarthroplasty with extended head prosthesis (CTA head) for patients with cuff tear arthopathy.

Hypothesis

Favorable pain reduction would be obtained after hemiarthroplasty with the extended head design.


Kengo Yamamoto Wataru Ando Tsuyoshi Koyama Kenji Ohzono

The Taperloc Microplasty stem design was based on that of the Taperloc stem with flat tapered wedge and the distal portion of the Taperloc stem was shortened by 35mm.

We report the minimum two-year follow up (mean, 26 months) of 68 primary total hip arthroplasty using the Taperloc Microplasty stem. 39 Magnum acetabular cups and 29 M2a Taper acetabular cups were inserted with metal on metal articulation. The series comprised 67 patients (20 men, 47 women) with a mean age at operation of 65 years (31 to 85). The principal diagnosis was osteosrthritis.

Their mean JOA Hip Score improved significantly from 36 points preoperatively to 96 points at two-year follow up. Radiological asseement showed good bony stability in all implants. There was one case of post operative anterior dislocation. We did not see intra-operative fracture previously reported for this implant. There were no clinical and radiological complications related to MOM articulation.

This short-term follow up study demonstrates that the clinical outcome of the Tapeloc Microplasty stem is comparable with that of standard Taperloc stem and other flat taper wedge stems.


Shihori Yamane Masayuki Kyomoto Kenichi Watanabe Toru Moro Yoshio Takatori Sakae Tanaka Kazuhiko Ishihara

To prevent aseptic loosening resulting from osteolysis induced by polyethylene (PE) wear particles in THA, it is necessary to develop a high wear-resistance bearing material. We have investigated the bearing surface mimicking the articular cartilage; grafting a biocompatible polymer, poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), onto the PE surface. High wear-resistance of PMPC-grafted surface has been revealed in the hip simulator wear test of 20 million cycles. Additionaly, in THA, oxidation degradation induced by residual free radicals resulting from gamma-ray irradiation for cross-linking or sterilization is also regarded as serious issue. Recently, gas plasma (GP) sterilization has been used as a less residual radical sterilization method. In this study, we ask a question: the GP sterilization would affect to PMPC surface and/or PE substrate? Hence, we investigated surface chemical, wear, mechanical, physical and oxidation properties of GP sterilized PMPC-grafted highly cross-linked PE (CLPE).

GP-sterilized CLPE and PMPC-grafted CLPE (CLPE (GP) and PMPC-CLPE (GP), respectively; GUR 1020 resin, 75 kGy irradiation), and 25 kGy-gamma-sterilized PMPC-grafted CLPE (PMPC-CLPE (g); GUR 1020 resin, 50 kGy irradiation) were evaluated. Surface property of PMPC layer was evaluated by X-ray photoelectron spectroscopy (XPS), fourier-transform infrared (FT-IR) spectroscopy, fluorescence microscope and cross-sectional transmission electron microscope (TEM) observations. Wettability and lubrication of the PMPC-CLPE surface were evaluated by static water contact angle measurement and ball-on-plate friction test, respectively. Wear properties of the acetabular cups were examined by using hip simulator in the combination with Co-Cr-Mo femoral heads. To evaluate the GP sterilization effect to the CLPE substrate, tensile test, izod impact test, small punch test, gel content, residual radical concentration and oxidation degradation were conducted. Oxidation degradation was evaluated as oxidation index by using a FT-IR spectroscopy.

By the XPS and FT-IR measurements, phosphorus peak and P-O peak attributed to grafted PMPC were observed, respectively. Uniform PMPC layer (100–200 nm thick) was observed on both surfaces of PMPC-CLPE (g) and PMPC-CLPE (GP) [Fig. 1]. Water contact angle of CLPE (GP) was almost 100 degree, while those for PMPC-CLPE (g) and PMPC-CLPE (GP) decreased dramatically to almost 10 degree. Dynamic coefficient of friction of PMPC-CLPE (g) and PMPC-CLPE (GP) was lower than that for CLPE (GP). In the hip simulator wear test, PMPC-CLPE (g) and PMPC-CLPE (GP) cups showed significantly lower amount of wear than that of CLPE (GP) [Fig. 2]. The number of the wear particles was extremely less in PMPC-CLPE (g) and PMPC-CLPE (GP), though the size was not different of all cases. Water thin film might be formed at the grafted PMPC layer, which acted as significantly efficient lubricant. There was no difference in the mechanical and physical properties among three groups. Oxidation index for PMPC-CLPE (GP) after acceleration of aging was lower than that of PMPC-CLPE (g). The GP sterilization might affect only to the PMPC-grafted surface, whereas gamma irradiation affects also to the PE substrate.

From these results, the PMPC-CLPE (GP) is expected to be one of the great bearing materials having not only high-wear resistance but also high-oxidation resistance, which could give further longevity of implantation.


Takuma Yamasaki Yuji Yasunaga Mitsuo Ochi

Introduction

Clione Anchored Replacement Prosthesis (CARP-H system) is a novel femoral implant for cementless fixation at the metaphysis of the proximal femur and preservation of cancellous bone of the femoral diaphysis is expected (Fig.1). We developed CARP-H system and started to use the prosthesis after the approval by Pharmaceuticals and Medical Devices Agency in 2012. This study examines the efficacy and short-term outcome of CARP-H system in a series of patients undergoing total hip arthroplasty (THA) or bipolar hemi-arthroplasty (BHA).

Patients and Methods

Seventeen patients (17 hips) of osteonecrosis of the femoral head (ON) or osteoarthritis of the hip (OA) were included. The diagnoses were OA in 10 patients, and ON in 7 patients. The mean age at surgery was 55 years (35–62 years). The mean follow-up was 12 months (6–19 months). THA using CARP-H system was performed in 11 hips and BHA in 6 hips.


Jae-Hyuk Yang Jung-Ro Yoon

The purpose of this prospective randomized study was to compare the visible, hidden, total blood loss and postoperative haemodynamic change of subcutaneous and intra-articular indwelling closed suction drainage method after total knee arthroplasty (TKA). Patients with primary osteoarthritis, who underwent unilateral TKA were enrolled; Group A with subcutaneous (n=78) and group B with intra-articular (n=79) indwelling closed suction drainage method. Total blood loss, visible blood loss, internal blood loss, postop (day 1), 5th, 10th day hemoglobin, hematocrit levels were compared. Allogenic blood transfusion rate and complications related to soft tissue hematoma formation were additionally compared. Subcutaneous indwelling closed suction drainage method reduced both the visible blood loss and total blood loss (hemovac drainage + internal blood loss) thus decreasing the rate of allogenic transfusion. Although the minor complications such as the incidence of bullae formation and the ecchymosis were higher in the subcutaneous indwelling group, the functional outcome at postoperative 2 year did not demonstrate difference from intra-articular drainage group.


Jae-Hyuk Yang Jung Ro Yoon

Purpose

In vivo comparative gap measurements were performed in 3 different patella positions (reduced, subluxated and everted) using offset-type-force-controlled-spreader-system.

Methods

Prospectively, 50 knees were operated by TKA using a navigation-assisted gap balancing technique. The offset-type-force-controlled-spreader-system was used for gap measurements. This commercially-available instrument allows controllable tension in patella reduced position. The mediolateral gaps of knee extension (0°) and flexion (90°) angle were recorded in 3 different patella positions; reduced, subluxated and everted. Any gap differences of more than 3 mm were considered as a meaningful difference. Correlation between the difference with the demographic data, preoperative radiologic alignment and intraoperative data was analyzed. For statistical analysis, ANOVA and Pearson correlation test were used.


Chyun-Yu Yang

Total knee replacement is a standard procedure for the end-staged knee joints. The main concerns at the perioperative period are infection prophylaxis, pain control, and blood loss management. Several interventions are designed to decrease the blood loss during and after the operation of total knee arthroplasty.

In the recent meta-analysis showed that early tourniquet release of the tourniquet for hemostasis increased the total measured blood loss with primary TKR about 228.7 ml. So, Intra-operative blood loss for hemostasis can be saved by not to release the tourniquet after implants fixation, irrigation, closure of the wound and the application of compression dressing.

Our study showed that most of the post-operative blood loss was collected during the first few postoperative hours: 37% in the first 2 hours and 55% in the first 4 hours and 82.1% in the first 24 hours. So, clamping the drainage for the first 4 postoperative hours would reduce blood loss after TKA (518 v.s. 843 mL). The fall in hemoglobin and Hct are also of significant difference (1.64 vs. 2.09 for Hb; 5.18 vs.7.69 for Hct).

Appropriate clamping for an optimal time may be the most economical and simple, and the benefits of clamping also appear to outweigh its potential risks.

NO DRAIN at all is able to reduce the post-operative blood loss. Our study showed that the decrease of postoperative hemoglobin was significantly less than that in no-drain group (1.45±0.72 vs 1.8±0.91). Shorter hospital stay was achieved in the no-drain group (8.3 ± 2.6 vs 10.7±3.2 days). All patients achieved good range of motion (flexion: 0 to >90 degree)by the five days after operation and no prosthetic infection was noted during follow-up. Thus, the routine use of closed suction drains for elective minimal-invasive total knee arthroplasty is not recommended.


Chyun-Yu Yang Chih-Wei Chang

TKR is a standard procedure for knee joint falure. Besides surgical technique, the main concerns at the perioperative care are: infection prophylaxis, blood loss management, & pain control. Pain is a normal part during the post-operative recovery stage.

Currently, I apply multimodal pain control cocktails: Parenteral narcotics (as pethidine, tramadol, morphine), oral analgesics (as NSAIDs, Acetaminophen, opioids), PCA (Patient controlled analgesia), LIA (local IA injection anesthetics, Marcaine), and immediate Ice Packing.

How about the usage of transdermal, non-opioid devices as Lidocaine patch. It shows the advantages of: less invasiveness, less ambulation-impeding, easy monitor & control, patient-activated, and absence of opioid-induced complications. Also it can be an adjuvant in the multi-modal anesthesia.

In this Randomized prospective study, we investigate the analgesic effects of various transdermal non-opioid patches in patients after elective TKR

Conclusion

The use of non-opioid transdermal patches is a safe and patient-activated method. Non-opioid transdermal patches show NSD improvement in the postoperative pain control for patients underwent TKA, facilitating fewer narcotics consumption, fewer breakthrough pain, faster recovery in movements and even shorter stay. However, without obvious differences, the routine use of transdermal patches in current pain control protocol should be trade-off.


Seido Yarimitsu Ayumi Yoshida Kazuhiro Nakashima Yoshinori Sawae Teruo Murakami Saori Sasaki Atsushi Suzuki

Poly (vinyl alcohol) (PVA) hydrogel with high water content is one of the potential materials for artificial cartilage. In the previous study, the wear behavior of PVA hydrogel prepared by freeze-thawing (FT) method (PVA-FT gel) showed the excellent friction and wear property in simulated biological environment. However, the improvement of mechanical strength and wear resistance would be also needed for clinical application of PVA hydrogel as artificial cartilage. The different kind of physically-crosslinked PVA hydrogels prepared by cast-drying (CD) method (PVA-CD gel) and hybrid method of FT and CD (PVA-CD on FT hybrid gel) were also developed, and these two hydrogels have different mechanical properties and showed low friction compared with PVA-FT gel in saline. In this study, PVA hydrogel prepared by CD and hybrid methods were newly developed and friction and wear behavior of PVA-CD gel and PVA-CD on FT hybrid gel were evaluated in simulated biological environment.

A sliding pair of an ellipsoidal reciprocating upper specimen of hydrogel and a flat stationary lower specimen of hydrogel was tested in reciprocating friction test. The thicknesses of PVA-CD gel and PVA-CD on FT hybrid gel were 2.0mm and 1.7mm, respectively. The applied load was 2.94 N. The sliding velocity was 20 mm/s and the total sliding distance was 1.5 km. In this study, solutions that contain hyaluronic acid, phospholipid and proteins were prepared as simulated synovial fluid and used as a lubricant for friction test. Molecular weight of sodium hyaluronate was 9.2×105. L-alpha dipalmitoylphosphatidylcholine (DPPC) was selected as phospholipid constituent and was dispersed in saline as liposome. This liposomal solution was used as a base lubricant. Albumin and gamma-globulin, which are main protein constituents in natural synovial fluid, were used as additives as protein constituents.

As shown in Fig.1, PVA-CD gel showed low friction such as below 0.02 at initial state of friction test. However, friction coefficient of PVA-CD gel rapidly increased and reached to about 0.5. In contrast, PVA-CD on FT hybrid gel kept low friction within the friction test. After friction test, many deep scratches were observed on the worn surface of PVA-CD gel (Figs. 2(a)-(c)). In contrast, the original surface structure of PVA-CD on FT hybrid gel almost remained while some scratches were observed (Figs. 2(d)-(f)).

These results indicated that PVA-CD gel could show low friction but low wear resistance. The hybridization of FT and CD improved the wear resistance of PVA-CD gel. Therefore, the hybridization of FT and CD method is one of the prospective preparation methods of artificial cartilage with low friction and low wear. It is important to elucidate the mechanism of excellent lubricating property of PVA-CD on FT hybrid gel and develop the highly-functioned artificial hydrogel cartilage with low friction and high wear resistance.


Yukio Yonemoto Koichi Okamura Kimihiko Takeuchi Takafumi Hosokawa Tetsuya Kaneko Masatoshi Matsushita Chisa Okura Tsutomu Kobayashi Kenji Takagishi

Background

Previously, the Coonrad-Morrey elbow system has typically been performed using linked-type total elbow arthroplasty (TEA) implants. However, this implant have been reported to be associated with some problems, such as wearing down, loosening, the complexity of the necessary surgical techniques and inappropriate implant size for Asian people.

The Discovery elbow system (Biomet Inc., Warsaw, US) has recently been developed and it has many advantages when compared to Coonrad-Morrey implant, but the treatment outcome for this system is unclear in patients with rheumatoid arthritis (RA).

Objectives

The aim of this study was to clarify the outcome of TEA using the Discovery elbow system.


SungHwan Yoon

Introduction

In total knee arthroplasty, the alignment of leg depends on the alignment of the component. In unicompartmental knee arthroplasty, it is determined by the thickness of the implant relative to the bone excised mostly. After initial scepticism, UKA is increasingly accepted as a reliable procedure for unicompartmental knee osteoarthritis with the improvements in implant design, surgical technique and appropriate patient selection. Recently, computer assisted UKA is helpful in accuracy and less invasive procedure. But, fixed bearing or mobile bearing in UKA is still controversy. We compared the early clinical and radiological results of robot-assisted unicompartmental knee arthroplasty using a fixed bearing design versus a mobile type bearing design.

Materials and Methods

A data set of 50 cases of isolated compartmental degenerative disease that underwent robot-assisted UKA using a fixed bearing design were compared to a data set of 50 cases using a mobile bearing type design. The operations were performed by one-senior author with the same robot system. The clinical evaluations included the Knee Society Score (knee score, functional score) and postoperative complications. The radiological evaluations was assessed by 3-foot standing radiographs using the technique of Kennedy and White to determine the mechanical axis and femoro-tibial angle for knee alignment. Operative factors were evaluated including length of skin incision, operation time, blood loss, hospital stay and intraoperative complications.


Hiroyuki Yoshii Kazuhiro Oinuma Tatsuya Tamaki Kurato Jonishi Yoko Miura Hideaki Shiratsuchi

Purpose

Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire (JHEQ) is subjective assessment of coxarthropathy and reflects the satisfaction level of the patient. Recently, the use of JHEQ as a postoperative assessment of total hip arthroplasty (THA) has become widespread. The aim of this study was to investigate the clinical outcomes of bilateral simultaneous THA through the direct anterior approach (DAA) using JHEQ.

Methods

This study included 34 patients (41 hips) who were treated with first THA at our hospital from January to March 2013 and were available for evaluation of clinical outcomes 1 year after surgery. Of these, 7 (2 males and 5 females; mean age, 54.7 years) underwent bilateral simultaneous THA (group B), and 27 (2 males and 25 females; mean age, 64.2 years) underwent unilateral THA (group U). Thirty patients were preoperatively diagnosed with hip osteoarthritis, and 4 were diagnosed with avascular necrosis of the femoral head. All patients were treated through DAA in a supine position under general anaesthesia. Items for evaluation included clinical outcomes, Japanese Orthopaedic Association Hip score (JOA score) and JHEQ.


Eiji Yoshimoto

Introduction

Unicompartmental knee arthroplasty(UKA) has become a popular treatment alternative when one compartment of the knee is affected. Excellent intermediate results have been reported in association with the Miller-Galante unicompartmental implant. These excellent results are based on the development of the implants and the stringent patients selection. The functional cruciate ligaments has been a prerequisite for patients undergoing UKA. However, UKA can be one of the procedures in elderly patiants with deficient anterior cruciate ligaments(ACL) but with no symptoms of instability. The purpose of this report is to determine the clinical results after UKA in patients with ACL-deficient knees and compared those after UKA in ACL-intact knees.

Patients and Methods

We identified 332 cases operated from May 2000 to April 2013 whose ACL were evaluated before the operation by MRI., and classified into ACL-deficient group and ACL-intact group. Fixed-bearing Miller-Galante Unicompartmental Knee System or Zimmer Unicompartmental High-Flex Knee Sytem was implanted in all patients. ACL-deficient group included 17 men and 68 women who had an average age of 79 years(range, 70–91 years) at the time of the operation. The underlying diagnosis was osteoarthritis for 77 knees and osteonecrosis for 8 knees. ACL-intact group included 49 men and 198 women who had an average age of 77 years(range, 60–88 years) at the time of the operation. The underlying diagnosis was osteoarthritis for 176 knees and osteonecrosis for 71 knees. Followup for ACL-deficient group was 3.5 years(1–8.8years), and 3.6years (1–13.2years) for ACL-intact group.


Sung-Do Cho Yoon-Seok Youm Jong-Hyun Kim

Purpose

To measure the vitamin D level of the patients who received total knee arthroplasty (TKA) and evaluate the effect of vitamin D level on the results of TKA.

Materials and Methods

From February 2012 to January 2013, 151 female patients (204 knees) who underwent primary TKA by one surgeon were included in our study. Preoperative vitamin D level was measured and analyzed the relationship between that and preoperative Visual Analogue Scale (VAS), and Knee Society Knee Score (KS) and Function Score (FS). Thirty-nine patients (39 knees) who received unilateral TKA and could be followed up more than 1 year after operation were evaluated for the relationship between vitamin D level and postoperative VAS, KS and FS, and Western Ontario and McMaster Universities Arthritis Index (WOMAC) score.


Matteo Moretti Arianna Lovati Giuseppe Talo Davide Mercuri Francesco Segatti Luigi Zagra

INTRODUCTION

Trabecular Titanium (TT) is a novel material with a structure similar to trabecular bone, already used for prosthetic clinical applications. Being the bone-implant interface the weakest point during the initial healing period, the association of TT with a hydrogel enriched with progenitor cells and osteoinductive factors may represent a promising strategy to improve prosthesis osteointegration. In a previous in vitro study we evaluated the ability of an ammidated carboxymethylcellulose hydrogel (CMCA) and of TT enriched with CMCA to support bone marrow mesenchymal stem cells (BMSCs) viability and osteogenic differentiation [1]. The aim of this study was to evaluate in vivo if the association of TT with CMCA enriched with strontium chloride (SrCl2) and BMSCs could ameliorate TT osteointegration.

METHODS

This study combines TT with CMCA, SrCl2 and BMSCs. To mimic prosthesis-bone implants, TT discs were seeded with human BMSCs predifferentiated in osteogenic medium, then press-fit into engineered bone. A total of 36 athymic mice were implanted subcutaneously, each animal received 2 constructs as un-seeded TT and TT+CMCA or cell seeded TT+BMSCs and TT+CMCA+BMSCs. After 4, 8 and 12 weeks, osteodeposition, bone mineral density (BMD) and osteointegration were evaluated by fluorescence imaging, micro-CT, SEM, histology and pull-out tests.


Mark William Zawadsky Richard Verstraete

Introduction

Allogeneic blood transfusion (ABT) remains a widely used therapeutic intervention in patients undergoing total knee arthroplasty (TKA). There is mounting evidence that tranexamic acid (TXA), a powerful antifibinolytic, can significantly reduce perioperative blood loss with a concomitant lower ABT rate. In May 2012, TXA intravenous infusion was introduced as standard therapy in all patients undergoing major hip and knee arthroplasty. The TXA protocol included infusing 1 gm prior to incision and 1 gm after lowering the tourniquet. Nadir hemoglobin (Hb) level has been shown to be the single most important predictor of ABT in patients undergoing TKA. It is often used as the main trigger for ABT and in research trials examining restrictive transfusion trials. There is a paucity of information regarding the impact of TXA on Hb levels in patients undergoing primary TKA. The purpose of this retrospective study was to examine the impact of TXA on hemoglobin levels in primary TKA patients.

Methods

Patients undergoing primary single, or bilateral, TKA from a single orthopedic surgeon from the years 2009–2010 before TXA infusion (n=78) were compared to patients undergoing the same operation after TXA was introduced as a therapeutic intervention (n=97). TKA is a very standardized operation that has stayed consistent over the convening years in terms of surgical technique and intra-operative management. The following Hb values were selected for analysis between the two groups: pre-surgical Hb value, immediate post-operative Hb, nadir Hb, and discharge Hb. Paired t-test was used for analysis with p-value set at 0.05. Additional data analysis included: length of stay (LOS) and rate of ABT.


Rui Zhou Alexander Glover Kaira Pearson Mohammad Waseem

4 years of follow-up study on 27 patients who had biological reverse total shoulder replacement 12 patients who had Bio-RSA by using Tonier Aequalis reversed implants with bone graft extracted from the head of humerus before humeral shaft was prepared. The average age of this group of patients is 77. The average pre-operative shoulder abduction on the affected side is 52 degrees and forward flexion of 90 degrees. Indication for surgery in all those cases are due to cuff tear. The average post-operative abduction is 90 degrees and forward flexion of 97 degrees. The average follow-up period is 9 months with a range from 4 to 18 months. Two patients from this group failed to make an improvement in the range of their shoulder movements post-operatively.

15 underwent Bio-RSA by using Delta XTEND reverse shoulder system without bone graft. The average age of this group of patients is 73. The average pre-operative shoulder abduction is 35 degrees and forward flexion of 37 degrees. Indication for surgery again in most of the cases is due to cuff tear, except one case was due to proximal humeral fracture. The average post-operative abduction is 96 degrees and forward flexion of 101 degrees. The average follow-up period is 19 months with a range of 4–42 months. Only one patient failed to make an improvement post-operatively. This is the patient who had Bio-RSA due to a proximal humeral fracture. 6 patients out of this group also had previous resurfacing which has failed in comparison to the bone graft group which none had previous resurfacing surgery.

Conclusion

Overall, the average post-operative range of movements in both groups is not very significant different. Bio-RSA without bone graft seems to make a larger improvement when compared with per-operative range of motion. Howver, whether a much longer follow-up period and younger patients have an impact on the outcome is debatable.


Hao Tang Yixin Zhou Dejin Yang Shengjie Guo Jing Tang Jian Liu

Background

The development of T-smart tomosynthesis has greatly improved the imaging quality of THA by reducing the peri-implant artifacts. In order to find out whether these improvements could lead to diagnostic advantages on stability of cementless THA arthroplasty components, we conducted a diagnostic research by comparing T-smart tomosynthesis, X-ray, and computed tomography.

Methods

We retrospectively included 48 patients who undergone THA revisions in our center between Aug, 2013 and Mar, 2014. For patients with hybrid fixation as their primary prosthesis, the femoral or acetabular components with cement fixation were excluded. There were 41 cementless femoral stems and 35 cementless acetabular cups remained for evaluation. All patients took anterior-posterior and lateral view x-ray examination, anterior-posterior T-smart tomosynthesis scan, and computed tomography before revision surgery. As the gold standard, intraoperative pull-out tests and twisting tests were done for every patient to examine the stability of all implants. 7 orthopedic surgeons evaluated the preoperative images independently, who were divided into the senior group (3 doctors with 6∼13 years’ clinical experience) and the junior group (4 doctors with 2∼4 years’ clinical experience). The x-rays were evaluated first, followed by computed tomography 4 weeks later, and after another 4 weeks’ interval the T-smart tomosynthesis were assessed. All doctors used the same criteria for diagnosis. Diagnostic accuracy for each imaging examination was calculated by comparing with the results of intraoperative tests. The diagnostic accuracy, kappa values between 3 imaging techniques were calculated, and chi-square tests were conducted to examine the difference between the senior and junior groups for each technique.


Hendrik Zuiderbaan Saker Khamaisy Ran Thein Danyal H. Nawabi Harshvardhan Chawla Joseph Nguyen Andrew Pearle

Introduction

There are several advantages of unicompartmental knee arthroplasty (UKA) in the treatment of isolated compartment osteoarthritis (OA) compared to the conventional total knee arthroplasty. Although various series report similar survivorship results, the national registries tend to show higher revision rates among the UKA. Persisting, unexplainable pain is a leading cause for UKA revision surgery. Therefore it is essential to investigate the various patient specific characteristics which might influence outcome following UKA in order to minimize revision rates and optimize clinical outcomes. The purpose of this study is to evaluate the influence of the various individual patient factors, including pre-operative radiographic parameters, on the outcome following UKA.

Methods

168 consecutive patients who underwent robot assisted UKA (MAKO Tactile Guidance System, MAKO Surgical Corporation, Ft. Lauderdale, FL, USA) were included. The investigated pre- and/or postoperative parameters included gender, BMI, age, type of tibial implant (inlay versus onlay), laterality, state of OA (i.e. Kellgren and Lawrence grade) of the operated and non-operated compartment and mechanical axis alignment.

Pre-operatively and at a minimum of 1 year (average 1.97 years, range 1 – 4.2 years) following surgery, patients were asked to complete the Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire. It is subdivided in three separate scales (i.e. pain, stiffness and function). A score of 0 represents the best possible outcome and a score of 100 the worst. A p-value <0.05 was considered statistically significant.


Hendrik Zuiderbaan Saker Khamaisy Ran Thein Danyal H. Nawabi Andrew Pearle

Introduction

Chronic uneven distribution of forces over the articular cartilage, which are present in OA, has been shown to be a risk factor for the development of OA. Certain regions of the articular cartilage will be exposed to increased chronic peak loads, whereas other regions encounter a corresponding relative reduction of transmitted forces. This has a well known influence on cartilage viability and is a precursor of degenerative progression. Congruence of joints has an important impact on force distribution across articular surfaces. Therefore, tibiofemoral incongruence could lead to alterations of load distribution and ultimately to progressive degenerative changes. In clinical practice the routine method for evaluation of progressive OA is analysis of joint space width (JSW) using weight bearing radiographs. Recent studies have suggested that JSW has a strong positive correlation with cartilage compression, volume and meniscal extrusion

Lateral unicondylar knee arthroplasty (UKA) has gained increasing popularity over the last decade in the treatment of isolated unicompartmental osteoarthritis (OA). However, progressive degenerative alterations of the medial compartment following lateral unicompartmental knee arthroplasty remains a leading cause of revision surgery. Therefore, the purpose of this study is to evaluate the medial compartment congruence (MCC) and joint space width (JSW) alterations following lateral UKA.

Methods

The MCC of 53 knees following lateral UKA was evaluated on pre- and postoperative radiographs and compared to 41 healthy knees, using an Interative Closest Point (ICP) algorithm. The ICP algorithm calculated the Congruence Index (CI) by performing a rigid transformation that best aligns the digitized tibial and femoral surfaces (figure 1A). Inner, middle and outer JSW was measured by subdividing the medial compartment into four quarters on weight bearing tunnel view radiographs pre- and postoperatively (figure 1B).


Hendrik Zuiderbaan Saker Khamaisy Ran Thein Danyal H. Nawabi Chad Ishmael Sophia Paul You-Yu Lee Andrew Pearle

Introduction

Historically, the outcomes of knee replacement were evaluated based on implant longevity, major complications and range of motion. Over the last recent years however, there has been an intensively growth of interest in the patient's perception of functional outcome. However, the currently used patient related outcome (PRO) scores are limited by ceiling effects which limit the possibility to distinguish between good and excellent results post knee arthroplasty. The Forgotten Joint Score (FJS) is a new PRO score which is not influenced by ceiling effects, therefore making it the ideal instrument to compare functional outcome between various types of implants. It is based on the thought that the ultimate goal in joint arthroplasty is the ability of a patient to forget their artificial joint in everyday life.

The aim of this study is to compare the FJS between patients who undergo TKA and patients who undergo medial UKA at least 12 months post-operatively. We hypothesized that the UKA which is less extensive surgical procedure will present better FJS than TKA, even 12 month postoperative.

Methods

All patients who underwent medial UKA or TKA were contacted 12 months post-operatively. They were asked to complete the FJS, the Western Ontario and McMasters Universities Osteoarthritis index (WOMAC) and the EuroQol-5D (EQ-5D). A priori power analysis was conducted using two-sample t-test. 64 patients in each group were needed to reach 80% power for detecting a 12 point (SD 24) significant difference on the FJS scale with a two-sided significant level of 0.05. A p-value <0.05 was considered as statistically significant.