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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_16 | Pages 37 - 37
1 Oct 2014
Hirao M Tsuboi H Akita S Matsushita M Ohshima S Saeki Y Murase T Hashimoto J
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When total ankle arthroplasty (TAA) is performed, although tibial osteotomy is instructed to be perpendicular to long axis of tibia, there is no established index for the talar bone corrective osteotomy. Then, we have been deciding the correction angle at the plan for adjustment of the loading axis through whole lower extremities. We studied 17 TAA cases with rheumatoid arthritis (RA). X-ray picture of hip to calcaneus view (hip joint to tip of the calcaneus) defined to show more approximated loading axis has been referred for the preoperative planning. Furthermore, the data of correction angle has been reflected to pre-designed custom-made surgical guide. If soft tissue balance was not acceptable, malleolar sliding osteotomy was added. The distance between the centre of ankle joint and the axis (preD) was measured (mm) preoperatively, and the distance between the centre of prosthesis and the axis (postD) was measured postoperatively. Next, the tilting angle between tibial and talar components (defined as the index of prosthesis edge loading) were measured with X-rays during standing. Tibio Calcaneal (TC) angle was also measured pre and postoperatively.

TC angle was significantly improved from 8.3±6.0° to 3.5±3.6° postoperatively (P=0.028). PreD was 12.9±9.6mm, and that was significantly improved to 4.8±6.3mm (postD) (P=0.006). Within 17 cases, 8 cases showed 0–1mm of postD, 4 cases showed 1–5mm of postD, remaining 5 cases concomitant subtalar fusion with severe valgus and varus hindfoot deformity showed over 8mm of postD. All of the 12 cases showing within 5mm of postD indicated within 13mm of preD. The tilting angle between components was 0.17±0.37° postoperatively.

Taken together, pre-designed corrective talar osteotomy based on preoperative planning using hip to calcaneus view was useful to adjust the mechanical axis for replaced ankle joint in RA cases. Furthermore, after surgery, the hip to calcaneus view was useful to evaluate post-operative mechanical axis of whole lower extremities.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 432 - 432
1 Nov 2011
Takahashi Y Pezzotti G Kakimoto A Hashimoto J Sugano N
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Multiaxial rotation of femoral component is generated in a wide range against UHMWPE tibial insert during ambulation or deep bending activities. Simultaneously, microscopic oscillation and twisting might accompany with such a wide-range motion.

Such a combined in-vivo kinetics is expected to bring more severe wear to the sliding surface of knee joint prostheses than that in a case of single macro-kinetics (i.e., that commonly reproduced by conventional wear simulators). In order to reproduce clinical surface degradation correctly and quantitatively in simulator tests, we have to consider microscopic motions at the joint bearing surfaces. The purpose of this study is to analyze the influence of the composite knee motion on wear using a non-destructive spectroscopic approach.

The crystalline phase in UHMWPE is pre-oriented in the tibial insert from the manufacturing process, but the orientation of crystalline lamellae is sensitive to mechanical loading. Therefore, the orientation of the crystalline lamellae on the surface of retrieved UHMWPE tibial inserts could reflect the local motions in vivo generated in the joint during ambulation. The visualization of (orthorhombic) crystalline lamellae might ultimately lead to the possibility of tracking back the wear history of the joint. In this study, polarized Raman spectroscopy was employed in order to non-destructively visualize the lamellar orientation in UHMWPE tibial inserts, which were retrieved after exposures in human body elapsing several years.

According to this Raman analysis and in comparison with an unused insert, the orientation of surface lamellae was found to have been clearly changed due to wear in accordance to the local motion of the femoral component. Additionally, we could obtain information about the origin of delamination from the in-depth profile for lamellae orientation angle. This study not only shows the possibility of optimizing the UHMWPE structure to minimize wear but also gives a hint for the development of knee simulators of the next generation.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 4 | Pages 490 - 494
1 Apr 2007
Arimitsu S Murase T Hashimoto J Oka K Sugamoto K Yoshikawa H Moritomo H

We have measured the three-dimensional patterns of carpal deformity in 20 wrists in 20 rheumatoid patients in which the carpal bones were shifted ulnarwards on plain radiography. Three-dimensional bone models of the carpus and radius were created by computerised tomography with the wrist in the neutral position. The location of the centroids and rotational angle of each carpal bone relative to the radius were calculated and compared with those of ten normal wrists.

In the radiocarpal joint, the proximal row was flexed and the centroids of all carpal bones translocated in an ulnar, proximal and volar direction with loss of congruity. In the midcarpal joint, the distal row was extended and congruity generally well preserved. These findings may facilitate more positive use of radiocarpal fusion alone for the deformed rheumatoid wrist.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 209 - 209
1 May 2006
Kuriyama K Hashimoto J Fujii M Murase T Tsuboi H Myoui A Yoshikawa H
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Background: Juxta-articular intraosseous cystic lesions (JAICL) are common lesion in patients with rheumatoid arthritis (RA) and could cause spontaneous pathological fractures and extensive joint destruction. Although surgical treatment is well indicated for benign bone tumour such as solitary bone cyst, RA induced JAICL have been rarely treated surgically because of following reasons. The first is the possible re-absorption of grafted bone due to disease progression. The second is donor site problem of iliac bone autografting. The third is limitation of autograft for possible operations in the future. The fourth is the lack of bone graft substitutes with good osteoconductivity. We have developed the interconnected porous calcium hydroxyapatite ceramic (IP-CHA) with excellent osteoconductivity. The IP-CHA achieved major incorporation with host bone much more rapid than the other porous calcium hydroxyapatite ceramics. We evaluated the feasibility and effectiveness of curettage and packing with the IP-CHA for the treatment of JAICL in RA patients.

Methods: Nine JAICL in 7 RA patients were treated by curettage and packing with IP-CHA. Eight lesions were impending pathological fractures. Two were male and five were female, the average age of operation was 57.8 years (range, forty-nine to seventy-two years). Follow-up assessment was based on final radiography at an average of 10.9 months after surgery (range, five to seventeen months). The expansion of the cystic lesions around the implanted IP-CHA and the re-absorption of the IP-CHA itself, which means erosion or increasing porosity of implanted IP-CHA, were assessed on the basis of the radiographies at just after operation and final follow up.

Results: The locations were as follows: distal radius, 6 lesions; distal ulna, 1; proximal tibia, 1; distal fibula, 1. No lesions showed the re-absorption of implanted IP-CHA itself. One of 9 lesions showed out-expansion of radiolucent area around the implanted IP-CHA without re-absoption of IP-CHA itself at the final follow-up. There were no postoperative fractures as complication.

Conclusions: These results suggested that surgical intervention with the IP-CHA could be useful for prevention of pathological fractures due to arthritis related JAICL. The efficacies of this technique might be augmented by amelioration of disease activity with concomitant drug therapy including biologics, since there was one case with out-expansion of cystic lesions in RA patients.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 80 - 80
1 Jan 2003
Owaki H Hashimoto J Hayashida K Hashimoto H Ochi T Yoshikawa H
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[Objectives] Hallux valgus, dorsal sublaxation or dislocation of metatarsophalangeal joints and clawing of the lateral toes are seen frequently in patients with rheumatoid arthritis (RA). Resection arthroplasty of the metatarsophalangeal joints (MTP joints) are widely used to correct these forefoot deformities and the clinical results are almost good. However lateral toes tend to displace dorsally and painful callosity tends to recur. We used the metatarsal shortening offset osteotomy for shortening and dorsal/medial displacement of the prominent metatarsal head. In this report, we introduce the surgical techniques of shortening offset osteotomy and postoperative changes of plantar pressure measured with F-scan system (Tekscan, Inc. ), and review the short term result during 1 to 4 year follow-up.

[Materials and Methods] This study involved 26 feet of 18 patients with RA which were performed with the metatarsal osteotomy for lateral toes and followed more than 1 year (average follow-up 29 months, range 14–46 months). The average age of the 17 women and 1 man was 61 years (range, 51–77 years). The mean duration from the onset of RA to operation on the forefoot was 17 years (range, 7–42 years). Skin incision was placed on the dorsum of the foot and the extensor digitorum brevis and longus were severed (or elongated). After reposition of MTP joint, transverse osteotomy of distal fifth of the lateral metatarsal bone was performed with resection of few millimeters length metaphysial bone. Cortical bone of the distal end of the proximal stump was chiseled into a small rod between two ditches with rongeur and then the rod was put into medullary canal mortise of distal stump. This procedure make offset shift of metatarsal head medially or dorsally. Swanson implant arthroplasty, distal osteotomy was performed on the great toe. Postoperative clinical and radiological results were evaluated with AOFAS rating system. We measured dynamic plantar pressure before and one year after operation in one representative case.

[Results] At the time of follow-up, the mean AOFAS score was 80 points (59–95) and the mean pain score was 36 points. The recurrence of painful callosity was one case. Nevertheless, the range of motion of the MTP joint remained low: 30 degrees and less in 16 feet (62%) including 3 bony ankylosis of MTP joints. There was no nonunion case. [Discussion]

Resection arthroplasty has been accepted as the treatment of choice for forefoot deformities in RA patients. Recent advance of drug therapy against RA encouraged us to preserve the joint in correction of forefoot deformities. Our technique aimed at preservation of the function of the MTP joints and is suitable for mild deformities in which only one or two rays are involved. Furthermore it is easy to correct the deformity of spray foot and reduce the plantar prominence of metatarsal head. This study revealed the good clinical result in short term follow-up. Although the long term result must to be waited, this method is one of recommendable options for RA patients with forefoot deformities.