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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_18 | Pages 16 - 16
1 Dec 2023
Saghir R Watson K Martin A Cohen A Newman J Rajput V
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Introduction

Knee arthroscopy can be used for ligamentous repair, reconstruction and to reduce burden of infection. Understanding and feeling confident with knee arthroscopy is therefore a highly important skillset for the orthopaedic surgeon. However, with limited training or experience, furthered by reduced practical education due to COVID-19, this skill can be under-developed amongst trainee surgeons.

Methods

At a single institution, ten junior doctors (FY1 to CT2), were recruited as a part of a five, two-hour session, training programme utilising the Simbionix® ARTHRO Mentor knee arthroscopy simulator, supplemented alongside educational guidance with a consultant orthopaedic knee surgeon. All students had minimal to no levels of prior arthroscopic experience. Exercises completed included maintaining steadiness, image centring and orientation, probe triangulation, arthroscopic knee examination, removal of loose bodies and meniscectomy. Pre and post experience questionnaires and quantitative repeat analysis on simulation exercises were undertaken to identify levels of improvement.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 58 - 58
7 Aug 2023
Saghir R Watson K Martin A Cohen A Newman J Rajput V
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Abstract

Introduction

Knee arthroscopy can be used for ligamentous repair, reconstruction and to reduce burden of infection. Understanding and feeling confident with knee arthroscopy is therefore a highly important skillset for the orthopaedic surgeon. However, with limited training or experience, furthered by reduced practical education due to COVID-19, this skill can be under-developed amongst trainee surgeons.

Methods

At a single institution, ten junior doctors (FY1 to CT2), were recruited as a part of a five, two-hour session, training programme utilising the Simbionix® ARTHRO Mentor knee arthroscopy simulator, supplemented alongside educational guidance with a consultant orthopaedic knee surgeon. All students had minimal to no levels of prior arthroscopic experience. Exercises completed included maintaining steadiness, image centering and orientation, probe triangulation, arthroscopic knee examination, removal of loose bodies, and meniscectomy. Pre and post-experience questionnaires and quantitative repeat analysis on simulation exercises were undertaken to identify levels of improvement.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_9 | Pages 14 - 14
17 Apr 2023
Bartolo M Newman S Dandridge O Provaggi E Accardi M Dini D Amis A
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No proven long-term joint-preserving treatment options exist for patients with irreparable meniscal damage. This study aimed to assess gait kinematics and contact pressures of novel fibre-matrix reinforced polyvinyl alcohol-polyethylene glycol (PVA-PEG) hydrogel meniscus implanted ovine stifle joints against intact stifles in a gait simulator.

The gait simulator controlled femoral flexion-extension and applied a 980N axial contact force to the distal end of the tibia, whose movement was guided by the joint natural ligaments (Bartolo; ORS 2021;p1657- LB). Five right stifle joints from sheep aged >2 years were implanted with a PVA-PEG total medial meniscus replacement, fixed to the tibia via transosseous tunnels and interference screws. Implanted stifle joint contact pressures and kinematics in the simulator were recorded and compared to the intact group. Contact pressures on the medial and lateral condyles were measured at 55° flexion using Fujifilm Prescale Low Pressure film inserted under the menisci. 3D kinematics were measured across two 30 second captures using the Optotrak Certus motion-tracking system (Northern Digital Inc.).

Medial peak pressures were not significantly different between the implanted and intact groups (p>0.4), while lateral peak pressures were significantly higher in the implanted group (p<0.01). Implanted stifle joint kinematics in the simulator did not differ significantly from the intact baseline (p>0.01), except for in distraction-compression (p<0.01).

Our findings show that the fibre-matrix reinforced PVA-PEG hydrogel meniscal replacement restored the medial peak contact pressures. Similar to published literature (Fischenich; ABE 2018;46(11):1–12), the lateral peak pressures in the implanted group were higher than the intact. Joint kinematics were similar across groups, with slightly increased internal-external rotation in the implanted group. These findings highlight the effectiveness of the proposed approach and motivate future work on the development of a total meniscal replacement.


Bone & Joint Open
Vol. 3, Issue 8 | Pages 648 - 655
1 Aug 2022
Yeung CM Bhashyam AR Groot OQ Merchan N Newman ET Raskin KA Lozano-Calderón SA

Aims

Due to their radiolucency and favourable mechanical properties, carbon fibre nails may be a preferable alternative to titanium nails for oncology patients. We aim to compare the surgical characteristics and short-term results of patients who underwent intramedullary fixation with either a titanium or carbon fibre nail for pathological long-bone fracture.

Methods

This single tertiary-institutional, retrospectively matched case-control study included 72 patients who underwent prophylactic or therapeutic fixation for pathological fracture of the humerus, femur, or tibia with either a titanium (control group, n = 36) or carbon fibre (case group, n = 36) intramedullary nail between 2016 to 2020. Patients were excluded if intramedullary fixation was combined with any other surgical procedure/fixation method. Outcomes included operating time, blood loss, fluoroscopic time, and complications. Fisher’s exact test and Mann-Whitney U test were used for categorical and continuous outcomes, respectively.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 23 - 23
1 Jul 2022
Frame M Hauck O Newman M
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Abstract

Introduction

Tibial tubercle osteotomy (TTO) is a complex surgical procedure with a significant risk of complications, which include nonunion and tibial fracture. To determine whether an additional suture tape augmentation can provide better biomechanical stability compared with standard screw fixation.

Methods

Five matched pairs of human cadaveric knees were divided into 2 groups: the first group underwent standard TTO fixation with 2 parallel screws. The second group underwent a novel fixation technique, in which a nonabsorbable suture tape (FiberTape) in a figure-of-8 construct was added to the standard screw fixation. Tubercular fragment migration of >50% of the initial distalization length was defined as clinical failure Tubercular fragment displacement during cyclic loading and pull-to-failure force were recorded and compared between the 2 groups.


The Bone & Joint Journal
Vol. 103-B, Issue 6 | Pages 1173 - 1173
1 Jun 2021
Alsousou J Oragui E Martin A Strickland L Newman S Kendrick B Taylor A Glyn-Jones S


The Bone & Joint Journal
Vol. 103-B, Issue 4 | Pages 644 - 649
1 Apr 2021
Alsousou J Oragu E Martin A Strickland L Newman S Kendrick B Taylor A Glyn-Jones S

Aims

The aim of this prospective cohort study was to evaluate the early migration of the TriFit cementless proximally coated tapered femoral stem using radiostereometric analysis (RSA).

Methods

A total of 21 patients (eight men and 13 women) undergoing primary total hip arthroplasty (THA) for osteoarthritis of the hip were recruited in this study and followed up for two years. Two patients were lost to follow-up. All patients received a TriFit stem and Trinity Cup with a vitamin E-infused highly cross-linked ultra-high molecular weight polyethylene liner. Radiographs for RSA were taken postoperatively and then at three, 12, and 24 months. Oxford Hip Score (OHS), EuroQol five-dimension questionnaire (EQ-5D), and adverse events were reported.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_5 | Pages 1 - 1
1 Jul 2020
Fernquest S Palmer A Gimpel M Birchall R Broomfield J Wedatilake T Dijkstra H Lloyd T Pereira C Newman S Carr A Glyn-Jones S
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Background

Cam morphology develops during adolescence and predisposes individuals to future hip pain and osteoarthritis. An improved understanding of cam development is required to determine whether the process is modifiable.

Hypothesis/Purpose

The aim of this study was to characterise the risk factors, timing, and pathogenesis of cam formation.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 83 - 83
1 Feb 2020
Wolff D Newman J Shah N Morrissey P Conway C Gold R Tretiakov M Sedaghatpour D Pivec R Naziri Q Illical E
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Purpose

Infections in orthopaedic surgery are costly, debilitating complications. The search for new treatments and prevention strategies has led to the use of antibiotic-filled calcium sulfate (CaS) as a bone void filler that is both safe and effective. The purpose of this study was to examine the available data on the efficacy of this technology.

Methods

A literature search was performed for studies that evaluated the use of antibiotic-loaded CaS cement in orthopaedics published between inception of the databases to 2017. Selected studies included randomized controlled trials (RCTs) and observational studies published in the English language that met the following criteria: 1) patients underwent an orthopaedic procedure; 2) CaS cement with an antibiotic was used; and 3) at least one of our outcomes were mentioned. Outcomes included resolution of infection, complications related to treatment, subsequent surgeries, overall infection rate, fracture union rate, clinical outcomes, and wound complications. A total of 17 studies were included.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 86 - 86
1 Feb 2020
Khondakar N Shah N Murtaugh T Gold R Aylyarov A Pascal S Harb M Newman J Schwartz J Maheshwari A
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Summary

A meta-analysis was performed to compare rate of SSI after application of chlorhexidine vs. iodine in total joint arthroplasty. Chlorhexidine had significantly lower odds of SSI.

Introduction

Surgical site infections (SSI) are a significant source of morbidity and mortality. The optimal preoperative skin preparation in lower extremity total joint arthroplasty (TJA) remains debatable between chlorhexidine and iodine-containing solutions. This meta-analysis sought compare SSI rates between chlorhexidine cloth application the night before surgery plus povidone-iodine-alcohol (povidone-iodine) solution at surgery or only povidone-iodine at surgery.


The Bone & Joint Journal
Vol. 100-B, Issue 7 | Pages 875 - 881
1 Jul 2018
Newman JM Khlopas A Sodhi N Curtis GL Sultan AA George J Higuera CA Mont MA

Aims

This study compared multiple sclerosis (MS) patients who underwent primary total hip arthroplasty (THA) with a matched cohort. Specifically, we evaluated: 1) implant survivorship; 2) functional outcomes (modified Harris Hip Scores (mHHS), Hip Disability and Osteoarthritis Outcome Score, Joint Replacement (HOOS JR), and modified Multiple Sclerosis Impact Scale (mMSIS) scores (with the MS cohort also evaluated based on the disease phenotype)); 3) physical therapy duration and return to function; 4) radiographic outcomes; and 5) complications.

Patients and Methods

We reviewed our institution’s database to identify MS patients who underwent THA between January 2008 and June 2016. A total of 34 MS patients (41 hips) were matched in a 1:2 ratio to a cohort of THA patients who did not have MS, based on age, body mass index (BMI), and Charlson/Deyo score. Patient records were reviewed for complications, and their functional outcomes and radiographs were reviewed at their most recent follow-up.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 58 - 58
1 Jan 2018
Newman J Khlopas A Sodhi N Curtis G Sultan A Higuera C Mont M
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Patients who have multiple sclerosis (MS) may be at increased risk of developing complications after total hip arthroplasty (THA). The purpose of this study was to compare: 1) implant survivorship; 2) functional outcomes; 3) complication rates; and 4) radiographic findings after THA between MS patients and a matched cohort.

A single institutional database was reviewed for patients who had a diagnosis of MS and underwent a THA. Thirty-four patients (41 hips) were matched to a 2:1 cohort who did not have MS using based on age, sex, body mass index (BMI), and Charlson/Deyo scores. This resulted in a matching cohort of 80 patients (82 hips). The available medical records were reviewed. Functional outcomes and complications were assessed. Postoperative radiographs were evaluated.

The matching cohort had higher all-cause survivorship at 4-years postoperatively (99 vs. 93%). There were 3 revisions in the MS cohort and 0 revisions in the matching cohort. The MS cohort had lower mHHS scores (66 vs.74 points, p<0.001), lower HOOS JR scores (79 vs. 88 points, p<0.01), required more physical therapy (5 vs. 3 weeks, p<0.01), and took longer to return to their baseline functional level (7 vs. 5 weeks, p<0.05). MS patients had higher rate of complications (6 vs. 1, p<0.05). Excluding revision cases, there was no additional radiographic evidence of progressive radiolucency, loosening, or subsidence.

We found that MS patients had lower implant survivorship, lower functional outcome scores, and increased complication rates. These findings may help orthopaedists to have a better knowledge of how MS patients do after THA.


Bone & Joint Research
Vol. 6, Issue 8 | Pages 522 - 529
1 Aug 2017
Ali AM Newman SDS Hooper PA Davies CM Cobb JP

Objectives

Unicompartmental knee arthroplasty (UKA) is a demanding procedure, with tibial component subsidence or pain from high tibial strain being potential causes of revision. The optimal position in terms of load transfer has not been documented for lateral UKA. Our aim was to determine the effect of tibial component position on proximal tibial strain.

Methods

A total of 16 composite tibias were implanted with an Oxford Domed Lateral Partial Knee implant using cutting guides to define tibial slope and resection depth. Four implant positions were assessed: standard (5° posterior slope); 10° posterior slope; 5° reverse tibial slope; and 4 mm increased tibial resection. Using an electrodynamic axial-torsional materials testing machine (Instron 5565), a compressive load of 1.5 kN was applied at 60 N/s on a meniscal bearing via a matching femoral component. Tibial strain beneath the implant was measured using a calibrated Digital Image Correlation system.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_3 | Pages 22 - 22
1 Feb 2017
Huixiang W Newman S Jones G Sugand K Cobb J Auvinet E
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Introduction

Because of the low cost and easy access, surgical video has become a popular method of acquiring surgical skills outside operating rooms without disrupting normal surgical flow. However, currently existing video systems all use a single point of view (POV). Some complex orthopedic procedures, such as joint replacement, require a level of accuracy in several dimensions. So single and fixed POV video may not be enough to provide all the necessary information for educational and training purposes. The aim of our project was to develop a novel multiple POV video system and evaluate its efficacy as an aid for learning joint replacement procedure compared with traditional method.

Materials and Methods

Based on the videos of a hip resurfacing procedure performed by an expert orthopedic surgeon captured by 8 cameras fixed all around the operating table, we developed a novel multiple POV video system which enables users to autonomously switch between optimal viewpoints (Figure 1). 30 student doctors (undergraduate years 3–5 and naive to hip resurfacing procedure) were recruited and randomly allocated to 2 groups: experiment group and control group, and were assigned to learn the procedure using multiple or single POV video systems respectively. Before learning they were first asked to complete a multiple choicetest designed using a modified Delphi technique with the advice and feedback sought from 4 experienced orthopedic surgeons to test the participants' baseline knowledge of hip resurfacing procedure. After video learning, they were asked to answer the test again to verify their gained information and comprehension of the procedure, followed by a 5-point Likert-scale questionnaire to demonstrate their self-perception of confidence and satisfaction with the learning experience. The scores in the 2 tests and in the Likert-scale questionnaire were compared between 2 groups using Independent-Samples t-test (for normally distributed data) or Mann-Whitney U test (for non-normally distributed data). Statistical significance was set as p<0.05.


The Bone & Joint Journal
Vol. 98-B, Issue 7 | Pages 884 - 891
1 Jul 2016
Elliott DS Newman KJH Forward DP Hahn DM Ollivere B Kojima K Handley R Rossiter ND Wixted JJ Smith RM Moran CG

This article presents a unified clinical theory that links established facts about the physiology of bone and homeostasis, with those involved in the healing of fractures and the development of nonunion. The key to this theory is the concept that the tissue that forms in and around a fracture should be considered a specific functional entity. This ‘bone-healing unit’ produces a physiological response to its biological and mechanical environment, which leads to the normal healing of bone. This tissue responds to mechanical forces and functions according to Wolff’s law, Perren’s strain theory and Frost’s concept of the “mechanostat”. In response to the local mechanical environment, the bone-healing unit normally changes with time, producing different tissues that can tolerate various levels of strain. The normal result is the formation of bone that bridges the fracture – healing by callus. Nonunion occurs when the bone-healing unit fails either due to mechanical or biological problems or a combination of both. In clinical practice, the majority of nonunions are due to mechanical problems with instability, resulting in too much strain at the fracture site. In most nonunions, there is an intact bone-healing unit. We suggest that this maintains its biological potential to heal, but fails to function due to the mechanical conditions. The theory predicts the healing pattern of multifragmentary fractures and the observed morphological characteristics of different nonunions. It suggests that the majority of nonunions will heal if the correct mechanical environment is produced by surgery, without the need for biological adjuncts such as autologous bone graft.

Cite this article: Bone Joint J 2016;98-B:884–91.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 30 - 30
1 May 2016
Newman S Clarke S Harris S Cobb J
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Introduction

Patient Specific Instrumentation (PSI) has the potential to allow surgeons to perform procedures more accurately, at lower cost and faster than conventional instrumentation. However, studies using PSI have failed to convincingly demonstrate any of these benefits clinically. The influence of guide design on the accuracy of placement of PSI has received no attention within the literature.

Our experience has suggested that surgeons gain greater benefit from PSI when undertaking procedures they are less familiar with. Lateral unicompartmental knee replacement (UKR) is relatively infrequently performed and may be an example of an operation for which PSI would be of benefit. We aimed to investigate the impact on accuracy of PSI with respect to the area of contact, the nature of the contact (smooth or studded guide surfaces) and the effect of increasing the number of contact points in different planes.

Method

A standard anatomy tibial Sawbone was selected for use in the study and a computed tomography scan obtained to facilitate the production of PSI. Nylon PSI guides were printed on the basis of a lateral UKR plan devised by an orthopaedic surgeon. A control PSI guide with similar dimensions to the cutting block of the Oxford Phase 3 UKR tibial guide was produced, contoured to the anterior tibial surface with multiple studs on the tibial contact surface. Variants of this guide were designed to assess the impact of design features on accuracy. These were: a studded guide with a 40% reduction in tibial contact area, a non-studded version of the control guide, the control guide with a shim to provide articular contact, a guide with an extension to allow distal referencing at the ankle and a guide with a distal extension and an articular shim. All guides were designed with an appendage that facilitated direct attachment to a navigation machine (figure 1). 36 volunteers were asked to place each guide on the tibia with reference to a 3D model of the operative plan. The order of placement was varied using a counterbalanced latin square design to limit the impact of the learning effect. The navigation machine recorded deviations from the plan in respect of proximal-distal and medial-lateral translations as well as rotation around all three axes. Statistical analysis was performed on the compound translational and rotational errors for each guide using ANOVA with Bonferroni correction with statistical significance at p<0.05.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 32 - 32
1 Jan 2016
Carroll K Newman J Holmes A Della Valle AG Cross MB
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Introduction

Stiffness after total knee arthroplasty is a common occurrence. Despite its prevalence, little is known as to which patients are at risk for poor range of motion after total knee arthroplasty. The purpose of this study was to determine the risk factors for manipulation under anesthesia (MUA) after total knee arthroplasty (TKA).

Methods

Using a single institution registry, 160 patients who underwent a manipulation under anesthesia after total knee arthroplasty between 2007 and 2013 were retrospectively evaluated. Each patient was 1:1 matched by age, gender and laterality to a control group of 160 patients who did not require MUA after TKA. Risk factors for MUA were assessed, and included medical co-morbidities, BMI, prior operations, and preoperative range of motion.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_8 | Pages 6 - 6
1 Feb 2013
Granville-Chapman J Nawaz S Trompeter A Newman K Elliott D
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Intramedullary nailing of tibial fractures is commonplace and freehand techniques are increasingly popular. The standard freehand method has the knee of the injured leg flexed over a radio-lucent bolster. This requires the imaging C-arm to swing from antero-posterior to lateral position several times. Furthermore, guide wire placement; reaming and nail insertion are all performed well above most surgeons' shoulder height. If instead the leg is hung over the edge of the table, the assistant must crouch and hold the leg until the nail is passed beyond the fracture.

We describe a method of nailing which is easier both for the surgeons and the (often inexperienced) radiographer and present a series of 87 consecutive cases managed with this technique.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 157 - 157
1 Jan 2013
Nawaz S Keightley A Elliott D Newman K Khaleel A
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Currently the debate continues in definitive fixation method for complex tibial plateau fractures. The aim of surgical management remains prevention of further damage to the articular cartilage, whilst avoiding iatrogenic risks - Low Risk Surgery (LRS). The purpose of this study was to determine the functional impact, clinical radiological outcome following tibial plateau fractures treated with either external fixation or internal fixation.

124 Schatzker IV-VI tibial plateau fractures were reviewed following surgical fixation. Fractures analysed included 24 type IV, 20 type V and 80 type VI tibial plateau fractures. The majority of Schatzker IV fractures were treated with internal fixation, but 67 of 80 Schatzker VI fractures were treated with the Ilizarov method. The average IOWA knee score, was 86 (16 to 100) and the average range of motion was 133 degrees (60 to 150). There were no differences between the circular fixator group and the internal fixation group in terms of range of motion or IOWA scores. There were comparable functional outcomes and complication rates between both groups.

In summary patients with high energy tibial plateau fracture treated with internal or external fixation, have a good chance of achieving satisfactory long term knee function.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 537 - 537
1 Sep 2012
Mohammed R Farook M Newman K
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We reviewed our results and complications of using a pre-bent 1.6mm Kirschner wire (K-wire) for extra-articular metacarpal fractures. The surgical procedure was indicated for angulation at the fracture site in a true lateral radiograph of at least 30 degrees and/or in the presence of a rotatory deformity.

A single K-wire is pre-bent in a lazy-S fashion with a sharp bend at approximately 5 millimetres and a longer smooth curve bent in the opposite direction. An initial entry point is made at the base of the metacarpal using a 2.5mm drill by hand. The K-wire is inserted blunt end first in an antegrade manner and the fracture reduced as the wire is passed across the fracture site. With the wire acting as three-point fixation, early mobilisation is commenced at the metacarpo-phalangeal joint in a Futuro hand splint.

The wire is usually removed with pliers post-operatively at four weeks in the fracture clinic.

We studied internal fixation of 18 little finger and 2 ring finger metacarpal fractures from November 2007 to August 2009. The average age of the cohort was 25 years with 3 women and 17 men. The predominant mechanism was a punch injury with 5 diaphyseal and 15 metacarpal neck fractures. The time to surgical intervention was a mean 13 days (range 4 to 28 days). All fractures proceeded to bony union. The wire was extracted at an average of 4.4 weeks (range three to six weeks). At an average follow up of 8 weeks, one fracture had to be revised for failed fixation and three superficial wound infections needed antibiotic treatment.

With this simple and minimally invasive technique performed as day-case surgery, all patients were able to start mobilisation immediately.

The general outcome was good hand function with few complications.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 29 - 29
1 Jul 2012
Parwez T Hassaballa M Artz N Robinson J Murray J Porteous A Newman J
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Purpose

The aim of this study was to compare the short-term and mid-term outcome of lateral UKRs using a single prosthesis, the AMC Uniglide knee implant.

Methods

Between 2003 and 2010, seventy lateral unicompartmental knee replacements (mean patient age 63.6±12.7 years) were performed at our unit for isolated lateral compartmental disease. Range of knee motion and functional outcome measures including the American Knee Society (AKSS), Oxford (OKS) and WOMAC scores were recorded from 19 knees at five years' post-operatively and compared to 35 knees at two-years and 53 knees at one-year post-op.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 42 - 42
1 Jul 2012
Hassaballa M Murray J Robinson J Porteous A Newman J
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Introduction

Kneeling ability is better in unicompartmental than total knee arthroplasty. There is also an impression that mobile bearing knees achieve better functional outcome than their fixed bearing cousins in unicompartmental and to a lesser extent total joint arthroplasty. In the UK, the market leading unicompartmental replacement is mobile bearing.

Aim

To analyse kneeling ability after total and unicompartmental knee replacement using mobile and fixed bearing inserts.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 45 - 45
1 Mar 2012
Newman J
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Introduction

Trochlear dysplasia (TD) is still poorly recognised, generally considered uncommon and to present purely as persistent patella dislocation.

Diagnosis

87 patients diagnosed as having TD by a true lateral X-ray, MRI scan or at surgery were sent a questionnaire about their initial symptoms. 60% had suffered adolescent anterior knee pain. Lack of trust, wobbling, stair problems, giving way and catching were also common symptoms. Only 66% had ever suffered a dislocation, their troubles had started at 12 years of age. Most had undergone unsuccessful realignment procedures and many had developed premature lateral patello-femoral arthritis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 111 - 111
1 Mar 2012
Pydisetty R Newman J
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Between 1989 and 1992 102 knees adjudged suitable for Unicompartmental replacement (UKR) were randomised to receive either a St Georg Sled UKR or a Kinematic modular total knee replacement (TKR). The early results demonstrated that the UKR group had less complications, and more rapid rehabilitation. At 5 years there were equal failures but the UKR group had more excellent results and a greater range of movement.

Despite this doubt persisted about whether these advantages would be maintained these cases have been followed regularly by a research nurse at 8, 10, 12 years. We now report the final outcome at 15 years. 43 patients (45 knees) have died with all their knees intact. Throughout the review period the Bristol Knee Scores (BKS) of the UKR group have been better and at 15 years 77% and 53% of the surviving UKRs and TKRs achieve an excellent score. 6 TKRs and 4 UKRs have failed during the 15 years of the review.

Conclusion

The better early results with UKR are maintained at 15 years with no greater failure rate. The median BKS scores of the UKR group was 91.1 at five years and 92 at 15 years suggesting little functional deterioration in either the prosthesis or remainder of the joint. These results would seem to justify the increased use of UKR.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 87 - 87
1 Feb 2012
Patel R Stygall J Harrington J Newman S Haddad F
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We aimed to measure cerebral microemboli load during total hip [THA] and knee arthroplasty (TKA) using transcranial Doppler ultrasound (TCD) and to investigate whether cerebral embolic load influences neuropsychiatric outcome. The timing of the microemboli was also related to certain surgical activities to determine if a specific relationship exists and the presence of a patent foramen ovale was investigated.

Patients undergoing primary THA and TKA underwent a battery of ten neuropsychiatric tests pre-operatively and at 6 weeks and 6 months post-operatively. Microembolic load was recorded using TCD onto VHS tape for subsequent analysis. Patent foramen ovale detection was performed using bolus intravenous injection of agitated saline followed by valsalva manoeuvre. The timing of specific surgical steps was recorded for each operation and embolic load calculated for that period. All patients were assessed for quality of life and orthopaedic outcome measures.

Results

45 THA patients and 50 TKA patients were studied. Cerebral microembolisation occurred in 35% of all patients (10 THA patients and 19 TKA patients). Mean microembolic load was 2.8 per patient for THA and 3.76 per patient for TKA patients. PFO was detected in 29 patients overall. Insertion of the femoral component and deflation of the tourniquet were associated with a larger microembolic loads. Neuropsychiatric outcome was not affected by the low embolic loads. Quality of life and Orthopaedic outcome at 6 months was good.

Conclusion

Cerebral microembolisation occurs in a significant proportion of patients during total hip and knee arthroplasty. The presence of a patent foramen ovale does not appear to influence the incidence of microembolisation or load. Specific surgical activities are associated with generating greater embolic loads and methods of avoiding these emboli such as venting the femur may minimise complications and optimise outcomes. Neuropsychiatric outcomes do not seem to be affected by microembolisation of the brain during total joint arthroplasty.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 23 - 23
1 Feb 2012
Johnson S Newman J Jones P
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Background

Unicompartmental knee replacements (UKR) converted to total knee replacements (TKR) have often been viewed with scepticism because of the perceived difficulty of the revision and because revision procedures generally do less well than primaries.

Methods

This is a prospective review of TKRs converted from a UKR between 1982 and 2000. We present the survivorship of a 77 patient cohort and the clinical results of 35 patients. All information was recorded at the time of surgery onto a database and patients have been regularly reviewed since.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 152 - 152
1 Feb 2012
Ackroyd C Newman J Eldridge J Evans R
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Introduction

The Bristol Knee Group has prospectively followed the results of over 500 isolated patellofemoral arthroplasties. Initial experience with the Lubinus prosthesis was disappointing. The main causes of failure were mal-tracking and instability leading to excessive polythene button wear and disease progression in the tibio femoral joint.

This experience resulted in the design of a new prosthesis to correct the tracking problems and improve the wear. We have now performed over 425 Avon arthroplasties with a maximum follow-up of 9 years.

Results

Survivorship at 5 years and the functional outcome have been reported with 95.8% survivorship, and improved function with Oxford score from 18 to 39 points out of 48. There have been 14 cases with mal-tracking (3%). Several of these cases have required proximal or distal realignment with the Elmslie or Insall procedures. Two knees with patella alta required distalisation of the tibial tubercle. Symptomatic progression of the arthritic disease in the medial or lateral tibio-femoral compartments has occurred in 28 cases (7%) causing recurrent joint pain. Radiographic follow-up has shown a higher rate of disease progression emphasising the importance of careful assessment of patients prior to operation.

We have investigated 8 cases of persistent unexplained pain. Analysis of these cases suggests 3 possible causes. An extended anterior cut leading to overstuffing, insufficient external rotation and over sizing of the femoral component leading to medial or lateral retinacular impingement. Six of these cases have been successfully treated by revision of the femoral component leading to dramatic resolution of the symptoms.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 309 - 309
1 Jul 2011
Phadnis J Trompeter A Gallagher K Wan E Elliott D Newman K
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Aim: To assess mid to long-term functional and symptomatic outcome after internal fixation of the distal radius.

Methods: All patients operated upon between June 2004 and October 2007 were retrospectively assessed using the ‘Disabilities of arm, shoulder and hand’ (DASH, range 0–100), and Mayo wrist (range 0–100) functional scoring systems. Fractures were classified according to the AO system. All patients were treated in one unit by the same group of surgeons using standard accepted techniques. Revision operations and patients treated at greater than four weeks after injury were excluded. Radiographic analysis of time to union was also performed.

Results: 201 patients underwent surgical fixation of which, 183 patients were contactable for follow up (9% loss). Only these patients were included in the study. Mean age was 62.5 years. Mean follow up time was 30 months. Mean time to surgery was eight days. 74% had good/excellent Mayo and 75% good/excellent DASH scores. 2% of patients had a poor outcome with both scores. 28 % reported no functional or symptomatic deficit. There was a 14% overall complication rate (6% major). Mean time to union was 8.39 weeks. Time to union increased with advancing AO grade. There was no significant difference in scores with regard to postoperative immobilisation, time to surgery, time to follow up, patient age, surgeon grade or fracture type.

Conclusion: This is one of the largest series of its type and the results compare favourably with other published operative and non-operative treatment modalities. This is a safe, reproducible technique with excellent functional outcome and is recommended as the treatment of choice when surgery is indicated for these fractures.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 541 - 541
1 Oct 2010
Newman J Robinson J
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Background: Although many knee surgeons routinely perform unicompartmental replacement (UKR) for medial compartment arthrosis there is still reluctance to perform lateral UKR’s as they are generally thought to be less satisfactory. The purpose of the present study was to prospectively compare the outcome of lateral UKR’s with medial UKR’s using the AMC Uniglide knee implant.

Methods: Between 2002 and 2005, 29 lateral fixed bearing AMC Uniglide UKR’s were performed at our unit. American Knee Society (AKS), Oxford and WOMAC scores were recorded pre-operatively and at two years post-op and compared with the results of 50 medial mobile bearing and 50 medial fixed bearing AMC Uni-glide UKR’s performed during the same time period. Data was acquired by a research nurse and recorded prospectively on the Bristol Knee Database. The mean ages of the patients were: 63 years in the lateral UKR group was, 62 years in the medial mobile bearing group and 69 in the medial fixed bearing group. The groups were equally sex matched with a predominate number of females in each group. There was no difference between the pre-operative scores for the 3 groups.

Results: At one-year review, the 3 groups had similar mean scores: (table removed)

Conclusions: This study suggests that at two years the quality of outcome of Lateral UKR’s is at least equivalent to both fixed and mobile bearing medial compartment UKR’s. However, continued long-term survivorship studies are needed to assess failure rates of Lateral fixed bearing UKR’s and particularly to evaluate progression of arthritis in the medial compartment. The procedure should form part of the knee surgeons’ armamentarium, but the differences in the operative techniques for lateral and medial UKR must be appreciated.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 541 - 541
1 Oct 2010
Newman J Ackroyd C Robinson J
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Although good long term results for fixed bearing uni-compartmental knee replacements (UKRs) have been reported mobile bearings predominate in some parts of the world. Three prospective studies have been undertaken comparing the short and medium term outcomes of fixed and mobile UKRs.

A 5 year comparative cohort study of 47 Oxford mobile bearing and 57 St Georg Sled fixed bearing UKRs.

A 2 year study of 50 fixed and 50 mobile bearing AMC Uniglide UKRs.(The implant system allows implantation of either a fixed or mobile tibial component with the same femoral component.)

The 1 year results of a randomised controlled trial of 38 fixed and 33 mobile AMC Uniglide UKRs in patients under 70.

In all groups the preoperative sex mix, average age and knee scores were extremely similar.

All patients were assessed both pre and postoperatively by a research nurse and radiographs were taken; the results were entered on the Bristol Knee database.

Results:

Multiple problems were encountered, perhaps because of the introduction of MIS, but at 5 years 11 Oxford and 4 Sleds had failed. The major problem with the mobile bearing implant was instability though tibial fractures were also seen. Both groups had three cases of arthritic progression and loose cement was seen twice in the fixed bearing group.

– Amongst the remaining patients the median scores for the Sled were better. Bristol Knee Score (Max 100) 95:90; Oxford (Max 48) 39:37; and reduced WOMAC (Best score 12) 18:24.

2 bearing exchanges and 3 revisions were needed in the mobile group with none in the fixed group. Again all scores were better for the fixed group. American Knee Score (AKS) (Max 200) 195:185; Oxford (Max48) 39:37; and reduced WOMAC (Max 12) 19:20.

One fixed bearing implant had been revised but none in the mobile group, however 3 randomised to receive a mobile bearing had a fixed bearing inserted because the surgeon was unhappy about bearing stability; all three are doing well. All knee scores at one year show the fixed bearing implant to be performing better. AKS (Max 200) 194:173; Oxford (Max48) 39:33; and WOMAC(Max) 12 18:22.

Conclusion. Although theoretically mobile bearings will give greater longevity there is frequently a short term price to pay particularly when the procedures are performed by inexperienced surgeons and trainees. Since the wear properties of polyethylene have improved in recent years these studies suggest that a fixed bearing option can be used more safely in many patients.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 414 - 414
1 Sep 2009
Ackroyd C Eldridge J Newman J
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Introduction: The Bristol Knee group has performed over 600 patellofemoral arthroplasties in the last 18 years. Experience with the Lubinus prosthesis led to the development of the Avon Prosthesis. In the last 11 years we have prospectively recorded the results of over 470 consecutive Avon arthroplasties. The main cause of the 9.5% failure is arthritic disease progression in the tibiofemoral compartments.

Patients and Method: Over the last 11 years we have identified 21 patients from our own series and from tertiary referrals that have persistent pain, which was mainly due to technical error rather than arthritic disease progression. The causes can be classified into three main reasons: First, an incorrect anterior cut in the saggital plane which was cut in either too much flexion or extension. Second, the anterior cut had inadequate external rotation, which should be 3–6 degrees to lateralise the groove and facilitate correct tracking. Third, the prosthesis was oversized in several cases leading to retinacular impingement.

Results: The overall results followed up to 10 years showed excellent and consistent improvement in both pain and function as judged by the WOMAC 12 scale. Of those patients with persistent pain, seven had the femoral component revised to either resize the prosthesis or revise the alignment of the anterior resection and correctly inset the prosthesis, with good results. Ten cases were revised to a total knee replacement. In the remaining cases, two had an Insall realignment, one a patella distalisation, and in one no treatment was required. As a permanent solution new instruments were designed to reduce the incision size and increase the accuracy of the saggial alignment and to create an exact amount of external rotation.

Conclusion: The lessons from 11 years experience with the Avon arthroplasty has led to the development of improved instrumentation which should reduce the failures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 416 - 417
1 Sep 2009
Walton M Newman J
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Objectives: This study aims to assess the psychological profile of patients prior to total knee replacement, medial unicompartmental knee replacement and patellofemoral joint replacement and determine its effect on outcome.

Methods: 113 patients were identified (41 TKR, 37 UKR and 35 PFJR). All patients had mental health assessed preoperatively using SF-12. From the 12 questions a mental and a physical summary score can be calculated (MCS and PCS). The reduced WOMAC score was used pre-operatively to assess knee function and symptoms and then recorded at 8 and 24 months post-operation to assess outcome.

Results: 54% of the patients had pre-operative psychological distress. There was no statistically significant difference demonstrated between them mean MCS scores between the three operation groups. Pre-operative MCS had a significant effect such that increasing psychological distress lead to a worse twenty-four month outcome (p = 0.016). The effect of MCS is most marked in postoperative pain levels (p = 0.008) compared to function (p = 0.016). The mean 24-month rWOMAC in the severely distressed group (MCS< 40) was 28.4 compared to 17.4 in the psychologically well group (MCS> 60).

Conclusions: Pre-operative mental function prior to knee arthroplasty may provide useful information to guide patients as to their expected outcome in the consent process. Those patients with a very high mental component may be counseled to that although their distress is likely to improve with surgery, their eventual outcome may be worse. The effect of MCS may however only be clinically relevant in those patients with severe mental symptoms.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 426 - 426
1 Sep 2009
Reilly KA Barker KL Shamley D Newman M
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This observational study was undertaken to explore the relationship of the foot posture of patients with Medial Compartment Osteoarthritis of the knee (MCOA), patients with hip osteoarthritis (OA) and a healthy control group, using the Foot Posture Index (FPI). Goniometric measurement of talocrural dorsiflexion was also included.

The relationship of foot posture to MCOA and hip osteoarthritis OA has not been explored although in other medical fields, such as neurology and sports medicine, the relationship between foot posture, lower limb pain and function has been acknowledged. In view of the current high incidence of lower limb OA, any investigation of associations that may lead to improved assessment and conservative management is worthy of consideration.

Currently, systematic examination of the foot is not undertaken in routine clinical assessment of patients with lower limb OA and, if this were to be introduced, there would be difficulty in selecting suitable clinical outcome measures. The recent development of the Foot Posture Index (FPI) has addressed the need for a diagnostic clinical tool that measures foot posture in multiple planes and anatomical segments

Sixty participants took part: twenty patients with radiographic and clinical evidence of MCOA grade IV, twenty patients with radiographic and clinical evidence of stage IV OA hip, and twenty age-matched healthy volunteers as a control group.

A one way Analysis of variance (ANOVA) was performed to investigate any differences between the 3 groups for foot posture using FPI scores and talocrural dorsiflexion measurements. This showed that there were significant differences between the groups (p< 0.001). Patients with MCOA had a high positive FPI score (indicating a pronated foot), patients with hip OA had a low negative FPI score (indicating a supinated foot). The healthy controls had a normal score distributed over a wider range than the other two groups. In addition, the results of the Pearsons test indicate that the FPI correlated positively with talocrural dorsiflexion (r = 0.55, p< .001).

Differences in foot characteristics may be influenced by specific treatment modalities such as gait reducation, orthotic provision, specific lower limb strengthening and stretching exercises. Foot assessment might therefore be a useful adjunct to conservative management of both MCOA and hip osteoarthritis.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 48 - 48
1 Mar 2009
Bray R Steele R Newman J Hutabarat S Ackroyd C
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Purpose of Study: Fixed bearing unicompartmental knee replacement (UKR) has become popular since several series have now shown good 10 year survivorship and excellent function. However little is known about survival during the second decade.

Method: From the Bristol database of over 4000 knee replacements 203 St. Georg Sled UKR’s which had already survived 10 years were identified. The mean age at surgery was 67 years (48–85), with 64% being female. This cohort has been further reviewed at an average of 14.8 years (10–30) from surgery to determine survivorship and function.

Results: Survivorship during the second decade was 87.5%. 58 patients (69 knees) had died with implant in situ and only 2 after revision. A further 15 UKR’s have been revised at an average of 13 years post op; 7 for progression of disease in the opposite compartment, 4 for tibial loosening, 3 for polyethylene wear, 2 for femoral component fracture and 2 for infection.

99 knees were followed for 15 years, 21 knees for 20 years and four for 25 or more years. The average Bristol knee score of the surviving knees fell from 86 to 79 during the second decade, largely as a result of aging.

A previous study of the St Georg. Fixed bearing UKR showed an 89% 10 year survivorship and this is now extended to 82% at 15 years and 76.5% at 20 years.

Conclusion: Satisfactory survival of fixed bearing UKR can be achieved in the second decade suggesting that the indications for mobile bearings require careful definition since there is a higher incidence of complications in many people’s hands.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 72 - 72
1 Mar 2009
HASSABALLA M PORTEOUS A Newman JH
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Introduction: There is an impression among Orthopaedic surgeons that mobile bearing knee replacement has a better functional outcome than fixed bearing knee replacement. Since kneeling demands a high level of function after knee replacement this study was undertaken to see if mobile bearings in either total or unicompartmental replacement conferred an advantage.

Methods: A prospective randomised study of 207 TKR patients receiving the same prosthesis (Rotaglid, Corin, UK) was performed. Patients were randomised into a mobile bearing group (102 patients with a mean age of 53 years) and a fixed bearing group (105 patients with a mean age of 55 years). Data was also prospectively collected on 215 UKR patients who received the same unicompartmental implant (AMC, Uniglide, Corin, UK). 136 patients (Mean age: 62 yrs) had a mobile insert and 79 (mean age: 65 yrs) a fixed insert.

All patients completed the Oxford Knee Questionnaire preoperatively as well as at 1 and 2 years postoperatively. Their stated kneeling ability and total scores were analysed with a perfect score for kneeling ability being 4, and 48 the maximum total score.

Results: In all groups both the kneeling ability and the total scores improved markedly from their preoperative state. At two years the total score for the fixed bearing devices was marginally better than for the mobile (Rotaglide 36;31 and Uniglide 37;33)

There was a more striking difference with respect to kneeling ability with the fixed bearing variants performing better, (Rotaglide 1.4; 0.9 and Uniglide 1.9; 1.4), However, the greatest difference was between the UKR and TKR groups (UKR 1.7; TKR 1.2). Pre-operatively less than 2% of TKR patients (7% of the UKR patients) could kneel. Post-operatively, the patients’ kneeling ability improved with 21% for the mobile bearing, 32% of fixed bearing UKR patients. The TKR patients kneeling ability was 13% of the mobile, 26% of fixed bearing patients were able to kneel with little or no difficulty. In all groups the stated kneeling ability was poor with less than 50% of any group being able to kneel with ease or only minor difficulty.

Conclusion: Those undergoing UKR appeared to perform better than those with a TKR. None of the forms of knee replacement used resulted in good kneeling ability, though this function was improved by arthroplasty in all groups. Mobile bearing inserts


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 34 - 34
1 Mar 2009
Clare T Newman J Ackroyd C Evans R
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Since 1996 over 400 isolated patellofemoral replacements using the Avon prosthesis have been undertaken in Bristol. As a result of the usually gratifying outcomes seen in patients over 55 years old, the indications for this surgery were soon extended to include the many younger patients who have severely disabling patellofemoral disease. We present results from a prospective cohort study of patients under 55 years of age at the time of surgery.

110 knees in 86 patients (median age 47 years, range 24–54) have been treated with Avon patellofemoral replacement (88 in females and 22 in males). Diagnoses included lateral facet OA (59 knees), patella dislocation (25 knees), trochlear dysplasia (41 knees) and post patellectomy instability (7 knees). 79 knees had undergone previous surgery. 17 knees required additional intra-operative procedures including 11 lateral releases and 2 patella realignments. All patients were assessed pre-operatively and at regular intervals using the Oxford, Bristol and WOMAC scores.

All knees were scored preoperative and only one knee has been lost to follow-up due to the patient’s death, which was unrelated to surgery. Post-operative Oxford knee scores have been obtained for 106 knees with follow-up between 8 months and 8 years (mean follow-up 24 months). The mean Oxford score improved from 18 preoperatively to 31 at latest review. Bristol and WOMAC scores showed similar improvements. 16 knees required post-operative additional procedures including 6 lateral releases, 3 patella realignments and 11 revisions. Of the revisions 5 were for progression of tibiofemoral OA but none of these were knees with trochlear dysplasia. Equally good mean scores were seen when comparing patients with the 3 main underlying pathologies (trochlear dysplasia, patellar dislocation and lateral facet OA). At least 37% of the patients studied had pre-existing trochlear dysplasia and the majority of these patients report onset of symptoms, often patellar dislocation, in the first three decades of life. More than 90% of patients were overweight or obese according to their BMI at the time of surgery.

Many of this type of patient, with disabling symptoms, wish to “live now”. The short-term improvements are frequently dramatic. As yet there is no suggestion of prosthetic failure. Revision presents little difficulty since minimal bone is resected in the primary proceedure. Radiological deterioration of the tibio femoral joint is seen in some cases of primary OA but not with trochlear dysplasia.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 1 | Pages 52 - 57
1 Jan 2009
Newman J Pydisetty RV Ackroyd C

Between 1989 and 1992 we had 102 knees suitable for unicompartmental knee replacement (UKR). They were randomised to receive either a St Georg Sled UKR or a Kinematic modular total knee replacement (TKR). The early results demonstrated that the UKR group had less complications and more rapid rehabilitation than the TKR group. At five years there were an equal number of failures in the two groups but the UKR group had more excellent results and a greater range of movement.

The cases were reviewed by a research nurse at 8, 10 and 12 years after operation. We report the outcome at 15 years follow-up. A total of 43 patients (45 knees) died with their prosthetic knees intact. Throughout the review period the Bristol knee scores of the UKR group have been better and at 15 years 15 (71.4%) of the surviving UKRs and 10 (52.6%) of the surviving TKRs had achieved an excellent score. The 15 years survivorship rate based on revision or failure for any reason was 24 (89.8%) for UKR and 19 (78.7%) for TKR. During the 15 years of the review four UKRs and six TKRs failed.

The better early results with UKR are maintained at 15 years with no greater failure rate. The median Bristol knee score of the UKR group was 91.1 at five years and 92 at 15 years, suggesting little functional deterioration in either the prosthesis or the remainder of the joint. These results justify the increased use of UKR.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 575 - 575
1 Aug 2008
Porteous AJ Mulford JS Newman JH Ackroyd CE
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Purpose: Revision patellofemoral arthroplasty (PFA) is a relatively uncommon procedure, with no published reviews identified in the literature. Revision PFAs performed at our institution were reviewed to determine the reasons for PFA failure, the technical ease of revision and to document patient-reported outcomes after revision.

Methods: A prospective review of a cohort of 411 Avon PFA patients identified 31 subsequent revision knee procedures in 27 patients. Data was collected from the institution’s prospective data base, operative reports, X-rays and medical records. Post-operative knee scores (Oxford Knee Score, WOMAC Osteoarthritis Index, Bristol Knee Score) were available on 26 knees.

Results: The commonest reason for revision was progression of osteoarthritis (18 cases) followed by undetermined pain (7 cases). Patients with undetermined pain were found to be revised sooner than patients with disease progression (33 months vs 63 months) and also reported poorer outcome scores at 2 years post revision than the disease progression group.

Only two trochlea components were loose at the time of revision and one patella had a large amount of macroscopic wear. All other components were found to be well fixed with minimal wear at the time of revision. There were no difficulties in removing either component. No cases required augments or stemmed femoral components due to bone loss.

Patients undergoing revision surgery did report improvement in their post revision outcome scores compared with their pre-operative scores. The average Oxford Knee Score improved from 17 to 23, Bristol Knee Pain Scores improved from 11 to 20 and Bristol Knee Functional Scores improved from 15 to 16. These results are poorer than those recorded by the overall cohort of primary PFA.

Conclusion: PFA is easy to revise to a primary total knee. Results of revision knees are improved from pre-operative scores but not as good as expected.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 531 - 532
1 Aug 2008
Barker KL Newman MA Pandit H Murray DW
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Introduction: Metal-on-metal hip resurfacing arthroplasty (HRA) is currently recommended for younger, active patients with high expectations but information about outcomes is limited. Reports concentrate on wear, fracture rates and radiographic appearance, rather than function. Studies that report function do not describe rehabilitation protocols. This data is important to discussions about likely outcomes and restrictions prior to consent and to fully evaluate HRA.

Methods: Consecutive Conserve HRA operations were reviewed 1 year post-surgery. Function was assessed using 3 validated questionnaires; the OHS (Oxford Hip Score), HOOS (Hip Disability and Osteoarthritis Outcome Score) and UCLA Activity Scale. Complications, pain, ROM, muscle strength, single leg stand, walking and stair climbing ability were recorded.

Results: 125 HRA were reviewed (68 right, 57 left hips) in 120 patients (71 male, 49 female) of mean age 56 years. 86.7% recorded no complications, but 20% had pain at 3 months. The median OHS was 15, median UCLA 7 (active) and mean HOOS 82.78%. Operated hip flexors, extensors and abductors were weaker (p=0.000) and hip flexion ROM a mean 94.46 ± 12.71 (55–120) degrees. For 25% walking was limited, 7.6% needed a stick and 10% a stair rail. The OHS correlated with HOOS pain subscale (r=0.812, p=0.000), flexion ROM (r=0.426, p=0.000), hip extensor (r=0.359, p=0.000) and abductor (r=0.424, p=0.000) strength. Pain at 3 months correlated with the HOOS pain subscale (p=0.000, r= 0.503).

Discussion: Although outcomes were generally good with few complications, high levels of function and activity 25% had poor outcomes; with pain, restricted hip flexion, decreased strength, limited walking and functional problems, particularly putting on socks. Pain present at 3 months was associated with pain and worse function at 1 year. It is postulated this sub-optimal recovery may be related to current rehabilitation protocols adopted from THA and not tailored to HRA.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 579 - 579
1 Aug 2008
Gardner R Newman J
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Background: In the UK 80% unicompartmental knee replacements(UKRs) and 10% of total knee replacements(TKRs) use mobile bearings. It is suggested that mobile bearings are more physiological and wear less, however it is still unclear whether patients tolerate mobile bearing knee replacements as well.

Patients and methods: We report four prospective studies,. Two compared fixed with mobile bearings in TKR and two in UKR. The prostheses involved were fixed and mobile variants of the Rotaglide (TKR), Kinemax (TKR) and Uniglide (UKR). In addition the Oxford and St. George Sled UKRs were compared. All except the Uniglide study were randomized prospective trials (RCTs)

611 patients were involved with a mean age of 68 years. Residual pain following surgery was assessed with either the Oxford Knee Score (OKS) or the WOMAC score. The patients were followed up at one and two years postoperatively by a Research nurse and the findings recorded prospectively on the Bristol Knee database.

Results:

Study 1: Rotaglide. Prospective RCT. 171 patients. Mean pain score (OKS) Fixed bearing 15.4 v Mobile bearing 13.2. P= 0.012. Fixed bearing prosthesis caused significantly less pain.
Study 2: Kinemax. Prospective RCT. 198 patients. Mean pain score (WOMAC) Fixed bearing 8.9 v Mobile bearing 8.3. P = 0.443. Trend favouring fixed bearing.
Study 3: Uniglide Non-randomised trial. 184 patients. Mean pain score (WOMAC) Fixed bearing 7.6 v Mobile bearing 10.1. P < 0.001. Fixed bearing caused significantly less pain.
Study 4: St. George Sled v Oxford. Prospective RCT. 94 patients. Mean pain score (OKS) 15.8 v 13.9 . P= 0.058. Strong trend suggesting the Sled caused less pain.

Conclusion: Our data suggests that the fixed bearing knee replacements result in less residual pain than their mobile bearing counterparts, at least in the first two years following surgery.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 526 - 526
1 Aug 2008
Lakkireddi MP Gill MI Chan MJ Kotrba DM Newman-Saunders DT Marsh MG
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Background: The major problem achieving lumbar spinal fusion is developing pseudarthrosis. At present the gold standard in achieving fusion is the use of autograft from pelvis or posterior elements of the spine. However the potential limitations of insuffient quantity and donor site morbidity have led to search for bone graft alternatives like DBM which contains osteinductive BMPs.

Aims & Methods: A Prospective Randomized Control trial comparing the effectiveness of demineralised Bone Matrix (DBM Putty)/autograft composite with autograft in lumbar spinal fusion.

35 patients were included in the trial; they were randomized to have DBM and autograft on one side, and autograft alone on other side to side. Patients were followed up with interval radiographs for total of 24mons. To date 20 patients have completed minimum 12mons follow up. The mineralization of fusion mass lateral to the instrumentation on each side was graded Absent, Mild (< 50%), Moderate (> 50%) or Complete fusion (100%). The assessment was made by two orthopaedic consultants and a musculoskeletal radiologist who were blinded to graft assignment.

Results: The sex distribution was 11:9 male to females with a mean age of 55.2 (21–87 years) and an average follow up of 18mons (12–24mons). Nine patients had single level fusion and the remainder had more than one level fusion. At 12 months on the side of DBM, 15% (6 of 20) had complete fusion, 80% (16 of 20) had moderate fusion, and 5% had no fusion mass. During the same period on the other side, 25% did not show any sign of fusion. There was no correlation with number of levels, age or sex.

Conclusions: Osteoinductive properties of DBM would appear to help in achieving early and higher union rates in lumbar spinal fusion. DBM reduces the amount of harvested autograft graft and also minimises the morbidity of donor site complications.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 574 - 574
1 Aug 2008
Barton T White S Porteous A Mintowt-Czyz W Newman J
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Purpose: To review long-term outcome following knee arthrodesis, and compare this with patient outcome following revision knee arthroplasty.

Methods: Case notes and radiographs of patients who underwent arthrodesis using the Mayday nail were reviewed retrospectively for evidence of clinical and radiological union. Patients also completed an SF12 health survey and Oxford knee score in the form of postal questionnaires. Each patient was matched with patients who had undergone revision knee arthoplasty and the outcomes were compared.

Results: 19 patients were reviewed who underwent knee arthrodesis using a Mayday nail in two centres between 1993 and 2004. 18 cases had united clinically and radiologically with one case lost to follow-up. Mean SF12 scores of patients following knee arthrodesis indicated severe physical (28.8) but only mild mental (43.3) disabilities. The mean Oxford knee score in this group was 41.0. These results were comparable with matched patients following revision knee arthroplasty who scores 27.2 (physical) and 41.1 (mental) on the SF12, and a mean of 38.8 on the Oxford knee score.

Conclusion: Outcome scores following knee arthrodesis were similar to those following revision knee arthroplasty making it an option worth considering in selected patients requiring revision surgery.

Discussion: The Mayday nail provides a method of knee arthrodesis with a high union rate and an acceptable complication rate. Outcome scores following arthrod-esis were not dissimilar to those following revision total knee replacement. These results suggest that knee arthrodesis may be considered as an acceptable alternative to complex knee revision surgery.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 581 - 581
1 Aug 2008
Arastu M Vijayaraghavan J Robinson J Chissell H Hull J Newman J
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Background: We have noted a concerning number of early failures (as defined by revision) for Preservation medial mobile-bearing uni-compartmental knee replacements (UKR’s) implanted in our hospital. This study retrospectively reviewed the postoperative radiographs to see if these were as a result of surgical technical failure.

Methods: Between 2003 and 2004, 43 medial mobile-bearing Preservation UKR’s were implanted into 39 patients. The average age of the patients at the time of the index procedure was 61.4 years (range, 46–85), (20 males). The immediate post-operative radiographs were reviewed by 2 independent orthopaedic consultants and a registrar, who were blinded to the patient outcomes, using the radiographic criteria used for the Oxford UKR. We however, particularly tried to identify any medio-lateral offset between femoral and tibial components due to the constrained nature of the prosthesis. A compound error score for all other technical errors was also calculated for each patient.

Results: Six (13.9%) of 43 knees were revised (5 for persistent pain, 1 for tibial component subsidence). Technical errors were few and no correlation was found between post-operative radiographic appearances and the subsequent need for revision. The mean compound error score (maximum value 18) was 4.5 (range, 2–9) in the revision cases and in the non revised cases 3.2 (range, 0–8).

Conclusions: We believe this study gives credence to the opinion that the DePuy Preservation mobile-bearing implant has design faults and is over-constrained leading to early failures in some cases.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 580 - 580
1 Aug 2008
Hassaballa M Porteous A Newman JH
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Introduction: There is an impression among Orthopaedic surgeons that mobile bearing knee replacement has a better functional outcome than fixed bearing knee replacement. Since kneeling demands a high level of function after knee replacement this study was undertaken to see if mobile bearings in either total or unicompartmental replacement conferred an advantage.

Methods: A prospective randomised study of 207 TKR patients receiving the same prosthesis (Rotaglid , Corin, UK) was performed. Patients were randomised into a mobile bearing group (102 patients with a mean age of 53 years) and a fixed bearing group (105 patients with a mean age of 55 years).

Data was also prospectively collected on 215 UKR patients who received the same Unicompartmental implant (AMC, Uniglide, Corin, UK). One hundred and thirty six patients (Mean age: 62 yrs) had a mobile insert and 79 (mean age: 65 yrs) a fixed insert.

All patients completed the Oxford Knee Questionnaire preoperatively as well as at 1 and 2 years postoperatively. Their stated kneeling ability and total scores were analysed with a perfect score for kneeling ability being 4 and 48 the maximum total score.

Results: In all groups both the kneeling ability and the total scores improved markedly from their preoperative state. At two years the total score for the fixed bearing devices was marginally better than for the mobile (Rotaglide 36;31 and Uniglide 37;33)

There was a more striking difference with respect to kneeling ability with the fixed- bearing variants performing better, (Rotaglide 1.4; 0.9 and Uniglide 1.9; 1.4), However, the greatest difference was between the UKR and TKR groups (UKR 1.7; TKR 1.2). Pre-operatively less than 2% of TKR patients (7% of the UKR patients) could kneel. Post-operatively, the patients’ kneeling ability improved with 21% for the mobile bearing, 32% of fixed bearing UKR patients.

The TKR patients kneeling ability was 13% of the mobile, 26% of fixed bearing patients were able to kneel with little or no difficulty. In all groups the stated kneeling ability was poor with less than 50% of any group being able to kneel with ease or only minor difficulty.

Conclusion: Those undergoing UKR appeared to perform better than those with a TKR. None of the forms of knee replacement used resulted in good kneeling ability, though this function was improved by arthroplasty in all groups. Mobile bearing inserts did not confer any advantage with respect to kneeling and in fact performed worse with regard to this particular knee function.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 324 - 325
1 Jul 2008
Ackroyd CE Newman JH Evans R Joslin CC
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Objective: To review the results of the Avon patellofemoral arthroplasty at 5 to 8 years.

Methods: The Avon patellofemoral arthroplasty was introduced in clinical practice in September 1996. We present a prospective cohort review of all patients treated in the first three years. Patients were evaluated using the Bristol knee score (BSK), the Melbourne patella score (MPS) and the Oxford knee score (OKS).

Results: 109 patellofemoral arthroplasties were performed in 92 patients between September 1996 and November 1999. The median age was 68 years (range 46 to 86 years). Nine patients (12 knees) died and two patients (two knees) were unfit for follow-up. Ten knees in 9 patients were lost to follow-up giving a follow-up rate of 89%. The mean period of follow-up was 5.6 years.

The median pain score rose from 15/40 pre-operatively to 40 points at eight years. The median (MPS) rose from 10/30 points pre-operatively to 25 points at eight years. The median (OKS) rose from 18/48 pre-operatively to 38 at eight years. 87% of knees had mild or no pain at eight years. There were no cases of failure of the prosthesis itself. All 15 revisions resulted from progression of arthrititis in the tibio-femoral joint. The five-year survival rate for all causes with 86 cases at risk was 96%.

Conclusions: The results show that this type of arthroplasty can give predictable pain relief and excellent functional improvement in patients with isolated patello-femoral arthritis. Disease progression is the main reason for revision to total knee replacement and great care is required in assessing the indications for this procedure.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Kulkarni MM Eldridge JD Newman JH
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Introduction: Anterior Knee pain is a very common presentation in Orthopaedic out patient clinics. However, Trochlear Dysplasia as a condition is still not very well understood.

Materials and Methods: Operative findings in patients undergoing Trochleaplasty and in young patients undergoing Patella-femoral arthroplasty were studied. Patients having trochlear dysplasia were identified. All these patients were sent a questionnaire to explore the variety of symptoms they experienced. 87 patients were identified for the study. 71(82%) patients responded to the questionnaire.

Results: Two subgroups were identified, one with dislocation of patella and the other without dislocation of the patella. Patients in patella dislocation group were younger (12 years vs 24) than those who presented without dislocation of patella. Patella dislocation group had more patients with anterior knee pain (71% vs 52%) as teenagers as compared to the group without dislocations. Symptoms such as giving way, lack of trust and unable to participate in sports were more commonly seen in the group with patella dislocation whereas, limited walking distance and difficulty with climbing the stairs were more commonly seen in the group without dislocation. Symptoms such as pain, catching and locking were seen equally amongst the two groups.

Conclusion: We believe that the patients with trochlear dysplasia have a bimodal presentation. Patients with dislocation of patella present earlier than those without patella dislocation. These two groups also have different symptoms at presentation. It is important to identify these subgroups correctly for appropriate management.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 324 - 324
1 Jul 2008
Steele RG Newman JH Hutabarat S Evans R Ackroyd CE
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Purpose of Study: Fixed bearing unicompartmental knee replacement (UKR) has become popular since several series have shown good 10 year survivorship and excellent function. However little is known about survival during the second decade.

Method: From the Bristol database of over 4000 knee replacements 203 St. George Sled UKR’s which had already survived 10 years were identified. The mean age at surgery was 67 years (48–85), with 64% being female. This cohort has been further reviewed at an average of 14.8 years (10–30) from surgery to determine survivor-ship and function.

Results: Survivorship during the second decade was 87.5%. 58 patients (69 knees) had deceased with implant in situ, only 2 after revision. A further 15 UKR’s have been revised at an average of 13 years post op; 7 for progression of disease, 4 for tibial loosening, 3 for polyethylene wear, 2 for femoral component fracture and 2 for infection.

99 knees were followed for 15 years and 21 knees for 20 years. The average Bristol knee score of the surviving knees fell from 86 to 79 during the second decade.

A previous study showed an 89% 10 year survivor-ship and this is now extended to 82% at 15 years and 76.5% at 20 years.

Conclusion: Satisfactory survival of fixed bearing UKR can be achieved in the second decade suggesting that the indications for mobile bearings require careful definition since there is a higher incidence of complications in many people’s hands.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 329 - 329
1 Jul 2008
Davis CR Newman JH Davies AP
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The purpose of this study was to determine the incidence of revision total knee replacement (TKR) within 5 years of the index procedure at a large multi-surgeon unit using a single prosthesis and to determine the cause of failure of those implants.

This was a retrospective review of all primary Kine-max Plus TKR performed at the Avon Orthopaedic Center between 1.1.1990 and 1.1.2000. Cases were identified that required revision arthroplasty in any form within 5 years of the index procedure. Case notes and Xrays were reviewed to determine causes of failure.

There were 2826 primary Kinemax Plus TKR performed during the study period. Of these 20 were known to have required revision surgery within 5 years. 8 were revised for deep infection of the prosthesis and 12 for aseptic causes. The overall incidence of premature failure of the Kinemax Plus TKR at 5 years was 0.71%. The incidence of aseptic premature failure at 5 years was 0.42%. Detailed examination of the clinical records indicated that some form of technical error at the time of the index arthroplasty was responsible for the early failure of 6 prostheses. This equates to 0.21% of the procedures performed. Aseptic loosening of the remaining 6 cases could not be attributed to a specific cause.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 325 - 325
1 Jul 2008
Clare TD Newman JH
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Introduction: Following previously gratifying results in older patients the study aims to quantify the outcomes and identify any contraindications in patient selection for patello-femoral replacements using the Avon pros-thesis in patients under 55 years old.

Method: We present early outcome results for a prospective cohort study of patients under 55 years of age.110 knees in 86 patients (median age 47years, range 25–54) have been treated with Avon patello-femoral replacement (88 in females and 22 in males). Diagnoses included lateral facet OA (59 knees), patella dislocation (36 knees), trochlear dysplasia (39 knees) and post patellectomy instability (7 knees). 108 knees had undergone previous surgery. 14 knees required additional intra-operative procedures (including 11 lateral releases and 2 patella realignments). All patients were assessed pre-operatively using the Oxford, Bristol and WOMAC scores.

Results: No knees have been lost to follow-up. 82 knees have post operative scores available (mean follow-up 27 months). 8 have been revised (6 due to progression of OA). The mean Oxford, Bristol and WOMAC scores all improved: 18 to 32, 56 to 83 and 39 to 25 respectively. Asymptomatic deterioration of the tibio femoral joint is seen in some cases of primary OA but not with trochlear dysplasia. 21 knees required post-operative additional procedures including 6 lateral releases, 3 patella realignments and 5 revisions. Equally good results were seen when comparing patients with the 3 main diagnoses. Trochlear dysplasia is strongly predicted by young age at onset of symptoms and patellar dislocation.

Conclusion: Many of this type of patient, with disabling symptoms, wish to “live now”. The short-term improvements are frequently dramatic. Comparison of underlying pathologies has not identified groups that are performing less well to suggest restricting current indications. As yet there is no suggestion of prosthetic failure. Revision has presented little difficulty since minimal bone is resected primarily.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 7 | Pages 879 - 884
1 Jul 2008
Porteous AJ Hassaballa MA Newman JH

We identified 148 patients who had undergone a revision total knee replacement using a single implant system between 1990 and 2000. Of these 18 patients had died, six had developed a peri-prosthetic fracture and ten had incomplete records or radiographs. This left 114 with prospectively-collected radiographs and Bristol knee scores available for study. The height of the joint line before and after revision total knee replacement was measured and classified as either restored to within 5 mm of the pre-operative height or elevated if it was positioned more than 5 mm above the pre-operative height. The joint line was elevated in 41 knees (36%) and restored in 73 (64%).

Revision surgery significantly improved the mean Bristol knee score from 41.1 (sd 15.9) pre-operatively to 80.5 (sd 15) post-operatively (p < 0.001). At one year post-operatively both the total Bristol knee score and its functional component were significantly better in the restored group than in the elevated group (p < 0.01). Overall, revision from a unicondylar knee replacement required less use of bone graft, fewer component augments, restored the joint line more often and gave a significantly better total Bristol knee score (p < 0.02) and functional score (p < 0.01) than revision from total knee replacement.

Our findings show that restoration of the joint line at revision total knee replacement gives a significantly better result than leaving it unrestored by more than 5 mm. We recommend the greater use of distal femoral augments to help to achieve this goal.