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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_5 | Pages 57 - 57
1 Apr 2019
Borton Z Nicholls A Mumith A Pearce A Briant-Evans T Stranks G Britton J Griffiths J
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Aims

Metal-on-metal total hip replacements (MoM THRs) are frequently revised. However, there is a paucity of data on clinical outcomes following revision surgery in this cohort. We report on outcomes from the largest consecutive series of revisions from MoM THRs and consider pre-revision factors which were prognostic for functional outcome.

Materials and Methods

A single-centre consecutive series of revisions from MoM THRs performed during 2006–2015 was identified through a prospectively maintained, purpose-built joint registry. The cohort was subsequently divided by the presence or absence of symptoms prior to revision. The primary outcome was functional outcome (Oxford Hip Score (OHS)). Secondary outcomes were complication data, pre- and post-revision serum metal ions and modified Oxford classification of pre-revision magnetic resonance imaging (MRI). In addition, the study data along with demographic data was interrogated for prognostic factors informing on post-revision functional outcome.


The Bone & Joint Journal
Vol. 98-B, Issue 10_Supple_B | Pages 22 - 27
1 Oct 2016
Bottomley N Jones LD Rout R Alvand A Rombach I Evans T Jackson WFM Beard DJ Price AJ

Aims

The aim of this to study was to compare the previously unreported long-term survival outcome of the Oxford medial unicompartmental knee arthroplasty (UKA) performed by trainee surgeons and consultants.

Patients and Methods

We therefore identified a previously unreported cohort of 1084 knees in 947 patients who had a UKA inserted for anteromedial knee arthritis by consultants and surgeons in training, at a tertiary arthroplasty centre and performed survival analysis on the group with revision as the endpoint.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_12 | Pages 21 - 21
1 Nov 2015
Barbur S Gallespie-Gallery H Chapman P Griffiths H Conn K Britton J Briant-Evans T
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Introduction

The prevalence of adverse reactions to metal debris (ARMD) associated with metal on metal (MoM) hip arthroplasty has been reported to be as high as 69%. Such findings promoted the development of metal-artefact reducing sequence (MARS)-magnetic resonance imaging (MRI) classifications, with the aim of stratifying soft lesions by severity of disease. The Modified Oxford Classification is a straightforward system that has been shown to correlate with disease progression.

Methods

The aim of this study was to test the reliability of this classification between observers. Seven observers were recruited, all with a musculoskeletal background. Using the PACS image analysis system, 20 MARS-MRI scans were provided for interpretation. Observers reviewed these scans in random order at two separate intervals over the course of five weeks. They classified them according to the Modified Oxford Classification as: ‘normal’, ‘trochanteric fluid, ‘effusion’, ‘ARMD type 1’, ‘ARMD type 2’ and ‘ARMD type 3’.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_12 | Pages 22 - 22
1 Nov 2015
Eyre-Brook A Pearce A Lyle N Stranks G Briant-Evans T
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Introduction

The prevalence of adverse reactions to metal debris around metal-on-metal (MOM) hip replacements has been reported to range from 7 to 69%. Little has been published on MRI scans with conventional total hip bearing surfaces. This study aimed to establish the prevalence of soft tissue lesions associated with metal-on-polyethylene (MOP) and ceramic-on-ceramic (COC) bearings, compared to MOM prostheses.

Patients/Materials & Methods

All Metal Artefact Reduction Sequence (MARS) MRI scans for MOM THRs performed at our unit from January 2009 to present were reviewed, identifying those with contralateral primary MOP or COC THRs included on the scan. These were compared to a previously analysed cohort of 281 MOM THRs. Scans were classified using the Modified Oxford Classification as ‘Normal’, ‘Trochanteric Fluid’, ‘Effusions’ or Adverse Reactions to Debris.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 75 - 75
1 Jan 2013
Briant-Evans T Yeung H MacDonald A Farrington W
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Critics of Unicompartmental knee replacement (UKR) highlight poor survivorship in national joint registries and argue that revision to Total Knee Replacement (TKR) is technically difficult with inferior function and survivorship compared to primary TKR.

We prospectively reviewed outcomes of UKRs in our institution undergoing early revision to a TKR, comparing conventional revisions to those performed using computer navigation. 20 cases were identified, 7 conventional and 13 navigated. 13 were male and 7 female, mean age at primary UKR was 63.6 years (range: 47–81).

Mean follow up time after revision was 5.2 years (2–9.5). Mean surgical time was 152 mins in conventional revisions and 163 mins for navigated. 43% of conventional cases required revision stems or augments, compared to 15% of conventional cases. Mean Oxford Knee Scores for revised knees were 32.8 in the conventional group and 34.64 in the navigated group, compared to 30.02 in the national joint registry. This compares to a mean Oxford score of 37.16 for primary TKRs in the registry. One of the conventional revisions required a further revision of the tibial component for loosening. This equates to a 95% suvivorship at mean 5 year follow up, or 1.10 revisions per 100 component years. Joint registry data had 1.97 revisions per 100 component years for UKR to TKR revisions, and 0.48 for primary TKRs.

Our results are significantly improved compared to other published series of UKR revisions to TKRs. Only one other series has reported outcomes of these revisions using navigation. Despite small numbers, our results suggest that navigation makes revisions of UKRs more straightforward with similar surgical times. Fewer revision components were required with navigation and functional scores were marginally improved.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 156 - 156
1 Jan 2013
Briant-Evans T Hobby J Stranks G Rossiter N
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The Fixion expandable nailing system provides an intramedullary fracture fixation solution without the need for locking screws. Proponents of this system have demonstrated shorter surgery times with rapid fracture healing, but several centres have reported suboptimal results with loss of fixation. This is the largest comparative series to be reported to date.

We compared outcomes between 50 consecutive diaphyseal tibial fractures treated with a Fixion device at our institution to an age, sex and fracture configuration matched series of 57 fractures at a neighbouring hospital treated with a conventional interlocked intramedullary nail. Minimum follow up time was 2 years.

Operating time was significantly reduced in the Fixion group (mean 61 minutes, range 20–99) compared to the interlocked group (88 minutes, 52–93), p< 0.00001. The union rate was no different between the Fixion group (93.9%) and the interlocked group (96.5%), p=0.527. Time to clinical and radiological union was significantly faster in the Fixion group (median 85 days, range 42–243) compared to the interlocked group (119, 70–362), p< 0.0001. The overall reoperation rate was lower in the Fixion series (24.5% vs 38.6%, p=0.121), although the majority of reoperations in the interlocked group were more minor, for screw removal. 3 Fixion nails were revised for fixation failure and 2 manipulations were required for rotational deformities after falls; all of these patients were non-compliant with post-operative instructions. There were no fixation failures in the interlocked group. 3 fractures were noted to propagate during inflation of Fixion nails.

The Fixion nail is faster to implant and allows more physiological loading of the fracture, with a faster union time. However, these advantages are offset by a reduction in construct stability. Our results have demonstrated a learning curve with a reduction in complications as our indications were narrowed, avoiding osteoporotic, multifragmentary, unstable fractures and non-compliant patients


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 210 - 210
1 Jan 2013
Price M Bailey L Bryant-Evans T Stranks G Britton J
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Aims

Several national studies have shown that the rates of joint replacement are rising and this increase may be greater than that expected by population ageing. The aim of this study was to assess local rates of joint replacement at a district general hospital (DGH) and to investigate whether there had been a change in pre-operative functional status of patients over the study period to account for any change in rates of arthroplasty.

Methods

This was a DGH based local joint registry programme with independent functional assessment and follow up. All patients undergoing primary total hip replacement (THR) and total knee replacement(TKR) between 1 January 2000 and 31 December 2009 were eligible. Only after being listed for surgery were patients assessed with WOMAC and Oxford Hip or Oxford Knee scores. Catchment population data was obtained from the Office of National Statistics


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 354 - 354
1 Jul 2011
Briant-Evans T Veeramootoo D Tsiridis E Hubble M
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Periprosthetic fractures around a cemented femoral stem present a challenge to the treating surgeon. We propose a technique whereby a well fixed cement mantle can be retained in cases with simple fractures that can be reduced anatomically. This technique is well established in femoral stem revision, but not in association with a fracture.

24 Vancouver type B periprosthetic femoral fractures were treated by reducing the fracture and cementing a revision stem into the pre-existing cement mantle, with or without supplementary fixation.

3 patients died in the first 6 months for reasons not related to surgery and one was too frail to attend follow up. The remaining 20 cases were followed up for a mean of 3.0 years. The median time to radiological and clinical union was 3.0 months (2–11). The median Modified Harris Hip Score was 76.9 (35–97) and there was no sign of loosening or subsidence of the revision stems within the old cement mantle in any case at most recent follow up. One patient had further surgery for a delayed union and there were 2 subsequent fractures distal to the original fracture site in patients with poor bone stock.

Our results support the use of the cement-in-cement stem revision technique in anatomically reducible peri-prosthetic fractures with a well preserved pre-existing cement mantle. It is particularly suitable for older patients.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 122 - 123
1 May 2011
Grice J Briant-evans T Dala-ali B Haleem S Hodkinson S Jowett A
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Introduction: Ankle diastasis injury occurs in up to 20% of ankle fractures. Various techniques have been used to treat syndesmosis injuries, but controversy remains and outcome is variable. In light of some recent cases of substandard syndesmosis fixations requiring revision, an audit of our results was undertaken.

Method: Study type: Retrospective audit of radiographs and patient records

Data collection: patients were selected using an orthopaedic database search for operations coded as distal tib/fib ORIF or ankle ORIF.

Study period: 12 months, July 2008 to July 2009 (currently data has been analyzed on the first 6 months only, the remaining 6 months will follow)

Audit questions to be answered: How is ankle diastasis injury being managed? Are we reducing syndesmosis correctly? Should there be a revision to local policy?

Audit standard: Syndesmoses should be adequately reduced and fixation techniques employed should be in accordance with recommendations in standard Orthopaedic reference texts (Rockwood & Green, AO fixation manual 3)

Results: 76 ankle ORIFs in July to December 2008 inclusive. Out of these, 16 had diastasis fixation (21%). 2 of the patients had a syndesmosis width over 6 mm indicating an inadequate reduction of the syndesmosis 1. Both of these required revision surgery. In total 70% of the post operative x-rays showed inadequate syndesmosis fixation or reduction.

Discussion: The single most predictive indicator of a favourable function is accurate reduction of the syndesmosis 2. Substandard fixations are associated with poor long term outcomes. This raises the potential for litigation and the requirement for education and policy change. We have produced policy guidelines for theatre and circulated the information to all surgeons. A further audit will be carried out to assess the effectiveness of this in 6 months time. (The data will be available from this re-audit for presentation at the conference.)


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 174 - 174
1 Mar 2009
Briant-Evans T Hubble M Tsiridis E
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20 Vancouver type B periprosthetic femoral fractures were treated in our unit by cementing a revision stem into the pre-existing cement mantle following fracture reduction. The technique was used in elderly, multiply co-morbid patients with the intention of reducing operative time and peri-operative complications.

3 patients died in the first 3 months from reasons not related to surgery, with no recorded evidence of fracture healing and were excluded from the study and 1 was too frail to attend follow up. The remaining 16 cases were followed up for a mean of 3 years. The mean time to radiological union was 5 months (range: 2–11) and the mean time to clinical union was 4.9 months (range: 2–17). The mean Modified Harris Hip Score in these patients was 66.5 (range: 35.2–97). One patient had further surgery for a delayed union and there was one failure of fixation. The mean hospital stay was 10.8 days and the mean time to fully weight bear 38.1 days.

This study suggests that there is a valid role for the use of the in-cement revision technique in Vancouver type B periprosthetic femoral fractures in a highly selected group of elderly patients unsuitable for lengthy reconstructive procedure


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 397 - 398
1 Jul 2008
Watts A Teoh K Evans T Beggs I Porter D
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Introduction: Local recurrence of tumour following definitive treatment of bone or soft tissue sarcoma is a predictor of increased morbidity. Early detection of local recurrence may affect outcome. The role of magnetic resonance imaging (MRI) screening following definitive treatment is controversial. This study investigates the experience of one treatment centre with routine surveillance MRI following treatment of sarcoma.

Methods: Patients were identified from the records of the Regional Sarcoma Group. With Local Ethics Committee approval the casenotes, MRI and histology reports for sixty-five patients who had routine surveillance MRI scans following definitive treatment of sarcoma in a single treatment centre were reviewed. The minimum follow up period was 24 months. The primary outcome was the presence of local tumour recurrence and whether this was identified on surveillance or interval scanning.

Results: There were sixty-four patients identified with a bone or soft tissue sarcoma. All had undergone surveillance scanning biannually for the first year then annually. Six patients with Ewing’s sarcoma were excluded because they had not had surgical excision. Fifty-eight patients (59% men) with a bone or soft tissue sarcoma without metastasis between 1996 and 2003 were available for study. The median age at diagnosis was 53 years (range 6–78 years). Eighty three percent had a diagnosis of soft tissue sarcoma. Ten patients had a primary bone tumour. Fourteen patients had local recurrence (24%). Six were identified on surveillance scan, and the remaining eight required interval scans because of clinical suspicion of tumour recurrence. There were no statistical differences in gender, age, or tumour characteristics between those identified on surveillance or interval scans. All those detected on surveillance had intra-lesional or marginal resections.

Conclusions: Surveillance scanning has a role in the early detection of local recurrence of bone and soft tissue sarcoma. Whether this results improvements in prognosis require longer-term follow up studies.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 4 | Pages 484 - 487
1 Apr 2008
Watts AC Teoh K Evans T Beggs I Robb J Porter D

This study reports the experience of one treatment centre with routine surveillance MRI following excision of musculoskeletal sarcoma. The case notes, MRI and histology reports for 57 patients were reviewed. The primary outcome was local tumour recurrence detected on either surveillance MRI in asymptomatic patients, or interval MRI in patients with clinical concern. A total of 47 patients had a diagnosis of soft-tissue sarcoma and ten of a primary bone tumour. A total of 13 patients (22%) had local recurrence. Nine were identified on a surveillance scan, and four by interval scans. The cost of surveillance is estimated to be £4414 per recurrence detected if low-grade tumours with clear resection margins are excluded. Surveillance scanning has a role in the early detection of local recurrence of bone and soft-tissue sarcoma.