Aims

This paper describes the methodology, validation and reliability of a new computer-assisted method which uses models of the patient’s bones and the components to measure their migration and polyethylene wear from radiographs after total hip arthroplasty (THA).

Objectives

Our study aimed to examine not only the incidence but also the impact of noise from two types of total hip replacement articulations: ceramic-on-ceramic and ceramic-on-polyethylene.

Objectives

Our study aimed to examine if a mobile-bearing total knee replacement (TKR) offered an advantage over fixed-bearing designs with respect to rates of secondary resurfacing of the patella in knees in which it was initially left unresurfaced.

Introduction: Hip Simulator studies show that use of highly cross-linked polyethylene in total hip replacement reduces polyethylene (PE) wear by a factor of 85–98%. Early clinical studies using RSA or computer-aided techniques of polyethylene wear measurement show a reduction of 50–80%. There is speculation about why this discrepancy in the clinical and laboratory data should exist. The results of a randomized, prospective double blinded (surgeon and patient) trial (RCT) of cross-linked versus conventional polyethylene, using a 100% reproducible method of PE wear measurement, are reported.

Materials And Methods: After Ethics Committee approval, the two authors enrolled 124 patients onto an RCT comparing Enduron (non cross-linked PE) and highly cross-linked Marathon PE (DePuy, Leeds, UK). Randomization was performed by the circulating nurse intra-operatively opening an envelope which determined whether the patient received an Enduron or Marathon liner appropriate to the size of the metal shell. Liners were implanted into identical metal shells (Duraloc 300) with one screw. They articulated with identical 28mm CoCr femoral heads and cemented Charnley Elite femoral stems. All patients were followed with anteroposterior and lateral radiographs at 3 days, 6 weeks, 3 months 6 months, 1, 2, 3 and 4 years. PE wear was measured with PWAuto, a validated computer-assisted technique with 100% reproducibility and accuracy of ±0.13mm.

Results: One hundred and thirteen patients had appropriate radiographs and follow-up interval. Mean follow-up was 2.6 years (range 2–4 years). Fifty-eight patients received Enduron liners and 55 patients received Marathon liners. At 6 months (E=0.32, M=0.31mm) and one year (E=0.37, M=0.31mm) the three-dimensional PE wear was identical in both groups. Thereafter, all PE wear measurements showed a significant difference in PE wear between the two groups. Wear of the conventional Enduron group continued (0.51mm at 2 years, 0.70 at 3 years, 0.97 at 4 years), while the crosslinked Marathon group showed virtually no further wear (0.32mm at 2 years, 0.32mm at 3 years, 0.33mm at 4 years).

Conclusions: This is the first study to confirm that Hip Simulator predictions of cross-linked PE wear can be reproduced in-vivo. Randomization, double-blinding, and the use of a 100% reproducible technique for wear measurement add further weight to this data.

Aim: To ascertain whether there is a relationship between time to surgery and mortality in hip fracture patients.

Method: The records of 120 patients admitted with hip fractures were examined. The approximate time of injury, the time of admission to hospital, the time of surgery, the number of medical co-morbidities, the A.S.A. grade, age, and length of hospital stay, were recorded. Death statistics were obtained from the Registrar of Births Deaths and Marriages. An analysis was then performed to assess the presence of correlation between time from injury to surgery, time from admission to surgery and three and six-month mortality in patients who were A.S.A. grades two or three.

Results: Preliminary analysis of the data showed a strong correlation between time from injury and the time from admission, to surgery and subsequent death. When these times exceeded 24 hours the mortality increased.

Conclusion: This study suggested that every effort should be made to operate on patients with hip fractures within 24 hours of admission to minimise mortality resulting from this injury.

Aim: To examine the histology of the bone-cement interface in a canine total hip model comparing two different cementing techniques.

Method: Seven adult mongrel dogs underwent staged bilateral total hip replacement. On one side the cement was packed into the femur with a finger while on the opposite side the femoral canal was washed, brushed, distally plugged and injected with cement under pressure before inserting the femoral component. Sequential fluorochrome bone labelling was performed. The dogs were sacrificed up to six months after the surgery. Undecalcified sections of the femur were examined by fluorescent microscopy.

Results: Post-operative radiographs showed complete filling of the proximal femur with cement in the pressure injected group, and a relatively thin mantle in the finger-packed group. Histology of the finger-packed group showed minimal intrusion of cement into the cancellous bed, direct apposition of cement and bone with small areas of fibrous tissue interposition. In the pressure- injected group the cement extended to the endosteal cortex, there was no bone necrosis, and the intruded bone underwent remodelling similar to that at the margins.

Conclusions: This study suggested that ‘third generation’ cementing techniques result in greater contact between bone and cement, and may explain the claim that femoral stems in humans inserted using third generation techniques are more durable than those inserted using ‘first generation’ techniques.