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Bone & Joint Research
Vol. 3, Issue 5 | Pages 139 - 145
1 May 2014
Symmetry analysis of talus bone
Islam K Dobbe A Komeili A Duke K El-Rich M Dhillon S Adeeb S Jomha NM
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Objective

The main object of this study was to use a geometric morphometric approach to quantify the left-right symmetry of talus bones.

Methods

Analysis was carried out using CT scan images of 11 pairs of intact tali. Two important geometric parameters, volume and surface area, were quantified for left and right talus bones. The geometric shape variations between the right and left talus bones were also measured using deviation analysis. Furthermore, location of asymmetry in the geometric shapes were identified.

Results

Numerical results showed that talus bones are bilaterally symmetrical in nature, and the difference between the surface area of the left and right talus bones was less than 7.5%. Similarly, the difference in the volume of both bones was less than 7.5%. Results of the three-dimensional (3D) deviation analyses demonstrated the mean deviation between left and right talus bones were in the range of -0.74 mm to 0.62 mm. It was observed that in eight of 11 subjects, the deviation in symmetry occurred in regions that are clinically less important during talus surgery.

Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 285 - 285
1 May 2009
QUANTITATIVE MEASUREMENT OF THORACIC DISC SIGNAL INTENSITY IN MAGNETIC RESONANCE IMAGING
Niemeläinen R Videman T Dhillon S Battié M
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Purpose and Background: Cerebrospinal fluid (CSF) is used as an intrabody reference for quantitative disc signal intensity measurements in the lumbar spine, but may be less ideal for investigating thoracic disc degeneration. The purpose of this study was to investigate the spinal cord as an alternative intrabody reference for thoracic disc signal intensity measurements.

Methods: T2-weighted MR images from the thoracic spine (T6-T12) were obtained using two 1.5-Tesla scanners from a population-based sample of 523 men (35–70 years). Quantitative data on signal intensities of the disc, CSF and spinal cord were acquired using custom-made software. The signal intensity of the spinal cord was correlated with the signal intensity of the adjacent CSF (criterion reference) in a sample of subjects with visually clean CSF-samples. The measured disc signal intensities were correlated with age in three ways; without adjustment and adjusting for CSF and spinal cord. Pearson’s r was used for the correlations and intraclass correlation coefficient (ICC) to examine the interobserver repeatabilities of spinal cord signal intensity measurements.

Results: Spinal cord signal intensity measurements were repeatable (ICC=0.99–1). Clean CSF-samples correlated highly with the signal intensities of the spinal cord (r=0.91–0.99). The correlations of spinal cord-adjusted disc signal intensity with age (r=−0.30 to −0.40) were somewhat higher than for age and CSF-adjusted disc signal intensity (r=−0.26 to −0.36). In comparison, correlations between unadjusted disc signal intensity and age were low (r=−0.11 to −0.19).

Conclusion: Spinal cord is a good alternative intrabody reference to the current gold standard (CSF) for disc signal intensity measurements in the thoracic spine.