Introduction

The General Social Survey estimates that 19 million Americans shoot firearms, with 10% of this population being over the age of 65. More reverse total shoulder arthroplasty (rTSA) are seeking to return to physical activity after surgery, but the effects of shooting a firearm on the fixation of a rTSA implant are unknown. This study will seek to examine the recoil effect of a firearm on a rTSA baseplate fixation, by recording the forces absorbed by a shooter and applying these forces to a rTSA implant assembly in laboratory conditions.

Introduction

Highly crosslinked ultrahigh-molecular-weight polyethylene (XLPE) reduces wear and osteolysis in total hip arthroplasty, but it is unclear if XLPE will provide the same clinical benefit in total knee arthroplasty (TKA). Adhesive and abrasive wear generally dominate in polyethylene acetabular components, whereas fatigue wear is an important wear mechanism in polyethylene TKA tibial inserts. The wear resistance of XLPE depends on the crosslink density of the material, which may decrease during in vivo mechanical loading, leading to more wear and increased oxidation. To examine this possibility, we measured crosslink density and oxidation levels in loaded and unloaded locations of retrieved tibial inserts to evaluate the short-term performance of XLPE material in TKA.

Background

Though many advantages of reverse total shoulder arthroplasty (RTSA) have been demonstrated, a variety of complications indicate there is much to learn about how RTSA modifies normal shoulder function. This study assesses how RTSA affects deltoid muscle moment arms post-surgery using a subject-specific computational model driven by in vivo kinematic data.

Introduction

Posterior glenoid wear is common with glenohumeral osteoarthritis. To correct posterior wear, surgeons may eccentrically ream the anterior glenoid to restore version. However, eccentric reaming undermines prosthesis support by removing unworn anterior glenoid bone, compromises cement fixation by increasing the likelihood of peg perforation, and medializes the joint line which has implications on joint stability. To conserve bone and preserve the joint line when correcting glenoid version, manufacturers have developed posterior augment glenoids for aTSA and rTSA applications. This clinical study quantifies outcomes achieved using posteriorly augmented aTSA/rTSA glenoid implants in patients with severe posterior glenoid wear at 2 years minimum follow-up.

Introduction

A better understanding of the rate of improvement associated with aTSA and rTSA is critical to establish accurate patient expectations for treatment to reduce pain and restore function; more realistic patient expectations pre-operatively may lead to greater patient satisfaction post-operatively. To this end, this study quantifies the rate of improvement in outcomes of aTSA and rTSA using 5 different scoring metrics for 1641 patients with one platform shoulder arthroplasty system.

Introduction

The clinical impact of scapular notching is controversial. Some reports suggest it has no impact while others have demonstrated it does negatively impact clinical outcomes. The goal of this clinical study is to analyze the pre- and post-operative outcomes of 415 patients who received rTSA with one specific prosthesis (Equinoxe; Exactech, Inc).

Introduction

Due to the predictability of outcomes achieved with reverse shoulder arthroplasty (rTSA), rTSA is increasingly being used in patients where glenoid fixation is compromised due to presence of glenoid wear. There are various methods to achieve glenoid fixation in patients with glenoid wear, including the use of bone grafting behind the glenoid baseplate or the use of augmented glenoid baseplates. This clinical study quantifies clinical outcomes achieved using both techniques in patients with severe glenoid wear at 2 years minimum follow-up.

Introduction

Acetabular component position is considered a major factor affecting the etiology of hip dislocation. The ‘Lewinnek safe zone’ has been the most widely accepted range for component position to avoid hip dislocation, but recent studies suggest that this safe zone is outdated. We used a large prospective institutional registry to ask: 1) is there a ‘safe zone’ for acetabular component position, as measured on an anteroposterior radiograph, within which the risk of hip dislocation is low?, and 2) do other patient and implant factors affect the risk of hip dislocation?

Reverse total shoulder arthroplasty (RTSA) has had rapidly increasingly utilization since its approval for U.S. use in 2004. RTSA accounted for 11% of extremity market procedure growth in 201. Although RTSA is widely used, there remain significant challenges in determining the location and configuration of implants to achieve optimal clinical and functional results. The goal of this study was to measure the 3D position of the shoulder joint center, relative to the center of the native glenoid face, in 16 subjects with RTSA of three different implant designs, and in 12 healthy young shoulders.

CT scans of 12 healthy and 16 pre-operative shoulders were segmented to create 3D models of the scapula and humerus. A standardized bone coordinate system was defined for each bone (Figure 1). For healthy shoulders, the location of the humeral head center was measured relative to the glenoid face center. For the RTSA shoulders, a two-step measurement was required. First, 3D models of the pre-operative bones were reconstructed and oriented in the same manner as for healthy shoulders. Second, 3D model-image registration was used to determine the post-operative implant positioning relative to the bones. The 3D position and orientation of the implants and bones were determined in a sequence of six fluoroscopic images of the arm during abduction, and the mean implant-to-bone relationships were used to determine the surgical positioning of the implants (Figure 2). The RTSA center of rotation was defined as the offset from the center of the implant glenosphere to the center of the native glenoid face.

The center of rotation in RTSA shoulders varied over a much greater range than the native shoulders (Table 1 (Figure 3)). Lateral offset of the joint center in RTSA shoulders was at least 6 mm smaller than the smallest joint center offset in the healthy shoulders. The center of rotation in RTSA shoulders was significantly more inferior than in healthy shoulders. The range of anterior/posterior placement of the rotation center for RTSA shoulders was bounded by the range for normal shoulders.

How to best position RTSA implants for optimal patient outcomes remains a topic of great debate and research interest. We found that the 3D joint center position can vary over a supraphysiologic range in shoulders with RTSA, and that this variation is primarily in the coronal plane. By relating these geometric variations to muscle, shoulder and clinical function, we hope to establish methods and strategies for predictably obtaining the best clinical and functional outcomes for RTSA patients on a per-subject basis.

Introduction

Wear-related osteolysis continues to be a concern in the long-term outcome and survivorship of total hip arthroplasty (THA) and there continues to be an emphasis on bearing materials that exhibit improved wear profiles. Oxidized zirconium metal (Oxinium®, Smith & Nephew) was developed to reduce the amount of polyethylene wear as compared to cobalt chromium femoral heads, without the risk of brittle fracture seen with older generation ceramics. There are a limited number of retrieval studies evaluating the performance of Oxinium in THA. The aims of this study were 1) to visually assess damage on the surface of a large number of retrieved Oxinium femoral heads, 2) to measure surface roughness of scratches on the surfaces of Oxinium femoral heads, and 3) to use scanning electron microscopy (SEM) to assess the integrity of the oxidized zirconium surface in damaged areas. BIOLOX delta (CeramTec), a ceramic alternative to Oxinium, was included in this study for comparison.

Reverse total shoulder arthroplasty (RTSA) is increasingly used in the United States since approval by the FDA in 2003. RTSA relieves pain and restores mobility in arthritic rotator cuff deficient shoulders. Though many advantages of RTSA have been demonstrated, there still are a variety of complications (implant loosening, shoulder impingement, infection, frozen shoulder) making apparent much still is to be learned how RTSA modifies normal shoulder function. The goal of this study was to assess how RTSA affects deltoid muscle moment generating capacity post-surgery using a subject-specific computational model driven by in vivo kinematic data.

A subject-specific 12 degree-of-freedom (DOF) musculoskeletal model was used to analyze the shoulders of 27 subjects (14-RTSA, 12-Normal). The model was modified from the work of Holzbaur et al. to directly input 6 DOF humerus and scapula kinematics obtained using fluoroscopy. Model geometry was scaled according to each subject's skeletal dimensions. In vivo abduction kinematics for each subject were input to their subject-specific model and muscle moment arms for the anterior, lateral and posterior aspects of the deltoid were measured over the arc of motion.

Similar patterns of muscle moment arm changes were observed for normal and RTSA shoulders. The moment arm of the anterior deltoid was positive with the arm at the side and decreased monotonically, crossing zero (the point at which the muscle fibers pass across the joint center) between 50°–60° glenohumeral abduction (Figure 1a). The average moment arm of the lateral deltoid was constant and positive in normal shoulders, but showed a decreasing trend with abduction in RTSA shoulders (Figure 1b). The posterior deltoid moment arm was negative with the arm at the side, and increased monotonically to a positive value with increasing glenohumeral abduction (Figure 1c). Subject-specific moment arm values for RTSA shoulders were highly variable compared to normal shoulders. 2-way repeated measures ANOVA showed significant differences between RTSA and normal shoulders for all three aspects of the deltoid moment arm, where the moment arms in RTSA shoulders were smaller in magnitude.

Shoulder functional capacity is a product of the moment generating ability of the shoulder muscles which, in turn, are a function of the muscle moment arms and muscle forces. Placement of implant components during RTSA can directly affect the geometric relationship between the humerus and scapula and, therefore, the muscle moment arms in the RTSA shoulder. Our results show RTSA shoulders maintain the same muscle moment arm patterns as healthy shoulders, but they show much greater inter-subject variation and smaller moment arm magnitudes. These observations show directly how RTSA configuration and implant placement affect deltoid moment arms, and provide an objective basis for determining optimal implant configuration and surgical placement to maximize RTSA function in a patient-specific manner.

Reverse total shoulder arthroplasty (RTSA) is an increasingly common treatment for osteoarthritic shoulders with irreparable rotator cuff tears. Although very successful in alleviating pain and restoring some function there is little objective information relating geometric changes imposed by the reverse shoulder and the moment generating capacity of the shoulder muscles. Recent modeling studies of reverse shoulders have shown significant variation in deltoid muscle moment arms over varied joint centers for shoulders with RTSA. The goal of this study was to investigate the sensitivity of muscle moment arms as a function of varying the joint center in one representative RTSA subject. We hypothesized there may exist a more beneficial joint implant placement, measured by muscle moment arms, compared to the actual surgical implant placement.

A 12 degree of freedom, subject-specific model was used to represent the shoulder of a patient with RTSA for whom fluoroscopic measurements of scapular and humeral kinematics during abduction had been obtained. The computer model used these abduction kinematics and systematically varied joint center locations over 1521 different perturbations from the surgical placement to determine moment arms for the anterior, lateral and posterior aspects of the deltoid muscle. The joint center was varied from its surgical position ±4 mm in the anterior/posterior direction, 0–24 mm in the medial/lateral direction, and −10 mm to 14 mm in the superior/inferior direction.

The anterior deltoid moment arm varied up to 16mm with center of rotations variations, primarily in the medial/lateral and superior/inferior directions (Figure 2, Table 1(Figure 1)). Similarly, the lateral deltoid moment arm demonstrated variations up to 13 mm, primarily with joint center changes in the anterior/posterior and superior/inferior directions. The posterior deltoid moment arm varied up to 10mm, primarily in early abduction, and was most sensitive to changes of the joint center in demonstrated a sensitivity of 6 mm corresponding to variations in the superior/inferior directions (Figure 2).

The goal of this study was to assess the sensitivity of the deltoid muscle moment arms as a function of joint configuration for an existing RTSA subject. High variations were found for all three deltoid components. Variation over the entire abduction arc was greatest in the anterior and lateral deltoid, while the posterior deltoid moment arm was mostly sensitive to joint center changes early in the abduction arc. Moment arm changes of 10–16mm represent a significant amount of the total deltoid moment arm. This means there is an opportunity to dramatically change the deltoid moments arms through surgical placement of the joint center of rotation. Computational models of the shoulder may help surgeons optimize subject-specific placement of RTSA implants to provide the best possible muscle function, and assist implant designers to configure devices for the best overall performance.

Current modeling techniques have been used to model the Reverse Total Shoulder Arthroplasty (RTSA) to account for the geometric changes implemented after RTSA. Though these models have provided insight into the effects of geometric changes from RTSA these is still a limitation of understanding muscle function after RTSA on a patient-specific basis. The goal of this study sought to overcome this limitation by developing an approach to calibrate patient-specific muscle strength for an RTSA subject.

The approach was performed for both isometric 0° abduction and dynamic abduction. A 12 degree of freedom (DOF) model developed in our previous work was used in conjunction with our clinical data to create a set of patient-specific data (3 dimensional kinematics, muscle activations, muscle moment arms, joint moments, muscle length, muscle velocity, tendon slack length, optimal fiber length, peak isometric force)) that was used in a novel optimization scheme to estimate muscle parameters that correspond to the patient's muscle strength[4]. The optimization varied to minimize the difference between measured(“in vivo”) and predicted joint moments and measured (“in vivo”) and predicted muscle activations. The predicted joint moments were constructed as a summation of muscle moments. The nested optimization was implemented within matlab (Mathworks). The optimization yields a set of muscle parameters that correspond to the subject's muscle strength. The abduction activity was optimized.

The maximum activation for the muscles within the model ranged between .03–2.4 (Figure 1). The maximum joint moment produced was 11 newton-meters. The joint moments were reproduced to an value of 1. Muscle parameters were calculated for both isometric and dynamic abduction (Figure 2). The muscle parameters produced provided a feasible solution to reproduce the joint moments seen “in vivo” (Figure 3).

Current modeling techniques of the upper extremity focus primarily on geometry. In efforts to create patient-specific models we have developed a framework to predict subject-specific strength characteristics. In order to fully understand muscle function we need muscle parameters that correspond to the subject's strength. This effort in conjunction with patient-specific models that incorporate the patient's joint configurations, kinematics and bone anatomy hopes to provide a framework to gain insight into muscle tensioning effects after RTSA. With this framework improvements can be made to the surgical implementation and design of RTSA to improve surgical outcomes.

Background

Glenoid component aseptic loosening is the most common source of total shoulder arthroplasty (TSA) revision. In an attempt to strengthen cemented glenoid component fixation, divergent pegged glenoids were designed. Divergent peg creation was intended to increase cement purchase and provide resistance to component rocking.

Objectives

Effective analgesia after total knee arthroplasty (TKA) improves patient satisfaction, mobility and expedites discharge. This study assessed whether continuous femoral nerve infusion (CFNI) was superior to a single-shot femoral nerve block in primary TKA surgery completed under subarachnoid blockade including morphine.

Summary Statement

Reverse shoulder design philosophy can impact external rotation moment arms. Lateralizing the humerus can increase the external rotator moment arms relative to normal anatomy.

Introduction:

Concerns remain regarding both the toughness of alumina, and stability of zirconia ceramics in total hip arthroplasty (THA). A zirconia-toughened alumina (ZTA) bearing has been introduced, in which yttria-stabilized, zirconia polycrystals are uniformly distributed in an alumina matrix. The goal is to combine the wear resistance of alumina with the toughness of zirconia. Zirconia's toughness is attributed to a tetragonal to monoclinic (t-m) phase transformation that occurs in response to a crack, hindering its propagation; however, it might decrease material stability. The purposes of this study were to investigate the degree and position of metal transfer, and the occurrence of t-m phase transformation using Raman spectroscopy, in a series of retrieved, ZTA femoral heads.

Background:

The use of reverse total shoulder arthroplasty (RTSA) has been increasing around the world. However, because of concerns over lack of internal rotation with the reverse prosthesis and the resultant difficulties with activities of daily living (ADLs), many have recommended against performing bilateral RTSA.

Purpose:

While the use of press-fit humeral components has been accepted in total shoulder arthroplasty, few studies focus on the outcomes after uncemented reverse total shoulder arthroplasty. The purpose of this study is to compare the radiographic and functional results of uncemented and cemented humeral fixation in reverse total shoulder arthroplasty.

Retrieval analysis has been valuable in the assessment of in-vivo surface damage of orthopedic devices. Historically, subjective techniques were used to grade damage on the implant's surface. Microscopy improved the ability to localize and quantify damage, but cannot measure volumetric wear due to this damage. Laser scanning provides volumetric wear, but lacks image data. Recent techniques superimpose image data on laser scan data (photorendering) and combine the strengths of both methods. Our goal is to use such methods to improve our damage assessment and potentially correlate this assessment to volumetric wear.

This project focused on two areas: image-stitching and photorendering. Image-stitching registers multiple images into large-scale high-resolution composites. Six total disc replacement components were imaged with a digital microscope (Moticam 2, Motic). Three sets were taken of each component: a single template at 10x zoom (1×1), a 4-image composite at 18x zoom (2×2), and a 9-image composite at 18x zoom (3×3). The 2×2 and 3×3 sets were image-stitched to resemble their template counterpart. Measurement error was defined using common pixels identified between the composite and template images for comparison with a semi-automated feature detection algorithm (Figure 1).

For photorendering, a pilot study was performed on a single retrieved tibial bearing. The component was imaged with a digital microscope (VHX-2000, Keyence) under a 3D image-stitching setting, providing a high-resolution photo embedded with height values. MATLAB was used to convert the image into a photo-rendered point cloud approximating the surfaces. The component was then laser scanned, creating a 3D point cloud with resolution 0.127 mm. The photo-rendered point cloud data was registered to the laser scan data using an iterative closest point algorithm (Geomagic Studio, Geomagic).

An analysis of all composite images showed a mean error of 0.221 mm. Figure 2 compares regions of images for the template, 2×2, and 3×3 composites. Zooming in shows the effect of the increased resolution contained in the composite. The 2×2 and 3×3 composites had mean errors of 0.231 mm and 0.209 mm, respectively; these were not significantly different. Comparisons among image types showed that components with less features exhibited larger errors during image-stitching. Figure 3 shows images resulting from each step of the photorendering process. The final image of the figure shows a qualitative result of our ability to photorender the tibial bearing surface of the component.

While combining microscopy and laser scan data works anecdotally, further analyses must be performed to assure the robustness of the technique. The digital microscope's embedded image-stitching software is limited in its maximum field of view; we look to extend this by taking multiple scans and using in-house software to generate a composite of a whole implant. The improved resolution provided by microscopy offer an opportunity to automate damage assessment, yielding damage mapped images which can also be overlaid on laser scan data. This may provide a means to better quantify observed damage and yield meaningful correlations with volumetric loss due to wear.