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The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 2 | Pages 202 - 208
1 Feb 2010
Berton C Girard J Krantz N Migaud H

Implantation of a large-diameter femoral head prosthesis with a metal-on-metal bearing surface reduces the risk of dislocation, increases the range of movement, minimises the risk of impingement and, in theory, results in little wear.

Between February 2004 and March 2007 we implanted 100 consecutive total hip replacements with a metal-on-metal bearing and a large femoral head into 92 patients. There were 51 men and 41 women with a mean age of 50 years (18 to 70) at the time of surgery.

Outcome was assessed using the Western Ontario McMaster University osteoarthritis index and the Harris hip score as well as the Devane activity score. These all improved significantly (p < 0.0001). At the last follow-up there were no cases of dislocation, no impingement, a good range of movement and no osteolysis, but seven revisions, two for infection and five for aseptic loosening. The probability of groin pain increased if the other acetabular component inclination exceeded 50° (p = 0.0007). At 4.8 years of follow-up, the projected survival of the Durom acetabular component, with revision for any reason, was 92.4% (sd 2.8) (95% confidence interval 89.6 to 95.2).

The design of the component made it difficult both to orientate and seat, which when combined with a poor porous coating, produced unpredictable fixation and a low survival at five years.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 1 | Pages 12 - 19
1 Jan 2010
Vendittoli P Roy A Mottard S Girard J Lusignan D Lavigne M

We have updated our previous randomised controlled trial comparing release of chromium (Cr) and cobalt (Co) ions and included levels of titanium (Ti) ions. We have compared the findings from 28 mm metal-on-metal total hip replacement, performed using titanium CLS/Spotorno femoral components and titanium AlloFit acetabular components with Metasul bearings, with Durom hip resurfacing using a Metasul articulation or bearing and a titanium plasma-sprayed coating for fixation of the acetabular component.

Although significantly higher blood ion levels of Cr and Co were observed at three months in the resurfaced group than in total hip replacement, no significant difference was found at two years post-operatively for Cr, 1.58 μg/L and 1.62 μg/L respectively (p = 0.819) and for Co, 0.67 μg/L and 0.94 μg/L respectively (p = 0.207). A steady state was reached at one year in the resurfaced group and after three months in the total hip replacement group. Interestingly, Ti, which is not part of the bearing surfaces with its release resulting from metal corrosion, had significantly elevated ion levels after implantation in both groups. The hip resurfacing group had significantly higher Ti levels than the total hip replacement group for all periods of follow-up. At two years the mean blood levels of Ti ions were 1.87 μg/L in hip resurfacing and and 1.30 μg/L in total hip replacement (p = 0.001).

The study confirms even with different bearing diameters and clearances, hip replacement and 28 mm metal-on-metal total hip replacement produced similar Cr and Co metal ion levels in this randomised controlled trial study design, but apart from wear on bearing surfaces, passive corrosion of exposed metallic surfaces is a factor which influences ion concentrations. Ti plasma spray coating the acetabular components for hip resurfacing produces significantly higher release of Ti than Ti grit-blasted surfaces in total hip replacement.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 222 - 222
1 May 2009
Lavigne M Girard J Mottard S Roy A Vendittoli PA
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The purpose of this study was to compare the post operative ROM of patients randomised between SRA and 28mm THA.

Restoration of normal ROM has been proposed as an advantage of hip resurfacing (SRA) over THA and is due to the use of larger diameter femoral heads. However, the head-neck diameter ratio, which is an important factor governing ROM, would in theory allow more ROM with THA (28mm head/14mm neck = ratio 2:1) versus SRA (approximate ratio 1.3–2.0:1).

Patients were randomised between SRA and THA. Osseous landmarks were identified with a marker pen. Both ASIS served as the reference line for the pelvis position. Digital photographs of hip motion were taken and a blinded rater (with respect to the side and type of surgery) performed range of motion testing on the operated and normal side. Pre-study validation of ROM measurement method with a software program revealed high intra and inter observer reliability.

Sixty SRA and sixty-two THA were evaluated at minimum follow-up of twelve months. Preoperative ROM and demographic data were similar for both groups. No significant differences (p> 0.05) were found in the total arc of motion (SRA=204.2°, THA=196.5°), arc of rotation (SRA=47.7°, THA=44.3°), flexion-extension arc (SRA=118.1, THA=120.1), abduction-adduction arc (SRA=43.1°, THA=42.9°).

In theory, ROM should have been greater in THA. Fear of instability may have limited ROM recovery potential in THA. Since pre operative soft tissue contracture is an important factor influencing post operative ROM, the complete capsular release performed during SRA may have been an advantage of this technique.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 100 - 100
1 Mar 2009
Migaud H Girard J Trichard T Remy F Soenen M Bachour F Duquennoy A
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Purpose of the study: Theoretically, long-term functional and radiographic degradation is predictable after ankle fusion, but sound evidence from consecutive analysis of the same cohort is lacking. The purpose of this study was to evaluate the same cohort of patients who underwent ankle fusion.

Material and Methods: The cohort included 52 ankle fusions which had been analyzed in 1984 at seven years (2–22 years) of follow-up then again in 2000 using the same evaluation criteria. Among the 52 patients, six were lost to follow-up, 20 had died and one had undergone leg amputation. The second analysis thus included 25 patients (18 men and 7 women), mean age 62±12.6 years (40–94) at the 2000 assessment performed 23±4.5 years (19–36 years) after the fusion. Functional outcome was assessed with the 100-point Duquennoy scale. Osteoarthritis of the subtalar and mediotarsal joints were assessed preoperatively and at follow-up using the same scale.

Results: The functional outcome did not deteriorate significantly between 1984 and 2000. The mean score was 65.8±22.6 (19–92) in 1984 and 64.7±18.3 (34–90) in 2000 (p=0.67). Fifteen patients (60%) had a good or very good outcome at seven years, and 14 (56%) at 23 years. Between 1984 and 2000, ten patients improved their score (on average 10.4 points, range 1–21 points), two had an unchanged score and thirteen a lower score (on average 10 points, range −1 to −24). Ten of these thirteen patients developed severe intercurrent conditions explaining the degradation. At last follow-up, sixteen ankles were pain free or nearly pain free. Twelve patients considered their ankle as a forgotten problem and had no regrets concerning the operation. The evolution of the subtalar joint in 16 cases (nine fusions including five at the same time as the ankle fusion and four performed within four years) showed that all developed early osteoarthrtic degradation with aggravation between 1984 and 2000, leading in the majority of cases to severe degenerative disease. This osteoarthritis was painful in less than one-third of the cases (including the four secondary subtalar fusions and the four sub-talar fusions which were painful at mobilization). The mediotarsal joints degradation was later and less severe than for the subtalar joint with a majority of moderate osteoarthritis. Ten ankles exhibited compensatory hypermobility of the forefoot measured at more than 15° without pain.

Discussion: This long-term follow-up with two successive assessments using the same evaluation criteria did not demonstrated late degradation of function expected after ankle fusion. It did show however the presence of radiographic degradation of the subtalar joint but with little clinical expression at a minimal follow-up of 19 years. There was no need for complementary fusion between 4 and 23 years follow-up.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 104 - 104
1 Mar 2009
PINOIT Y MAY O GIRARD J EDDINE TA LAFFARGUE P MIGAUD H
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Introduction: The anterior pelvic plane (APP), described by Lewinnek, is defined by the following points : anterior iliac spines, pubic symphysis. This plan is mostly considered as vertical in weight bearing and is currently used as the reference to guide cup insertion by means of imageless computer assistance (CAS). However, to our knowledge, there is no data that strongly confirm APP is vertical in weight bearing and how much his orientation is modified with regards operative position, or THA insertion. This study assessed these data by means of a radiological analysis.

Material and Methods: The orientation of the APP was measured with regards to the vertical plane on weight-bearing profile X-rays of the pelvis in 106 subjects including:

1) 82 patients with THA (40 who had at least one dislocation, and 42 matched patients without instability randomly selected, 19 of these 42 underwent a profile X-ray of the pelvis before and after THA insertion)

2) and 24 standard subjects who underwent lying and weight-bearing profile X-rays of the pelvis to assess the modifications of orientation of the pelvis between these two positions.

Results: Thirty-eight percent of the subjects in weight-bearing had an orientation of the APP different of more than ± 5° from vertical plane and 13% were out of the interval ±10°. The orientation of the APP was not significantly different between the groups (standard and THA) nor between the groups who had stable or unstable THA. The orientation of the APP was significantly modified between lying and weight-bearing posture, from a mean of 1,2° lying to −2,25° upright. Under these conditions, 12 subjects presented a variation of more than 7°. Insertion of a THA did not significantly modify the orientation of the APP in weight-bearing among the 19 subjects (variations were small (−1° ± 7° [from – 21° to 8°]), but were more than 5° for 7 of the 19 subjects).

Discussion and Conclusion: Most of the surgeons use the APP as a reference to guide navigation for cup insertion, considering it is vertical in weight-bearing. However, it is not true for 38% with a margin of 10°, which is equivalent to approximately half of the anatomical anteversion of the acetabulum. Standing up produced a significant variation of the orientation of the APP with regards to lying position. These errors that are not integrated by most of the CAS without preoperative CT scans, may produce cam effect or dislocation when the patient is moving to sited position. The variations of APP orientation with regards to vertical plane suggest it is not adequate to guide the CAS insertion of the cup. There is no reliable reference, easily identifiable during surgery that integrates the variations of position of the pelvis. This leads us to promote a new CAS for THA insertion free of reference plane, based on kinematics.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 5 | Pages 674 - 676
1 May 2008
May O Girard J Hurtevent JF Migaud H

Delayed sciatic nerve palsy is uncommon after primary hip replacement. Two kinds of sciatic palsy have been reported with regard to the time of onset: early palsy related to wound haematoma or lumbosacral nerve elongation which occurs between surgery and 18 days, is more frequent than delayed palsy, occurring between 10 and 32 months, which is usually caused by cement extrusion or heat produced by cement polymerisation.

We present two cases of delayed, transient sciatic nerve palsy arising at three weeks and four months after primary cementless arthroplasty, respectively, without haematoma and with a normal lumbar spine. These palsies were possibly caused by excessive tension from minor limb lengthening of 2 cm to 4 cm required to achieve leg-length equality. As the initial symptoms were limited to calf pain and mild numbness in the foot, surgeons should be aware of this mode of onset, particularly when it is delayed after hip replacement. Both patients recovered fully by 12 months after surgery so we did not undertake surgical exploration of the nerve in either patient.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 144 - 145
1 Mar 2008
Lavigne M Vendittoli P Roy A Girard J
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Purpose: Femoral offset restoration is recognised as an important part of THA procedure to reduce the joint reactive force and improve stability. In SRA, femoral offset is often reduced due to the femoral component valgus position. The main objective of this study was to correlate the clinical function of SRA and THA patients with their different biomechanical hip reconstruction (femoral offset).

Methods: 156 patients aged 23 to 65 years old and suffering from advanced hip joint degeneration were randomly assigned to two treatment groups: the THA or SRA group. All surgeries were performed through a posterior approach. Standardized pre and post operative antero-posterior radiographs of the pelvis were made and clinical scores were assessed.

Results: Compared to the normal contra lateral side, the femoral offset increased on average 4.85mm (range -2.77 to 11.59mm, SD 3.31) for THA and decreased an average of 3.42mm (range −7.78 to 1.96, SD 2.12) for SRA (p=0.0001). In addition, offset restoration was within lees than 4 mm in 60.0% of the SRA group and 21.8% in the THA group (p=0.0001). There were no differences between the both groups in terms of clinical and subjective scores: the PMA and SF-36 scores were, respectively, in average 17.1 (SD 0.4) and 101 (SD 1.25) for THA and 17.0 (SD 0.4) and 101 (SD 1.14) for SRA. No relation was found between offset restoration and clinical scores for both groups.

Conclusions: In this study, surgeons were less precise reconstructing the femoral offset in the THA group compared to the SRA group. However, femoral offset was lower (reduced) in the SRA in comparison to THA. This significant decreased femoral offset in SRA, seems inherent to the preferential valgus positioning of the femoral component in that technique. The excellent clinical outcome reported with SRA does not suggest that restoring normal offset is as crucial for the success of SRA because no correlation was found between femoral offset and the clinical scores used.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 109 - 109
1 Mar 2008
Girard J Migaud H Chantelot C Laffargue P Duquennoy A
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Thirty-nine cementless hip replacements using metal-on-metal articulation were consecutively implanted in thirty patients less than fifty years of age and compared with a matched control group of cementless replacements using ceramic-on-polyethylene articulation. The Harris hip score at follow-up (minimum five years) for the metal-on-metal was 94.9 (range, 74–100). After the same follow-up, the results of the ceramic-on-polyethylene were significantly worse: nine osteolyses and seven surgical revisions related to wear. Five-year survival rates were 97% +/− 2% for the ceramic-on-polyethylene and 100% for the metal-on-metal. The metal-on-metal may be recommended to prevent wear problems in younger and more active patients.

The aim of the current study was to assess the results of metal-on-metal articulating components inserted as a primary hip replacement in patients under the age of fifty, comparated with a matched control group using ceramic-on-polyethylene.

Patients and methods

The inclusion of patients was: under fifty years of age and a diagnosis of arthrosis or necrosis of the femoral head.

Femoral stem and cup migration was detected. A variation over five millimeters between the follow-up radiographs was considered as migration.

At the follow-up in 2003, the cobalt concentrations in the whole blood were assessed in the metal-on-metal cohort. The detection limit of cobalt in the whole blood was 0.06 μg/L.

None of the components had migration.

At a mean follow-up of sixty-nine months, the median concentration of cobalt in the whole blood was 0.62μg/L. Only eight patients had cobalt levels greater than 1 μg/L.

Considering a reoperation with the exchange of one of the components as end point, the five year survival rates were 100% for the metal-on-metal group and 97% + 2 for the ceramic-on-polyethylene group. Our study suggests that the metal-on-metal articulation gives a significant improvement in terms of resistance to wear when compared with these conventional bearing components. Our results suggest the metal-on-metal articulation with cementless components can be recommended in the young and active patient to prevent the occurrence of wear and osteolysis. A careful assessment of patients with high levels of whole-blood cobalt should be performed.

Funding: Aucun


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 8 | Pages 997 - 1002
1 Aug 2006
Vendittoli P Lavigne M Girard J Roy AG

We have undertaken a prospective, randomised study to compare conservation of acetabular bone after total hip replacement and resurfacing arthroplasty of the hip. We randomly assigned 210 hips to one of the two treatment groups. Uncemented, press-fit acetabular components were used for both.

No significant difference was found in the mean diameter of acetabular implant inserted in the groups (54.74 mm for total hip replacement and 54.90 mm for resurfacing arthroplasty). In seven resurfacing procedures (6.8%), the surgeon used a larger size of component in order to match the corresponding diameter of the femoral component.

With resurfacing arthroplasty, conservation of bone is clearly advantageous on the femoral side. Our study has shown that, with a specific design of acetabular implant and by following a careful surgical technique, removal of bone on the acetabular side is comparable with that of total hip replacement.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 6 | Pages 721 - 726
1 Jun 2006
Girard J Lavigne M Vendittoli P Roy AG

We have compared the biomechanical nature of the reconstruction of the hip in conventional total hip arthroplasty (THA) and surface replacement arthroplasty (SRA) in a randomised study involving 120 patients undergoing unilateral primary hip replacement. The contralateral hip was used as a control.

Post-operatively, the femoral offset was significantly increased with THA (mean 5.1 mm; −2.8 to 11.6) and decreased with SRA (mean −3.3 mm; −8.9 to 8.2). Femoral offset was restored within sd 4 mm in 14 (25%) of those with THA and in 28 (57%) of the patients receiving SRA (p < 0.001). In the THA group, the leg was lengthened by a mean of 2.6 mm (−6.04 to +12.9), whereas it was shortened by a mean of 1.9 mm (−7.1 to +2.05) in the SRA group, compared with the contralateral side. Leg-length inequality was restored within sd 4 mm in 42 (86%) of the SRA and 33 (60%) of the THA patients. The radiological parameters of acetabular reconstruction were similar in both groups.

Restoration of the normal proximal femoral anatomy was more precise with SRA. The enhanced stability afforded by the use of a large-diameter femoral head avoided over-lengthening of the limb or increased offset to improve soft-tissue tension as occurs sometimes in THA. In a subgroup of patients with significant pre-operative deformity, restoration of the normal hip anatomy with lower pre-operative femoral offset or significant shortening of the leg was still possible with SRA.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 6 | Pages 838 - 839
1 Jun 2006
VENDITTOLI P LAVIGNE M ROY A GIRARD J


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 6 | Pages 818 - 821
1 Jun 2006
Girard J Vendittoli P Lavigne M Roy AG

A 34-year-old woman with a benign form of osteopetrosis developed osteoarthritis of the hip. In order to avoid the difficulties associated with inserting the femoral component of a conventional total hip arthroplasty, a hybrid metal-on-metal resurfacing was performed. There were several technical challenges associated with the procedure, including the sizing of the component, press-fit fixation of the acetabular component and femoral head preparation, as well as trying to avoid a fracture. No surgical complication occurred. After more than a year following surgery, the patient showed excellent clinical function and remained satisfied with the outcome. We conclude that the hybrid metal-on-metal resurfacing arthroplasty represents a valuable option for the treatment of patients with osteopetrosis and secondary hip osteoarthritis.