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Bone & Joint Research
Vol. 8, Issue 12 | Pages 604 - 607
1 Dec 2019
Konan S Abdel MP Haddad FS

There is continued debate as to whether cemented or cementless implants should be utilized in particular cases based upon chronological age. This debate has been rekindled in the UK and other countries by directives mandating certain forms of acetabular and femoral component fixation based exclusively on the chronological age of the patient. This editorial focuses on the literature-based arguments to support the use of cementless total hip arthroplasty (THA), while addressing potential concerns surrounding safety and cost-effectiveness.

Cite this article: Bone Joint Res. 2019;8(12):604–607.


Bone & Joint Research
Vol. 8, Issue 11 | Pages 570 - 572
1 Nov 2019
Ahmed SS Haddad FS


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 60 - 60
1 Oct 2019
Kayani B Konan S Horriat S Haddad FS
Full Access

Introduction

The objective of this study was to assess the effect of PCL resection on flexion-extension gaps, mediolateral soft tissue laxity, fixed flexion deformity (FFD), and limb alignment during posterior-stabilised total knee arthroplasty (TKA).

Methods

This prospective study included 110 patients with symptomatic knee osteoarthritis undergoing primary robotic-arm assisted posterior-stabilised TKA. All operative procedures were performed by a single surgeon using a standard medial parapatellar approach. Optical motion capture technology with fixed femoral and tibial registration pins was used to assess gaps pre- and post-PCL resection in knee extension and 90 degrees knee flexion. This study included 54 males (49.1%) and 56 females (50.9%) with a mean age of 68 ± 6.2 years at time of surgery. Mean preoperative hip-knee-ankle deformity was 6.1 ± 4.4 degrees varus.


Bone & Joint Research
Vol. 8, Issue 10 | Pages 438 - 442
1 Oct 2019
Kayani B Haddad FS


Bone & Joint Research
Vol. 8, Issue 6 | Pages 228 - 231
1 Jun 2019
Kayani B Haddad FS



Bone & Joint Research
Vol. 7, Issue 12 | Pages 636 - 638
1 Dec 2018
Roussot MA Haddad FS


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 19 - 19
1 Oct 2018
Kazarian GS Barrack TN Donaldson MJ Lawrie CM Miller GA Haddad FS Barrack RL
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Introduction

Implant malalignment is an important predictor of prosthetic failure following total knee arthroplasty (TKA). The purpose of this study was to determine the incidence of outliers for common alignment targets and the impact of surgeon volume and experience on the accuracy of implant alignment with current generation manual instrumentation.

Methods

This study was a retrospective, multi-center, radiographic analysis of 1675 consecutive primary uncomplicated TKAs from seven surgeons at three academic and state-funded centers in the US and UK. Surgeons were categorized as “high-volume” (≥50 TKAs/year) and “high-experience” (≥5 years post-fellowship). Femorotibial, tibial varus/valgus, and posterior tibial slope angles were digitally measured using postoperative radiographs. Femorotibial (<2° or >8° valgus), tibial (> ±3° deviation from the neutral axis), and tibial slope (<0° or >7° of flexion for cruciate retaining, <0° or >5° of flexion for posterior stabilized) angle outliers were identified. The proportion of outliers among surgeons in each subgroup was compared.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_13 | Pages 39 - 39
1 Oct 2018
Haddad FS
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The increasing infection burden after hip arthroplasty has seen a growth of two-stage exchange and the use of increasingly powerful antibiotics at the time of this procedure. We have seen an increased number of failed two-stage revisions over the past decade. This study was aimed at clarifying the outcome of failed two-stage exchange arthroplasty after periprosthetic hip infection.

We identified forty-two patients who had undergone at least one prior two-stage revision hip arthroplasty for periprosthetic infection between 2000 and 2012. These patients were referred to our center and treated with a further two-stage exchange. They have been analyzed with a minimum two-year follow-up.

Control of infection at two-year follow-up was seen in 57% of patients. In 43% of patients there are still ongoing issues that either required further surgery or ongoing antibiotic suppression.

A regression analysis was undertaken which suggested that the immunocompromised host and polymicrobial infection were the greatest predictors of failure. The number of previous interventions, the organism involved and the duration of antibiotic therapy after the initial two-stage revision were not linked to the ultimate outcome.

The failure rate of repeat revision two-stage exchange is high and novel methods of treatment including host optimization, immunomodulation, longer interval periods, novel antimicrobial methods and more powerful antibiotic therapies should be investigated.


Bone & Joint Research
Vol. 7, Issue 8 | Pages 508 - 510
1 Aug 2018
Horriat S Haddad FS


The Bone & Joint Journal
Vol. 99-B, Issue 11 | Pages 1420 - 1430
1 Nov 2017
Azboy I Barrack R Thomas AM Haddad FS Parvizi J

The number of arthroplasties being performed increases each year. Patients undergoing an arthroplasty are at risk of venous thromboembolism (VTE) and appropriate prophylaxis has been recommended. However, the optimal protocol and the best agent to minimise VTE under these circumstances are not known. Although many agents may be used, there is a difference in their efficacy and the risk of bleeding. Thus, the selection of a particular agent relies on the balance between the desire to minimise VTE and the attempt to reduce the risk of bleeding, with its undesirable, and occasionally fatal, consequences.

Acetylsalicylic acid (aspirin) is an agent for VTE prophylaxis following arthroplasty. Many studies have shown its efficacy in minimising VTE under these circumstances. It is inexpensive and well-tolerated, and its use does not require routine blood tests. It is also a ‘milder’ agent and unlikely to result in haematoma formation, which may increase both the risk of infection and the need for further surgery. Aspirin is also unlikely to result in persistent wound drainage, which has been shown to be associated with the use of agents such as low-molecular-weight heparin (LMWH) and other more aggressive agents.

The main objective of this review was to summarise the current evidence relating to the efficacy of aspirin as a VTE prophylaxis following arthroplasty, and to address some of the common questions about its use.

There is convincing evidence that, taking all factors into account, aspirin is an effective, inexpensive, and safe form of VTE following arthroplasty in patients without a major risk factor for VTE, such as previous VTE.

Cite this article: Bone Joint J 2017;99-B:1420–30.


The Bone & Joint Journal
Vol. 98-B, Issue 10_Supple_B | Pages 11 - 15
1 Oct 2016
Konan S Haddad FS

Aims

Medial unicompartmental knee arthroplasty (UKA) is associated with successful outcomes in carefully selected patient cohorts. We hypothesised that severity and location of patellofemoral cartilage lesions significantly influences functional outcome after Oxford medial compartmental knee arthroplasty.

Patients and Methods

We reviewed 100 consecutive UKAs at minimum eight-year follow-up (96 to 132). A single surgeon performed all procedures. Patients were selected based on clinical and plain radiographic assessment. All patients had end-stage medial compartment osteoarthritis (OA) with sparing of the lateral compartment and intact anterior cruciate ligaments. None of the patients had end-stage patellofemoral OA, but patients with anterior knee pain or partial thickness chondral loss were not excluded. There were 57 male and 43 female patients. The mean age at surgery was 69 years (41 to 82). At surgery the joint was carefully inspected for patellofemoral chondral loss and this was documented based on severity of cartilage loss (0 to 4 Outerbridge grading) and topographic location (medial, lateral, central, and superior or inferior). Functional scores collected included Oxford Knee Score (OKS), patient satisfaction scale and University College Hospital (UCH) knee score. Intraclass correlation was used to compare chondral damage to outcomes.


The Bone & Joint Journal
Vol. 97-B, Issue 10_Supple_A | Pages 16 - 19
1 Oct 2015
Oussedik S Abdel MP Cross MB Haddad FS

Many aspects of total knee arthroplasty have changed since its inception. Modern prosthetic design, better fixation techniques, improved polyethylene wear characteristics and rehabilitation, have all contributed to a large change in revision rates. Arthroplasty patients now expect longevity of their prostheses and demand functional improvement to match. This has led to a re-examination of the long-held belief that mechanical alignment is instrumental to a successful outcome and a focus on restoring healthy joint kinematics. A combination of kinematic restoration and uncemented, adaptable fixation may hold the key to future advances.

Cite this article: Bone Joint J 2015;97-B(10 Suppl A):16–19.


The Bone & Joint Journal
Vol. 97-B, Issue 10_Supple_A | Pages 1 - 2
1 Oct 2015
Thienpont E Haddad FS Argenson JN


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 14 - 14
1 Mar 2013
Benjamin-Laing H Konan S Rayan F Manktelow A Haddad FS
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Infected periprosthetic fractures around total hip arthroplasties are increasingly common and extremely challenging problem. The purpose of the study was to review the experience of two tertiary referral units managing infected periprosthetic femoral fractures using interlocking long-stem femoral prostheses either as temporary functional spacers or as definitive implants.

Methods

A prospective review of 19 patients managed at two tertiary referral units between 2000 and 2011. Each patient was diagnosed and managed according to similar institutional protocols. Investigation through aspiration and biopsy of periprosthetic tissue supplemented haematological tests to confirm infection. The Cannulock uncoated stem was used in 14 cases, and the Kent hip prosthesis in 5 cases. Allograft struts were used in patients with deficient bone stock.

Results

The mean follow-up for the series was a 53 months (range, 24–99 months). 13 patients underwent definitive revision within 7.9 months (range, 6–10 months; SD, 2.2 months). In 6 cases we implanted an extensively porous-coated stem, in 4 cases a tapered distally fixed cementless stem was used, and in 3 cases a proximal femoral replacement was used. There were no reinfections after the second stage revisions in these patients. 2 patients were offered further staged surgery due to persistently raised inflammatory markers but being mobile and relatively painfree declined. They are being managed in the community on oral antibiotics. Satisfactory outcome was noted in all cases, and in 13 cases, revision to a definitive stem was undertaken after successful control of infection and fracture union. The average postoperative Harris Hip score was 83 (range 79–89). All patients returned to their low to moderate premorbid functional state after discharge.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 228 - 228
1 Jun 2012
Sukeik M Haddad FS
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Introduction

Up to 2% of total hip arthroplasties (THA) are still complicated by infection. This leads to dissatisfied patients with poor function, and has far-reaching social and economic consequences. The challenge in these cases is the eradication of infection, the restoration of full function and the prevention of recurrence. We report the outcome of early aggressive debridement in the acutely infected THA.

Methods

We studied 28 consecutive patients referred with acutely infected THA (18 primaries, 10 revisions) which occurred within 6 weeks of the index operation or of haematogenous spread between 1999 and 2006. Microbiology confirmed bacterial colonisation in all cases with 20 early post-operative infections and 8 cases of acute haematogenous spread. Patients with a cemented THA underwent aggressive open debridement, a thorough synovectomy and exchange of all mobile parts. Uncemented THA were treated as a single stage revision with removal of all implants, aggressive debridement and re-implantation of new prosthesis. Antibiotics were continued in all cases until inflammatory markers and the plasma albumin concentration returned to within normal limits.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 115 - 115
1 Jun 2012
Konan S Hossain FS Haddad FS
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Introduction

There have been concerns regarding the quality of training received by Orthopaedic trainees. There has been a reduction in working hours according to the European working times directive. National targets to reduce surgical waiting lists has increased the workload of consultants, further reducing the trainees' surgical experience. Navigation assisted procedures are successfully used in orthopaedics and provides useful feedback to the surgeon regarding precision of implant placement. We investigated the use of navigation aids as an alternative source of training surgical trainees.

Methods

We choose a navigation assisted knee replacement (TKR) model for this study. A first year Orthopaedic registrar level trainee was taught the TKR procedure by a scrubbed consultant in 5 cases. He was then trained in use of non-CT based navigation surgery. The Trainee then performed navigation assisted non-complex primary TKR surgery. A consultant Orthopaedic surgeon was available throughout for advice and support. Data collected included pre and post procedure valgus and varus alignment of the knee, total operative time and WOMAC scores pre and post operatively.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 116 - 116
1 Jun 2012
Konan S Rayan F Meermans G Witt J Haddad FS
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Introduction

In recent years, there has been a significant advancement in our understanding of femoro-acetabular impingement and associated labral and chondral pathology. Surgeons worldwide have demonstrated the successful treatment of these lesions via arthroscopic and open techniques. The aim of this study is to validate a simple and reproducible classification system for acetabular chondral lesions.

Methods

In our classification system, the acetabulum is first divided into 6 zones as described by Ilizalithurri VM et al [Arthroscopy 24(5) 534-539]. The cartilage is then graded as 0 to 4 as follows: Grade 0 – normal articular cartilage lesions; Grade 1 softening or wave sign; Grade 2 - cleavage lesion; Grade 3 - delamination and Grade 4 –exposed bone. The site of the lesion is further typed as A, B or C based on whether the lesion is 1/3 distance from acetabular rim to cotyloid fossa, 1/3 to 2/3 distance from acetabular rim to cotyloid fossa and > 2/3 distance from acetabular rim to cotyloid fossa.

For validating the classification system, six surgeons reviewed 14 hip arthroscopy video clips. All surgeons were provided with written explanation of our classification system. Each surgeon then individually graded the cartilage lesion. A single observer then compared results for observer variability using kappa statistics.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 22 - 22
1 Mar 2012
Sukeik M Dobson M Bridgens A Haddad FS
Full Access

Introduction

Up to 2% of total knee arthroplasties (TKA) are still complicated by infection. This leads to dissatisfied patients with poor function, and has far-reaching social and economic consequences. The challenge in these cases is the eradication of infection, the restoration of full function and the prevention of recurrence.

We report the outcome of prosthesis sparing early aggressive debridement in the acutely infected TKA.

Methods

We studied 29 consecutive patients referred with acutely infected TKA (18 primaries, 11 revisions) which occurred within 6 weeks of the index operation or of haematogenous spread. Microbiology confirmed bacterial colonisation in all cases with 20 early post-operative infections and 9 cases of acute haematogenous spread. All patients underwent aggressive open debridement, a thorough synovectomy and a change of insert. Antibiotics were continued until inflammatory markers and the plasma albumin concentration returned to within normal limits.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 70 - 70
1 Mar 2012
Hossain FS Patel S Tahmassebi J Haddad FS
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Introduction

Unicondylar knee replacements (UKR) may be more effective compared to Total knee replacements (TKR) in unicompartmental arthritis. We report patient outcomes & satisfaction data in an age matched cohort of patients with either a UKR or TKR.

Method

A single unit and single surgeon series of patients were recruited. Data was retrospectively collated for 68 patients with more than 24 months follow-up. UKR was undertaken in patients with isolated medial compartment osteoarthritis; stable ACL and less than grade 3 lateral patellar changes of the Outerbridge classification. TKR was undertaken for the rest. The patients were assessed with validated knee scores including the Total Knee Function Questionnaire (TKFQ) which focuses on recreational & sporting outcomes as well as activities of daily living (ADL). Patient satisfaction and perception of knee normality was measured on a visual analogue scale.