RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS

A. Prodromidis; G. Chloros; G. Thivaios; P. Sutton; V. Veysi; P. Giannoudis; C. Charalambous

doi:10.1302/1358-992X.2022.7.040

Article alerts Social media

Current issue

Knee

RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS

The British Association for Surgery of the Knee (BASK) May 2022 Meeting, Newport, Wales, 17–18 May 2022.

A. Prodromidis
G. Chloros
G. Thivaios
P. Sutton
V. Veysi
P. Giannoudis
C. Charalambous

RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Prodromidis A, Chloros G, Thivaios G, et al. RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Orthop Procs. 2022;104-B(SUPP_7):40-40. doi:10.1302/1358-992X.2022.7.040

Prodromidis, A., et al. “RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS.” Orthopaedic Proceedings, vol. 104-B, no. SUPP_7, 2022, pp. 40-40., https://doi.org/10.1302/1358-992X.2022.7.040

Prodromidis, A., Chloros, G., Thivaios, G., Sutton, P., Veysi, V., Giannoudis, P., & Charalambous, C. (2022). RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Orthopaedic Proceedings, 104-B(SUPP_7), 40-40. https://doi.org/10.1302/1358-992X.2022.7.040

Prodromidis, A., Chloros, G., Thivaios, G., Sutton, P., Veysi, V., Giannoudis, P. et al. (2022) “RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS.” Orthopaedic Proceedings, 104-B(SUPP_7), pp. 40-40. Available at: https://doi.org/10.1302/1358-992X.2022.7.040

Prodromidis, A., G. Chloros, G. Thivaios, P. Sutton, V. Veysi, P. Giannoudis, and C. Charalambous. “RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS.” Orthopaedic Proceedings 104-B, no. SUPP_7 (2022): 40-40. https://doi.org/10.1302/1358-992X.2022.7.040

Prodromidis A, Chloros G, Thivaios G, Sutton P, Veysi V, Giannoudis P, et al. RADIOLUCENT LINES AND BONE RESORPTION FOLLOWING ATTUNE TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Orthop Procs. 2022 Jul 1;104-B(SUPP_7):40-40. https://doi.org/10.1302/1358-992X.2022.7.040

Copy to clipboard

BibTeX

EndNote

RIS

Abstract

Introduction

Higher than expected rates of tibial loosening with the ATTUNE® total knee arthroplasty (TKA) implant has been reported. Component loosening can be associated with the development of radiolucency lines (RLL) and our study aim was to systematically assess the reported rates of these.

Methodology

A systematic search was undertaken using the Cochrane methodology in four online databases. Identified studies were assessed and screened against predetermined inclusion criteria. Meta-analysis was conducted using a random-effects model.

Results

Nine studies (n=2,727 TKAs) from 6,590 titles met the inclusion criteria: 1 Randomised Controlled Trial (n=74), 1 prospective cohort (n=200), 4 retrospective cohort (n=1,639), and 3 case-series (n=814). All used the 2013 ATTUNE® design. In meta-analysis: 8 studies (n=1,440 ATTUNE TKAs) reported an overall prevalence of 11% (95%CI: 6.4-18.3%) for medial tibia RLL; 7 studies (n=940) a 12.3% (95%CI: 4.0-32%) rate of any tibia RLL.; 5 studies (n=736) femoral RLL in 11% (95%CI: 7.2-106.5%) and 7 studies (n=896) any RLL in 20.7% (95%CI: 13.4-30.6%). Meta-analysis of 4 studies (n=1,036) comparing the ATTUNE® with another implant (PFC Sigma®, LCS®, or PERSONA®) showed a higher risk of medial tibia RLL (OR: 2.538; 95%CI: 1.397-4.611, P=0.002) and any RLL (OR: 2.725; 95%CI: 1.302-5.703, P=0.008) in the ATTUNE® group.

Conclusions

The 2013 ATTUNE® TKA system is associated with high rates of radiolucency around the tibial and femoral components. Comparative studies suggesting these rates are more than double those of other systems. Radiolucency may be a herald of component loosening, therefore, close surveillance of this implant is recommended.