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Trauma

WHAT HAPPENS TO BONE SUBSTITUTE? CHERTSEY EXPERIENCE

British Limb Reconstruction Society (BLRS) Annual Conference, Southampton, March 2018



Abstract

Introduction

Anatomical reduction of articular fragments in tibial plateau fractures often leads to a void and there is a need to fill dead space and support the articular fragment. MIIG X3 is marketed as high strength injectable graft, which resorbs and remodels fast. Efficacy and complications related to the use of this bone graft substitute were evaluated in this study

Methods

Between January 2012 and December 2016 we injected calcium sulphate (MIIGX3) in 50 out of 126 consecutive complete articular (AO type C3) tibial plateau fractures that were stabilised with Ilizarov ring fixator. Postoperative CT scans after weight bearing and sequential radiographs were evaluated for union, graft resorption and subsidence. IOWA functional outcome score and complications were recorded.

Results

The median age was 52 (Range 17–87) years. Post-operative CT scans showed leak of the graft into the joint in 11 patients and around the proximal tibiofibular joint in 2 patients but this disappeared spontaneously in all patients. Average time for graft resorption was 3.1 months. Union occurred in all patients. Minor subsidence was noted in almost half of these patients. There was no significant difference in IOWA knee score between those with or without MIIGX3 at final follow up. (p value > 0.05)

Conclusion

MIIGX3 is effective as a void filler providing articular support, eradicating dead space and potentially reducing the risk of infection. Leak in the joint or soft tissue resorbed spontaneously in all cases without complications or need for surgical removal. Its use may also be associated with lack of significant late subsidence.


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