A syndrome of back and loin pain produced by impingement of the lowest rib against the iliac crest is described in six patients. All had noticed a significant loss of height and five had osteoporosis of the vertebral column. It is suggested that mechanical irritation of the lowest rib against the iliac crest was the cause of the pain and that subperiosteal resection of the outer two-thirds of the rib would stop this irritation and relieve the symptoms. The six patients who underwent resection of the twelfth rib all obtained relief of symptoms; in one patient the eleventh rib also was resected. At latest review 5 to 34 months postoperatively there has been no recurrence of symptoms.

Clinical examinations and radiographic skeletal surveys have been carried out in 15 patients with foetal alcohol syndrome. Fusion of the capitate and hamate bones in the carpus was bilateral in one patient and unilateral in two. All three had accessory ossification centres at the proximal ends of both second metacarpals. Two of these patients also had radio-ulnar synostosis. Digital shortening, which was demonstrated by pattern profile analysis, was very variable in degree and anatomical distribution. Other skeletal changes of uncertain significance were a "beaten copper" appearance of the calvarium in four patients, and coxa valga in one other. Diagnosis of the foetal alcohol syndrome warrants consideration in any individual presenting with carpal fusion or with radio-ulnar synostosis.