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The Journal of Bone & Joint Surgery British Volume
Vol. 80-B, Issue 4 | Pages 600 - 606
1 Jul 1998
Garellick G Malchau H Herberts P

We assessed 100 patients with a primary total hip replacement using the Harris hip score and the Nottingham Health Profile at one, three and five years after operation. They were derived from two prospective randomised series of cemented and uncemented replacements.

Both scoring systems correlated highly and were each heavily influenced by the system of functional classification defined by Charnley. After five years both reflected the function of the implant and the general state of the patient. A higher degree of sensitivity is needed to show differences in the performance of an implant in the short and medium term. We do not yet have an ideal system of clinical assessment and the overall function must always be properly assessed.


The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 6 | Pages 884 - 891
1 Nov 1996
Malchau H Herberts P Wang YX Kärrholm J Romanus B

We enrolled 98 patients (107 hips) with a mean age of 47 years (SD 8.6) into a prospective study of the Madreporic Lord THR; 34 hips had primary and 73 secondary osteoarthritis.

After ten years, the survival rate using revision as the endpoint for failure was 70% (±9) for the cup and 98% (±0.3) for the stem. The combined clinical and radiological survival rates were 46% (±11) and 81% (±10), respectively. Osteoporosis due to stress-shielding was observed in the proximal femur. Hips with radiologically dense bone postoperatively showed the most pronounced bone loss.

We recommend continued radiological follow-up of patients with this type of implant to allow revision to be performed before there is severe bony destruction of the pelvis.


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 3 | Pages 377 - 383
1 May 1995
Ryd L Albrektsson B Carlsson L Dansgard F Herberts P Lindstrand A Regner L Toksvig-Larsen S

The tibial components in 143 patients with total knee replacements performed before 1988 were assessed for micromotion using roentgen stereophotogrammetric analysis (RSA) over a period of 13 years. The fixation of the prostheses remained clinically sound in all cases, although revision had been required for other reasons in seven. In a second group taken from all cases with RSA available on our full database to 1990, 15 tibial components had been followed by RSA from the insertion until, 1 to 11 years after the initial arthroplasty, they were revised for mechanical loosening of the tibial component; 12 of these comprised all the loosenings in the base group, thus making a total of 155 consecutive cases, while an additional three were inserted after the base material had been compiled. The mean migration in the first group was about 1 mm at one year, but subsequent migration was slower, reaching a mean of about 1.5 mm after ten years. About one-third migrated continuously throughout follow-up, while two-thirds ceased to migrate after one to two years. In the revision group, 14 components had migrated continuously and at one year significantly more than those in the first group. One revision case lacked the crucial one-year follow-up and could not be classified. These findings suggest that mechanical loosening begins early in the postoperative period. Clinical symptoms which necessitate revision, seen at this stage in 20% of abnormally migrating tibial components, may not appear until up to ten years after the operation.(ABSTRACT TRUNCATED AT 250 WORDS)


The Journal of Bone & Joint Surgery British Volume
Vol. 74-B, Issue 2 | Pages 233 - 238
1 Mar 1992
Albrektsson B Carlsson L Freeman M Herberts P Ryd L

We studied the effect of a layer of cement placed under the tibial component of Freeman-Samuelson total knee prostheses with a metal back and an 80 mm intramedullary stem, using roentgen stereophotogrammetry to measure the migration of the tibial component during one year in 13 uncemented and 16 cemented knees. The addition of cement produced a significant reduction in migration at one year, from a mean of 1.5 mm to one of 0.5 mm (p less than 0.01), including a significant reduction in pure subsidence. One year postoperatively the clinical results were similar between the groups, but, at three years, one uncemented knee had required revision.


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 2 | Pages 252 - 258
1 Mar 1990
Albrektsson B Ryd L Carlsson L Freeman M Herberts P Regner L Selvik G

We studied the effect of a metal tray with an intramedullary stem on the micromotion of the tibial component in total knee arthroplasty. Of 32 uncemented Freeman-Samuelson knee arthroplasties performed in London and Gothenburg, nine had a metal backing and stem added to the tibial component. Micromotion of the tibial components, expressed as migration and inducible displacement, was analysed using roentgen stereophotogrammetric analysis up to two years follow-up. The addition of a metal back and a 110 mm stem to the standard polyethylene component significantly reduced both migration over two years and inducible displacement.


The Journal of Bone & Joint Surgery British Volume
Vol. 60-B, Issue 4 | Pages 552 - 560
1 Nov 1978
Herberts P Almstrom C Caine K

A control system for a multifunctional hand prosthesis, which requires a minimum of training for the amputee, has been developed. The great advantage of the pattern recognition technique in making it possible to control as many as six prosthetic movements has prompted this study. The development of a complete miniaturised system has allowed a clinical trial on four patients. Two different tests have been employed to evaluate this system: an objective computer test and a test representing activities of daily living (ADL test). The computer test shows that a high rate of correct recognition is obtained immediately after the prosthesis is applied to the amputee. The ADL test shows that forearm rotation, and flexion and extension of the wrist are used in most activities, indicating that few compensatory movements are performed. It is suggested that this control system is feasible and that long periods of training are unnecessary.


The Journal of Bone & Joint Surgery British Volume
Vol. 50-B, Issue 4 | Pages 780 - 791
1 Nov 1968
Herberts P Kadefors R Kaiser E Petersén I

1. Experience with a refined type of implantable electrode for the myo-electric control of externally powered prostheses is reported.

2. The electrodes are externally energised by electromagnetic induction and therefore do not contain any battery cells. The myo-potentials are transmitted in frequency-modulated form and detected by a receiver placed on the skin. The implantable electrode, measuring 5x11x4 millimetres, is encapsulated in epoxy resin.

3. Six electrodes have been implanted in the forearms of two normal subjects and two below-elbow amputees. The time of implantation ranged from three to fifteen months. Macroscopically, a fibrous capsule developed around the electrodes. Histological examination showed a capsule of granulation tissue of varying thickness with slight inflammatory reaction and foreign-body giant cells.

4. In all cases except one the signals received have been of high quality as ascertained by conventional electromyography and frequency analysis. There has been no significant deterioration in signal quality during the follow-up periods.

5. The major source of failure was fatigue fracture of the gold wires making contact with the body tissues. In one case, however, the electrode was still functioning normally at the time of removal fifteen months after insertion.

6. The patients have not been inconvenienced either by the operative procedures or by the presence of the electrodes in the tissues.