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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_6 | Pages 44 - 44
1 May 2021
Zenios M Oyadiji T Zamini-Farahani A
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Introduction

In my paediatric Orthopaedic practice I use Kirchner wires for the fixation of the TSF on bone. I noted a significant percentage of wire loosening during the post-operative period. The aim of this project was to establish the effectiveness of the wire clamping mechanism and find ways to reduce the incidence of wire loosening when using the TSF.

Materials and Methods

In the first instance wire slippage was measured intra-operatively after the tensioner was removed using an intra-operative professional camera. Following this study mechanical tests were performed in the lab measuring the pull out properties of Kirchner wires using different bolts and different torque levels in order to tighten the wire on the fixator.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_6 | Pages 45 - 45
1 May 2021
Zenios M Oyadiji T Zamani-Farahani A
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Introduction

A clinical case of catastrophic ring failure in a 13 year old autistic overweight patient during treatment for tibial lengthening and deformity using a Taylor Spatial Frame is reported. Ring failure was noted during the later stages of bone healing and the frame was removed. The clinical outcome was not affected by the catastrophic ring failure.

The photograph of the deformed ring is presented below:

Materials and Methods

The patient's notes and X-rays were reviewed and a macroscopic examination of the deformed ring was performed. Mechanical tests of different Taylor Spatial frame constructs were performed in an attempt to simulate the deformity that was clinically observed. Different constructs of TSF of different ring sizes were fixed to polyurethane cylinders simulating bone, were mechanically tested to failure and load/deflection curves were produced.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_3 | Pages 16 - 16
1 Jan 2013
Zenios M Zamani F Oyadiji S
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Purpose of the study

The aim of this mechanical study was to investigate the ability of cannulated fixation bolts to stop wire slippage in Ilizarov circular external fixators.

Methods and Results

Three types of cannulated fixation bolts (Smith and Nephew, Orthofix and one designed by the authors) were tested on Ilizarov rings to compare their performance. Three levels of bolt torques were applied and the wires were pulled to measure the load at which the wire will start to slip or fail. It was revealed that the initial resistance to slippage is due to plastic deformation of the wire under the clamp and is in fact governed by the size of this deformation. The slippage was found to occur in a slip/stick fashion, as the plastic deformation was propagated along the wire.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 146 - 146
1 Jan 2013
Ul Islam S Henry A Khan T Davis N Zenios M
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Introduction

Through the paediatric LCP Hip plating system, the highly successful technique of the locking compression plate used in adult surgery, has been incorporated in a system dedicated to paediatrics. The purpose of this study was to review the outcome of the paediatric LCP Hip plate use in children, both with and without neuromuscular disease, for fixation of proximal femoral osteotomy for a variety of indications.

Materials and methods

We retrospectively reviewed the notes and radiographs of all those children who have had Paediatric LCP Hip Plate for the fixation of proximal femoral osteotomy and proximal femur fractures in our institution, between October 2007 and July 2010, for their clinical progress, mobilization status, radiological healing and any complications.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_3 | Pages 2 - 2
1 Jan 2013
Wells-Cole E Ali F Fines D Griffiths A Zenios M
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The aim of this retrospective study is to compare the different anaesthetic techniques in children undergoing circular frame application for lengthening and deformity correction. Data was collected from 68 cases on severe pain episodes, postoperative duration of analgesia, requirement for top-up analgesia, complications and side-effects and number of osteotomies. The three analgesic methods used were morphine infusion (M), epidural analgesia (E) and continuous peripheral nerve blocks (CPNB). There was a significant difference between the number of episodes of severe pain experienced by the patients receiving a morphine infusion when compared to the epidural and CPNB groups (M vs. E p<0.0001, M vs. CPNB p=0.018). CPNB were associated with the lowest incidence of severe pain episodes and top-up analgesia requirements. The difference in the incidence of nausea and vomiting between the methods was approaching significance (p=0.06). A significant difference was found when comparing epidural and morphine infusions (p=0.05). Epidural analgesia was associated with significantly more nausea and vomiting (p=0.023), and motor blockade (p<0.01) than CPNB. The results show the most effective method of post-operative analgesia for our paediatric patients, in light of pain episodes and associated side-effects, is sciatic nerve catheterisation with continuous infusion.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 156 - 156
1 Sep 2012
Lammin K Taylor J Zenios M
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Background

Osteomyelitis can be difficult to diagnose. Unlike septic arthritis no defined diagnostic criteria exist as a guide. Inflammatory markers are frequently utilized at initial presentation, (in addition to white cell count).

Methods

All radiologically confirmed cases of long bone osteomyelitis without septic arthritis, joint effusion or abscess, in paediatric patients, presenting to one hospital over an eighteen-month period were included. These patients were compared with all culture positive septic arthrides presenting to the same hospital within the same time period. Inflammatory markers taken on the day of admission were studied.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXV | Pages 7 - 7
1 Jul 2012
Lammin K Taylor J Zenios M
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Purpose

To assess the initial rise in inflammatory markers in paediatric patients presenting with long bone osteomyelitis and whether this is comparable with that in septic arthritis, and diagnostic.

Methods

All radiologically confirmed cases of long bone osteomyelitis without septic arthritis, joint effusion or abscess, in paediatric patients, presenting to one hospital over an eighteen-month period were included. These patients were compared with all culture positive septic arthritides presenting to the same hospital within the same period. Inflammatory markers taken on the day of admission were studied.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIV | Pages 14 - 14
1 Jul 2012
Islam SU Henry A Khan T Davis N Zenios M
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Through the paediatric LCP Hip plating system (Synthes GmBH Eimattstrasse 3 CH- 4436 Oberdorff), the highly successful technique of the locking compression plate used in adult surgery, has been incorporated in a system dedicated to pediatrics. We are presenting the outcome of the paediatric LCP hip plating system used for a variety of indications in our institution.

We retrospectively reviewed the notes and radiographs of all those children who have had Paediatric LCP Plate for the fixation of proximal femoral osteotomy and proximal femur fractures in our institution, between October 2007 and July 2010, for their clinical progress, mobilization status, radiological healing and any complications.

Forty-three Paediatric LCP hip plates were used in forty patients (24 males and 13 females) for the fixation of proximal femoral osteotomies (n=40) and proximal femur fractures (n=3). The osteotomies were performed for a variety of indications including Perthes disease, developmental dysplasia of hip, Cerebral Palsy, Down's syndrome, coxa vara, Leg length discrepancy and previous failed treatment of Slipped Upper Femoral Epiphysis.

Twenty-five children were allowed touch to full weight bearing post operatively. Two were kept non-weight bearing for 6 weeks. The remaining 13 children were treated in hip spica due to simultaneous pelvic osteotomy or multilevel surgery for cerebral palsy.

All osteotomies and fractures radiologically healed within 6 months (majority [n=40] within 3 months). There was no statistically significant difference (p= 0.45) in the neck shaft angle between the immediately postoperative and final x-rays after completion of bone healing.

Among the children treated without hip spica, 1 child suffered a periprosthetic fracture. Of the children treated in hip spica, 2 had pressure sores, 3 had osteoporotic distal femur fractures and 2 had posterior subluxations requiring further intervention.

There were no implant related complications.

The Paediatric LCP Hip Plate provides a stable and reliable fixation of the proximal femoral osteotomy performed for a variety of paediatric orthopaedic conditions.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 60 - 60
1 Mar 2012
Zenios M Ramachandran M Milne B Little D Smith N
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The aims of this study were (1) to assess whether rotational stability testing in Gartland III supracondylar fractures can be used intra-operatively in order to assess fracture stability following fixation with lateral-entry wires and (2) to quantify the incidence of rotational instability following lateral-entry wire fixation in Gartland type III supracondylar humeral fractures in children.

Twenty-one consecutive patients admitted with Grade III supracondylar fractures at the Children's Hospital at Westmead were surgically treated according to a predetermined protocol. Following closed fracture reduction, 2 lateral-entry wires were inserted under radiographic control. Stability was then assessed by comparing lateral x-ray images in internal and external rotation. If the fracture was found to be rotationally unstable by the operating surgeon, a third lateral-entry wire was inserted and images repeated. A medial wire was used only if instability was demonstrated after the insertion of three lateral wires.

Rotational stability was achieved with two lateral-entry wires in 6 cases, three lateral-entry wires in 10 cases and with an additional medial wire in 5 cases. Our results were compared to a control group of 24 patients treated at our hospital prior to introduction of this protocol. No patients returned to theatre following introduction of our protocol as opposed to 6 patients in the control group. On analysis of radiographs, the protocol resulted in significantly less fracture position loss as evidenced by change in Baumann's angle (p<0.05) and lateral rotational percentage (p<0.05).

We conclude that the introduction of rotational stability testing allows intra-operative assessment of fracture fixation. Supracondylar fractures that are rotationally stable intra-operatively following wire fixation are unlikely to displace post-operatively. Only a small proportion (26%) of these fractures were rotationally stable with 2 lateral-entry wires. This may be a reflection of either the fracture configuration or inability to adequately engage the medial column.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 11 | Pages 1562 - 1567
1 Nov 2011
Wells-Cole E Griffiths A Fines D Zenios M

This retrospective study compared post-operative epidural analgesia (E), continuous peripheral nerve blocks (CPNB) and morphine infusion (M) in 68 children undergoing limb reconstruction with circular frames. The data collected included episodes of severe pain, post-operative duration of analgesia, requirement for top-up analgesia, number of osteotomies, side effects and complications. There was a significant difference between the number of episodes of severe pain in patients receiving a morphine infusion and those receiving epidurals or CPNB (M vs E, p < 0.0001; M vs CPNB, p = 0.018). The CPNB group was associated with the lowest incidence of episodes of severe pain and top-up analgesia. Epidural analgesia was associated with significantly more nausea and vomiting than morphine infusion (p = 0.053) and CPNB (p = 0.023). It also had a significantly higher incidence of motor blockade than CPNB (p < 0.01). We found that the most effective method of post-operative analgesia for children undergoing lower limb reconstruction was sciatic nerve catheterisation and continuous infusion.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 10 | Pages 1369 - 1374
1 Oct 2007
Nelson D Zenios M Ward K Ramachandran M Little DG

The deformity index is a new radiological measurement of the degree of deformity of the femoral head in unilateral Perthes’ disease. Its values represent a continuous outcome measure of deformity incorporating changes in femoral epiphyseal height and width compared with the unaffected side. The sphericity of the femoral head in 30 radiographs (ten normal and 20 from patients with Perthes’ disease) were rated blindly as normal, mild, moderate or severe by three observers. Further blinded measurements of the deformity index were made on two further occasions with intervals of one month.

There was good agreement between the deformity index score and the subjective grading of deformity. Intra- and interobserver agreement for the deformity index was high. The intraobserver intraclass correlation coefficient for each observer was 0.98, 0.99 and 0.97, respectively, while the interobserver intraclass correlation coefficient was 0.98 for the first and 0.97 for the second set of calculations.

We also reviewed retrospectively 96 radiographs of children with Perthes’ disease, who were part of a multicentre trial which followed them to skeletal maturity. We found that the deformity index at two years correlated well with the Stulberg grading at skeletal maturity. A deformity index value above 0.3 was associated with the development of an aspherical femoral head. Using a deformity index value of 0.3 to divide groups for risk gives a sensitivity of 80% and specificity of 81% for predicting a Stulberg grade of III or IV.

We conclude that the deformity index at two years is a valid and reliable radiological outcome measure in unilateral Perthes’ disease.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 11 | Pages 1541 - 1544
1 Nov 2005
Zenios M Sampath J Cole C Khan T Galasko CSB

Subluxation of the hip is common in patients with intermediate spinal muscular atrophy. This retrospective study aimed to investigate the influence of surgery on pain and function, as well as the natural history of subluxed hips which were treated conservatively. Thirty patients were assessed clinically and radiologically. Of the nine who underwent surgery only one reported satisfaction and four had recurrent subluxation. Of the 21 patients who had no surgery, 18 had subluxation at the latest follow-up, but only one reported pain in the hip. We conclude that surgery for subluxation of the hip in these patients is not justified.


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 8 | Pages 1208 - 1209
1 Nov 2003
KIM WY ZENIOS M MUDDU BN


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 250 - 250
1 Mar 2003
Zenios M Dalal R
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Although it is generally accepted that surgical treatment is the treatment of choice in chronic TA ruptures, therapeutic options are difficult. Traditional options include grafts (natural, allografts and synthetic grafts) and end to end repair. Natural grafts described include fascia lata and plantaris tendon. Synthetic materials such as Dacrongrafts, Marlex mesh and carbon fibers have been used. There are significant complications from graft and end to end repair. These include wound necrosis, delayed union, infection, foreign body reaction and devastating tissue loss. Also functional results are suboptimal after delayed reconstruction.

Tendon transfer is another method that has been described for the treatment of these injuries. The tendons used were the flexor hallucis lomgus, flexor digitorum longus and the peronei . The FHL tendon transfer is considered advantageous to other tendon transfers because it is stronger, its axis of force is close to that of the TA and harvesting the tendon is easy and unlikely to cause any complications.

We report excellent results following four operations in three patients treated with flexor hallucis longus tendon transfer for chronic Achilles tendon ruptures. All patients were on long term steroid treatment and an end to end repair would have been associated with a high complication rate.

We believe that FHL transfer to replace the TA is a low morbidity alternative which gives good to excellent results in individuals with low to moderate demand.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 162 - 162
1 Jul 2002
Zenios M Johnson DS Clayson AD Kay P
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The aim of this randomised prospective study was to establish whether the use of knee splints following total knee replacement is necessary.

The study included 81 patients undergoing total knee replacement who were randomised into a ‘splint’ and a ‘no splint’ group postoperatively. Patients in the ‘splint’ group had their knee splinted in extension in the early post-operative period but the splint was removed for the patients to do exercise. Splintage was completely removed when the patient could straight leg raise. Patients in the ‘no splint’ group had a wool and crepe bandage applied around their knee and allowed to fully mobilise from the first postoperative day. The following parameters were recorded: The range of movement preoperatively, 5 days post-operatively and 6 weeks postoperatively; the length of time to straight leg raise; the blood drained from the wound. and the amount of postoperative analgesia required.

Using the unpaired 2 tailed t-test it was found that patients in the four ‘no splint’ group achieved significantly greater flexion at 5 days and 6 weeks post-operatively but drained significantly more blood from the wound. Transfusion requirements were similar in the two groups. There was no other significant difference in the parameters measured between the two groups.

In conclusion we found no evidence to advocate the use of knee splints following total knee arthroplasty.