Electrospinning of (bio)polymers is a well acknowledged technology used by scientists all over the world to manufacture scaffolds for tissue engineering & 3D cell culture purposes. The ability to control key parameters such as fibre diameter and fibre orientation allow the generation of highly specific scaffolds that closely mimic the native extracellular matrix. Despite the popularity in the R&D lab, the technology itself has only recently seen acceptance as a method for manufacturing clinical-grade medical devices. Subsequently, never before have more electrospun materials obtained market approval (FDA/CE) and are in clinical trials. In this presentation, we share our experience as a manufacturer of clinical-grade medical devices via electrospinning and give insight into the possible applications in orthopaedics.