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Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 42 - 42
1 Aug 2018
Malchau E Rolfson O Grant P Thanner J Karlsson M Mohaddes M
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Arthroplasty registries have played a key role in the treatment of patients with various joint diseases and conditions since their conception. Swedish hip and knee arthroplasty registries were initiated in late 1970's. The main aim of registries was to create feedback to surgeons. During the last two decades with introduction of patient reported outcomes, data from registries have been increasingly used to compare caregivers and to improve quality of health care. According to the Swedish Hip Arthroplasty Register (SHAR) Sahlgrenska University Hospital had been underperforming during years 2006–2012. In order to improve the outcomes a systematic data driven approach using local and national registries, based on value based management was undertaken.

Representatives from all categories of healthcare staff and patients were invited to join a newly initiated group. The group was asked to define which measurement that contributed most to improve healthcare. Data from SHAR and local registries were used and seventeen different areas of improvement were identified. Several workgroups were initiated.

Between years 2013 and 2017 there was an increase of 60% in the annual volume of elective THAs. The length of stay decreased from 6.4 days to 1.8 days. Satisfaction with outcome of surgery increased from 76% to 90%. Adverse events decreased from 28% to 10%. The risk of re-operations within 2 years decreased from 2.4% to 1.9%.

Data from a national and a local registry were used to identify and implement changes in a large university hospital. Engaging member of staff and creating a graphical tool for continuous feedback drastically improved the quality of care whilst increasing the availability of hip replacements and reducing costs. This project demonstrates the power of registry data and a patient centered approach in engaging staff and improving healthcare.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 447 - 447
1 Sep 2009
Thien T Thanner J Kärrholm J
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Earlier reports have shown that surface treatment influences the survivorship of tapered hip implants. To assess the role of surface finish for other stem shapes we evaluated three modifications of the Lubinus SP2 stem.

Eighty patients (31 male, 49 female, 68 (46–78 years), 84 hips) with non-inflammatory arthrosis randomly received either stem type: cemented matte (M, standard design), polymethylmetacrylate-coated (PC) or polished (P, collarless). Component fixation and wear were studied with radiostereometric analysis and the bone mineral density was measured around the stem in 40 patients at 6 months, 1, 2 and 5 years.

The polished design showed increased distal migration at 6 months (Mean and range) P: −0.21mm(−0.52 to 0.09), M: −0.07mm (−0.34 to 0.26), PC: −0.03 (−0.18 to 0.18) and at 5 years P:0.49mm (−1.46 to 0.16), M: −0.18mm (−0.80 to 0.33), PC: −0.12mm (−1.40 to 0.12 (p< 0.0001). This increased subsidence occurred inside the cement mantle. The rotations of the stem did not differ (p> 0.4). Neither did the migration and the wear (p> 0.1). After 1 and 2 years the polished stems had lost significantly less bone mineral in Gruen zones 1, 2, 6 and 7 (p 0.004 to 0.03). After 5 years this difference had disappeared. The Harris Hip Scores did not differ.

A polished surface without collar on an anteverted stem design resulted in increased subsidence of the stem inside the cement mantle. The improved bone remodeling around the polished version seemed to be transient.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 45 - 45
1 Mar 2006
Digas G Kärrholm J Thanner J Malchau H Herberts P
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Introduction: The annual wear rate in polyethylene articulations should be 0.1 mm or less to avoid future osteolysis. Highly Crosslinked polyethylene demonstrates 80–90% wear reduction in hip simulator testing, but the clinical documentation of this new polyethylene is still inadequate. We evaluated the highly crosslink PE in two prospective randomised clinical studies. Patients and Methods: Thirty two patients (12 male, 20 female, 64 hips) with a median age of 48 years (range, 29–70 years) with bilateral primary or secondary arthrosis of the hip received hybrid THA. With liners made of highly cross-link on one side and conventional PE on the other one. Twenty-seven patients in this study have passed 2 years follow up. Further Sixty patients (61 hips) with a median age of 55 years (range, 35–70 years) were randomized to receive either highly crosslink or conventional cemented all PE of the same design. Forty-nine patients have been followed for 3 years. In both studies all patients received Spectron stems with 28mm cobalt-chromium head. Radiostereometric examinations with the patient supine or standing were done at regular intervals. Wear was measured in the supine position from the postoperative week, whereas standing examinations were initiated three months after the operation. Results: The penetration rate was almost identical in the study and control groups in 6 months after the operation. Thereafter the penetration rate levelled out in the 2 groups with highly crosslink PE. At two years the highly crosslink PE liner showed 62% lower proximal penetration and 31% lower total (three-dimensional) penetration when the patients were examined in supine position. The highly crosslink all PE cemented cups showed significantly lower proximal penetration in both position. Discussion: The better wear performance of highly crosslink PE could increase the implant longevity. Longer follow up is needed to evaluate if this new material is associated with less occurrence of osteolysis.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 242 - 242
1 Mar 2004
Digas G Kärrholm J Thanner J Malchau H Herberts P
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Aims: The aim of this study was to evaluate a highly cross-linked polyethylene WIAM in cemented hip arthroplasty. This new polyethylene has been resistant to wear in laboratory tests. Methods: 60 patients (30 women, 30 men) with a median age of 55 years (35–70) and a median weight 82 kg (47–120) were included. All patients received a Spectron femoral stem with a 28 mm head in chrome-cobalt. The patients were randomised to acetabular cups made of either WIAM (electron beam irradiation 9.5 Mrad) or conventional polyethylene (CP) sterilized in inert atmosphere. Radiostereometric examinations (supine) were done 7 days after the operation and after 3, 6 12 and 24 months. Examinations (standing) were performed at 3, 6 12 and 24 months. The migration of the femoral head centre in relation to the polyethylene marker represented the femoral head penetration. Results:. 43 hip (19 WIAM 24 CP) were available for 24 months FU. There were no differences in cup migrations between the two groups. The mean proximal penetration (supine and standing) was less than 0.2 mm at 24 months in both groups p> 0,06 Conclusions: The femoral head penetration during the first two years may be dominated by creep. There is tendency for lower proximal penetration at standing examination in the WIAM group. Futher studies and longer follow up is necessary until highly crosslink polyethylene can be recommended for general use.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 255 - 255
1 Nov 2002
Malchau H Kärrholm J Thanner J Herberts P
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Introduction: In a pioneer study Oonishi et al (1988) found reduced socket wear with the use of polyethylene subjected to high radiation doses. This observation has stimulated the development of a new generation polyethylene. In addition to high radiation doses the plastic is also subjected to various types of heat treatment to reduce the amount of free radicals. The purpose of the present study is to evaluate one of the new highly cross-linked polyethylenes in a randomized controlled study of cemented THA. The hypothesis is that the improved wear resistance will reduce the prevalence of osteolytic lesions with long-term follow-up.

Methods and materials: Patients in clinical and radiographic need of a THR with non-inflammatory osteoarthritis of the hip were randomized in two groups. Group 1 received a cemented Weber cup (Sulzer®, Switzerland) made of highly cross-linked (WIAM) polyethylene, group 2 got a conventional cup. All patients received a cemented Spectron (Smith & Nephew, USA) with a 28mm cobalt-chromium head.

So far 15 patients, (6 male and 9 females) with a median age of 55 years (range 42–62) have been evaluated in group 1 and 14 (9 male and 5 females) with a median age of 55 years (range 45–70) in group 2. The penetration of the femoral heads has so far been measured postoperatively (all hips supine), after 3 month (17 hips supine and standing) and after 6 month (11 hips supine and standing) using radiostereometry.

Results: The median proximal and three-dimensional (3-D) penetration (total wear) 0–6 month (supine position) was almost equal in the two groups. Group 1 had a proximal penetration of 0.08 mm (range 0.00–0.17) and a total penetration of 0.11 mm (range 0.06–0.14). The corresponding values for group 2 were 0,10 mm (0.05–0.21) for proximal penetration and 0.13 mm (0.10–0.16) for total penetration. Between 3 and 6 month the penetration (median values) was 0.04 mm/0.10 mm (proximal/3-D) for group 1 and 0.07 mm/0.12 mm for group 2. With the patients standing we found a proximally migration of the socket (0–6 month) in group 1 of 0,08 mm (−0.07 – 0.21) and 0.12 mm (0.1–0.13) in group 2.

Discussion: Use of a highly cross-linked polyethylene in the socket did not influence the early penetration rate after THR. Early creep of the material is possible explanation.

1-year follow-up on approximately 50% of the patients will be presented at the meeting.