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The Bone & Joint Journal
Vol. 103-B, Issue 7 | Pages 1261 - 1269
1 Jul 2021
Burger JA Zuiderbaan HA Sierevelt IN van Steenbergen L Nolte PA Pearle AD Kerkhoffs GMMJ

Aims

Uncemented mobile bearing designs in medial unicompartmental knee arthroplasty (UKA) have seen an increase over the last decade. However, there are a lack of large-scale studies comparing survivorship of these specific designs to commonly used cemented mobile and fixed bearing designs. The aim of this study was to evaluate the survivorship of these designs.

Methods

A total of 21,610 medial UKAs from 2007 to 2018 were selected from the Dutch Arthroplasty Register. Multivariate Cox regression analyses were used to compare uncemented mobile bearings with cemented mobile and fixed bearings. Adjustments were made for patient and surgical factors, with their interactions being considered. Reasons and type of revision in the first two years after surgery were assessed.


The Bone & Joint Journal
Vol. 102-B, Issue 8 | Pages 1108 - 1108
1 Aug 2020
Burger JA Dooley MS Kleeblad LJ Zuiderbaan HA Pearle AD


The Bone & Joint Journal
Vol. 102-B, Issue 6 | Pages 727 - 735
1 Jun 2020
Burger JA Dooley MS Kleeblad LJ Zuiderbaan HA Pearle AD

Aims

It remains controversial whether patellofemoral joint pathology is a contraindication to lateral unicompartmental knee arthroplasty (UKA). This study aimed to evaluate the effect of preoperative radiological degenerative changes and alignment on patient-reported outcome scores (PROMs) after lateral UKA. Secondarily, the influence of lateral UKA on the alignment of the patellofemoral joint was studied.

Methods

A consecutive series of patients who underwent robotic arm-assisted fixed-bearing lateral UKA with at least two-year follow-up were retrospectively reviewed. Radiological evaluation was conducted to obtain a Kellgren Lawrence (KL) grade, an Altman score, and alignment measurements for each knee. Postoperative PROMs were assessed using the Kujala (Anterior Knee Pain Scale) score, Knee Injury and Osteoarthritis Outcome Score Joint Replacement (KOOS JR), and satisfaction levels.


The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 108 - 116
1 Jan 2020
Burger JA Kleeblad LJ Laas N Pearle AD

Aims

Limited evidence is available on mid-term outcomes of robotic-arm assisted (RA) partial knee arthroplasty (PKA). Therefore, the purpose of this study was to evaluate mid-term survivorship, modes of failure, and patient-reported outcomes of RA PKA.

Methods

A retrospective review of patients who underwent RA PKA between June 2007 and August 2016 was performed. Patients received a fixed-bearing medial or lateral unicompartmental knee arthroplasty (UKA), patellofemoral arthroplasty (PFA), or bicompartmental knee arthroplasty (BiKA; PFA plus medial UKA). All patients completed a questionnaire regarding revision surgery, reoperations, and level of satisfaction. Knee Injury and Osteoarthritis Outcome Scores (KOOS) were assessed using the KOOS for Joint Replacement Junior survey.


The Bone & Joint Journal
Vol. 101-B, Issue 7_Supple_C | Pages 98 - 103
1 Jul 2019
Premkumar A Lovecchio FC Stepan JG Sculco PK Jerabek SA Gonzalez Della Valle A Mayman DJ Pearle AD Alexiades MM Albert TJ Cross MB Haas SB

Aims

The aim of this study was to determine the general postoperative opioid consumption and rate of appropriate disposal of excess opioid prescriptions in patients undergoing primary unilateral total knee arthroplasty (TKA).

Patients and Methods

In total, 112 patients undergoing surgery with one of eight arthroplasty surgeons at a single specialty hospital were prospectively enrolled. Three patients were excluded for undergoing secondary procedures within six weeks. Daily pain levels and opioid consumption, quantity, and disposal patterns for leftover medications were collected for six weeks following surgery using a text-messaging platform.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 65 - 65
1 Oct 2018
Haas SB Premkumar A Lovecchio FC Stepan JG Koch CN Carroll KM Sculco PK Jerabek SA Della Valle AG Mayman DJ Pearle AD Alexiades MM Albert TJ Cross MB
Full Access

Introduction

Over the past few decades, opioid abuse has become a major threat to public health. In 2013 alone, enough opioid prescriptions were written in the United States for every American adult to have their own bottle of pills. Since then, opioid prescribing rates and opioid related deaths have continued to grow, with over 46 people dying on average each day from prescription opioid overdoses in 2016. Orthopaedic surgeons are among the top 5 specialties in the number of opioid prescriptions written. For many common surgeries, such as total knee arthroplasty (TKA), post-discharge prescriptions are based on prescriber habits and opinion. There exists limited data-driven protocols to guide post-operative opioid prescribing practices. The purpose of this prospective study was to determine the average postoperative opioid consumption in patients undergoing primary TKA using a novel mobile text messaging platform. We hypothesized that majority of patients undergoing TKA do not properly dispose of left over pills after surgery.

Methods

95 patients undergoing primary unilateral TKA with one of nine arthroplasty surgeons at a single orthopaedic specialty hospital were prospectively enrolled. Daily pain levels and opioid consumption, and quantity and disposal patterns for left over medications were collected for six weeks following surgery using a novel mobile phone text messaging system. This system automatically queried patients twice a day, storing responses on a secure third-party host that investigators monitored and used to generate data reports in real-time.


The Bone & Joint Journal
Vol. 99-B, Issue 8 | Pages 1028 - 1036
1 Aug 2017
Chawla H Nwachukwu BU van der List JP Eggman AA Pearle AD Ghomrawi HM

Aims

Patellofemoral arthroplasty (PFA) has experienced significant improvements in implant survivorship with second generation designs. This has renewed interest in PFA as an alternative to total knee arthroplasty (TKA) for younger active patients with isolated patellofemoral osteoarthritis (PF OA). We analysed the cost-effectiveness of PFA versus TKA for the management of isolated PF OA in the United States-based population.

Patients and Methods

We used a Markov transition state model to compare cost-effectiveness between PFA and TKA. Simulated patients were aged 60 (base case) and 50 years. Lifetime costs (2015 United States dollars), quality-adjusted life year (QALY) gains and incremental cost-effectiveness ratio (ICER) were calculated from a healthcare payer perspective. Annual rates of revision were derived from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man. Deterministic and probabilistic sensitivity analysis was performed for all parameters against a $50 000/QALY willingness to pay.


The Bone & Joint Journal
Vol. 97-B, Issue 1 | Pages 50 - 55
1 Jan 2015
Zuiderbaan HA Khamaisy S Thein R Nawabi DH Pearle AD

Progressive degenerative changes in the medial compartment of the knee following lateral unicompartmental arthroplasty (UKA) remains a leading indication for revision surgery. The purpose of this study is to evaluate changes in the congruence and joint space width (JSW) of the medial compartment following lateral UKA. The congruence of the medial compartment of 53 knees (24 men, 23 women, mean age 13.1 years; sd 62.1) following lateral UKA was evaluated pre-operatively and six weeks post-operatively, and compared with 41 normal knees (26 men, 15 women, mean age 33.7 years; sd 6.4), using an Interactive closest point algorithm which calculated the congruence index (CI) by performing a rigid transformation that best aligns the digitised tibial and femoral surfaces. Inner, middle and outer JSWs were measured by sub-dividing the medial compartment into four quarters on pre- and post-operative, weight bearing tunnel view radiographs. The mean CI of knees following lateral UKA significantly improved from 0.92 (sd 0.06) pre-operatively to 0.96 (sd 0.02) (p < 0.001) six weeks post-operatively. The mean CI of the healthy control group was 0.99 sd 0.01. Post-operatively, the mean inner JSW increased (p = 0.006) and the outer decreased (p = 0.002). The JSW was restored post-operatively as no significant differences were noted in all three locations compared with the control group (inner JSW p = 0.43; middle JSW p = 0.019, outer JSW p = 0.51).

Our data suggest that a well conducted lateral UKA may improve the congruence and normalise the JSW of the medial compartment, potentially preventing progression of degenerative change.

Cite this article: Bone Joint J 2015;97-B:50–5.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_28 | Pages 63 - 63
1 Aug 2013
Klingenstein G Cross M Plaskos C Li A Nam D Lyman S Pearle AD Mayman D
Full Access

Introduction

The aim of this study was to quantify mid-flexion laxity in a total knee arthroplasty with an elevated joint line, as compared to a native knee and a TKA with joint line maintained. Our hypothesis was joint line elevation of 4mm would increase coronal plane laxity throughout mid-flexion in a pattern distinct from the preoperative knee or in a TKA with native joint line.

Methods

Six fresh-frozen cadaver legs from hip-to-toe underwent TKA with a posterior stabilised implant (APEX PS, OMNIlife Science, Inc.) using a computer navigation system equipped with a robotic cutting-guide, in this controlled laboratory cadaveric study. After the initial tibial and femoral resections were performed, the flexion and extension gaps were balanced using navigation, and a 4mm recut was made in the distal femur. The remaining femoral cuts were made, the femoral component was downsized by resecting an additional 4mm of bone off the posterior condyles, and the polyethylene was increased by 4mm to create a situation of a well-balanced knee with an elevated joint line. The navigation system was used to measure overall coronal plane laxity by measuring the mechanical alignment angle at maximum extension, 30, 45, 60 and 90(of flexion, when applying a standardised varus/valgus load of 9.8Nm across the knee using a 4kg spring-load located at 25cm distal to the knee joint line. Laxity was also measured in the native knee, as well as the native knee after a standard approach during TKA which included a medial release. Coronal plane laxity was defined as the absolute difference (in degrees) between the mean mechanical alignment angle obtained from applying a standardised varus and valgus stress at 0, 30, 45, 60 and 90(.