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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_15 | Pages 60 - 60
7 Nov 2023
Battle J Francis J Patel V Hardman J Anakwe R
Full Access

There is no agreement as to the superiority or specific indications for cast treatment, percutaneous pinning or open fracture fixation for Bennett's fractures of the thumb metacarpal. We undertook this study to compare the outcomes of treatment for patients treated for Bennett's fracture in the medium term.

We reviewed 33 patients treated in our unit for a bennett's fracture to the thumb metacarpal with closed reduction and casting. Each patient was matched with a patient treated surgically. Patients were matched for sex, age, Gedda grade of injury and hand dominance. Patients were reviewed at a minimum of 5-years and 66-patients were reviewed in total. Patients were examined clinically and also asked to complete a DASH questionnaire score and the brief Michigan hand questionnaire. Follow up plain radiographs were taken of the thumb and these were reviewed and graded for degenerative change using the Eaton-Littler score.

Sixty-six patients were included in the study, with 33 in the surgical and non-surgical cohorts respectively. The average age was 39 years old. In each cohort, 12/33 were female, 19/33 were right-handed with 25% of individuals injuring their dominant hand. In each coort there were 16 Grade 1 fractures, 4 Grade 2 and 13 Grade 3 fractures. There was no difference between the surgically treated and cast-treatment cohorts of patients when radiographic arthritis, pinch grip, the brief Michigan Hand Questionnaire and pain were assessed at final review. The surgical cohort had significantly lower DASH scores at final follow-up. There was no significant difference in the normalised bMHQ scores.

Our study was unable to demonstrate superiority of either operative or non-operative fracture stabilization. Patients in the surgical cohort reported superior satisfaction and DASH scores but did not demonstrate any superiority in any other objectively measured domain.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_15 | Pages 82 - 82
7 Nov 2023
Patel V Hayter E Hodgson H Barter R Anakwe R
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Extended patient waiting lists for assessment and treatment are widely reported for planned elective joint replacement surgery. The development of regionally based Elective Orthopaedic Centres, separate from units that provide acute, urgent or trauma care has been suggested as one solution to provide protected capacity and patient pathways. These centres will adopt protocolised care to allow high volume activity and increased day-case care. We report the plan to establish a new elective orthopaedic centre serving a population of 2.4 million people. A census conducted in 2022 identified that 15000 patients were awaiting joint replacement surgery with predictions for further increases in waiting times

The principle of care will be to offer routine primary arthroplasty surgery for low risk (ASA 1 and 2) patients at a new regional centre. Pre-operative assessment and preparation will be undertaken digitally, virtually and/or in person at local centres close to the where patients live. This requires new and integrated pathways and ways of working. Predicting which patients will require perioperative transfusion of blood products is an important safety and quality consideration for new pathways. We reviewed all cases of hip and knee arthroplasty surgery conducted at our centre over a 12-month period and identified pre-operative patient related predictive factors to allow us to predict the need for the perioperative transfusion of blood products.

We examined patient sex, age, pre-operative haemaglobin and platelet count, use of anti-coagulants, weight and body mass index to allow us to construct the Imperial blood transfusion tool.

We have used the results of our study and the transfusion tool to propose the patient pathway for the new regional elective orthopaedic centre which we present.


Bone & Joint Open
Vol. 3, Issue 1 | Pages 42 - 53
14 Jan 2022
Asopa V Sagi A Bishi H Getachew F Afzal I Vyrides Y Sochart D Patel V Kader D

Aims

There is little published on the outcomes after restarting elective orthopaedic procedures following cessation of surgery due to the COVID-19 pandemic. During the pandemic, the reported perioperative mortality in patients who acquired SARS-CoV-2 infection while undergoing elective orthopaedic surgery was 18% to 20%. The aim of this study is to report the surgical outcomes, complications, and risk of developing COVID-19 in 2,316 consecutive patients who underwent elective orthopaedic surgery in the latter part of 2020 and comparing it to the same, pre-pandemic, period in 2019.

Methods

A retrospective service evaluation of patients who underwent elective surgical procedures between 16 June 2020 and 12 December 2020 was undertaken. The number and type of cases, demographic details, American society of Anesthesiologists (ASA) grade, BMI, 30-day readmission rates, mortality, and complications at one- and six-week intervals were obtained and compared with patients who underwent surgery during the same six-month period in 2019.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_10 | Pages 48 - 48
1 Oct 2020
Kayani B Onochie E Patel V Begum F Cuthbert R Ferguson D Bhamra JS Sharma A Bates PD Haddad FS
Full Access

Background

There remains a paucity of clinical studies on the effects of coronavirus on perioperative outcomes, with no existing trials reporting on risk factors associated with increased risk of postoperative mortality in these patients. The objectives of this study were to assess perioperative complications and identify risk factors for increased mortality in patients with coronavirus undergoing surgery.

Methods

This multicentre cohort study included 340 coronavirus negative patients versus 82 coronavirus positive patients undergoing surgical treatment for neck of femur fractures across nine NHS hospitals within Greater London, United Kingdom. Predefined study outcomes relating to patient demographics, fracture configuration, operative treatment, perioperative complications and mortality were recorded by observers using a standardised data collection proforma. Univariate and multivariate analysis were used to identify risk factors associated with increased risk of mortality.


The Bone & Joint Journal
Vol. 96-B, Issue 1 | Pages 122 - 126
1 Jan 2014
Bloch BV Patel V Best AJ

Since the introduction of the National Institute for Health and Care Excellence (NICE) guidelines on thromboprophylaxis and the use of extended thromboprophylaxis with new oral agents, there have been reports of complications arising as a result of their use. We have looked at the incidence of wound complications after the introduction of dabigatran for thromboprophylaxis in our unit.

We investigated the rate of venous thromboembolism and wound leakage in 1728 patients undergoing primary joint replacement, both before and after the introduction of dabigatran, and following its subsequent withdrawal from our unit.

We found that the use of dabigatran led to a significant increase in post-operative wound leakage (20% with dabigatran, 5% with a multimodal regimen; p < 0.001), which also resulted in an increased duration of hospital stay. The rate of thromboembolism in patients receiving dabigatran was higher (1.3%) than in those receiving the multimodal thromboprophylaxis regimen, including low molecular weight heparin as an inpatient and the extended use of aspirin (0.3%, p = 0.047). We have ceased the use of dabigatran for thromboprophylaxis in these patients.

Cite this article: Bone Joint J 2014;96-B:122–6.


The Bone & Joint Journal
Vol. 96-B, Issue 1 | Pages 19 - 23
1 Jan 2014
Sabharwal S Gauher S Kyriacou S Patel V Holloway I Athanasiou T

We evaluated the quality of guidelines on thromboprophylaxis in orthopaedic surgery by examining how they adhere to validated methodological standards in their development. A structured review was performed for guidelines that were published between January 2005 and April 2013 in medical journals or on the Internet. A pre-defined computerised search was used in MEDLINE, Scopus and Google to identify the guidelines. The AGREE II assessment tool was used to evaluate the quality of the guidelines in the study.

Seven international and national guidelines were identified. The overall methodological quality of the individual guidelines was good. ‘Scope and Purpose’ (median score 98% interquartile range (IQR)) 86% to 98%) and ‘Clarity of Presentation’ (median score 90%, IQR 90% to 95%) were the two domains that received the highest scores. ‘Applicability’ (median score 68%, IQR 45% to 75%) and ‘Editorial Independence’ (median score 71%, IQR 68% to 75%) had the lowest scores.

These findings reveal that although the overall methodological quality of guidelines on thromboprophylaxis in orthopaedic surgery is good, domains within their development, such as ‘Applicability’ and ‘Editorial Independence’, need to be improved. Application of the AGREE II instrument by the authors of guidelines may improve the quality of future guidelines and provide increased focus on aspects of methodology used in their development that are not robust.

Cite this article: Bone Joint J 2014;96-B:19–23.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 76 - 76
1 Apr 2012
Srinivas S Patel V Hegarty J Collins I
Full Access

To review blood transfusion practices during elective spinal surgery procedures

Prospective clinical audit

All patients who underwent elective spinal surgery between January 2009 and March 2009.

Crossmatch: Transfusion ratio (C: T ratio); Transfusion index (TI) (Evaluates cost-effective crossmatch). British Haematological society standards are C:T ratio= 2.5:1 and TI>0.5

Data was collected from electronic records of blood bank, pathology system (NOTIS) and review of patient notes. A total of 194 patients underwent elective spinal surgery in our unit. (Cervical spine = 15, Thoracic spine = 3, Vertebroplasty = 10, Lumbar spine = 142, Deformity = 31, other = 8). Of these, 62 patients had 197 blood products crossmatched but only 37 units were used. C:T ratio in lumbar spine surgery was 22:1. However C: T ratio in cervical spine procedures, thoracic spine and deformity correction were 6:1, 11:0 and 4:1 respectively. TI was <0.5 in all procedures except deformity surgery (TI=1).

Over- ordering of blood products is still common in spinal surgery as routine blood transfusion may not be required in most elective procedures. Therefore implementing Electronic Issue (EI) of blood products for elective spinal procedures for non deformity procedures can be a cost effective and safe practice.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 465 - 465
1 Nov 2011
Petrella A Armstrong J Patel V Laz P Rullkoetter P
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Cross-shear has been shown to increase ultra-high molecular weight polyethylene (UHMWPE) wear in pin-on-disk, total knee, total hip, and spinal disc replacement testing. Computer modelling of implant wear holds promise for improving efficiency in the development of new implant designs, but it is desirable to accurately account for the effects of cross-shear in the computational simulation. Several studies have sought to propose a quantitative metric for cross-shear in multidirectional sliding and to correlate average cross-shear intensity with apparent wear rate measured in experiments. The apparent wear rate accounts for the total volume loss from all points on the UHMWPE surface. In principle, if the cross-shear metric correlates with experimental wear rates, it is then possible to predict an estimated wear rate for any arbitrary set of kinematic inputs. UHMWPE wear may then be simulated numerically with some form of Archard’s law.

One limitation of the above approach is that counter-face kinematics are homogenized by the use of a spatially and temporally averaged apparent wear rate. In a sliding contact interface of a joint implant in vivo, the intensity of cross-shear wear may vary with time and location on the surface. To address this variation we have proposed a novel cross-shear metric (x*) and developed a modified form of Archard’s law that is capable to differentiate between unidirectional and multidirectional sliding wear. The wear model and x* have been implemented in an explicit finite element framework (ABAQUS) that is capable of quantifying wear from any number of wear surfaces (e.g., front side, backside, post) with completely general geometry and loading conditions.

Preliminary validation of x* and the wear model have been performed by comparison with data from the open literature. Cross-shear metric x* is easy to compute, exhibits invariance to the choice of kinematic reference frame, and is able to reliably distinguish between similarly shaped sliding paths of different lengths – all improvements compared to cross-shear metrics described elsewhere. The wear model that incorporates x* has shown good agreement with pin-on-disk and cervical disc replacement wear results previously reported. Ongoing research focuses on demonstrating similar validity of the model for cross-shear wear in hip and knee replacements.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 94 - 94
1 May 2011
Blakey C Kamat Y Singh P Dinneen A Vie A Patel V Adhikari A Field R
Full Access

Publication of normal and expected outcome scores is necessary to provide a benchmark for auditing purposes following arthroplasty surgery. We have used the Oxford knee score to monitor the progress of knee replacements undertaken since 1995, the start of our review programme. 4847 Oxford assessments were analysed over an 8 year follow-up period.

The mean pre-operative Oxford knee score was 39.2, all post-operative reviews showed a significant improvement. Patients with a BMI > 40, and the under 50 age group showed early deterioration in outcome scores, returning to pre-operative levels by 5 and 7 years respectively. There was no significant difference in outcome between surgeons performing < 20 knee replacements a year and those performing > 100 / year.

The age of the patient at the time of surgery and the pre-operative body habitus have been identified as factors affecting long term outcome of total knee replacement surgery. Awareness of these factors may assist surgeons in advising patients of their expected outcomes following surgery.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 1 | Pages 72 - 76
1 Jan 2007
Patel V Day A Dinah F Kelly M Bircher M

Specific radiological features identified by Brandser and Marsh were selected for the analysis of acetabular fractures according to the classification of Letournel and Judet. The method employs a binary approach that requires the observer to allocate each radiological feature to one of two groups. The inter- and intra-observer variances were assessed. The presence of articular displacement, marginal impaction, incongruity, intra-articular fragments and osteochondral injuries to the femoral head were analysed by a similar method. These factors were termed ‘modifiers’ and are generally considered when planning operative intervention and, critically, they may influence prognosis.

Six observers independently assessed 30 sets of plain radiographs and CT scans on two separate occasions, 12 weeks apart. They were asked to determine the presence or absence of specific radiological features. This simple binary approach to classification yields an inter- and intra-observer agreement which ranges from moderate to near-perfect (κ = 0.49 to 0.88 and κ = 0.57 to 0.88, respectively). A similar approach to the modifiers yields only slight to fair inter-observer agreement (κ = 0.20 to 0.34) and slight to moderate intra-observer agreement (κ = 0 to 0.55).