1. A method of constricting sciatic nerves of rats was devised which produced lesions resembling macroscopically and electromyographically those of carpal tunnel and related syndromes.

2. The nerves became swollen and hyperaemic proximal and distal to the constriction. The swellings were largely caused by an accumulation of fluid between the axons, but the axons themselves were also increased in size.

3. This accumulation of fluid was an oedema secondary to a partial obstruction of the vasa nervorum.

1. Experimental evidence is advanced to suggest that the effect of the McMurray displacement osteotomy in osteoarthritis of the hip is to diminish the load carried by the head of the femur, firstly by correction of deformity, and secondly by a "pelvic support" action.

2. A review of seventy-five cases has revealed certain important details in selection and operative management. The end-results indicate that the operation, when correctly performed, is successful in relieving pain and diminishing disability.