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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_5 | Pages 5 - 5
23 Apr 2024
Sain B Sidharthan S Naique S
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Introduction

Treatment of non-union in open tibial fractures Gustilo-Anderson(GA)-3A/3B fractures remains a challenging problem. Most of these can be dealt using treatment methods that requires excision of the non-union followed by bone grafting, masquelet technique, or acute shortening. Circular fixators with closed distraction or bone transport also remains a useful option. However, sometimes due to patient specific factors these cannot be used. Recently antibiotic loaded bone substitutes have been increasingly used for repairing infected non-unions. They provide local antibiotic delivery, fill dead space, and act as a bone conductive implant, which is resorted at the end of a few months. We aimed to assess the outcome of percutaneous injection of bone substitute while treating non-union of complex open tibial fractures.

Materials & Methods

Three cases of clinical and radiological stiff tibial non-union requiring further intervention were identified from our major trauma open fracture database. Two GA-3B cases, treated with a circular frame developed fracture-related-infection(FRI) manifesting as local cellulitis, loosened infected wires/pins with raised blood-markers, and one case of GA-3A treated with an intramedullary nail. At the time of removal of metalwork/frame, informed consent was obtained and Cerament-GTM(bone-substitute with gentamicin) was percutaneously injected through a small cortical window using a bone biopsy(Jamshedi needle). All patients were allowed to weight bear as tolerated in a well-fitting air-cast boot and using crutches. They were followed up at 6 weekly intervals with clinical assessment of their symptoms and radiographs. Fracture union was assessed using serial radiographs with healing defined as filling of fracture gap, bridging callus and clinical assessment including return to full painless weight bearing.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_4 | Pages 24 - 24
1 Mar 2021
Sephton B Cruz N Kantharuban S Naique S
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Blood management protocols attempt to reduce blood loss by strategies including autologous blood donation, red cell salvage, normovolaemic haemodilution and haemostatic agents such as tranexamic acid (TXA). TXA usage in particular has become increasingly commonplace with numerous studies demonstrating a significant reduction in peri-operative blood loss and proportion of patients requiring transfusion, without increasing the risk of venous thromboembolism. Tourniquet usage has now become ubiquitous in TKA operations with reported benefits of improved visualization, shorter operative time and decreased intra-operative bleeding. However, its use is not without considerable complications including wounding dehiscence, increased venous thromboembolism, superficial wound infection and skin blistering. It is therefore imperative that we review tourniquet usage in light of ever evolving blood management strategies. The aim of this study was to evaluate the effect of stopping tourniquet usage in primary TKRs, performed by an experienced surgeon, in light of new blood reduction measures, such as a TXA.

A retrospective analysis identified a total of 31 patients who underwent primary TKR without the use of a tourniquet from January 2018 to March 2019. This was compared to an earlier group of patients from the same surgeon undergoing TKR with the use of a tourniquet; dating from July 2016 to November 2017. All surgeries were performed within the same hospital (CXH). Peri-operative factors and outcome measures were collected for analysis.

There was no significant difference in post-operative haemoglobin drop (Tourniquet, 23.1 g/L; No Tourniquet, 24.4 g/: p=0.604) and fall in haematocrit (Tourniquet, 0.082; No Tourniquet, 0.087: p=0.604). Allogenic blood transfusion rates were the same in both groups at 12.9% (2 patients) and blood loss was not found to be significantly different (Tourniquet, 1067ml; No tourniquet, 1058mls). No significant difference was found in operative time (Tourniquet, 103 minutes; No Tourniquet, 111.7 minutes: p=0.152) or length of stay (Tourniquet, 5.5 days; No Tourniquet, 5.2 days: p=0.516). Tranexamic acid usage was not found to be significant (p=1.000). ROM of motion and analgesia requirement was significantly better in the no tourniquet group on one post-operative day out of five analysed (p=0.025, p=00.011). No post-operative thromboembolic events were reported in either group. There was no significant difference in readmission rates (p=0.492) or complications (p=0.238).

The increase in minor complications and potential increased VTE risk with tourniquet usage must be balanced against an improved visual field and reduced blood loss in TKR patients. Our study found no difference in post-operative blood loss and transfusion rates between tourniquet and no tourniquet groups. With ever evolving and improving blood loss management strategies, including the use of TXA, the application of tourniquet may not be needed. Further prospective RCTs are needed to assess the impact of tourniquet usage in light of this.


The Bone & Joint Journal
Vol. 98-B, Issue 3 | Pages 420 - 424
1 Mar 2016
Wordsworth M Lawton G Nathwani D Pearse M Naique S Dodds A Donaldson H Bhattacharya R Jain A Simmons J Hettiaratchy S

Aims

The management of open lower limb fractures in the United Kingdom has evolved over the last ten years with the introduction of major trauma networks (MTNs), the publication of standards of care and the wide acceptance of a combined orthopaedic and plastic surgical approach to management. The aims of this study were to report recent changes in outcome of open tibial fractures following the implementation of these changes.

Patients and Methods

Data on all patients with an open tibial fracture presenting to a major trauma centre between 2011 and 2012 were collected prospectively. The treatment and outcomes of the 65 Gustilo Anderson Grade III B tibial fractures were compared with historical data from the same unit.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_32 | Pages 19 - 19
1 Sep 2013
Rooker J Havard H Palmer A Naique S
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This study aims to assess the impact of re-configuration on provision of trauma care at Hospital A, in particular management of hip fractures.

Originally, Hospitals A and B both provided trauma and elective orthopaedic services. These services are undergoing re-configuration such that Hospital A will provide an elective orthopaedic service while Hospital B will provide an orthopaedic trauma service.

Two time periods, one prior to reconfiguration (time period 1) and one after reconfiguration (time period 2) were identified. All trauma patients presenting to Hospital A requiring surgery during the defined time periods were included.

During time period 1, 197 patients requiring surgery presented to Hospital A, 70 with hip fractures. During time period 2, 149 patients requiring surgery presented to Hospital A, 55 with hip fractures.

As part of the reconfiguration process, there was a reduction in dedicated trauma operating capacity at Hospital A with no equivalent increase in operating capacity at Hospital B.

During time period 1, 70% of patients with hip fractures were operated on within 36 hours, compared to 44% during time period 2.

During the re-configuration process, there was a statistically significant decrease in the percentage of patients with hip fractures meeting the recommended standards of care.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 146 - 146
1 Apr 2005
Kharwadkar N Branfoot T Kent R Naique S
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Objective : The valgus angle of the distal femur determines the axial alignment of limb. It is used to plan the realignment osteotomies in limb reconstruction surgery and to determine the angle of resection of the distal femur in total knee arthroplasty. The objective of this study was to analyse the variation of the valgus angle of the distal femur in a random Caucasian population with osteoarthritic knees presenting for total knee arthroplasty.

Method : A prospective study was undertaken involving a review of pre-operative CT scout films of osteoarthritic knees in 83 consecutive patients (44 males and 39 females; mean age 70.2 years) presented for total knee arthroplasty between May 1999 and October 2002. The valgus angle was calculated from the difference between the anatomical and mechanical axes of femur plotted on CT scanogram films.

Results : Mean valgus angle was 5.4 degrees (range 3.3 to 7.6 degrees) with a standard deviation of 1.1 degrees. Estimated 95% confidence interval of the mean for the population was 3.6 – 7.4 degrees. There were no significant differences for age, gender or laterality of the limb.

Conclusion : The value of mean valgus angle of the distal femur in osteoarthritic knees was found to be significantly lower than the one quoted in the literature in normal disease-free knees. This may have important implications on the preoperative planning of appropriate surgical planes for total knee arthroplasty or corrective osteotomies.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 169 - 169
1 Feb 2003
Naique S Laheri V
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Rigid angular kyphotic deformities of the spine have been corrected by staged anterior and posterior procedures. This paper evaluates the efficacy of single stage transpedicular decancellation, vertebral column mobilization and spinal shortening in the correction of rigid THORACIC kyphotic deformities in adolescent patients.

Between 1993 and 1999, 21 patients with rigid kyphosis underwent deformity correction using the above procedure. The deformity was thoracic in 6 patients, thoraco-lumbar in 14 and lumbar in one patient. This report focuses on 6 patients with thoracic deformity. The etiology in 5 patients was due to tuberculosis while one patient had a congenital anomaly. There were 4 females and 2 male patients. The average age was 12 years. The average kyphosis was 75 degrees (38 – 135 degrees). Of the 6 patients, 2 had preoperative paraplegia. All cases were assessed using CT and MRI scans in addition to plain radiographs. The surgical technique utilized the principle of transpedicular decancellation through a single posterior midline exposure in the prone position. Following complete decancellation of the apical vertebrae, the proximal and distal vertebral column was adequately mobilized to enable spinal shortening along with anterior translation. Segmental spinal instrumentation was used to achieve stable fixation.Intraoperatively, the wake-up test was used to assess the neurological function. This was followed by anterior interbody fusion and posterolateral fusion. At an average follow-up of 36 months, average kyphosis correction was 61% and all cases were adequately fused. Both cases with paraplegia recovered completely. The average loss of correction was 6 degrees. One patient developed hyperlordosis below the corrected level. This was revised by extending the spinal fixation to include the lower levels. In conclusion, the above procedure is used as a last resort for correction of rigid angular deformities. It is a safe but demanding procedure. Spinal column shortening is essential to avoid neurologic compromise and balance the column.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 40 - 41
1 Jan 2003
Naique S Madhav R Pearse M
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31 cases of high-energy proximal tibial fractures were retrospectively analysed. The series included 22 cases of Schatzker VI and 9 cases of proximal tibial extraarticular fractures There were 7 females and 24 males, with average age being 45 years (26–94). There were 12 open fractures (1 Gustilo grade1, 10 grade 3b and one 3c); while 19 cases had Tcherne’s grade 2–3 injury. 4 patients developed compartment syndromes requiring fasciotomy. All fractures were treated with preliminary ligamentotaxis using a unilateral external fixator. In addition, open fractures underwent radical debridement with the one case of 3c requiring vascular reconstruction. CT scan was then done to assess the joint incongruity, anatomy of the fracture, and to aid in decision making. The fractures were then fixed using percutaneous technique and a circular external fixator. Minimal open reduction was resorted to in cases with significant joint depression. In all, 26 cases were managed using percutaneous techniques alone while 5 require minimal open reduction and screw fixation. Bone grafting was done in 6 cases and 11 required a plastics procedure for soft tissue reconstruction. The results were assessed using the radiological Rasmussen’s criteria and the clinically using the IKSS knee score. At a mean follow-up of 31mths, the mean time to metaphyseal union was 18 weeks (6–25 weeks); 28 patients had good to excellent clinical scores, while 3 had a fair result. The radiologic assessment graded 12 cases as excellent and 19 as good. Complications included 2 cases with flap edge necrosis, 2 with severe pin tract sepsis, 1 with proximal DVT and one case with septic arthritis.

We conclude that the above treatment protocol yields promising results, preserving good knee function without prejudicing future need for arthroplasty.


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 3 | Pages 328 - 331
1 Apr 2001
Naique S Laheri VJ

Craniodiaphyseal dysplasia (CDD) is a rare sclerosing bone disorder, the severity of which depends on its phenotypic expression. Hyperostosis can cause progressive foraminal stenosis leading to palsy of cranial nerves, epilepsy and mental retardation. We report the only case of CDD in an adult, with stenosis of the cervical canal leading to quadriparesis as a late complication of hyperostosis, and describe the problems associated with its treatment. Although the syndrome is rare, its pathophysiological and therapeutic considerations may be applicable to the management of stenosis of the spinal canal in other hyperostotic bone disorders.