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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 39 - 39
1 Jul 2022
THE ROLE OF PLATELET-RICH PLASMA (PRP) INTRA-ARTICULAR INJECTIONS IN RESTORING ARTICULAR CARTILAGE OF OSTEOARTHRITIC KNEES: A SYSTEMATIC REVIEW AND META-ANALYSIS
Prodromidis A Charalambous C Moran E Venkatesh R Pandit H
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Abstract

Introduction

This study aimed to assess the effect of PRP on knee articular cartilage content (thickness and/or volume) and establish if there is a correlation between changes in cartilage and clinical outcomes in patients with knee osteoarthritis.

Methodology

A systematic review was performed following the Cochrane methodology. Studies were included if they reported on cartilage content with MRI or Ultrasound before and after the injection. A random-effects model meta-analysis was performed.