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Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 12 - 12
1 Apr 2018
Moharamzadeh D Piarulli G Molisani D Andreoletti G
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Cementless total knee replacement (TKR) is at the present date a controversial topic. Aim of the study was to compare the effect on tibial periprosthetic bone mineral density (BMD) between different implant materials and designs.

During the two-year period between January 2005 and December 2006, we analysed data of 45 patients who underwent consecutively cementless TKR (49 implants) at our Institution for primary osteoarthritis. Data was divided in 2 groups: A) 26 implants with tantalium tibial component (Zimmer NexGen Trabecular MetalTM Monoblock); B) 23 implants with porous titanium tibial component (Lima MultiGenTM). Data was comparable per sex, age, BMI, post-op alignment, post-op KSS > 75, absence of major post-op complications. Standard AP x-rays were taken 4 months post-op and 8 years post-op. In order to quantify the reduction of BDM, we determined using ImageJ (an open source software) the Mean Grey Value (MGV) of a specific area on the 4 months- and 8 yrs-postop AP x-rays.

Group A and Group B had an average MGV variation of, respectively, 11.79% and 10.51%; there was no statistically significant difference between the two groups.

Reduction of BMD in a TKR is known to be a biomechanical response to load and it is conditioned by the alignment of the components and their design. Our study shows that the different materials (porous titanium vs. tantalium), in relation to the different implant design, have a similar effect on the surrounding bone. The overall results show a valid osseointegration in both group of patients.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 13 - 13
1 Apr 2018
Moharamzadeh D Molisani D Piarulli G Noto G Andreoletti G
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Aim of the study was to analyse the modifications of the pre-op and post-op femoral off-set after cementless total hip replacement.

During an 18-month period, from January 2015 to June 2016, we retrospectively analysed data of 79 (n = 81 hips) patients (M:F = 31:48), with an average age of 70.38 yrs ± 10.05, who consecutively affered to our Department and underwent cementless total hip replacement for primary osteoarthritis with Pinnacle GriptionTM cup and CorailTM stem (Depuy). All cases of infections and revision surgery were excluded. Inclusion criteria: postero-lateral approach, 2 dedicated surgeons. All patients were clinically and radiographically evaluated at 4-months and 1-year postop. Preop and postop femoral off-set were calculated using Impax Agfa software.

Average preop HHS was 46.7 ± 7.7; at 4-months post-op 86.4 ± 5.7; at 1-year post-op 90.0 ± 5 (the improvement had a statistically significant p-value). There was no statistical significant difference between the preop and postop off-set values obtained (t-student test). In 38 (46.9%) hips we increased the femoral off-set and we analysed using χ₂-test if there was a correlation with hip pain, HHS and dislocation. There was no statistical significance.

Our overall results show good and excellent clinical results at 1 year follow-up in cementless total hip replacement. We believe that our pre-op digital planning of the implant and the offset obtained is a crucial step in determining these results.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 526 - 526
1 Oct 2010
Moya L Buly R Henn F Kelly B Ma Y Molisani D
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Introduction: Femoroacetabular impingement (FAI) is one of the main causes of hip osteoarthritis. Femoral retroversion has been reported as a cause of FAI and it is well established that a retroverted femur produces hip pain and alterations in the external and internal rotation balance. However, no studies of femoral retroversion in patients with FAI have been reported. Furthermore, since the lack of internal rotation is a common feature in patients with FAI, it could be possible that femoral version abnormalities are present in these patients. The purpose of this study is to describe the femoral version in a group of patients with FAI and to assess its relation in the development of hip osteoarthritis.

Methods: The history, x-rays and hip CT scans of 142 patients with FAI were reviewed. All patients presented persistent hip pain and were evaluated clinically between January 2006 and July 2008. We defined FAI when at least one of the following features were present:

an abnormal alpha angle (> 49°) measured on the elongated femoral neck x-ray,

a positive cross-over sign or pro-trusio acetabuli in the AP pelvis x-ray,

the presence of diminished anteversion in the femur (< 10°) or a retroverted femur (< 0°) in the CT scan, associated with a positive hip impingement test and lack of internal rotation at 90 degrees of flexion.

We documented the type of FAI, the presence of acetabular dysplasia, coxa valga, coxa vara and the femoral version measured on the CT scan. The degree of osteoarthritis of the hip using the Tönnis classification was documented as well.

Results: Two hundred and sixty-five FAI hips from 142 patients (73 females and 69 males) were analyzed. The average age was 36.7 years. The mean femoral version was 11.4 ° (−14.1° to 47°). We found 43 hips (16.6%) of the femora were retroverted and 133 hips (50%) had either diminished anteversion (< 10°) or were retroverted. In 12 hips (0.05%) the only cause of FAI was the presence of a diminished anteversion or retroverted femur. The statistical analysis using the generalized estimating equations method including the right and left hips, shown that among these six predictors, both femoral retroversion (p=0.046) and coxa vara (p< 0.001) were statistically significant for the presence of osteoarthritis.

Conclusion: The presence of a retroverted femur seems to be a cofactor in the development of hip osteoarthritis in patients with FAI. The orthopedic surgeons should be aware of the high frequency of femoral retroversion when evaluating patients with hip impingement, in order to make the right diagnosis and treatment. It might be possible that this association between FAI and femoral retroversion is due to a common hip disease during skeletal maturation (i.e. SCFE) leading to two anatomical alterations at the proximal femur: reduced head-neck offset and retroverted femur.