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Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_14 | Pages 67 - 67
1 Nov 2018
Bouaicha S Ernstbrunner L Jud L Meyer D Snedeker J Bachmann E
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Tear pattern and tendon involvement are risk factors for the development of a pseudoparalytic shoulder. However, some patients have similar tendon involvement but significantly different active forward flexion. In these cases, it remains unclear why some patients suffer from pseudoparalysis and others with the same tear pattern show good active range of motion. Moment arms (MA) and force vectors of the RC and the deltoid muscle play an important role in the muscular equilibrium to stabilize the glenohumeral joint. Biomechanical and clinical analyses were conducted calculating different MA-ratios of the RC and the deltoid muscle using computer rigid body simulation and a retrospective radiographic investigation of two cohorts with and without pseudoparalysis and massive RC tears. Idealized MAs were represented by two spheres concentric to the joints centre of rotation either spanning to the humeral head or deltoid origin of the acromion. Individual ratios of the RC /deltoid MAs on antero-posterior radiographs using the newly introduced Shoulder Abduction Moment (SAM) Index was compared between the pseudoparalytic and non-pseudoparalytic patients.

Decrease of RC activity and improved glenohumeral stability (+14%) was found in simulations for MA ratios with larger diameters of the humeral head which also were consequently beneficial for the (remaining) RC. Clinical investigation of the MA-ratio showed significant risk of having pseudoparalysis in patients with massive tears and a SAM Index <0.77 (OR=11). The SAM index, representing individual biomechanical characteristics of shoulder morphology has an impact on the presence or absence of pseudoparalysis in shoulders with massive RC tears.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 380 - 380
1 Sep 2012
Meyer D Snedeker J Koch P Weinert-Aplin R Farshad M
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Introduction

ACL reconstruction using hamstring tendons has gained general acceptance. However, it has been recommended to seek a tight fit of the tendon in the bone canal in order to provide circumferential contact and healing of the graft, and to prevent secondary tunnel widening. Recent findings show, that the graft dynamically adapts to pressure in the canal resulting in a potentially loose graft-bone contact. It was the goal of this study to understand the viscoelastic behaviour of hamstring grafts under pressure and to develop a new method for tendon pre-conditioning to reduce the graft volume before implantation, in order to reduce the necessary bone canal diameter to accommodate the same graft.

Material and Methods

Flexor digitorum tendons of calf and extensor digitorum tendons of adult sheep were identified to be suitable as ACL grafts substitutes for human hamstring tendons in vitro. The effect of different compression forces on dimensions and weight of the grafts were determined. Further, different strain rates (1mm/min vs 10mm/min), compression methods (steady compression vs. creep) and different compression durations(1, 5, 10min) were tested to identify the most effective combination to reduce graft size by preserving its macroscopic structure.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 125 - 125
1 Sep 2012
Gerber C Meyer D Nuss K Farshad M
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Introduction

Following tear of its tendon, the muscle undergoes retraction, atrophy and fatty infiltration. These changes are inevitable and considered irreversible and limit the potential of successful repair of musculotendinous units. It was the purpose of this study to test the hypothesis that administration of anabolic steroids can prevent these muscular changes following experimental supraspinatus tendon release in the rabbit.

Methods

The supraspinatus tendon was experimentally released in 20 New Zealand rabbits. Musculotendinous retraction was monitored over a period of 6 weeks. The seven animals in group I had no additional intervention, six animals in group II had local and seven animals in group III had systemic administration of nandrolone deconate during six weeks of retraction. At the time of sacrifice, in-vivo muscle performance as well as radiologic and histologic muscle changes were investigated.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 132 - 132
1 May 2011
Farshad M Gerber C Snedeker J Meyer D
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Introduction: Additional tendon length is occasionally needed for the surgical reattachment of retracted tendons and for lengthening of intact but contracted tendons. To achieve additional length with the known techniques such as the z-plasty, the tendon needs to be cut through entirely and loses its continuity. The purpose of this study was to develop a new method for tendon lengthening, where continuity is preserved and a high amount of additional length is achievable.

Methods: Calf Achilles tendons (n=35) were harvested immediately after slaughter and 5 tendons were assigned to groups I to VII. Angles of 60° (group I and IV), 45° (group II and V) and 30° (group III and VI) were cut. In group IV to VI mattress suture stitches were made along the cutting lines. The mean length increase of the helical cuts was used to define the intended length of group VII, where a z-plasty was performed. Maximal tensile force (Fmax) and additional achieved lengthening at Fmax (LFmax) were determined for each tendon using a materials testing machine. Data were statistically analyzed using ANOVA for inter-group differences and Spearman-correlation for cut angle to additional length relations at a significance level of p< 0.05.

Results: Tendons which were cut helically and sutured (group IV to VI) could achieve higher Fmax than the helically cut tendons without suturing (group I to III). The length and tensile force could be partially controlled by choice of the angle of the helical cut; In the groups for which the cut tendons were not sutured, LFmax was negatively correlated to the cut angle (r=−0.66, p=0.010) and positively correlated to the Fmax (r=0.72, p=0.003). If the helical cut tendons were sutured, there was no correlation of LFmax and cut angle (r=−0.01, p=0.96), but strong positive correlation of Fmax and cut angle (r=0.89, p< 0.0001). Helical cut tendon could achieve higher amount of additional length and tensile strength than tendons lengthened using z-plasty; in group VII, a LFmax of 72%±10% was achieved by a Fmax of 70N±15N. Other than in groups III and IV, where the cut angle was 30°, resulting in 179%±80% and 113%±10%, respectively, significant higher tensile force capacities (from a minimum of 80N±54N in group II to maximally 222N±62N in group IV) was achieved.

Discussion: Helical cutting of tendons allows lengthening tendons to an amount not possible with conventional methods. The lengthened coil-shaped tendon remains in continuity and has the potential to withstand considerable loads also without additional suture reinforcement. The behavior of the helical cut tendon in vivo is not known. However, the preservation of continuity might be favorable not only in regard to high tensile forces but also to healing.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 64 - 64
1 Mar 2009
Leunig M Mladenov K Jamali A Meyer D Martinez A Beck M Ganz R
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Background: Acetabular retroversion has been proposed to contribute to the development of osteoarthritis of the hip. For the diagnosis of this condition, conventional AP pelvic radiographs may represent a reliable, easily available diagnostic modality as they can be obtained with a reproducible technique allowing the anterior and posterior acetabular rims to be visible for assessment. This study was designed to

establish a method to directly quantify anatomic acetabular version on AP pelvic radiographs and to

determine the validity of the radiographic “cross-over-sign” to detect acetabular retroversion.

Methods: Using 43 desiccated pelves (86 acetabuli) the anatomic acetabular versions were measured at three different transverse planes (cranially, centrally and caudally). From these pelves, standardized AP pelvic radiographs were obtained. To directly measure central acetabular version (AV), a modified radiographic method is introduced for the use of AP pelvic radiographs. Moreover, the validity of the radiographic “cross-over-sign” to detect cranial acetabular retroversion was determined.

Results: The mean central and caudal anatomic AV were approximately 20°, the mean cranial AV was 8°. Cranial retroversion (AV < 0°) was present in 19 of 86 hips (22%). A linear correlation was found between the central and cranial AV. Below 10° of central AV, all acetabuli were cranially retroverted. Between 10° and 20°, 30% of the acetabuli were cranially retroverted and above 20°, only one of 45 acetabuli was cranially retroverted. The radiographic measurement of the central AV (20.3° ± 6.5) correlated strongly with the anatomic AV (20.1° ± 6.4). The sensitivity of the ‘cross-over-sign’ to detect an cranial acetabular anteversion of less than 4° was 96%, its specificity 95%, and the positive predictive and negative predictive values 90% and 98%, respectively.

Conclusions: The cranial AV is on average 12° lower than the central AV, with the latter directly measurable from AP pelvic radiographs. A central AV of less than 10° was associated with cranial retroversion. The presence of a positive ‘cross-over-sign’ is a highly reliable indicator of cranial AV of < 4°.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 122 - 122
1 Mar 2009
Zumstein M Meyer D Frey E von Rechenberg B Hoppeler H Jost B Gerber C
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INTRODUCTION: Chronic experimental rotator cuff tears are associated with muscle retraction, atrophy, fatty infiltration, a pronounced change in the pennation angle of the muscle and consequent shortening of muscle fibres. It was the purpose of this investigation to study whether slow, continuous elongation of the musculotendinous unit can revert the pennation angle and elongate the shortened muscle fibres.

MATERIAL AND METHODS: The infraspinatus tendons of twelve sheep were released. After retraction of the tenotomised musculotendinous unit, the infra-spinatus was elongated one mm per day using a new elongation-apparatus. After restoring the approximate original length, the tendon was repaired back. Muscular architecture (retraction and pennation angle), fatty infiltration (in Hounsfield units=HU) and muscular cross sectional area (in % of the mean control side) were analyzed at start, at the time before elongation, at the time of repair and six and eighteen weeks thereafter.

RESULTS: In four sheep the elongation failed technically. In the other eight sheep, elongation could be achieved as planned. After retraction of 29mm ± 6 mm after 16 weeks (14% of original length, p=0.008), the mean traction time was 24 days ± 6 days with a mean traction distance of 19 mm ± 4 mm. At sacrifice the mean pennation angle increased in the failed sheep from 30° ± 6° up to 55° ± 14° (p=0.035). In those sheep in which traction was applied, the mean pennation angle was not different to the control side (29.8° ± 7.5° vs. 30° ± 6°, p=0.575). Compared to preoperative, there was a significant increase in fatty infiltration (36 HU, p=0.0001) and decrease of the muscular cross sectional area of 43 % (range 21% to 67%, p=0.0001) at 4 months. In the sheep in which traction could be achieved, fatty infiltration remain unchanged (36 HU ± 6 HU vs 38 HU ± 4 HU, p=0.438) and atrophy decreased by 22% (range 10% to 33%) after 6 weeks of continuous traction (p=0.008).

CONCLUSION: Continuous experimental elongation of a retracted musculotendinous unit is technically feasible and might lead to recovery of the muscle architecture, partial reversibility of atrophy and, arrest of progression of fatty infiltration.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 63 - 64
1 Mar 2009
Kalberer F Sierra R Madan S Meyer D Ganz R Leunig M
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Background: Femoroacetabular Impingement is now considered a prearthritic hip mechanism. It frequently occurs in patients with subtle anatomic abnormalities of the acetabulum, “acetabular retroversion”, which is often difficult to detect on standart xrays. Early diagnosis is of utmost importance as surgical intervention in early stages can most likely halt progression of disease. The objective of this study was to assess wether an easily visible anatomic landmark on an anteroposterior (AP) pelvic xray can be used to screen patients with acetabular retroversion.

Methods: The AP pelvic xrays of 1010 patients who were seen at the autors’ institution for a painful hip were reviewed over a 16 year period. Those xrays that did not meet standardized criteria were excluded leaving 149 AP radiographs (298 hips) for analysis. The ‘crossover sign’ (COS), indicative of acetabular retroversion, was recorded for each hip. An easily visible landmark, the prominence of ischial spine (PRIS) into the true pelvis was also recorded and measured. Interobserver and intraobserver variability was assessed.

Results: The presence of the PRIS as diagnostic of acetabular retroversion showed a sensitivity of 91% (95%CI 0.85 to 0.95), a specifity of 98% (95% CI 0.94 to 1.00), a positive predictive value of 98% (95%CI 0.94 to 1.00), a negativ predictive value of 92% (95% CI 0.87 to 0.96). There was good and very good intraobserver and interobserver reliability for measurements of the COS and PRIS, respectively.

Conclusion: There was excellent sensitivity and positive predictive value of the PRIS as a radiographic marker of acetabular retroversion. The rims of the anterior and posterior walls are sometimes not clearly visible, and even if they are, their translation into a reliable interpretation of acetabular retroversion is difficult. The PRIS sign appears as a good visible prominence on the AP radiographs which can’t be easily confused.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 293 - 293
1 Jul 2008
MEYER D HOPPELER H GERBER C
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Purpose of the study: Muscles contract after a full thickness tear their tendon. The muscle then undergoes atrophy and fatty degeneration. These changes produce effects well described by histology, computed tomography and magnetic resonance imaging (MRI). To date however, the correlation of this process with the future conractile force of the muscle and the prognosis after cuff repain has been poorly understood.

Material and methods: Thirteen patients with a full thickness tear of the supraspinatus muscle were treated surgically by cuff suture. The shoulders were examined clinically and MRI. During the operation, the supra-scapular nerve was stimulated with a supramaximal voltage to obtain maximal muscle contraction which was measured. Biopsy specimens of the supraspinatus were taken before and after surgical repair in order to determine whether muscle activity during stimulation have any histological impact. The intraoperative measurements were compared with the MRI findings and the physical examination performed preoperative and at six weeks, six months and twelve months after surgery.

Results: Maximal force of the supraspinatus muscle was 200N, which is greater than the force of a direct suture repair. The maximal force was clearly correlated with muscle atrophy and fatty degeneration: by surface area, force was 12N/cm2 for Goutallier grade 3 and 42 N/m2 for grade 0. Five of the thirteen repairs ended with a secondary tear, the muscle in four of the five patients was among the six strongest muscles. The fifth case was the weakest muscle of all. The histological study revealed a larger quantity of lipofuchin in the muscle with atrophy and a change in the fiber structure. Analysis of the results did not demonstrate any lesions caused by the tension during the operation. MRI demonstrated one case of repair without secondary tear, the fatty infiltration had not improved and the atrophy only partially. In muscles with secondary tears, atrophy and fatty degeneration progressed significantly.

Discussion and conclusion: There is a risk of rupture of the supraspinatus tendon in the event of muscle atrophy but also for good quality muscle. The capacity of a muscle to develop force strongly depends on the state of atrophy and fatty degeneration. Atrophy can regress after reconstruction without secondary tear, but fatty degeneration is irreversible.