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The Bone & Joint Journal
Vol. 100-B, Issue 12 | Pages 1542 - 1550
1 Dec 2018
Diagnostic accuracy of serum inflammatory markers in late fracture-related infection
van den Kieboom J Bosch P J. Plate JD A. IJpma FF Kuehl R McNally MA Metsemakers W M. Govaert GA
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Aims

To assess the diagnostic value of C-reactive protein (CRP), leucocyte count (LC), and erythrocyte sedimentation rate (ESR) in late fracture-related infection (FRI).

Materials and Methods

PubMed, Embase, and Cochrane databases were searched focusing on the diagnostic value of CRP, LC, and ESR in late FRI. Sensitivity and specificity combinations were extracted for each marker. Average estimates were obtained using bivariate mixed effects models.