In an initial randomised controlled trial (RCT) we segregated 180 patients to one of two knee positions following total knee replacement (TKR): six hours of knee flexion using either a jig or knee extension. Outcome measures included post-operative blood loss, fall in haemoglobin, blood transfusion requirements, knee range of movement, limb swelling and functional scores. A second RCT consisted of 420 TKR patients randomised to one of three post-operative knee positions: flexion for three or six hours post-operatively, or knee extension.

Positioning of the knee in flexion for six hours immediately after surgery significantly reduced blood loss (p = 0.002). There were no significant differences in post-operative range of movement, swelling, pain or outcome scores between the various knee positions in either study. Post-operative knee flexion may offer a simple and cost-effective way to reduce blood loss and transfusion requirements following TKR.

We also report a cautionary note regarding the potential risks of prolonged knee flexion for more than six hours observed during clinical practice in the intervening period between the two trials, with 14 of 289 patients (4.7%) reporting lower limb sensory neuropathy at their three-month review.

Cite this article: Bone Joint J 2014;96-B:201–9.

Introduction: A critical determinant of early dislocation following total hip arthroplasty (THA) is correct positioning of the acetabular component. This challenging aspect of THA has not been lessened by the introduction of more minimally invasive techniques. In this paper we introduce a simple and reproducible technique, which uses the transverse acetabular ligament (TAL) to determine cup orientation. We have used this technique as the sole method of cup orientation in our last 1000 consecutive primary total hips.

Methods: One thousand consecutive patients were studied in order to determine the prevalence of early dislocation (within 3 months) following acetabular component placement determined by reference to the transverse ace-tabular ligament. All patients underwent primary total hip arthroplasty via a posterolateral approach with a posterior repair.

Results: At a minimum follow-up of 9 months (range 9–39 months) 6 of the 1000 hips (0.6%) had dislocated.

Conclusion: Although multiple factors are known to contribute to this rate correct placement of the acetabular component is critical. As our results compare favourably with other published series where a posterior repair has been performed by extrapolation we feel that that the TAL does provide an acceptable method of determining cup orientation. The fact that it is independent of patient position on the table and is easy to locate with a minimally invasive approach makes it an attractive method.

Introduction: Blood loss is a major concern following total knee arthroplasty (TKA) frequently resulting in blood transfusions postoperatively. Various strategies exist to reduce blood loss and allogenic transfusion requirements. This study investigates the effect of immediate postoperative flexion on blood loss and transfusion requirements following TKA.

Methods: 180 consented patients undergoing primary TKA by a single surgeon were enrolled into a prospective randomised controlled study. 90 patients were randomised to have the operated knee nursed in extension postoperatively, and 90 patients to have the knee nursed in flexion for six hours postoperatively. Both groups followed a strict transfusion protocol. Data collected included calculated pre- and postoperative haemoglobin and haematocrit which was used to calculate total blood loss. Units transfused and postoperative complication rates were also recorded.

Results: There was no significant difference in demographics or factors predisposing to bleeding between the groups. The mean total blood loss was 1841mls for those in the extension group compared with 1587mls in the flexion group (p=0.02). The mean number of units transfused in the extension group was 0.78 units/patient compared with 0.36 units/patient in the flexion group (p=0.004). There was no significant difference in pain scores between the groups (p= 0.62).

Conclusion: This study shows that the use of immediate postoperative flexion significantly reduces calculated total blood loss and transfusion rates following TKA.

Patients and Methods: One hundred and fifty patients with pre-operative haemoglobin levels of 13.0g/dl or less were enrolled into a randomised controlled trial comparing the blood saving effect of intravenous tranexamic acid and topical fibrin spray on blood loss following primary total knee arthroplasty.

Those randomly assigned to the Tranexamic Acid group received 500mg intravenously five minutes prior to tourniquet deflation and a repeat dose three hours later. Those assigned to the Topical Fibrin Spray group received 10mls of the combined product intra-operatively. Those in the control group received no pharmacological intervention.

Results: There was a significant saving in total calculated blood loss for those in the topical fibrin spray group (p=0.016) and the tranexamic acid group (0.041) compared with the control group with losses of 1190mls, 1225mls and 1415mls respectively. The increased reduction in blood loss in the topical fibrin spray group was not significantly different to that in the tranexamic acid group (p=0.72).

Between April 1992 and July 2005, 310 posterior lip augmentation devices were used for the treatment of recurrent dislocation of the hip in 307 patients who had received primary total hip replacements (THRs) using Charnley/Charnley Elite components with a cemented acetabulum. The mean number of dislocations before stabilisation with the device was five (1 to 16) with a mean time to this intervention from the first dislocation of 3.8 years (0 days to 22.5 years). The mean age of the patients at this reconstruction was 75.4 years (39 to 96).

A retrospective clinical and radiological review was carried out at a mean follow-up of six years and nine months (4.4 months to 13 years and 7 months). Of the 307 patients, 53 had died at the time of the latest review, with a functioning THR and with the posterior lip augmentation device in situ. There were four revisions (1.3%), one for pain, two for deep infection and one for loosening of the acetabular component. Radiolucent lines around the acetabular component increased in only six cases after insertion of the device which was successful in eliminating instability in 302 patients, with only five further dislocations (1.6%) occurring after its insertion.

We performed a randomised, controlled trial involving 150 patients with a pre-operative level of haemoglobin of 13.0 g/dl or less, to compare the effect of either topical fibrin spray or intravenous tranexamic acid on blood loss after total knee replacement.

A total of 50 patients in the topical fibrin spray group had 10 ml of the reconstituted product applied intra-operatively to the operation site. The 50 patients in the tranexamic acid group received 500 mg of tranexamic acid intravenously five minutes before deflation of the tourniquet and a repeat dose three hours later, and a control group of 50 patients received no pharmacological intervention.

There was a significant reduction in the total calculated blood loss for those in the topical fibrin spray group (p = 0.016) and tranexamic acid group (p = 0.041) compared with the control group, with mean losses of 1190 ml (708 to 2067), 1225 ml (580 to 2027), and 1415 ml (801 to 2319), respectively. The reduction in blood loss in the topical fibrin spray group was not significantly different from that achieved in the tranexamic acid group (p = 0.72).

Ensuring the accuracy of the intra-operative orientation of the acetabular component during a total hip replacement can be difficult. In this paper we introduce a reproducible technique using the transverse acetabular ligament to determine the anteversion of the acetabular component. We have found that this ligament can be identified in virtually every hip undergoing primary surgery. We describe an intra-operative grading system for the appearance of the ligament. This technique has been used in 1000 consecutive cases. During a minimum follow-up of eight months the dislocation rate was 0.6%. This confirms our hypothesis that the transverse acetabular ligament can be used to determine the position of the acetabular component. The method has been used in both conventional and minimally-invasive approaches.

Isolated patellofemoral osteoarthritis has been reported to occur in approximately 5% of patients with gon-arthrosis of the knee. A number of options are available for the surgical management of these individuals. We reported the short-term outcomes on thirty three patients (33 knees) with isolated patellofemoral osteoarthritis who underwent LCS total knee arthroplasty (TKA) without resurfacing who had been operated on between 1996 – 1999¹.

Barrack et al² in 2001 reported on the incidence of anterior knee pain in two groups of TKA patients, one with patella resurfacing and one without. They reported an increase incidence of anterior knee pain in both groups.

We now report the longer-term outcomes with an average follow-up of 80.2months (range 54–94 months). At latest review, 9 patients experienced night time pain, all describing it as improved from their preoperative level. Twelve patients walked with the use of a walking aid, compared with 21 preoperatively. Disease specific scores at latest review showed improved outcome measures at latest review.

We also report our outcomes in an additional fifty-five patients (59 knees) with isolated patellofemoral osteoarthritis who were treated between 1999–2004 receiving an LCS total knee arthroplasty without patellar resurfacing. Our preliminary findings suggest that this technique continues to be an option in the management of the older patient with isolated patellofemoral osteoarthritis.