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The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 3 | Pages 308 - 314
1 Mar 2012
Ito H Tanino H Yamanaka Y Nakamura T Takahashi D Minami A Matsuno T

We have previously described the mid- to long-term results of conventional simple varus intertrochanteric osteotomy for osteonecrosis of the femoral head, showing that 19 of the 26 hips had good or excellent results. We extended the follow-up to a mean of 18.1 years (10.5 to 26) including a total of 34 hips in 28 patients, with a mean age at surgery of 33 years (19 to 53). There were 18 men and ten women and 25 hips (74%) had a satisfactory result with a Harris hip score ≥ 80. In all, six hips needed total hip replacement (THR) or hemiarthroplasty. The collapse of the femoral head or narrowing of the joint space was found to have progressed in nine hips (26%). Leg shortening after osteotomy was a mean of 19 mm (8 to 36). With conversion to THR or hemiarthroplasty as the endpoint, the ten-year survival rate was 88.2% (95% confidence interval (CI) 82.7 to 93.7) and the 20-year survival rate was 79.7% (95% CI 72.1 to 87.3); four hips were converted at ten years and other two hips were converted at 20 years.

Shortening of the leg after osteotomy remains a concern; however, the conventional varus half-wedge osteotomy provides favourable long-term results in hips with less than two-thirds of the medial part of the femoral head affected by necrotic bone and with normal bone superolaterally.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 6 | Pages 726 - 731
1 Jun 2011
Ito H Tanino H Yamanaka Y Nakamura T Minami A Matsuno T

We report the mid- to long-term (mean 20.3 years, 10 to 32.5) results of the Chiari pelvic osteotomy in patients with pre- to advanced stage osteoarthritis in dysplastic hips. We followed 163 Japanese patients (173 hips) with a mean age at surgery of 20 years (9 to 54). Overall, 124 hips (72%) had satisfactory results, with Harris hip scores ≥ 80. Satisfactory results were seen in 105 of 134 hips with pre- or early osteoarthritis (78%) and 19 of 39 hips with advanced osteoarthritis (49%). A total of 15 hips (9%) underwent a total hip replacement (THR) with a mean interval between osteotomy and THR of 16.4 years. With conversion to THR as the endpoint, the 30-year survival rate was 85.9% (95% confidence interval 82.3 to 89.5). It was 91.8% for patients with pre- or early osteoarthritis and 43.6% for those with advanced osteoarthritis (p < 0.001).

We now perform the Chiari osteotomy for patients with dysplastic hips showing poor joint congruency and who prefer a joint-conserving procedure to THR.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 178 - 178
1 Mar 2008
Nakamura T Ito H Atsuta Y Tanino H Nishimura I Shimizu R Ishida T Mitamura Y Matsuno T
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Thigh pain appears often after THA used of the cement-less femoral components, but the appearance mechanism of thigh pain does not have been elucidated. As one factor of manifestation of thigh pain, it has been guessed that the pressure from the inside of medullary cavity of bone by the stem. The purpose of this study is confirming whether the flexor reflex is caused, by using the femur of a rabbit that applied the pressure from the inside of medullary cavity of bone.

Japanese white rabbits with weight of about 3kg were used. Evaluation of the appearance of the pain by the pressure was performed by measurement of the hind leg flexor activity produced by the flexor reflex. After confirming that appearance of the muscles activity by the pain reflex from adding the pain stimulus to the hind leg skin of rabbits, we loaded of the pressure into the inside of medullary cavity of bone and observed whether the muscles activity appears. As the laboratory animals model, we prepared two kinds of rabbits by the difference in the amount of reaming. And we tested how the differences show up between these two kinds of rabbits.

In the rabbits with few amounts of reaming, the flexor reflex appeared in low pressure. But, in the rabbits with many amounts of reaming, the flexor reflex did not appear in high pressure, either.

It is known that the somatic sensory nerves are distributed in the bone, and it is known that the sensory nerve ends exist in the medullary cavity of bone. It was suggested that the pain is induced, when the sensory nerve ends remained in the inside of medullary cavity of bone and the pressure in whicha reaction is possible was carried out there.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 169 - 169
1 Mar 2008
Ito H Matsuno T Nakamura T Minami A
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We evaluated intermediate-term results of primary cementless Omniflex prostheses.

Forty-nine patients (57 hips) with a mean age of 44 years were observed for an average of 8.6 years.

These results were inferior to those using other recent cementless total hip systems. The increasing prevalence of loosening and osteolysis with time are problems related to this Omniflex femoral component. Although the implant design is unique, the authors no longer use this system.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 172 - 172
1 Mar 2008
Yagihashi K Nishimura I Ishida T Ito H Tanino H Nakamura T Matsuno T Mitamura Y
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Prosthetic impingement after THA is to different for the angle and shape of the implant. Purpose of this study is examine the range of motion(ROM) on a computer when angle and shape of the implant are changed.

The 3D implant models were created on a computer. The angle was measured in the flexion, extension, adduction direction byevery 0.1 degrees. There are three kinds of acetabular abduction angle, two kinds of acetabular anteversion angle and two kinds of femoral anteversion angle. There are three kinds of the radius of neck and the neck shaft angle. All 324 patterns of the above model were measured.

When the radius of neck decreased, the ROM increased in all cases. When the neck shaft angle decreased, the ROM increased by almost all cases. When the acetabular anteversion angle increased, the ROM of flexion direction increased and adduction direction decreased, and as for the extension direction, all the factors had influenced the change in the ROM. When the acetabular angle increased, the ROM of the extension direction increased and the flexion directions decreased. As for adduction direction, femoral anteversion angle, acetabular anteversion angles, and the radius of neck had influenced the ROM. When the femoral anteversion angle increased, the ROM of flexion direction increased and extension, adduction direction decreased.

The clinical ROM is affected by the impingement of non-implant and the strain of the soft tissue. Therefore, It’ s considered that the clinical ROM is smaller than the ROM which was investigated in this study in many cases. When the radius of neck and the neck shaft angle decrease, the increase of the ROM expected. However the radius of the neck should not be decreased too much to avoid the decrease of the neck strength.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 3 | Pages 306 - 309
1 Mar 2005
Ito H Matsuno T Minami A

We present the medium-term results of hybrid total hip arthroplasties using pre-coated stems with a second-generation cementing technique. The 128 hips in 111 patients (18 men and 93 women) were followed up at a mean of 11 years after surgery. The mean age at the time of surgery was 61 years. Both components of one hip were removed at ten months after surgery for infection. None of the other 127 femoral components showed possible, probable, or definite loosening at the most recent follow-up. Five acetabular components were revised for aseptic loosening, recurrent dislocation, or displacement of the polyethylene liner from the metal shell. The mean Harris hip score at follow-up was 84 points. A pre-coated femoral component with a second-generation cementing technique provides good clinical function and survival in the medium term.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 398 - 398
1 Apr 2004
Ito H Minami A Matsuno T Tanino H Omizu N Yuhta T
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Introduction: This study evaluated the sphericity of bearing surfaces in total hip arthroplasty.

Methods: All the prosthetic metal femoral heads and the UHMWPE liners evaluated in this study were obtained straight from manufacturers (DePuy Johnson and Johnson, Howmedica Osteonics, Kyocera, Smith and Nephew, Zimmer). Out-of-roundness was assessed as an indicator representing sphericity. A total of 50 femoral heads and 22 UHMWPE liners were evaluated in 1995. Out-of-roundness of ball bearings were measured for the control study. A total of 43 femoral heads and 40 UHMWPE liners were evaluated in 1999 and 2000.

Results: The out-of-roundness of the femoral heads and the UHMWPE liners were significantly inferior to those of ball bearings. The out-of-roundness of the UHMWPE liners was significantly inferior to that of the femoral heads. The out-of-roundness of the femoral head on the sagittal plane was significantly inferior to that on the transverse plane. Several significant differences were found among different manufacturers. Overall, the out-of-roundness of the femoral head on the sagittal plane and UHMWPE liners had improved significantly in 1999/2000 compared to that in 1995.

Discussion: We previously reported that UHMWPE wear in poor out-of-roundness coupling (femoral head: 9.5 μm, socket: 36 μm) was 148% greater compared to those in good out-of-roundness coupling (femoral head: 0.5 μm, socket: 0.6 μm) at 1 million cycle experiments (J Arthroplasty 15:332, 2000). Some prosthetic femoral heads indicated more than 9.5 μm out-of-roundness in the present study, and these femoral heads with poor sphericity might be unfavorable to wear if implanted. We consider that sphericity of UHMWPE liners should be also improved to reduce initial UHMWPE wear. The sphericity of bearing surfaces can be improved by appropriate changes in manufacturing technique. Further improvement is desirable, since this is expected to prolong the functional performance of the prosthesis after total hip arthroplasty.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 410 - 410
1 Apr 2004
Omizu N Ito H Tanino H Matsuno T
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The use of prostheses with porous surfaces in cementless total hip arthroplasty now predominates. Beads are popular for use as a porous coating, but their mechanical strength may be insufficient because of displacement of some of the beads from the coating. In this study, we propose a new porous surface, created by making direct holes in the metal surface using a YAG laser. A titanium-alloy (Ti-6Al-4V) rod was used. A Bead-type prosthesis was made by diffusion bonding pure titanium beads to the rod; it was 5 mm in diameter and 35% in porosity. A Laser type was made by directly creating holes in the same rod surface using a YAG laser; it was 5 mm in diameter and 33.7% in porosity. Both implants were evaluated in vivo using the hemitranscortical cylindrical model in two beagle dogs. Four prostheses were implanted into each femur through the lateral cortex, for a total of eight of each type, and remained in place for 12 weeks. Except for the proximal implant, push-out tests were performed to measure the shear strength of fixation of the implants to the cortical bone. For observations of the implant-bone interface, decalcified specimens of the proximal femur were stained with toluidine blue and observed with an optical microscope. The mean push-out strength of the Laser type was approximately 10.2 MPa and that of the Beads type was approximately 10.7 MPa. There was no significant difference in interface push-out strength between the groups. Bone ingrowth into both types was sufficient, however, some specimens of the Beads type demonstrated displacement of some of the beads from the rod surface. This study indicates that a porous surface created with a YAG laser might be useful not only for its shear strength, but also for the strength of the surface itself.


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 6 | Pages 796 - 801
1 Aug 2003
Ito H Matsuno T Omizu N Aoki Y Minami A

We followed, prospectively, 77 patients (90 hips) with early-stage, non-traumatic osteonecrosis of the femoral head for a mean period of nine years. At the time of final review, 56 (62%) were symptomatic. Using the Cox model, the initial radiological stage, the progression of staging, the reduction in size of the lesions and the percentage of necrotic volume on MRI were identified as risk factors.

Using the Harris score of < 70 or surgery as the endpoint, the cumulative rates of survival were 60.0% at one year, 43.3% at two years, 38.9% at five years and 37.2% at ten years. Survival curves demonstrated that clinical deterioration could occur 90 months after the initial diagnosis, suggesting that asymptomatic patients should be followed carefully for several years. Radiological time-dependent reduction in size without progressive collapse may represent repair even when the collapse is minimal.


The Journal of Bone & Joint Surgery British Volume
Vol. 85-B, Issue 2 | Pages 204 - 208
1 Mar 2003
Ito H Matsuno T Minami A

We present the mid- to long-term results of the Chiari pelvic osteotomy for dysplastic hips. We followed 135 hips in 129 patients, with a mean age at the time of surgery of 24 years, for a mean of 16.2 years. We used the anterior iliofemoral approach without trochanteric osteotomy in the initial 31 hips. Thereafter, we used transtrochanteric approaches in an attempt to ensure that the osteotomy was at the most appropriate level, and to advance the high-riding greater trochanter distally. The next 79 hips therefore underwent a posterolateral approach and the most recent 25 hips an Ollier lateral U approach. The clinical result was excellent or good in 103 hips (77%). The outcome in 104 hips in which we used a transtrochanteric approach was superior, the osteotomy level was more appropriate and a Trendelenburg gait less common than in 31 hips in which we used an anterior approach. We therefore recommend the use of a transtrochanteric approach in order to ensure that the osteotomy is at an appropriate level and in order to achieve effective distal advancement of the high-riding greater trochanter.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 31 - 31
1 Jan 2003
Takemitsu M Takemitsu Y Matsuno T Atsuta Y Kobayashi T Iwahara T Kamo Y
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Lumbar Degenerative Kyphosis (LDK) is a clinical entity showing kyphosis in the lumbar spine in elderly with multilevel disc narrowing and a varied degree of osteoporosis. LDK patient complains of stooped gait with persistent low back pain and weakness. Purpose of this paper is to study the lumbar muscle in LDK patients with histopathologic and biophysical evaluations to investigate the pathogenesis.

Materials and Methods: 1. Intramuscular pressure (IMP) (a) of the lumbar extensor compartment and hemoglobin content (Hb)□@(b) of 25 young volunteers were also investigated comparing in standing upright and flexion positions using (a)□@pressure monitoring kits and an non-invasive oxygenation monitor. 2.Muscle biopsy specimens obtained from the lumbar extensors of 9 LDK patients were histopathologically examined with HE, cytochrome c oxidase and other methods. These data were compared with muscles taken from age-match controls. Mitochondria function was also examined on biochemistry.

1. IMP of the extensors markedly increased in the flexion position (130.0□}45.4 in males and 86.3 mmHg in fem.) comparing to straight upright□@(22.8□}14.4, 17.0□}6.0). Oxy-Hb concentration decreased from 100% to 92.9, 95.5 % respectively in flexion, which was a sign of ischemia. 2. Both multifidus and sacrospinalis m. showed moderate to marked interstitial fibrosis, decreased number of muscle fibers and decreased stain intensity of cytochrome c oxidase. These finding were similar to those seen in repeatedly compressed muscles of an animal model of the chronic compartment syndrome. In comparison the rectus abd. and psoas muscles in the patients showed almost normal except for some aging changes. Conclusion: There appeared to be definite atrophy of the lumbar extensor muscles with histochemical and biochemical methods in LDK patients, whereas the flexors showed no change. This extensor atrophy is limited in the lumbar region in LDK. These localized atrophy of the lumbar extensors would suggest a result of high IMP during working in deep bending position of the spine for many years and may play important role in etiology of this disease condition.


The Journal of Bone & Joint Surgery British Volume
Vol. 82-B, Issue 3 | Pages 375 - 377
1 Apr 2000
Inao S Matsuno T

We carried out primary cemented total hip arthroplasty (THA) on 25 hips in 21 patients with developmental dysplasia of the hip, using autogenous acetabular bone grafts. The socket was placed at the level of the true acetabulum and bone from the femoral neck was used as graft. Five hips were excluded, leaving 20 which were followed up for a mean of 12.9 years (10 to 18).

The mean modified Merle d’Aubigné and Postel functional scores were 5.6 for pain, 4.3 for mobility and 4.2 for range of movement. Radiological examination showed aseptic loosening in three sockets but not in the stems. The bone grafts had united and showed no evidence of late failure.


The Journal of Bone & Joint Surgery British Volume
Vol. 81-B, Issue 6 | Pages 969 - 974
1 Nov 1999
Ito H Kaneda K Matsuno T

We present the long-term results of simple varus intertrochanteric osteotomy for osteonecrosis of the femoral head. We followed 26 hips in 20 patients, with a mean age at the time of surgery of 36 years, for a mean of 12.5 years. The mean varus angulation was 23°.

The outcome in 19 of the hips (73%) was good or excellent; seven (27%) had a fair or poor result, with four needing some form of prosthetic arthroplasty.

Simple varus intertrochanteric osteotomy is indicated, even if the extent of the capital infarct comprises more than 50% of the diameter of maximum radial distance from the circumference, provided that after operation the medial necrotic lesion measures less than two-thirds of the weight-bearing area, and the superolateral bone is normal.