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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 245 - 245
1 Sep 2012
Khan L Will E Keating J
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Introduction

The aims of this study were to undertake a prospective randomised trial to compare functional outcome, strength and range of motion after treatment of medial collateral ligament injuries by either early unprotected mobilisation or mobilisation with a hinged brace.

Methods

Patients were randomised into either unprotected mobilisation or mobilisation with a hinged brace. Assessments occurred at 2 weeks, 6 weeks, 3 months and 6 months. Outcome measures included validated questionnaires (International Knee Documentation Committee and Knee Injury and Osteoarthritis Outcome Score scores), range of motion measurements and strength testing.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 123 - 123
1 Sep 2012
Khan L Page R Miller L Graves S
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Aims

To report the rate of early revision (within two years) after shoulder arthroplasty and identify any patient, disease or prosthesis factors that may be associated with these early failures.

Methods

The AOA National Joint Replacement Registry has recorded 7113 shoulder arthroplasty procedures up to December 2009. Data recorded includes diagnosis, patient demographics and prosthesis details. The main outcome of this analysis was the time to first revision of all primary shoulder arthroplasty recorded by the Registry.

The cumulative per cent revision (CPR) of shoulder arthroplasty procedures was estimated using the Kaplan-Meier method. Cox proportional hazard models were used to test significance between groups


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 182 - 182
1 Sep 2012
Khan L Wallace R Simpson A Robinson C
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Aims

The aim of this study was to compare biomechanical properties of pre-contoured plate fixation using different screw fixation modes in a mid-shaft clavicle fracture model.

Methods

Fourth generation biomechanical clavicle sawbones with a mid-shaft osteotomy were plated in one of three modes: nonlocking bicortical, locking bicortical and locking unicortical mode. The specimens were then tested to failure in four-point bending and pull-off tests.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 69 - 69
1 Feb 2012
Khan L Robinson C Will E Whittaker R
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Our purpose was to study the functional outcome and electrophysiologically to assess the axially nerve function in patients who have undergone surgery using a deltoid-splitting approach to treat complex proximal humeral fractures.

This was a prospective observational study and was carried out in the Shoulder injury clinic at a university teaching hospital. Over a one-year period we treated fourteen locally-resident patients (median age 59 years) who presented with a three- or four-part proximal humeral fracture. All patients were treated using the extended deltoid-splitting approach, with open reduction, bone grafting and plate osteosynthesis. All patients were prospectively reviewed and underwent functional testing using the DASH, Constant and SF-36 scores as well as spring balance testing of deltoid power, and dynamic muscle function testing. At one year after surgery, all patients underwent EMG and nerve latency studies to assess axillary nerve function.

Thirteen of the fourteen patients united their fractures without complications, and had DASH and Constant score that were good, with comparatively minor residual deficits on assessment of muscle power. Of these thirteen patients, only one had evidence of slight neurogenic change in the anterior deltoid. This patient had no evidence of anterior deltoid paralysis and her functional scores, spring balance and dynamic muscle function test results were indistinguishable from the patients with normal electrophysiological findings. One of the fourteen patients developed osteonecrosis of the humeral head nine months after surgery and had poor functional scores, without evidence of nerve injury on electrophysiological testing.

Reconstruction through an extended deltoid-splitting approach provides a useful alternative in the treatment of complex proximal humeral fractures. The approach provides good access for reduction and implant placement and does not appear to be associated with clinically-significant adverse effects.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 98 - 98
1 May 2011
Khan L Wallace R Robinson C Simpson A
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Background and Aims: Plate fixation of acute mid-shaft clavicle fractures is becoming increasingly popular. However limb and life threatening complications such as injury to the subclavian vessels have been reported. One possible solution to reduce the risk of this complication is the use of unicortical screw fixation.

The aim of this study was to compare biomechanical properties of pre-contoured plate fixation using different screw fixation modes in a mid-shaft clavicle fracture model.

Methods: Fourth generation biomechanical clavicle sawbones with a mid-shaft osteotomy were plated in one of three modes: nonlocking bicortical, locking bicortical and locking unicortical mode. The specimens were then tested to failure in four-point bending and pull-off tests.

Results: Failure due to fracture through the sawbone was more common in nonlocking bicortical mode while plate bending was more common in the locking bicortical group. The ultimate load at failure was significantly lower in the locking bicortical group compared to the nonlocking bicortical group, however there was no significant difference between the locking unicortical group and nonlocking bicortical group.

In the pull-off tests 100% of nonlocking bicortical and locking bicortical plates failed by fracture of the sawbone. 100% of the locking unicortical plates failed by plate and screw pull-off from the sawbone. The load at failure was highest for the locking unicortical plate but this was not significantly different to the other groups.

Conclusion: This study shows that specimens fixed with locking unicortical screw fixation withstood comparable or superior loads in four-point bending and pull-off test when compared to nonlocking bicortical and locking bicortical screw fixation. In addition both locking screws and unicortical screws appear to provide a protective effect against periprosthetic sawbone fracture. Locking unicortical screw fixation of pre-contoured plates may be a viable alternative in the fixation of mid-shaft clavicle fractures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 134 - 134
1 Mar 2009
cowie J Khan L Ballantyne J Brenkel I
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Aim: To study the effect of smoking on the rate of complications and functional outcome after Total Hip Replacement (THR).

Methods: Data was prospectively collected for all patients undergoing a unilateral, primary THR in one hospital during the period 1998 to 2006 Data was collected at pre-operative assessment, in the peri-operative period and at 6 months, 18 months, 3 years and 5 years. Patients were placed in one of three groups; smokers, ex-smokers and those who had never smoked.

Outcome measures included rate of complications: infection, DVT, PE, length of hospital stay and Harris Hip Score (HHS).

Statistical analysis was undertaken to determine any correlation between smoking and these outcome measures using chi-squared tests, t-tests and multiple regression adjusting for confounding factors.

Results: 1765 patients underwent THR during the study period, of whom 635 were males and 1130 females, with a mean age at operation of 69.

268 patients (15%) were smokers, 582 patients (33%) were ex-smokers and 917 patients (52%) had never smoked. As there was little data available on when the ex-smokers had stopped smoking we studied current smokers compared to patients that had never smoked

There were no significant differences in complications such as DVT, PE, Deep infection and Superficial infection, these were all rare events. Neither was there any significant difference in hospital stay times. After adjusting for pre-operative HHS, age, sex and ASA status current smokers had significantly lower HHS at 6 months (p< 0.001, 95% confidence interval for effect size 1.6 to 5.3), and also showed a lower HHS at 18 months, 3 years and 5 years although not significantly so.

Conclusion: Current smokers have a significantly lower HHS post-operatively in comparison to non-smokers. In a health system where more and more patients wish to know the risk associated with potential operative interventions, we can now say that patients who smoke will have a poorer outcome post Total Hip Replacement. This may also allow us to discourage some patients wishing to have THR whom are poor operative candidates.

We plan to further analysis the data to try and ascertain why this is the case.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 247 - 247
1 May 2006
Robinson C Houshian S Khan L
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The purpose of this study was to prospectively audit the functional outcome and peri-operative complications associated with the use of a trochantericentry cephalomedullary nail to treat all low-energy subtrochanteric fractures.

Methods: Over a 95 month period, we used the Long Gamma Nail (LGN) to treat a consecutive series of 302 locally-resident patients who sustained subtrochanteric fractures during low-energy trauma. We prospectively assessed the mortality, prevalence of complications and functional outcome during the first year post-injury. We used survivorship methodology to assess the rate of re-operations and implant revision during the first year after surgery.

Results: By one year, 74 patients had died, 10 were untraceable and 7 refused to participate in follow-up. The remaining 211 patients had evaluation of their functional outcome and post-operative complications during the first year post-injury.

The prognosis following an operatively-treated subtrochanteric fracture was similar to other proximal femoral fractures, with a one-year mortality of 24.5%, and an increased level of social dependence, increased use of walking aids and reduction in mobility amongst survivors.

Re-operation was required in 27 patients (8.9%), although only 18 patients required nail revision. On survivorship analysis, 96.8% of fractures had healed by six months post-injury, and only five patients had confirmed non-unions, which were successfully treated with autogenous bone grafting. Lag-screw mechanical failure and fractures distal to the nail were seen in twelve (4%) and five (1.7%) patients respectively; all of these fractures subsequently healed after further treatment. Deep sepsis occurred in only five (1.7%) patients.

Conclusions: Subtrochanteric fractures caused by low-energy trauma have similar prognosis to other proximal femoral fractures. Trochanteric-entry cephalomedullary nails are a versatile treatment option for these injuries, and are associated with an acceptable rate of peri-operative complications and favourable functional outcome.