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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 468 - 468
1 Jul 2010
Rose P Yaszemski M Dekutoski M Huddleston P Nassr A Shives T Sim F
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Curative treatment of malignancies in the sacrum and lower lumbar spine frequently requires en bloc spinopelvic resection. There is no standard classification of these procedures. We present outcomes and a classification scheme with oncologic and reconstructive guidelines for spinopelvic tumors based on an analysis of 30 cases of en bloc resection and reconstruction performed with curative intent.

Mean follow-up of surviving patients was 38 months. Tumors included osteosarcoma (n=9), chondrosarcoma (n=6), chordoma (n=5), other sarcomas (n=5), neurogenic tumors (n=4), and local extension of carcinoma (n=1). Resections could be divided into 4 types. Type 1 resections (n=12) included a total sacrectomy with lower lumbar spine and bilateral medial iliac resections. Type 2 resections (n=6) included hemisacrectomy, partial lumbar spine excision, and medial iliac resection. Type 3 resections (n=9) encompassed external hemipelvectomy with hemisacrectomy and partial lumbar spine excision. Type 4 resections (n=3) encompassed external hemipelvectomy, total sacrectomy, and lumbar spine excision.

For each resection type, we have developed staged surgical approaches to allow resection with wide margins and reconstruction of spinopelvic continuity. Tumor free margins were achieved in all cases. Perioperative mortality was 3/30. Seven additional patients have died of disease, two died of other causes, two are alive with disease, and 16 have no evidence of disease. 13/18 surviving patients are independent in their activities of daily living.

In our practice en bloc excision and reconstruction of spinopelvic neoplasms may be classified into four types. For each type, we have devised surgical treatment guidelines to allow for wide resection and reconstruction of spinopelvic continuity. Long term survival and independent function can be achieved in this challenging patient population. This represents the first standardised classification of oncologic spinopelvic resections and reconstructions.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 233 - 233
1 May 2009
Perkins P Burd T Huddleston P Knapp K Kovalsky D Robbins S Wood K
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We present our experience with the use of the Anterior Tension Band plate (ATB) following ALIF, which utilises the existing surgical approach obviating the need for posterior fixation. The ATB is a small, smooth, low profile plate. It can be placed through the existing approach (anterolateral retroperitoneal or anterior transperitoneal) across the reconstructed level to prevent extension of the graft space and anterior migration of the spacer. The primary objective of this study is to measure radiographic fusion success in patients with lumbar degenerative disc disease using the ATB system. The secondary objective is to accurately define the clinical benefits to the patient.

This is a prospective multi-center outcome study. Each patient was treated with an ATB plate at one or two levels between L2 & S1 and 1 ALIF or FRA allograft spacer per level. Patient data (VAS Pain, SF-12 and Oswestry) was collected preoperatively, and at six, twelve and twenty-four month post-operative intervals. Fusion was evaluated upon demonstration of bridging trabecular bone through or external to the femoral ring. Secondary endpoint success includes demonstration of 15% improvement over baseline on the VAS, Oswestry and SF-12 patient questionnaires.

To date one hundred and thirty-one patients have undergone surgery. There were ninety-two (70%) single-level ALIF procedures and thirty-nine (30%) two-level ALIF procedures. Patients that have returned for twelve month follow-up (n=41) have had a fusion success rate of 81%. The fusion rate among one-level patients is 89% (n=25) and 67% (n=15) among two-level patients. Four of five of the un-fused two-level patients had one level fused but not the other. At twelve months, Oswestry scores improved by an average of 40% with thirty-one of forty-seven (66%) patients achieving success and VAS scores improved by 42% with thirty-five of forty-seven (75%) being successful.

Preliminary analysis of current data shows positive outcomes using the ATB plating system in ALIF procedures. Primary and secondary outcomes are compatible with current standards of care, and device related complications are minimal. Further analysis of outcome data including will be reported upon the completion of the study.