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The Bone & Joint Journal
Vol. 106-B, Issue 4 | Pages 394 - 400
1 Apr 2024
Kjærvik C Gjertsen J Stensland E Dybvik EH Soereide O

Aims

The aims of this study were to assess quality of life after hip fractures, to characterize respondents to patient-reported outcome measures (PROMs), and to describe the recovery trajectory of hip fracture patients.

Methods

Data on 35,206 hip fractures (2014 to 2018; 67.2% female) in the Norwegian Hip Fracture Register were linked to data from the Norwegian Patient Registry and Statistics Norway. PROMs data were collected using the EuroQol five-dimension three-level questionnaire (EQ-5D-3L) scoring instrument and living patients were invited to respond at four, 12, and 36 months post fracture. Multiple imputation procedures were performed as a model to substitute missing PROM data. Differences in response rates between categories of covariates were analyzed using chi-squared test statistics. The association between patient and socioeconomic characteristics and the reported EQ-5D-3L scores was analyzed using linear regression.


The Bone & Joint Journal
Vol. 104-B, Issue 7 | Pages 884 - 893
1 Jul 2022
Kjærvik C Gjertsen J Stensland E Saltyte-Benth J Soereide O

Aims

This study aimed to identify risk factors (patient, healthcare system, and socioeconomic) for mortality after hip fractures and estimate their relative importance. Further, we aimed to elucidate mortality and survival patterns following fractures and the duration of excess mortality.

Methods

Data on 37,394 hip fractures in the Norwegian Hip Fracture Register from January 2014 to December 2018 were linked to data from the Norwegian Patient Registry, Statistics Norway, and characteristics of acute care hospitals. Cox regression analysis was performed to estimate risk factors associated with mortality. The Wald statistic was used to estimate and illustrate relative importance of risk factors, which were categorized in modifiable (healthcare-related) and non-modifiable (patient-related and socioeconomic). We calculated standardized mortality ratios (SMRs) comparing deaths among hip fracture patients to expected deaths in a standardized reference population.


The Bone & Joint Journal
Vol. 104-B, Issue 2 | Pages 274 - 282
1 Feb 2022
Grønhaug KML Dybvik E Matre K Östman B Gjertsen J

Aims

The aim of this study was to investigate if there are differences in outcome between sliding hip screws (SHSs) and intramedullary nails (IMNs) with regard to fracture stability.

Methods

We assessed data from 17,341 patients with trochanteric or subtrochanteric fractures treated with SHS or IMN in the Norwegian Hip Fracture Register from 2013 to 2019. Primary outcome measures were reoperations for stable fractures (AO Foundation/Orthopaedic Trauma Association (AO/OTA) type A1) and unstable fractures (AO/OTA type A2, A3, and subtrochanteric fractures). Secondary outcome measures were reoperations for A2, A3, and subtrochanteric fractures individually, one-year mortality, quality of life (EuroQol five-dimension three-level index score), pain (visual analogue scale (VAS)), and satisfaction (VAS) for stable and unstable fractures. Hazard rate ratios (HRRs) for reoperation were calculated using Cox regression analysis with adjustments for age, sex, and American Society of Anesthesiologists score.


Bone & Joint Open
Vol. 2, Issue 9 | Pages 710 - 720
1 Sep 2021
Kjaervik C Gjertsen J Engeseter LB Stensland E Dybvik E Soereide O

Aims

This study aimed to describe preoperative waiting times for surgery in hip fracture patients in Norway, and analyze factors affecting waiting time and potential negative consequences of prolonged waiting time.

Methods

Overall, 37,708 hip fractures in the Norwegian Hip Fracture Register from January 2014 to December 2018 were linked with data in the Norwegian Patient Registry. Hospitals treating hip fractures were characterized according to their hip fracture care. Waiting time (hours from admission to start of surgery), surgery within regular working hours, and surgery on the day of or on the day after admission, i.e. ‘expedited surgery’ were estimated.


Bone & Joint Open
Vol. 2, Issue 7 | Pages 454 - 465
8 Jul 2021
Kristoffersen MH Dybvik EH Steihaug OM Kristensen TB Engesæter LB Ranhoff AH Gjertsen J

Aims

Hip fracture patients have high morbidity and mortality. Patient-reported outcome measures (PROMs) assess the quality of care of patients with hip fracture, including those with chronic cognitive impairment (CCI). Our aim was to compare PROMs from hip fracture patients with and without CCI, using the Norwegian Hip Fracture Register (NHFR).

Methods

PROM questionnaires at four months (n = 34,675) and 12 months (n = 24,510) after a hip fracture reported from 2005 to 2018 were analyzed. Pre-injury score was reported in the four-month questionnaire. The questionnaires included the EuroQol five-dimension three-level (EQ-5D-3L) questionnaire, and information about who completed the questionnaire.


The Bone & Joint Journal
Vol. 102-B, Issue 12 | Pages 1662 - 1669
1 Dec 2020
Pollmann CT Gjertsen J Dale H Straume-Næsheim TM Dybvik E Hallan G

Aims

To compare the functional outcome, health-related quality of life (HRQoL), and satisfaction of patients who underwent primary total hip arthroplasty (THA) and a single debridement, antibiotics and implant retention (DAIR) procedure for deep infection, using either the transgluteal or the posterior surgical approach for both procedures.

Methods

The study was registered at clinicaltrials.gov (ID: NCT03161990) on 15 May 2017. Patients treated with a single DAIR procedure for deep infection through the same operative approach as their primary THA (either the transgluteal or the posterior approach) were identified in the Norwegian Arthroplasty Register and given a questionnaire. Median follow-up after DAIR by questionnaire was 5.5 years in the transgluteal group (n = 87) and 2.5 years in the posterior approach group (n = 102).


Bone & Joint Open
Vol. 1, Issue 10 | Pages 644 - 653
14 Oct 2020
Kjærvik C Stensland E Byhring HS Gjertsen J Dybvik E Søreide O

Aims

The aim of this study was to describe variation in hip fracture treatment in Norway expressed as adherence to international and national evidence-based treatment guidelines, to study factors influencing deviation from guidelines, and to analyze consequences of non-adherence.

Methods

International and national guidelines were identified and treatment recommendations extracted. All 43 hospitals routinely treating hip fractures in Norway were characterized. From the Norwegian Hip Fracture Register (NHFR), hip fracture patients aged > 65 years and operated in the period January 2014 to December 2018 for fractures with conclusive treatment guidelines were included (n = 29,613: femoral neck fractures (n = 21,325), stable trochanteric fractures (n = 5,546), inter- and subtrochanteric fractures (n = 2,742)). Adherence to treatment recommendations and a composite indicator of best practice were analyzed. Patient survival and reoperations were evaluated for each recommendation.


The Bone & Joint Journal
Vol. 101-B, Issue 9 | Pages 1129 - 1137
1 Sep 2019
Leer-Salvesen S Engesæter LB Dybvik E Furnes O Kristensen TB Gjertsen J

Aims

The aim of this study was to investigate mortality and risk of intraoperative medical complications depending on delay to hip fracture surgery by using data from the Norwegian Hip Fracture Register (NHFR) and the Norwegian Patient Registry (NPR).

Patients and Methods

A total of 83 727 hip fractures were reported to the NHFR between 2008 and 2017. Pathological fractures, unspecified type of fractures or treatment, patients less than 50 years of age, unknown delay to surgery, and delays to surgery of greater than four days were excluded. We studied total delay (fracture to surgery, n = 38 754) and hospital delay (admission to surgery, n = 73 557). Cox regression analyses were performed to calculate relative risks (RRs) adjusted for sex, age, American Society of Anesthesiologists (ASA) classification, type of surgery, and type of fracture. Odds ratio (OR) was calculated for intraoperative medical complications. We compared delays of 12 hours or less, 13 to 24 hours, 25 to 36 hours, 37 to 48 hours, and more than 48 hours.


The Bone & Joint Journal
Vol. 100-B, Issue 12 | Pages 1565 - 1571
1 Dec 2018
Kristensen TB Dybvik E Furnes O Engesæter LB Gjertsen J

Aims

The aim of this large registry-based study was to compare mid-term survival rates of cemented femoral stems of different designs used in hemiarthroplasty for a fracture of the femoral neck.

Patients and Methods

From the Norwegian Hip Fracture Register (NHFR), 20 532 primary cemented bipolar hemiarthroplasties, which were undertaken in patients aged > 70 years with a femoral neck fracture between 2005 and 2016, were included. Polished tapered stems (n = 12 065) (Exeter and CPT), straight stems (n = 5545) (Charnley, Charnley Modular, and Spectron EF), and anatomical stems (n = 2922) (Lubinus SP2) were included. The survival of the implant with any reoperation as the endpoint was calculated using the Kaplan–Meier method and hazard ratios (HRs), and the different indications for reoperation were calculated using Cox regression analysis.


The Bone & Joint Journal
Vol. 95-B, Issue 6 | Pages 862 - 862
1 Jun 2013
Gjertsen J Lie SA Vinje T Engesæter LB Hallan G Matre K Furnes O

We welcome letters to the Editor concerning articles that have recently been published. Such letters will be subject to the usual stages of selection and editing; where appropriate the authors of the original article will be offered the opportunity to reply.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 28 - 28
1 Sep 2012
Vinje T Gjertsen J Lie S Engesaeter L Havelin L Furnes O Matre K Fevang J
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Background

Systematic reviews disagree, but some recent studies have shown better function and less pain after operation with bipolar hemiarthroplasty compared to fixation by two screws in elderly patients operated for displaced femoral neck fractures. There is still uncertainty regarding the mortality associated with both procedures.

Aim of the study

To investigate mortality and the risk factors for death among patients with displaced femoral neck fractures within the first three years after surgery, comparing operation with bipolar hemiarthroplasty (HA) and internal fixation (IF) by two screws.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 30 - 30
1 Sep 2012
Vinje T Fevang J Engesaeter L Lie S Havelin L Matre K Gjertsen J Furnes O
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Background

A well conducted randomised study found similar functional results for patients with displaced femoral neck fracture comparing operation with a modern uncemented bipolar hemiarthroplasty with a cemented bipolar hemiarthroplasty. The mortality associated with the two procedures has not been sufficiently investigated.

Aim of study

To investigate the mortality and the risk factors for death among patients with displaced femoral neck fractures the first year after surgery, comparing operation with modern uncemented and cemented bipolar hemiarthroplasty (HA).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 31 - 31
1 Sep 2012
Gjertsen J Vinje T Fevang J Lie SA Furnes O Havelin LI Engesaeter LB
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Introduction

Displaced femoral neck fractures in elderly are normally treated with 2 screws/pins (IF) or bipolar hemiarthroplasty (HA). The aim of this study was to compare IF and HA as treatment for displaced femoral neck fractures using reoperations and functional result (patient satisfaction, pain, and quality of life) as outcome.

Material and Methods

From January 2005 all hip fractures in Norway are reported to the Norwegian Hip Fracture Register. At 4, 12, and 36 months postoperatively a questionnaire assessing satisfaction (VAS 0-100), pain (VAS 0-100), and quality of life (EQ-5D) is sent to the patients. To ensure more than 3 years follow-up, only patients operated in 2005 were included in the present study. Consequently 1,968 patients over 70 years of age operated with IF (n = 958) or HA (n = 1,010) due to displaced femoral neck fractures were included in the analyses on reoperations. Of these, 280 patients responded to all questionnaires and were included in the analyses on functional results (IF: n = 135, HA: n = 145). The patients remained in the same treatment group according to the intention-to-treat principle.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 26 - 26
1 Sep 2012
Gjertsen J Fevang J Vinje T Matre K Engesaeter LB
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Introduction

Undisplaced femoral neck fractures have been given little attention in the literature. By using data from the Norwegian Hip Fracture Register, this study investigates risk for reoperation and the clinical results, including pain, patient satisfaction, and quality of life, after undisplaced femoral neck fractures in elderly patients.

Material and Methods

Data on 4,468 patients over 70 years of age with undisplaced femoral neck fractures operated with internal fixation (IF) were compared to 10,289 patients with displaced femoral neck fractures treated with IF (n = 3,389) or bipolar hemiarthroplasty (n = 6,900). The evaluation was based on number of reported reoperations and patients' assessment (visual analogue scales concerning pain (0–100) and patient satisfaction (0–100), and quality of life (EQ-5D)) four and twelve months postoperatively. The patients were followed for 0–1 year. The Cox multiple regression model was used to construct adjusted survival curves. Subanalyses were performed on undisplaced femoral neck fractures to investigate different risk factors for reoperation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 230 - 230
1 Sep 2012
Matre K Vinje T Havelin LI Gjertsen J Furnes O Espehaug B Fevang J
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Introduction

The treatment of trochanteric and subtrochanteric fractures remains controversial, and new implants are constantly being developed trying to improve outcome and minimize the number of complications in these fractures.

In Norway the Sliding Hip Screw(SHS), with or without a Trochanteric Stabilizing Plate (TSP), is still the most commonly used implant, but worldwide nailing of these fractures is increasing. This trend, however, has not been supported by documentation of better clinical results compared to the SHS in well designed studies. Therefore, in the present study we compared the recently launched Trigen Intertan nail (Smith and Nephew) with the SHS in the treatment of trochanteric and subtrochanteric fractures.

Patients and Methods

In a prospective, randomized multicenter study with 697 patients, we compared the Trigen Intertan nail with the SHS regarding postoperative pain, functional mobility, complications, and reoperation rates.

Patients older than 60 years with trochanteric and subtrochanteric fractures were included in 5 hospitals. At day 5, and 3 and 12 months postoperatively, pain was measured using a Visual Analogue Scale (VAS), and the Timed Up and Go-test (TUG-test) was performed to evaluate functional mobility. Complications and reoperations were recorded at discharge, and after 3 and 12 months.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 8 | Pages 1113 - 1119
1 Aug 2012
Gjertsen J Lie SA Vinje T Engesæter LB Hallan G Matre K Furnes O

Using data from the Norwegian Hip Fracture Register, 8639 cemented and 2477 uncemented primary hemiarthroplasties for displaced fractures of the femoral neck in patients aged > 70 years were included in a prospective observational study. A total of 218 re-operations were performed after cemented and 128 after uncemented procedures. Survival of the hemiarthroplasties was calculated using the Kaplan-Meier method and hazard rate ratios (HRR) for revision were calculated using Cox regression analyses. At five years the implant survival was 97% (95% confidence interval (CI) 97 to 97) for cemented and 91% (95% CI 87 to 94) for uncemented hemiarthroplasties. Uncemented hemiarthroplasties had a 2.1 times increased risk of revision compared with cemented prostheses (95% confidence interval 1.7 to 2.6, p < 0.001). The increased risk was mainly caused by revisions for peri-prosthetic fracture (HRR = 17), aseptic loosening (HRR = 17), haematoma formation (HRR = 5.3), superficial infection (HRR = 4.6) and dislocation (HRR = 1.8). More intra-operative complications, including intra-operative death, were reported for the cemented hemiarthroplasties. However, in a time-dependent analysis, the HRR for re-operation in both groups increased as follow-up increased.

This study showed that the risk for revision was higher for uncemented than for cemented hemiarthroplasties.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 134 - 134
1 May 2011
Matre K Vinje T Havelin L Gjertsen J Furnes O Espehaug B Fevang J
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Background: The treatment of trochanteric and subtrochanteric fractures is still controversial. In Norway the most commonly used implant for these fractures is the Sliding Hip Screw (SHS), with or without a trochanteric support plate. The Intertan nail (Smith & Nephew) has been launched as a nail with improved biomechanical properties for the treatment of these fractures, but so far it has not been shown that the clinical results are superior to the traditional Sliding Hip Screw.

We wanted to investigate any differences in pain and function between the new Intertan nail and the Sliding Hip Screw in the early postoperative phase.

Materials and Methods: 665 patients older than 60 years with a trochanteric or subtrochanteric fracture were randomized to either a SHS (CHS/DHS) or an Intertan nail in 5 hospitals. For practical reasons only 315 patients (47%) were evaluated at day 5 postoperatively (163 Intertan and 152 SHS), and these patients were used for our analysis. Pain was measured using a Visual Analog Scale (VAS), and early functional mobility by the “Timed Up and Go”- test (TUG-test). T-tests and chi-square tests were used to examine differences between the groups.

Results: The average pain at rest was similar for the 2 groups (VAS 21). Pain at mobilization, however, differed, where patients operated with the Intertan nail had less pain than those operated with the SHS (VAS 47 vs. 53, p = 0.02). The difference between the implants was most pronounced for the simple two-part fractures (AO Type A1). More patients treated with the nail than with the SHS performed the TUG-test at day 5 (85/163 vs. 63/152, p = 0.06), but there was no statistically significant difference regarding the average speed the TUG-test was performed with (71 vs. 66sec, p = 0.36). The implant type did not influence the length of hospital stay.

Discussion/Conclusion: Regarding early postoperative pain and function, there seems to be similar or better results for trochanteric and subtrochanteric fractures treated with the Intertan nail compared to the SHS. The difference in measured pain level was statistically significant, but may not be clinically significant (a difference of VAS 6). We could not detect any significant differences in terms of early functional mobility between the two implants.

In our opinion it still remains to show good long-term results and acceptable complication rates before the new Intertan nail is widely taken into use. Due to the additional costs for the Intertan nail also economic aspects should be considered when choosing the implant and operative method for these fractures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 169 - 169
1 Mar 2009
vinje T fevang J gjertsen J lie S engesaeter L havelin L matre K furnes O
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Aims: To calculate one-year survival after dislocated intracapsular femoral neck fractures and to assess factors associated with increased risk of death.

Patients: 2045 patients treated for dislocated intracapsular femoral neck fractures during 2005 were registered in The Norwegian Hip Fracture Registry and were included in the present study.

Methods: Almost all hospitals in Norway reported proximal femoral fractures to the Registry using standard forms filled in by the operating surgeons. Survival was calculated using Kaplan Meier survival analyses, and the impact of factors possibly influencing the survival was estimated using Cox regression analysis. Mortality data for all patients were obtained from Statistics Norway.

Results: 2045 patients having dislocated intracapsular femoral neck fractures operated with 2 pins/screws (1071) and bipolar hemiprosthesis (974) were enrolled in the Registry during 2005. Among these, 333 patients died within the first year after the operation; 2 pins/screws (170) and bipolar hemiprosthesis (163). Factors adversely associated with survival included high age, male gender, dementia and with an increase in preoperative ASA classification. No statistically significant difference was found regarding preoperativ delay or for the two different treatment methods.

Conclusion: After one year there is no difference in risk of death between operation methods; 2 pins/screws and hemiprosthesis, for dislocated femoral neck fractures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 165 - 165
1 Mar 2009
Gjertsen J Fevang J Vinje T Lie S Havelin L Ebgesaeter L Furnes O
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Background: Annually about 9,000 patients in Norway are operated because of hip fractures. From January 2005 all these fractures should be reported to The Norwegian Hip Fracture Register, founded by the Norwegian Orthopaedic Association and operated by The Norwegian Arthroplasty Register from 1. January 2005.

Patients and methods: We have established contacts at every hospital in Norway that perform surgery for hip fractures. Immediately after the surgery the surgeon fills in a standardized form which is sent to the register once a month. On the form there are both patient- and procedure-related questions. Four and twelve months postoperatively we send a questionnaire to the patients, including the Norwegian translation of the EuroQol-5D. Patient information is linked to the Norwegian Death Register using the unique identification number assigned for each resident of Norway. We have so far included 5,668 primary hip fractures operations and 607 revision procedures including revisions to hemiprosthesis and total hip replacements (THR).

Results: After 1 year of registration 100 % of the hospitals are reporting to the register. Approximately 50 % of the patients have answered the questionnaire. Of the primary operated patients the mean age was 80.5 years and 73 % were females. 59 % of the fractures were intracapsular femoral neck fractures and approximately 2/3 of those were dislocated. 35 % of the fractures were intertrochanteric or subtrochanteric.

Intracapsular dislocated fractures: Screw fixation was used in 48 % of the hips while 46 % of the hips were operated with a hemiarthroplasty, and 4.1 % were operated with a THR. We could not find any difference in mortality between screw fixated patients and patients operated with a hemiarthroplasty.

Intertrochanteric/subtrochanteric fractures: The hip compression screw osteosynthesis was used in 88 % of the patients, 6.3 % of these had a lateral support plate. An intramedullary nail was used in 8.9 % of the patients.

Conclusion: After only one year, the reports from the surgeons were good. Taking the age and general status into consideration, also the response from the patients is satisfactory. With longer follow-up we will be able to give more information on the outcomes of hip fractures and of the different treatment. Updated analysis will be reported.