header advert
Results 1 - 6 of 6
Results per page:
The Bone & Joint Journal
Vol. 95-B, Issue 8 | Pages 1052 - 1056
1 Aug 2013
Lampropoulou-Adamidou K Georgiades G Vlamis J Hartofilakidis G

We evaluated the outcome of 41 consecutive Charnley low-friction arthroplasties (LFAs) performed by a single surgeon in 28 patients aged ≤ 35 years at operation between 23 and 36 years previously. There were 20 women and eight men with a mean age of 32 years (23 to 35) at surgery. Two patients (three hips) were lost to follow-up at 12 and 17 years post-operatively, respectively, and one patient (one hip) died at 13 years post-operatively. These patients were excluded from the final evaluation. The survival rate of the acetabular components was 92.7% (95% confidence interval (CI) 88.7 to 96.7) at ten years, 67.1% (95% CI 59.75 to 74.45) at 20 years and 53.2% (95% CI 45.3 to 61.1) at 25 years. For the femoral component the survival was 95.1% (95% CI 91.8 to 98.5) at ten years, 77.1% (95% CI 73.9 to 80.3) at 20 years and 68.2% (95% CI 60.7 to 75.8) at 25 years. The results indicate that the Charnley LFA remains a reasonable choice in the treatment of young patients and can serve for comparison with newer techniques and implants.

Cite this article: Bone Joint J 2013;95-B:1052–6.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 348 - 348
1 Jul 2011
Georgiades G Babis G Kourlaba G Hartofilakidis G
Full Access

We reported on the outcome of 84 Charnley low friction arthroplasties performed by one of us (GH), the period 1973 to 1984, in 69 patients, less than fifty-five years old, with osteoarthritis mainly due to congenital hip disease.

The patients were followed prospectively; clinically using the Merle D’Aubigné and Postel scoring system, as modified by Charnley and also radiographically.

At the time of the latest follow-up, thirty-seven hips had failed (44%). In thirty-two hips, twenty-eight acetabular and thirty femoral components were revised because of aseptic loosening (six of the femoral components were broken). Three hips were infected and converted to resection arthroplasty. In two more hips a periprosthetic femur fracture occurred three and ten years postoperatively and were treated with internal fixation. After a minimum of twenty-two years from the index operation, 37 original acetabular components and 36 original femoral components were in place for an average of 29 years. The probability of survival for both components with failure for any reason as the end point was 0.51 (95% confidence interval, 0.39 to 0.62) at twenty-five years when 35 hips were at risk.

These long term results can be used as a benchmark of endurance of current total hip arthroplasties performed in young patients, with OA mainly due to congenital hip disease.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 5 | Pages 601 - 607
1 May 2011
Hartofilakidis G Babis GC Georgiades G Kourlaba G

We studied the effect of trochanteric osteotomy in 192 total hip replacements in 140 patients with congenital hip disease. There was bony union in 158 hips (82%), fibrous union in 29 (15%) and nonunion in five (3%). The rate of union had a statistically significant relationship with the position of reattachment of the trochanter, which depended greatly on the pre-operative diagnosis. The pre-operative Trendelenburg gait substantially improved in all three disease types (dysplasia, low and high dislocation) and all four categories of reattachment position. A persistent Trendelenburg gait post-operatively was noticed mostly in patients with defective union (fibrous or nonunion). Acetabular and femoral loosening had a statistically significant relationship with defective union and the position of reattachment of the trochanter.

These results suggest that the complications of trochanteric osteotomy in total hip replacement for patients with congenital hip disease are less important than the benefits of this surgical approach.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 5 | Pages 580 - 586
1 May 2011
Hartofilakidis G Bardakos NV Babis GC Georgiades G

We retrospectively examined the long-term outcome of 96 asymptomatic hips in 96 patients with a mean age of 49.3 years (16 to 65) who had radiological evidence of femoroacetabular impingement. When surveillance commenced there were 17, 34, and 45 hips with cam, pincer, and mixed impingement, respectively. Overall, 79 hips (82.3%) remained free of osteoarthritis for a mean of 18.5 years (10 to 40). In contrast, 17 hips (17.7%) developed osteoarthritis at a mean of 12 years (2 to 28). No statistically significant difference was found in the rates of development of osteoarthritis among the three groups (p = 0.43). Regression analysis showed that only the presence of idiopathic osteoarthritis of the contralateral diseased hip was predictive of development of osteoarthritis on the asymptomatic side (p = 0.039).

We conclude that a substantial proportion of hips with femoroacetabular impingement may not develop osteoarthritis in the long-term. Accordingly, in the absence of symptoms, prophylactic surgical treatment is not warranted.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 6 | Pages 724 - 730
1 Jun 2008
Hartofilakidis G Georgiades G Babis GC Yiannakopoulos CK

We have evaluated the results of total hip replacement in patients with congenital hip disease using 46 cemented all-polyethylene Charnley acetabular components implanted with the cotyloplasty technique in 34 patients (group A), and compared them with 47 metal-backed cementless acetabular components implanted without bone grafting in 33 patients (group B). Patients in group A were treated between 1988 and 1993 and those in group B between 1990 and 1995. The mean follow-up for group A was 16.6 years (12 to 18) and the mean follow-up for group B was 13.4 years (10 to 16).

Revision for aseptic loosening was undertaken in 15 hips (32.6%) in group A and in four hips (8.5%) in group B. When liner exchange was included, a total of 13 hips were revised in group B (27.7%). The mean polyethylene wear was 0.11 mm/yr (0.002 to 0.43) and 0.107 mm/yr (0 to 0.62) for groups A and B, respectively. Polyethylene wear in group A was associated with linear osteolysis, and in group B with expansile osteolysis.

In patients with congenital hip disease, when 80% cover of the implant can be obtained, a cementless acetabular component appears to be acceptable and provides durable fixation. However, because of the type of osteolysis arising with these devices, early exchange of a worn liner is recommended before extensive bone loss makes revision surgery more complicated.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 188 - 188
1 Feb 2004
Gerostathopoulos N Georgiades G Sotiropoulos C Giannoulis F Goudelis G
Full Access

The purpose of this study was to evaluate the results of the surgical treatment of the thoracic outlet syndrome.

Between 1990–2002, 46 patients, 15 male and 31 female aged ranging from 23 to 49 years old (mean age 34 years) underwent decompressive surgery of the thoracic outlet syndrome. Some 9 patients required bilateral operations. Symptoms due to compression of neural elements were present in 23 patients, of vascular elements in 12 patients and of both elements in 11 patients. The duration of symptoms was less than 2 years in 25 patients and 2 to 6 years in 21 patients. Operations consisted of scalenectomy in 47 cases with brachial plexus neurolysis for neurogenic indication, release of the pectoralis minor muscle insertion in 5 cases and cervical rib resection in 3 cases.

The follow up period ranged from 1 to 12 years (mean 5 years). The results were classified as excellent with symptoms elimination in 27 cases, good with symptoms significant improvement in 19 cases and poor with symptoms persistent or aggravation in 9 cases. First rib resection in 4 patients with poor results and release of the pectoralis minor muscle insertion in 1 patient leaded to significant improvement of their symptoms. Some 90% of patient with symptoms less than 2 years had a successful result compared with only 76% in those with symptoms longer than 2 years. Complications included pneumothorax in one case and temporary phrenic nerve palsy in another case.

A selective surgical decompression of the thoracic outlet syndrome yields satisfactory results in appropriately selected patients.