Periprosthetic joint infection (PJI) represents the costliest complication in Orthopedics. Studies of mixing vancomycin to bone graft at Impaction Bone Grafting (IBG) have shown high local concentration for 3 weeks. 55 consecutive revisions PJI, age 68 (SD 10.9), (9 one-stage and 46 two-stage) were retrospectively analyzed. All cases were revised using IBG. Most cases had vancomycin mixed in graft or added locally in joint. All had bone cement containing Gentamycin and Vancomycin. Follow up 2–16 years included clinical Merle d'Aubigne-Postel score, radiology and laboratory tests. We analyzed surgical time, bleeding, hospitalization time, infection eradication and prosthetic survival for one- and two-stage revision procedures. One patient was lost to follow up and 6 died (2 one- and 4 2-stage) before 2 years. Values are mean and SD. Analyses done by students Introduction
Patients and methods
