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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_11 | Pages 25 - 25
7 Jun 2023
Unsworth R Barrow J As-Sultany M Hastie G Siney P Board T Divecha H
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Mortality following revision hip surgery for periprosthetic fracture (PPF) has been reported to be as high as 60% at 5 years. The aim of this study was to determine the mortality rate for PPF revisions, compared to revision for aseptic loosening or infection at our tertiary referral centre.

Revision arthroplasty procedures performed for PPF, aseptic loosening or infection between January 2014 and December 2015 at our institution were identified using a prospectively collected PPF referral database and locally collected NJR data. Comparisons were made between the 3 groups for baseline demographics, admission to higher-level care, length of stay, complications, and Kaplan-Meier failure (mortality) at 1 & 5 years post-operative (with log-rank test for equality).

There were 37 PPF, 71 infected and 221 aseptic revisions. PPF had a higher proportion of females (65% vs. 39% in infection and 53% in aseptic; p = 0.031) and grade 3 and 4 ASA patients (p = 0.006). Median time to surgery from injury for PPF was 8 days (95% CI, 6–16). Single-stage procedures were performed in 84% of PPF, 42% of infection and 99% of aseptic revisions (p < 0.001). 19% of PPF revisions required HDU admission, 1% in the aseptic group and none in the infection group (p<0.001). Median length of stay was significantly different (PPF 10; infection 14; aseptic 8 days (p < 0.001). The Kaplan-Meier estimate of 1-year mortality were: PPF = 0%; infection = 2.8% (0.7–11.1%); aseptic = 0.9% (0.2–3.5%). 5-year mortality estimates were: PPF = 17.1% (8–34%), infection = 8.7% (4–18.3%), aseptic = 12% (8.4–17%). Log-rank test of equality was not significant, p=0.833.

Despite the PPF group having an average delay to surgery of 8 days, higher ASA grades and more admissions to HDU there was no significant difference in mortality rates between the groups at 1 and 5 years postoperatively. Using a coherent MDT approach with dedicated healthcare professionals this service demonstrates a low post operative mortality rate which merits further investment and development.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 34 - 34
1 Aug 2021
Ramavath A Leong J Siney P Kay P Divecha H Board T
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Principles of bone preservation and restoration of biomechanical alignment should be followed during revision total hip arthroplasty (THA). Where possible, conservative femoral revision techniques and even reconstructive de-escalation involving using primary stems should be considered. This study aims to investigate the outcome of patients who have undergone conservative femoral revision THA in our Institution.

We retrospectively identified patients from our Institution's revision arthroplasty database who had cemented, or un-cemented primary stems implanted during revision THA of a previous stemmed femoral implant. Our primary outcome measure was all-cause re-revision THA with a secondary outcome measure of improvement in Oxford hip score (OHS). Radiographic evidence of stem loosening and post-op complications were recorded.

Between 02/12/2014 to 12/12/2019, there were 226 patients identified with a mean follow up of 2 years (1–5 years). The majority of cases were represented by Paprosky type 1 (63%) and type 2 (25%) femoral defects. There were 45 patients (20%) who underwent impaction bone grafting (IBG) and 43 patients (19%) who had a cement in cement (CinC) femoral revision and cemented primary stem in 137 (60%), 1 uncemented stem with no IBG or CinC revision. Kaplan Meier survival for all-cause re-revision THA was 93.7% (95% CI: 88.3 – 100) at 3 years. The reasons for re-revision included 4 periprosthetic fractures, 4 dislocations, 1 deep infection, 1 loosening of femoral component and 1 loosening of acetabular component. Pre- and post-operative OHS scores were available in 137 hips (60%) with a mean improvement of 13. Radiographic review revealed 7% of cases with evidence of loosening in 1 or more Gruen zones.

Our early results support the use of conservative femoral revision THA techniques where appropriate, with low complication and re-revision rates. Revisions using primary femoral components, where appropriate, should be considered in surgical planning to avoid unnecessary reconstructive escalation.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 39 - 39
1 Aug 2021
Rajan A Leong J Singhal R Siney P Shah N Board T
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Trabecular metal (TM) augments are designed to support an uncemented socket in revision surgery when adequate rim fit is not possible. We have used TM augments in an alternative arrangement, to contain segmental defects to facilitate impaction bone grafting (IBG) and cementation of a cemented socket. However, there is a paucity of literature supporting the use of this technique. We present one of the largest studies to date, reporting early outcomes of patients from a tertiary centre.

A single-centre retrospective analytical study of prospectively collected data was performed on patients who had undergone complex acetabular reconstruction using TM augments, IBG and a cemented cup. All patients operated between 2015 and 2019 were included. We identified 105 patients with a mean age of 74yrs. The mean follow-up was 2.3 years(1–5.5yrs). Our primary outcome measure was all-cause revision of the construct. The secondary outcome measures were, Oxford hip score (OHS), radiographic evidence of cup migration/loosening and post-op complications.

Eighty-four out of 105 patients belonged to Paprosky grade IIb, IIc or IIIa. Kaplan-Meier survivorship for all-cause revision was 96.36% (CI, 90.58–100.00) at 2 years with 3 failures. Two were due to early infection which required two-stage re-revision. The third was due to post-operative acetabular fracture which was then re-revised with TM augment, bone graft and large uncemented cup. Pre-op and post-op matched OHS scores were available for 60 hips(57%) with a mean improvement of 13 points. Radiographic analysis showed graft incorporation in all cases with no evidence of cup loosening. The mean vertical cup migration was 0.5mm (Range −5 to 7mm). No other complications were recorded.

This study shows that reconstruction of large acetabular defects during revision THA using a combination of TM augments to contain the acetabulum along with IBG to preserve the bone stock and a cemented socket is a reliable and safe technique with low revision rates and satisfactory clinical and radiographic results. Long term studies are needed to assess the possibility of preservation and regeneration of bone stock.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_6 | Pages 21 - 21
1 May 2019
Syam K Saraogi A Siney P Jones H Purbach B Nagai H Kay P
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Background

Revision total hip arthroplasty (THA) is a challenging scenario following complex primary THA for developmental dysplasia of hip (DDH). This study envisages the long-term outcomes of revision DDH and the role of lateral structural support in socket fixation in these young patients who may require multiple revisions in their life-time.

Materials and methods

Hundred and eighteen consecutive cemented revision THAs with minimum follow up of 5 years following primary diagnosis of DDH operated by a single unit between January 1974 and December 2012 were analysed for their clinical and radiological outcomes.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 11 - 11
1 Jan 2018
Saraogi A Lokikere N Siney P Nagai H Purbach B Raut V Kay P
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Introduction: Revision hip arthroplasty for aseptic loosening of femoral component is successfully treated with impaction bone grafting technique. Owing to easier technique and shorter operative time, distally fixed non-cemented long stems have gained popularity in the present era. However, use of long stems could make subsequent re-revision difficult due to further bone loss. The standard length stem has been often critiqued due to apprehension of peri-prosthetic fracture.

This study aims to determine the long-term outcomes of the impaction bone grafting of the femur for aseptic loosening in revision hip arthroplasty using standard length C-stems. 168 total hip revisions of 162 patients with impaction bone grafting and cemented standard C-stem (done with standardized technique) between 1995 and 2008 at a tertiary referral centre were included. Revisions for infection and segmental bone defects were excluded.

Mean follow-up of the 168 revision hips was 10.5 years (range 5 – 19.1 years). 14 patients (8.3%) were re-revised, reasons being, persistent deep infection (1.8%), repeated dislocations (1.2%), cup loosening (4.8%) and stem loosening (1.2%). Only 1 patient (0.6%) was re-revised due to stem loosening alone. No peri-prosthetic fractures (intra-operative or post-operative) or stem breakage were identified.

Use of standard stem length in hip revisions with impaction bone grafting does not increase the risk of peri-prosthetic fractures, instead, reconstitutes the bone stock. This questions the conventional principle of bypassing the distal cavitation of femur by 2 cortical diameters with the use of long stem. In our experience, a good proximal femur support is key to performance of standard length cemented stems in revision for aseptic loosening irrespective of grade of distal cavitation for cavitatory defects of femur when treated with impaction bone grafting.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 29 - 29
1 Jun 2016
Purbach B Siney P Jones HW Kay P Wroblewski B
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Introduction

Primary hip replacement in young active patients is on the increase. Due to the demands set by the patient, implants used in this patient group should have a proven long-term clinical and radiological outcome. We report our results in patients under the age of 50 using the C-Stem femoral component – a cemented triple tapered polished stem.

Methods

Since the C-stem femoral component was introduced into clinical practice in 1993, 6906 C-stems have been used in primary hip replacements at our hospital. In this group, 896 patients were under the age of 50 at the time of surgery. We report the first 300 consecutive C-stems from this group. The surgical technique of using a bone block to allow subsidence and clearing of the calcar to increase loading of the proximal femur medially was routinely used together with a femoral cement gun and pressurizer.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 40 - 40
1 Jun 2016
Johal S Siney P Wroblewski B Purbach B Board T Jones HW
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Introduction

Large acetabular bone defects caused by aseptic loosening are common. Reconstruction of large segmental defects can be challenging. Various implants and operative techniques have been developed to allow further acetabular revision in cases where bone stock is poor. Reconstitution of bone stock is desirable especially in younger patients. The aim of the study was to review the clinical and radiological results of hip revision with structural acetabular bone grafts using fresh frozen allograft and cemented components.

Method

Between 1990 and 2014, 151 first time revisions for aseptic acetabular loosening with acetabular reconstruction with a fresh frozen structural allograft and cemented components were performed at our hospital.

Graft dimensions, number of screws used and socket coverage by the graft were measured on the post-operative AP radiograph.

Follow-up radiographs were analysed for socket loosening, quality of graft union, graft and graft resorption.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_12 | Pages 43 - 43
1 Nov 2015
Rajpura A Wroblewski B Siney P Board T Jones HW
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Introduction

Cross linked polyethylene (XLPE) has gained popularity as a bearing surface of choice for younger patients despite only medium term results being available for wear rates. Concern remains regarding the long-term stability and durability of these materials. In order to address these issues we present the longest radiological and clinical follow-up of XLPE.

Patients/Materials & Methods

Since 1986, we have prospectively studied a group of 17 patients (19 hips) that underwent a cemented Charnley low friction arthroplasty using a combination of 22.225mm alumina ceramic femoral head, a modified Charnley flanged stem and a chemically cross-linked polyethylene cup. We now report the 28 year clinical and radiological results.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_12 | Pages 51 - 51
1 Nov 2015
Highcock A Siney P Wroblewski B Jones HW Raut V
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Introduction

Severe osteolysis of the femur secondary to aseptic loosening in hip arthroplasty, remains a difficult revision scenario. Multiple techniques have been developed to aid the surgeon, including restoration of bone stock with impaction bone grafting or strut allografts, various distal fixation prostheses and mega-prostheses. Cemented femoral components, with integration of the cement into the cavitations, has largely fallen out of favour. We examined the long-term outcomes with this technique.

Patients/Materials & Methods

Between 1977 and 1990, 109 patients had a cemented stem revision (without bone grafting) for severe femoral osteolysis in the absence of infection. Severe osteolysis was defined as cavitation in a minimum of 4 Gruen zones. Follow-up included functional scoring, radiological assessment and any complications. Further revision and survivorship analysis for stem failure or aseptic loosening of the femoral component were recorded.