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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_3 | Pages 8 - 8
1 Apr 2019
Kiran M Oikonomidis L AlMutani M Armstrong C Kumar G Peter V
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Background

Modularity in total hip replacement(THR) enables precise recreation of native hip biomechanics. However, there have been concerns about raised metal ion levels with increased number of interfaces. We present the 3 year results of ML taper with Kinectiv technology(MLKT), a modular neck uncemented stem. This system has modular neck options, but has only one [0] head in various diameters.

Methods

97 hips in 97 patients with a MLKT stem and Continuum socket were included in this prospective study. Harris hip score, Oxford hip scores (HHS and OHS) and yearly blood Cobalt(Co), Chromium(Cr) and Titanium(Ti) were recorded. The primary end point was revision for any reason. Paired t- test was used to assess improvement in functional scores.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_17 | Pages 23 - 23
1 Nov 2017
Kiran M Lacey A Awad M Peter V
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Introduction

It is standard practice to send samples for microbiological and histological analysis during revision surgery in suspected prosthetic joint infection. The aim of our study was to analyse the utility of histology in decision making in these patients.

Methods

We performed a retrospective review of all revision hip arthroplasty patients between from September 2013 and August 2016 from the hospital database. We analysed the results of aspiration, culture and sensitivity, histology from intra-operative samples and inflammatory markers. Diagnostic utility statistics were performed.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_13 | Pages 13 - 13
1 Jun 2016
Shivarathre D Croitoru C Dhotare S Rashid F Armstrong C Kapoor B Peter V
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High failure rates have been associated with large diameter metal-on-metal total hip replacements (MoM THR). However there is limited literature describing the outcomes following the revision of MoM THR for adverse local tissue reaction (ALTR).

A total of 98 large diameter MoM THRs underwent revision for ALTR at our institution. The data was obtained from the clinical records and included the demographics, intra-operative findings of ALTR and post-operative complications. Any subsequent procedures and re-revision for any reason was analysed in detail. The clinical outcome was measured using functional outcome scores using the Oxford hip score (OHS), Western Ontario and McMaster Universities osteo-arthritis index (WOMAC) score and Short Form (SF12).

The mean age of the patients at the time of revision was 58.2 yrs. At a mean follow-up of 3.9 years (1.0 to 8.6) from revision for ALTR, there were 15 hips (15.3 %) with post-operative complications and 8 hips (8 %) requiring re-revision. The Kaplan–Meier five-year survival rate for ALTR revision was 91 % (95% confidence interval 78.9 to 98.0). There were no statistically significant predictors of re-revision. The rate of postoperative dislocation following revision was 9.2% (9 hips). The post-operative functional outcome depends on the intra-operative findings of tissue destruction secondary to ALTR.

The short term results following revision of large diameter MoM THR for ALTR are comparable with other reports in the literature. The use of constrained liners reduces the incidence of post-operative dislocation. There is an increased risk of postoperative instability following revision THR for ALTR. Early identification and intervention seems to be the logical approach in the management of patients with ALTR.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_13 | Pages 7 - 7
1 Jun 2016
Mahmood A Sawalha S Borbora A Kumar G Peter V
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The effectiveness of intravenous tranexamic acid (TA) in reducing blood loss and transfusion requirements during total hip replacement (THR) is well recognised. The aim of this study was to assess the effectiveness of a fibrin sealant in comparison to intravenous TA and a control group.

We prospectively studied 270 patients with primary hip osteo-arthritis who underwent a straight forward THR between February 2012 and September 2013. The first 70 patients acted as the control group. The next 100 consecutive patients received fibrin sealant spray before closure and the last 100 patients received 1g TA on induction. Demographic data, comorbidities, surgical time, surgeon grade, anaesthetic type, haemoglobin drop post-operative and transfusion requirements were analysed using one-way ANOVA.

The demographic characteristics, surgical time, surgeon grade, anaesthetic type and pre-operative haemoglobin of the 3 groups were comparable. Both fibrin sealant and intravenous TA were effective in reducing blood loss during THR (15%, p = 0.04 & 22.5%, p = 0.01, respectively), when compared to the control group. However, neither treatment was found to be superior to the other in preventing blood loss p = 0.39. Tranexamic acid was superior to fibrin sealant in decreasing allogeneic transfusion requirements (0% vs 10%, p = 0.05). The LOS was significantly shorter in the tranexamic acid group than fibrin sealant group and in the fibrin sealant group compared with control group. There was no significant difference between the groups with regards to proportion of patients with wound leaking problems. No other complications (e.g. VTE) were encountered

Both fibrin sealant and intravenous tranexamic acid were effective in reducing blood loss. However, tranexamic acid use reduced post-operative transfusion requirements.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 310 - 310
1 Dec 2013
Frostick S Roebuck M Davidson J Santini A Peter V Banks J Williams A Wang H Thachil J Jackson R
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Introduction:

Wear debris from articulating joint implants is inevitable. Small debris particles are phagocytosed by macrophages. Larger particles initiate the fusion of many macrophages into multi-nucleated giant cells for particle encasement. Macrophages are recruited into inflamed tissues from the circulating monocyte population. Approximately 10% of white blood cells are monocytes which after release from the bone marrow circulate for 2–3 days, before being recruited into tissues as inflammatory macrophages or undergoing apoptosis. Circulating MRP8/14 (S100A8/A9) is a measure of monocyte recruitment, part of the monocyte-endothelial docking complex, and shed during monocyte transmigration across the endothelium. The higher the S100A8/A9 the more monocytes being recruited giving an indirect measure of debris production.

Methods:

2114 blood samples were collected from arthroplasty patients with hip or knee osteoarthritis (primary, post-traumatic and secondary), 589 before their primary arthroplasty, 1187 patients > 1 year post-arthroplasty, 101 patients before revision for aseptic loosening and 237 patients >1 year post-revision. Plasma S100A8/A9 was measured using BMA Biomedicals Elisa kit, normal levels in health adults are 0.5–3 mg/ml. Joint specific scores, WOMAC knee or Oxford Hip adjusted to percent of maximum, together with SF-12 were completed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 64 - 64
1 Mar 2012
Peter V Joshi Y George H Bass A
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Introduction

Some patients with Cerebral Palsy who had a de-rotation osteotomy performed for correction of excessive anteversion had persistence of internal foot progression even after surgery. Potential causes which have been implicated include: weak hip abductors, spasticity of the anterior fibres of the gluteus medius, hip adductor spasm and persistent femoral anterversion. The aim of this study was to see if there is any relationship between significant abductor weakness [less than Grade III: MRC] and persistence of internal foot progression.

Methods

We included all ambulatory patients with cerebral palsy who had had a derotation osteotomy between the periods of 2000-2005, who had also had a pre and post operative gait analysis, assessment of anteversion [Gage Test], hip range of motion and muscle charting.

There were 12 patients [17 hips, 5 bilateral] with an average age of 13. Seven were diplegic, two hemiplegic and three had asymmetric diplegia. Data was assessed using SPSS13.0. The Spearman Co-relation Coefficient was used to test if there was any correlation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 28 - 28
1 Feb 2012
Devalia K Peter V Braithwaite I
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The availability and usage of portable image intensifiers has revolutionised routine orthopaedic practice. Many procedures have become simpler, easier, less invasive and less time-consuming. Extensive use of fluoroscopy can, however, result in significant radiation exposure to operating staff. An accumulated dose of 65 (Sv after multiple exposures has been reported to increase the risk of thyroid cancer many years later. Previous studies have shown that it is possible to exceed this dose during various orthopaedic procedures. Though thyroid shields are extensively available most orthopaedic surgeons do not use them. The present study was aimed at measuring the scattered dose to thyroid during DHS/IMHS for neck of femur fractures and IM nailing for long bone fractures and thereby emphasise the need for operating theatre personnel to wear a thyroid shield.

A prospective study of 32 consecutive procedures was carried out. The EDD Unfors dosimeter was used to measure the tissue specific exposure dose to thyroid. Measurements were also obtained from the mobile C-arm fluoroscope unit, which calculated the total number of images and the total dose and duration of radiation for each procedure. Other factors including the grade of surgeon, the total number of theatre personnel wearing the lead gown and/or the thyroid shield and the duration of surgery were also recorded.

In 32 procedures, the dose of 65 (Sv was exceeded 13 times; 8 times during DHS/IMHS and 5 times during IMN. The average thyroid dose was 142 (Sv during IMN and 55 (Sv during DHS. Only 9 of 223 (4%) theatre personnel were using a thyroid shield in spite of its availability. The results suggest that the thyroid is frequently exposed to potentially harmful radiation during these procedures. Strict inclusion of a thyroid shield as a part of routine radiation protection is recommended.