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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_3 | Pages 28 - 28
1 Mar 2021
El-Hawary R Padhye K Howard J Ouellet J Saran N Abraham E Manson N Peterson D Missiuna P Hedden D Alkhalife Y Viswanathan V Parsons D Ferri-de-Barros F Jarvis J Moroz P Parent S Mac-Thiong J Hurry J Orlik B Bailey K Chorney J
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Proximal junctional kyphosis (PJK) is defined as adjacent segment kyphosis >10° between the upper instrumented vertebrae and the vertebrae 2 levels above following scoliosis surgery. There are few studies investigating the predictors and clinical sequelae involved with this relatively common complication. Our purpose was to determine the radiographic predictors of post-op PJK and to examine the association between PJK and pain/HRQOL following surgery for AIS.

The Post-Operative Recovery after Scoliosis Correction: Home Experience (PORSCHE) study was a prospective multicenter cohort of AIS patients undergoing spinal fusion surgery. Pre-op and minimum 2 year f/u scoliosis and sagittal spinopelvic parameters (thoracic kyphosis–TK, lordosis–LL, pelvic tilt-PT, sacral slope-SS, pelvic incidence-PI) were measured and compared to numeric rating scale for pain (NRS) score, SRS-30 HRQOL and to the presence or absence of PJK (proximal junctional angle >100). Continuous and categorical variables were assessed using logistic regression and binomial variables were compared to binomial outcomes using chi-square.

163 (137 females) patients from 8 Canadian centers met inclusion criteria. At final f/u, PJK was present in 27 patients (17%). Pre-op means for PJK vs No PJK: Age 14.1 vs 14.7yr; females 85 vs 86%; scoliosis 57±22 vs 62±15deg; TK 28±18 vs 19±16deg ∗, LL 62±11 vs 60±12deg, PT 8±12 vs 10±10deg, SS 39±8 vs 41±9deg, PI 47±14 vs 52±13deg, SVA −9±30 vs −7±31mm. Final f/u for PJK vs No PJK: Scoliosis 20±11 vs 18±8deg, final TK 26±12 vs 19±10deg∗, LL 60±11 vs 57±12deg, PT 9±12 vs 12±13deg, SS 39±9 vs 41±9deg, PI 48±17 vs 52±14deg, SVA −23±26 vs −9±32mm∗. Significant findings: Pre-op kyphosis >40deg has an odds ratio (OR) of 4.41 (1.50–12.92) for developing PJK∗. The presence of PJK was not associated with any significant differences in NRS or SRS-30. ∗denotes p<0.05.

This prospective multicenter cohort of AIS patients demonstrated a 17% risk of developing PJK. Pre-op thoracic kyphosis >40deg was associated with the development of PJK; however, the presence of PJK was not associated with increased pain or decreased HRQOL.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_29 | Pages 40 - 40
1 Aug 2013
Firth G Moroz P Kingwell S
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Purpose:

Non-contiguous spinal injury can add significant complexity to the diagnosis, management and outcome in children. There is very little in the paediatric literature examining the nature, associated risk factors, management and outcomes of non-contiguous spinal injuries. The objective is to determine the incidence and clinical characteristics of non-contiguous spinal injuries in a paediatric population. The secondary objective is to identify high risk patients requiring further imaging to rule out non-contiguous spinal injuries.

Methods:

All children up to 18 years of age with a spinal injury, as defined by ICD-09 codes at one paediatric trauma hospital were included (n=211). Data for patient demographics, mechanism of injury, spinal levels involved, extent of neurologic injury and recovery, associated injuries, medical complications, treatment and outcome were recorded.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 177 - 177
1 Sep 2012
Carsen S Beaulé PE Willis B Ward L Rakhra K Dunlap H Moroz P
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Purpose

The importance of femoral head-neck morphology in the development of early hip osteoarthritis is recognized in femeroacetabular impingement (FAI), however no studies have examined FAI morphology in the developing hip, i.e. pre-closure of the proximal femoral physis. We developed a pilot project to study prevalence of CAM-type FAI hip morphology in both the pre- and post-closure proximal femoral physes of asymptomatic children using MR-imaging. We also examined biologic markers possibly related to FAI etiology, including Vitamin D metabolites, BMI, family history, and activity levels.

Method

Recruitment included volunteers with asymptomatic lower extremities, and either pre- or post-closure of the proximal femoral physis. Males were 10–12 years (pre-closure) or 15–18 years (post-closure); females were 8–10 years or 14 18 years. Phlebotomy and urine sampling were used to assess metabolic markers. MRI of bilateral hips and a clinical exam including hip impingement tests were conducted. MR imaging assessment was independent and blinded and recorded using established parameters including alpha angles measured at both the 3:00 (anterior head-neck junction) and 1:30 (antero-superior head-neck junction) radial image positions.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 82 - 82
1 Mar 2008
Moroz P Benoit PB Emans J Hresko T Kasser J
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Operative treatment of flexion-distraction fractures of the thoraco-lumbar spine in children and adolescents may be the preferred approach to the management of this fracture.

In this retrospective review of thoraco-lumbar flexion-distraction spine fractures at a paediatric level One trauma center we compared outcomes (fusion and loss of reduction) of operatively and non-operatively managed patients. Twenty cases of thoraco-lumbar and lumbar region flexion-distraction fractures were identified. Patients were grouped by non-operative versus operative and three Cobb angles were recorded from radiographs of each patient: one taken at the time of fracture, one at initiation of treatment, and the last at final follow-up. Union rate and changes in angular deformity was analysed using Chi square analysis and Fischer’s exact test.

Patients included eleven males and nine females with an average age of 13.9 (range 6 – 17). Average length of follow-up was 5.4 years. Eighty-five percent of cases involved motor-vehicle crashes with seventy percent wearing some form of seatbelt. Twenty percent had a neurological injury, all having surgery as initial management. All (100.0%) patients initially treated surgically healed with an average loss of lordosis of 7.5°. Five of the seven (71.4%) in the non-operative group developed non-union with instability and an average loss of 33.2° of reduction. All five non-unions went on to successful surgical fusion. Flexion-distraction fractures were 29.9 times more likely to heal successfully if having initial surgery (Odds ratio = 29.9, 95% C.I. 2.1 to 410.9).

Non-operative management leads to an unacceptably high rate of non-union and we recommend primary surgical management of all paediatric thoraco-lumbar flexion-distraction injuries.