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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_5 | Pages 31 - 31
23 Apr 2024
Bandopadhyay G Lo S Yonjan I Rose A Roditi G Drury C Maclean A
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Introduction

The presence of pluripotent mesenchymal cells in the periosteum along with the growth factors produced or released following injury provides this tissue with an important role in bone healing. Utilising this property, vascularised periosteal flaps may increase the union rates in recalcitrant atrophic long bone non-union. The novel chimeric fibula-periosteal flap utilises the periosteum raised on an independent periosteal vessel, thus allowing the periosteum to be inset freely around the osteotomy site, improving bone biology.

Materials & Methods

Ten patients, with established non-union, underwent fibula-periosteal chimeric flaps (2016–2022) at the Canniesburn Plastic Surgery Unit, UK. Preoperative CT angiography was performed to identify the periosteal branches. A case-control approach was used. Patients acted as their own controls, which obviated patient specific risks for non-union. One osteotomy site was covered by the chimeric periosteal flap and one without. In two patients both the osteotomies were covered using a long periosteal flap.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_16 | Pages 32 - 32
1 Oct 2014
Motesharei A Rowe P Blyth M Jones B MacLean A Anthony I
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Unicompartmental knee arthroplasty (UKA) has been gaining popularity in recent years due to its perceived benefits over total knee arthroplasty (TKA), such as greater bone preservation, reduced operating-room time, better post-operative range of motion and improved gait. However there have been failures associated with UKA caused by misalignment of the implants that have lead to revisions. To improve the implant alignment a robotic guidance system called the RIO Robotic Arm has been developed by MAKO Surgical Corp (Ft. Lauderdale, FL), which is designed to give improved accuracy compared to traditional UKA using cutting jigs and other manual instrumentation.

The University of Strathclyde in association with Glasgow Royal Infirmary has undertaken the first independent RCT trial of the MAKO system against the Oxford unicompartmental knee arthroplasty – a conventional UKA used in the UK. Motion analysis was used in order to obtain a quantitative assessment of their movement. The results from a total of 51 patients (23 MAKO, 28 Oxford) that underwent a one year post-operative biomechanical assessment were investigated.

Motion analysis showed that during level walking the MAKO group achieved a higher knee excursion during the highest flexion portion of the weight bearing stage of the gait cycle (foot-strike to mid-stance) compared to the Oxford group (18.6° and 15.8° respectively). This difference was statistically significant (p-value = 0.03). Other knee excursion values that were compared were from mid-stance to terminal stance, and overall knee flexion. No statistically significant differences were seen in either of these measurements. A subsequent comparison of both MAKO and Oxford groups with a matched normal cohort (50 patients), demonstrated that there wasn't a statistically significant difference between the MAKO group and the normal knees during mean knee excursion from foot-strike to mid-stance (18.6° and 19.5° respectively, p-value 0.36). However the Oxford group, with a lower knee excursion was found to be significantly different to our normal control group (15.8° and 19.5° respectively, p-value < 0.001).

This suggests that the robotic-assisted knees behaved more similarly to normal gait during this phase of the gait cycle than those of the conventional group. While significant differences in gait were found between the Oxford and MAKO groups, further work is required to determine if this results in improved knee function that is perceptible to the patient.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_28 | Pages 69 - 69
1 Aug 2013
Smith J Blyth M Jones B MacLean A Rowe P
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Total knee arthroplasty (TKA) has been established as a successful procedure for relieving pain and improving function in patients suffering from severe knee osteoarthritis for several decades now. It involves removing bone from both the medial and lateral compartments of the knee and sacrificing one or both of the cruciate ligaments. This in turn is likely to have an impact on the patients' functional outcome. In subjects where only one compartment of the knee joint is affected with osteoarthritis then unicondylar knee arthroplasty (UKA) has been proposed as an alternative procedure to TKA. This operation preserves the cruciate ligaments and removes bone only from the affected side of the joint. As a result there is the possibility of an improved functional outcome post surgery. UKA has been associated with faster recovery, good functional outcome in terms of range of motion and it is bone sparing compared to TKA. However, the biggest obstacle to UKA success is the high failure rates.

The aim of this study was to compare the functional outcome of computer navigated TKA (n=60) and UKA (n=42) patients 12 month post operation using flexible electrogoniometry. Flexible electrogoniometry was used to investigate knee joint kinematics during gait, slopes walking, stair negotiation, and when using standard and low chairs. Maximum, minimum and excursion knee joint angles were calculated for each task.

The biomechanical assessment showed statistically significant improvements in the knee kinematics in terms of maximum (p<0.0004) and excursion (p<0.026) knee joint angles in the UKA patient group compared to the navigated TKA group for each of the functional tasks. There was no statistically significant difference between the minimum knee joint angles during these functional tasks (p>0.05).

Therefore, UKA patients were showed to have a significantly better functional outcome in terms of the maximum knee joint angle during daily tasks. A limitation of this study is that it compares two cohorts rather than two randomised groups. It is expected that UKA patients will have a better functional outcome. Our results suggest that for patients with less severe knee osteoarthritis, UKA may offer a better functional outcome than the more common surgical option of TKA. The recent advancements in computer assisted and robotic assisted knee arthroplasty has the possibility to improve the accuracy of UKA and therefore led to the increase in confidence and in usage in a procedure which has the potential to give patients a superior functional outcome.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_28 | Pages 91 - 91
1 Aug 2013
Motesharei A Rowe P Smith J Blyth M Jones B MacLean A
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Unicompartmental knee arthroplasty (UKA) has been gaining popularity in recent years due to its perceived benefits over total knee replacements, such as greater bone preservation, reduced operating-room time, better postoperative range of motion and improved gait. However there have been failures associated with UKA caused by misalignment of the implants.

To improve the implant alignment a robotic guidance system called the RIO Robotic Arm has been developed by MAKO Surgical Corp (Ft. Lauderdale, FL). This robotic system provides real-time tactile feedback to the surgeon during bone cutting, designed to give improved accuracy compared to traditional UKA using cutting jigs and other manual instrumentation.

The University of Strathclyde in association with Glasgow Royal Infirmary has undertaken the first independent Randomised Control Trial (RCT) of the MAKO system against the Oxford UKA – a conventional UKA used in the UK. The trial involves 139 patients across the two groups.

At present the outcomes have been evaluated for 30 patients. 14 have received the MAKO unicompartmental knee arthroplasty and 16 the Oxford UKA. Both groups were seen 1 year post-operatively. Kinematic data was collected while subjects completed level walking using a Vicon Nexus motion analysis system. Three-dimensional hip, knee and ankle angles were compared between the two arthroplasty groups.

Our initial findings indicate that hip and ankle angles show no significant statistical difference, however there is a significant difference (p < 0.05) in the knee angles during the stance phase of gait. Data shows higher angles achieved by the MAKO group over the Oxford.

It would appear from our early findings that the MAKO RIO procedure with Restoris implants gives at least comparable functional outcome with the conventional Oxford system and may prove once our full sample is available for analysis to produce better stance phase kinematics with a more active gait pattern than the conventional Oxford procedure.

Further work includes analysing the data obtained from the patients in a number of other activities. These include a full biomechanical analysis of ascending and descending a flight of stairs, sit to stand and a deep knee lunge. The high demand/high flexion tasks in particular may reveal if there's an advantage to using the MAKO procedure over the Oxford. If there is a direct correlation between alignment and patient function then this effect could be more significant in the more demanding patient tasks.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XIX | Pages 14 - 14
1 May 2012
Maclean A Howells N Blewitt N
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Scaphoid injuries remain a challenge in both diagnosis and subsequent management. Untreated scaphoid non-union leads to inevitable osteoarthritis. Non-unions are picked up via an established management pathway in out trust and treated surgically with a standardised technique of non-vascularised bone grafting and retrograde screw fixation. Patients that underwent primary screw fixation and grafting for scaphoid non-union between 2004-2008 were reviewed. These patients were followed up clinically and radiologically. They were assessed for time to union, complications, DASH score, patient satisfaction and return to work. In addition comparison was made between the use of Herbert screw and Twinfix screw fixation and between tricortical iliac crest graft and corticocancellous distal radial bone graft. Forty-two consecutive patients underwent surgery of which 35 (83%) were available for follow up. Mean follow up was 39 months (range 13-72). 31 (89%) patients had gone on to radiological union. Of those united the mean DASH score was 11. Mean time to union was 4.4 months (range 2-15 95% CI 3.3 – 5.5). 95% of patients were satisfied with their operation and would recommend it to a friend in the same situation. No significant difference in outcomes were identified between Herbert screw and Twinfix screw fixation or between iliac crest or distal radial bone grafting techniques. This study has shown encouraging results for an established protocol for management of scaphoid non-union. Outcomes are as a good as any published comparable series in the literature and provide further support to the use of this technique.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XII | Pages 17 - 17
1 Apr 2012
Maclean A Bannister G Murray J Lewis S
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Last minute cancellations of operations are a major waste of NHS resources. This study identifies the number of late cancellations at our elective orthopaedic centre, the reasons for them, the costs involved, and whether they are avoidable.

Last minute cancellations of operations in a 7-month period from January to July 2009 were examined.

172 cases out of 3330 scheduled operations were cancelled at the last minute (5.2%). Significantly more cancellations occurred during the winter months due to seasonal illness.

The commonest causes for cancellation in descending order of frequency were patient unfit/unwell (n=76, 44.2%), lack of theatre time (n=32, 18.6%), patient self cancelled/DNA (n=20, 11.6%), staff unavailable or sick (n=9, 5.2%), theatre or equipment problem (n=8, 4.7%), operation no longer required (n=8, 4.7%), administrative error (n=7, 4.1%) or no bed available (n=5, 2.9%). In 7 out of the 172 cancelled cases (4.1%) no cause was identified. 59.7% of the cases were potentially avoidable.

3.2% of Patients seen in the specialist pre-operative anaesthetic clinic (POAC) were cancelled at the last minute for being unfit or unwell, compared to 2.2% seen in the routine nurse led clinic. Last minute cancellations cost the hospital over £700,000 in 7 months.