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The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 11_Supple_A | Pages 36 - 41
1 Nov 2012
Aderinto J Lulu OB Backstein DJ Safir O Gross AE

Eighteen hip fusions were converted to total hip replacements. A constrained acetabular liner was used in three hips. Mean follow up was five years (two to 15). Two (11%) hips failed, requiring revision surgery and two patients (11%) had injury to the peroneal nerve. Heterotopic ossification developed in seven (39%) hips, in one case resulting in joint ankylosis. No hips dislocated.

Conversion of hip fusion to hip replacement carries an increased risk of heterotopic ossification and neurological injury. We advise prophylaxis against heterotropic ossification. When there is concern about hip stability we suggest that the use of a constrained acetabular liner is considered. Despite the potential for complications, this procedure had a high success rate and was effective in restoring hip function.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 26 - 26
1 Sep 2012
Zywiel MG Kosashvili Y Gross AE Safir O Lulu OB Backstein D
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Purpose

Infection following total knee arthroplasty is a devastating complication, requiring considerable effort on the part of the surgeon to eradicate the infection and restore joint function. Two-stage revision is the standard of care in the treatment of peri-prosthetic infection, using a temporary antibiotic-impregnated spacer between procedures. However, controversy remains concerning the use of static versus dynamic spacers, as well as the spacer material. The purpose of this study was to evaluate the clinical outcomes and complications of two-stage revision total knee arthroplasty in patients treated with a metal-on-polyethylene articulating spacer, as compared to those treated with a static antibiotic-impregnated cement spacer at the same centre.

Method

Twenty-seven knees in patients with a mean age of 65 years (range, 40 to 80 years) were treated with two-stage revision of an infected total knee arthroplasty using a metal-on-polyethylene dynamic prosthetic spacer fixed with antibiotic-impregnated cement. Clinical outcomes were evaluated using maximum active knee range of motion, as well as modified Knee Society knee scores and incidence of re-infection at a minimum one-year follow-up. The results were compared to those achieved at similar follow-up in 10 patients treated with a static cement spacer. Demographic profile as measured by age and gender, and pre-operative Knee Society scores and range of motion were similar between the two groups.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 559 - 560
1 Nov 2011
Raz G Safir O Lee P Lulu OB Backstein DJ Gross A
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Purpose: An Osteochondral defect in the knees of young active patients represents a challenge to the orthopedic surgeon. Early studies on allogenic cartilage transplantation showed this tissue to be immunologically privileged, showed fresh grafts to have hyaline cartilage, and surviving chondrocytes present several years after implantation.

Method: Since January 1978 until October 1995 we enrolled 72 patients in a prospective non-randomized study of fresh osteochondral allografts in our institute. Ten international patients which were lost to follow-up were excluded. The major indications for the procedure were: patients younger than 60 years of age having post-traumatic unipolar defects larger than three cm in diameter and one cm in depth.

Results: Sixty two patients, ages 11–57 (mean 28) were followed for 15–31 years (mean 20.4 years). The etiology for the osteochondral defect was traumatic injury to the knee in 41 patients (66%), Osteochondritis Dissecans in 15 patients (24%), and in six patients (10%) due to other pre-existing conditions. Twenty of the 62 grafts have failed, with five having graft removal and 15 converted to total knee replacement. Three patients died during the course of this study due to unrelated causes. The Kaplan-Meier survivorship analysis showed: 92%, 79%, 56%, and 49% graft survival at 10, 15, 20, and 25 years respectively, (median survival = 23 years). Patients with surviving grafts had good function, with a modified Hospital for Special Surgery score of an average 88 at 20 years or more following the allograft transplantation surgery.

Conclusion: Through this long term study the authors confirm the value of fresh osteochondral allografts as a long term solution for large articular defects in the knees of young patients. The improvement of patients’ outcome compared to the previous published results of our earlier studies could be attributed to improved surgical techniques and increasing expertise of the senior authors. We therefore recommend the use of fresh osteochondral allografts for treatment of large osteochondral defects in the distal femur of young and active patients.