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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_17 | Pages 3 - 3
24 Nov 2023
Dinh A Chatillon ED Ho R McNally M Dudareva M Scarborough M Jesuthasan G Escolà-Vergé L Lora-Tamayo J Mancheño-Losa M Thill P Giordano G Fourcade C Duran C Bonnet E Hascoet JL
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Aim

Prosthetic joint infection (PJI) due to Candida spp. is a severe complication of arthroplasty but is little reported. This study describes Candida PJI epidemiology, management, and outcome.

Method

We performed a retrospective, observational multinational study with support of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). Patients diagnosed with PJI due to Candida spp. between 1990 and 2021 were included. Demographic, clinical, laboratory, imaging, medical/surgical treatment, and outcome data were collected within a standardized database. Treatment failure was defined either as a Candida infection recurrence, superinfection, or death due to infection.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 1 - 1
1 Dec 2018
Wouthuyzen-Bakker M Sebillotte M Lomas J Kendrick B Palomares EB Murillo O Parvizi J Shohat N Reinoso JC Sánchez RE Fernandez-Sampedro M Senneville E Huotari K Allende JMB García AB Lora-Tamayo J Ferrari MC Vaznaisiene D Yusuf E Aboltins C Trebse R Salles MJ Benito N Vila A Del Toro MD Kramer T Petersdorf S Diaz-Brito V Tufan ZK Sanchez M Arvieux C Soriano A
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Aim

Late acute prosthetic joint infections (PJI) treated with surgical debridement and implant retention (DAIR) have a high failure rate. The aim of our study was to evaluate treatment outcome in late acute PJIs treated with DAIR versus implant removal.

Method

In a large multicenter study, late acute PJIs were retrospectively evaluated. Failure was defined as: PJI related death or the need for prosthesis removal or suppressive antibiotic therapy because of persistent or recurrent signs of infection. Late acute PJI was defined as < 3 weeks of symptoms more than 3 months after the index surgery.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 92 - 92
1 Dec 2018
Wouthuyzen-Bakker M Sebillotte M Lomas J Taylor A Palomares EB Murillo O Parvizi J Shohat N Reinoso JC Sánchez RE Fernandez-Sampedro M Senneville E Huotari K Allende JB Garcia-Cañete J Lora-Tamayo J Ferrari MC Vaznaisiene D Yusuf E Aboltins C Trebse R Salles M Benito N Vila A Del Toro MD Kramer T Petershof S Diaz-Brito V Tufan ZK Sanchez M Arvieux C Soriano A
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Aim

Debridement, antibiotics and implant retention (DAIR) is the recommended treatment for all acute prosthetic joint infections (PJI). However, the efficacy of DAIR and identification of risk factors for failure in patients with late acute PJI, is not well described.

Method

Patients diagnosed with late acute PJI between 2005 and 2015 were retrospectively evaluated. Late acute PJI was defined as the development of acute symptoms (≤ 3 weeks) occurring ≥ 3 months after arthroplasty. Failure was defined as: i) the need for implant removal, ii) infection related death, iii) the need for suppressive antibiotic therapy due to persistent signs of infection and/or iv) relapse or reinfection during follow-up.