Non-tuberculous mycobacterial (NTM) infection of the musculoskeletal tissue is a rare disease. An early and accurate diagnosis is often difficult because of the indolent clinical course and difficulty of isolating pathogens. Our goal was to determine the clinical features of musculoskeletal NTM infection and to present the treatment outcomes. A total of 29 patients (nine females, 20 males between 34 and 85 years old, mean age 61.7 years; 34 to 85) with NTM infection of the musculoskeletal system between 1998 to 2011 were identified and their treatment retrospectively analysed. Microbiological studies demonstrated NTM in 29 patients: the isolates were Mycobacterium intracellulare in six patients, M. fortuitum in three, M. abscessus in two and M. marinum in one. In the remaining patients we failed to identify the species. The involved sites were the hand/wrist in nine patients the knee in five patients, spine in four patients, foot in two patients, elbow in two patients, shoulder in one, ankle in two patients, leg in three patients and multiple in one patient. The mean interval between the appearance of symptoms and diagnosis was 20.8 months (1.5 to 180). All patients underwent surgical treatment and antimicrobial medication according to our protocol for chronic musculoskeletal infection: 20 patients had NTM-specific medication and nine had conventional antimicrobial therapy. At the final follow-up 22 patients were cured, three failed to respond to treatment and four were lost to follow-up. Identifying these diseases due the initial non-specific presentation can be difficult. Treatment consists of surgical intervention and adequate antimicrobial therapy, which can result in satisfactory outcomes.

Cite this article: Bone Joint J 2014;96-B:1561–5.

A seventy-five-year-old female patient presented with pain and deformity of her left leg of three days duration. Hybrid THRA has been done 11 years ago at her left hip for the treatment of osteoarthritis. Massive osteolysis and pathologic fracture were observed on plain radiograph (Fig. 1). Revision THRA using an allograft prosthesis composite (APC) was planned for solution of extensive bone loss of the proximal femur. Surgical exposure was performed through extended trochanteric osteotomy with the patient supine. Step-cut osteotomy was done at the remained proximal part of host femur to make match with the distal part of APC. Meticulous removal of granulation tissues and remaining cement was done. As Acetabular cup was stable, 60 mm sized high-walled polyethylene liner was exchanged. Calcar reconstruction prosthesis was cemented into a proximal femoral allograft measuring 15 cm and cement at the vicinity of the step-cut osteotomy was removed for later bony union at interface. After solid fixation of APC with cement, the distal half of APC was cemented with the host femur. Step-cut osteotomy was wired and autogenous bone grafts from the greater trochanter were added at the interface. Leg length and stability were rechecked using a standard necked 28 mm metal head and reduction was done stably. Greater trochanter was fixed over the trimmed proximal allograft with multiple wiring and paper-thin host femur was enveloped around the femoral allograft using absorbable sutures. Following insertion of the closed suction drainage drains, closure was done as routine fashion and healing of the wound was uneventful (Fig. 2). An abduction brace was applied post operatively for a period of four weeks. Crutch walking with partial weight bearing was started at four weeks and crutch protection was applied for a period of six months. Incorporation of allograft with the host bone was observed on two-year follow-up radiographs. At seven-year follow-up, the patient walks well with a mild limp, and Harris score is 90. We report on a seven-year follow-up case of revision THRA with APC with references (Fig. 3).

The posterior-stabilized knee prosthesis is designed specifically to provide the posterior stability to a knee arthroplasty when PCL is deficient or has to be sacrificed. Posterior dislocation of such prosthesis is rare but dreaded complication. There are several causes of postoperative dislocation such as malposition of the prosthesis, preoperative valgus deformity, a defect of the extensor mechanism and overwidening of the flexion gap. Posterior-stabilized rotating-platform mobile-bearing knee implants have been widely used to further improve the postoperative range of motion by incorporation of the post and cam mechanism to improve the posterior roll back during flexion and to overcome the wear and osteolysis problems due to significant undersurface micromotion of posterior-stabilized fixed-bearing knees. But, spin-out or rotatory dislocation of the polyethylene insert can occurs as result of excessive rotation of the rotating platform accompanied by translation of the femur on the tibia after mobile-bearing total knee arthroplasty, but that is very rare. Here, authors describe an unusual case of acute 180° rotatory dislocation of the rotating platform after posterior dislocation of a posterior-stabilized mobile-bearing total knee arthroplasty.

A 71-year-old male with knee osteoarthritis underwent a TKRA using posterior-stabilized mobile-bearing prosthesis. The posterior dislocation of the total knee arthroplasty occurred 5 weeks postoperatively(Fig. 1). We underwent closed reduction of posterior dislocated total knee arthroplasty resulting in a complete 180° rotatory dislocation of the rotating platform (Fig. 2). He was treated with open exploration and polyethylene exchange with a larger component.

This case illustrates that dislocation of a posterior-stabilized mobile-bearing total knee arthroplasty can occur with valgus laxity, cause 90° spin-out of the polyethylene insert and closed reduction attempts may contribute to complete 180° rotatory dislocation of the rotating platform. Special attention needs to be paid to both AP and lateral view to ensure that the platform is truly reduced and not just rotated 180° as was in this case.