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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 145 - 145
1 Jan 2016
Sato T Hattori Y Kida D Kaneko A
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Friction between bearing surfaces in Total Hip Arthroplasty has been a main target of applied tribology. MPC (2-Methacryloyloxyethyl phosphorylcholine) has a similar properties to those of cell membranes, and can reduce friction with fluid lubrication in wet environment. We have used crosslink polyethylene with MPC polymer coating for primary and revision THA since 2011.

We have examined 19 cases which were followed for more than two years. Sixteen cases for primary THA and three for revision THA, and 3 were male and 16 were female. Sixteen cases were osteoarthritis, one osteonecrosis of femoral head and two rheumatoid arthritis. Average age of patients at THA was 60.1 years old.

In the OR, we have experienced a very wet and slippery feeling on the bearing surface of polyethylene liner. Surface touch is similar to hard surface with oil or lotions. No PE wear were measured on the X-ray display and no infections and no fractures were occurred during follow up.

MPC polymer coating in THA can be useful for reduction of friction and generation of wear debris.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 167 - 167
1 Dec 2013
Sato T Kaneko A Ishikawa H Kida D
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Reducion of friction between bearing surfaces in Total Hip Arthroplasty is a main target of biological tribology. MPC (2-Methacryloyloxyethyl phosphorylcholine) has a similar properties to those of cell membranes, and can reduce friction with fluid luburication. We have used crosslink polyethylene with MPC polymer coating for primary and revision THA since 2011.

Eighty one cementless THA were performed with closslink polyethlene liner with MPC polymer in our hospital. We have examined 21 cases which were followed for more than one year. Eighteen cases for primary THA and three for revision THA, and 3 were male and 18 were female. Seventeen cases were osteoarthritis, two osteonecrosis of femoral head and two rheumatoid arthritis. Average age of patients at THA was 60.4 years old.

In the OR, we have experienced a very wet and slippery feeling on the bearing surface of polyethylene liner every time. Surface touch is similar to skin with lotions. No wear were measured on the X-ray display and no infections and no fractures were occurred during follow up.

MPC polymer coating in THA can be useful for reduction of friction and generation of wear debris.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 319 - 319
1 Mar 2013
Sato T Kaneko A Kida D
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Revision Total Hip Arthroplasty can be challenging in case of thin or fragile femur. Primary Bipolar Hip Prosthesis (BHP) is also difficult in severe osteoporosis case. We have used titanium alloy cementless stem with interlocking screws for revision THA since 2003, and primary BHP in senile case since 2007.

Thirty four cementless THA were performed with interlocking stem (27 S-LOCK and 7 Delta-LOCK) since 2007, and 26 cases were followed for more than one year. Two for primary THA and 24 for revision THA, 3 were male and 23 were female. Seven primary Bipolar Hip Prosthesis with interlocking screw stem for femoral neck fracture were also followed more than one year. All seven BHP cases were female.

Stress shielding in X-ray film were observed in 3 revision THA cases during follow up, but no pain were complained. No breakage of screws and stems were observed, and no infections and no fractures were occurred.

In case of loosened stem, long interlocking stem can bypass the weak point of femur after removal of cement or metal stem tip. Patients can walk immediately after revision THA or primary BHP.

Cementless interlocking stem in THA and BHP is useful for management of thin or fragile femoral cortex.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 160 - 160
1 Sep 2012
Sato T Kaneko A Kida D
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Infection and skin ulcer are major problems in Total Knee Arthroplasty (TKA) and Bipolar Hip Prosthesis (BHP). Sugar (sucrose) has been used for wound care in many countries because it absorbs fluid, stimulates granulation, and suppress growth of bacteria. Trafermin ∗∗∗∗∗ recombinant human basic fibroblast growth factor ∗∗∗∗∗ FGF ∗∗∗∗∗ accelerates granulation process and improves quality of wound healing. We have used sucrose and trafermin for treatment of infection after TKA and BHP.

Six infected TKA with skin ulcer and one infected BHP with fistula were treated with Trafermin and sugar. TKA were performed in four osteoarthritis and two rheumatoid arthritis, and BHP was for femoral neck fracture. Implants were removed in three cases because of deep infection. One was male and six were female, average age were 60.8 years old ranged 43 to 77. Follow-up period were one to 5 years. Four cases were related to MRSA. Sugar treatment were performed for two to 23 weeks, and Trafermin was sprayed once a day for two to 16weeks. In BHP case, sugar therapy was performed intermittently.

In two deep infected TKA cases, infection ceased in one to 4 month and revision TKA were performed. In other four TKA cases, infection were ceased in two to 16 weeks. In BHP case, fistula closed in three years.

Combination of Trafermin and sugar is useful for management of infection and skin ulcer after TKA and BHP


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 135 - 135
1 Mar 2010
Sato T Thukamoto M Kaneko A Kida D Eto Y
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Infection is one of major problems in Total Knee Arthroplasty (TKA) or Bipolar Head Prosthesis (BHP). We have used Calcium Phosphate Paste (CPP) for treatment of infected TKA and BHP, and followed up for minimum one year. CPP is a mixture of alpha Tri-Calcium Phosphate, Tetra-Calcium Phosphate, Calcium Hydrogen Phosphate and Hydroxyapatite. CPP harden in 10 minutes and its stiffness increases to maximum in 3 days.

Infected TKA were diagnosed in four osteoarthritis and four rheumatoid arthritis knees, and BHP infection were observed in two femoral neck fracture cases from 2001 to 2007. Two were male and eight were female, average age were 67.3 years old ranged 39 to 80. Follow-up period were one to 7 years. Six cases were MRSA infection, three MSSA, one was unidentified but diagnosed with clinical data. In TKA cases, CPP (10–12g) with vancomycin hydrochloride or tobramycin were filled on the back side of PMMA articulated surface spacers, and in BHP cases, CPP with antibiotics were filled in acetabulum. In all TKA cases, infection ceased in 2 to 4 month and revision TKA ware performed. One recurrence of infection was observed during follow up in BHP infection, and nine patients can walk with/without a cane. No venous thromboembolism were observed.

CPP filled in the space between articulated spacer and bone is gradually crashed and can release antibiotics during walking and ROM exercise. CPP with antibiotics is useful for the treatment after infected TKA and BHP.