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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 37 - 37
2 May 2024
Green J Malviya A Reed M
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OpenPredictor, a machine learning-enabled clinical decision aid, has been developed to manage backlogs in elective surgeries. It aims to optimise the use of high volume, low complexity surgical pathways by accurately stratifying patient risk, thereby facilitating the allocation of patients to the most suitable surgical sites. The tool augments elective surgical pathways by providing automated secondary opinions for perioperative risk assessments, enhancing decision-making. Its primary application is in elective sites utilising lighter pre-assessment methods, identifying patients with minimal complication risks and those high-risk individuals who may benefit from early pre-assessment.

The Phase 1 clinical evaluation of OpenPredictor entailed a prospective analysis of 156 patient records from elective hip and knee joint replacement surgeries. Using a polynomial logistic regression model, patients were categorised into high, moderate, and low-risk groups. This categorisation incorporated data from various sources, including patient demographics, co-morbidities, blood tests, and overall health status.

In identifying patients at risk of postoperative complications, OpenPredictor demonstrated parity with consultant-led preoperative assessments. It accurately flagged 70% of patients who later experienced complications as moderate or high risk. The tool's efficiency in risk prediction was evidenced by its balanced accuracy (75.6%), sensitivity (70% with a 95% confidence interval of 62.05% to 76.91%), and a high negative predictive value (96.7%).

OpenPredictor presents a scalable and consistent solution for managing elective surgery pathways, comparable in performance to secondary consultant opinions. Its integration into pre-assessment workflows assists in efficient patient categorisation, reduces late surgery cancellations, and optimises resource allocation. The Phase 1 evaluation of OpenPredictor underscores its potential for broader clinical application and highlights the need for ongoing data refinement and system integration to enhance its performance.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 9 - 9
2 May 2024
Green J Holleyman R Kumar S Khanduja V Malviya A
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This study used a national registry to assess the outcomes of hip arthroscopy (HA) for the treatment femoroacetabular impingement (FAI).

All HAs for FAI recorded in the UK Non-Arthroplasty Hip Registry (NAHR) between January 2012 and September 2023 were identified. Cases were grouped according to the index procedure performed for FAI (cam, pincer, or mixed). Patient outcomes captured included the International Hip Outcome Tool (iHOT)-12.

7,511 HAs were identified; 4,583 cam (61%), 675 pincer (9%), 2,253 mixed (30%). Mean age (34.8) was similar between groups. There was a greater proportion of females in the pincer group (75%) compared to cam (52%) and mixed (50%). A higher proportion of patients had a recorded cartilage injury in association with a cam lesion compared to pincer. The pincer group had poorer mean pre-op iHOT-12 scores (31.6 \[95%CI 29.9 to 33.3\]; n=364) compared to cam (33.7 \[95%CI 32.1 to 34.4\]; n=3,941) and achieved significantly lower scores at 12 months (pincer = 52.6 (50.2 to 55); n=249, cam = 58.3 (57.1 to 59.5); n=1,679).

Overall, significant (p < 0.0001) iHOT-12 and EQ-5D improvement vs baseline pre-operative scores were achieved for all FAI subtypes at 6 months (overall mean iHOT-12 improvement +26.0 \[95%CI 25.0 to 26.9\]; n=2,983) and maintained out to 12 months (+26.2 \[25.1 to 27.2\]; n=2,760) at which point 67% and 48% of patients continued to demonstrate a score improvement greater than or equal to the minimum clinically important difference (>/=13 points) and substantial clinical benefit (>/=28 points) for iHOT-12 respectively.

This study demonstrates excellent early functional outcomes following HA undertaken for FAI in a large national registry.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 63 - 63
2 May 2024
Green J Khanduja V Malviya A
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There is little known about how patient socioeconomic status impacts clinical outcomes in hip preservation surgery. The aim of this study was to evaluate the relationship between indices of multiple deprivation, funding provider (NHS Funded or Private Funded) and clinical outcomes following surgery for femoroacetabular impingement (FAI)

The study analysed the data of 5590 patients recorded in the NAHR who underwent primary hip arthroscopic treatment for FAI between November 2013 and July 2023. Records were matched to the UK National index of multiple deprivation using the lower layer super output area. Using iHOT12 score, patient reported outcome measures were analysed at base line and 1 year following surgery.

2358 records were matched to LLSOA deciles. Between the lowest (most deprived) 3 deciles and the highest (least deprived) the average baseline iHOT12 score was 28.98 (n=366) and 35.33 (n=821). The proportion of patients receiving treatment through NHS funding compared to independent funding for the most deprived, 292 (90%) 37 (10%) respectively compared to the least deprived 515 (70%) and 244 (30%) respectively. At 1year, iHOT12 scores for each group were 51.64 (29.1 SD) compared to 61.5 (28.06 SD) respectively.

The study demonstrates that patients from lower socioeconomic backgrounds had poorer baseline and one-year post-surgery iHOT12 scores compared to those from higher socioeconomic strata. Furthermore, a higher reliance on NHS funding was observed among the most deprived, while more affluent patients predominantly opted for private funding. These findings underscore the significant influence of socioeconomic status on both the quality of healthcare received and recovery outcomes in hip preservation surgery, calling attention to the need for more equitable healthcare solutions.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 49 - 49
2 May 2024
Green J Khanduja V Malviya A
Full Access

Femoroacetabular Impingement (FAI) syndrome, characterised by abnormal hip contact causing symptoms and osteoarthritis, is measured using the International Hip Outcome Tool (iHOT). This study uses machine learning to predict patient outcomes post-treatment for FAI, focusing on achieving a minimally clinically important difference (MCID) at 52 weeks.

A retrospective analysis of 6133 patients from the NAHR who underwent hip arthroscopic treatment for FAI between November 2013 and March 2022 was conducted. MCID was defined as half a standard deviation (13.61) from the mean change in iHOT score at 12 months. SKLearn Maximum Absolute Scaler and Logistic Regression were applied to predict achieving MCID, using baseline and 6-month follow-up data. The model's performance was evaluated by accuracy, area under the curve, and recall, using pre-operative and up to 6-month postoperative variables.

A total of 23.1% (1422) of patients completed both baseline and 1-year follow-up iHOT surveys. The best results were obtained using both pre and postoperative variables. The machine learning model achieved 88.1% balanced accuracy, 89.6% recall, and 92.3% AUC. Sensitivity was 83.7% and specificity 93.5%. Key variables determining outcomes included MCID achievement at 6 months, baseline iHOT score, 6-month iHOT scores for pain, and difficulty in walking or using stairs.

The study confirmed the utility of machine learning in predicting long-term outcomes following arthroscopic treatment for FAI. MCID, based on the iHOT 12 tools, indicates meaningful clinical changes. Machine learning demonstrated high accuracy and recall in distinguishing between patients achieving MCID and those who did not. This approach could help early identification of patients at risk of not meeting the MCID threshold one year after treatment.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_9 | Pages 41 - 41
1 May 2017
Staunton P Baker J Green J Devitt A
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Background The internet is an increasingly utilised resource for accessing information regarding a variety of heath conditions. YouTube is a popular video sharing platform used to both seek and distribute information online.

Materials & Methods

A search for ‘scoliosis’ was carried out using YouTube's search engine and data was collected on the first fifty videos returned. A JAMA score (to determine currency, authorship, source and disclosure) and scoliosis specific score (that measures the amount of information on the diagnosis and treatment options as devised by Mathur et al in 2005; scored 0–32) was recorded for each video to measure quality objectively. Additionally the number of views, number of comments and feedback positivity was documented for each. Data analysis was conducted using R 3.1.4/R Studio 0.98 with control for the age of each video in analysis models.

Results

The average number of views per video was 71,152 with an average length of 7 minutes 32 seconds. Thirty six percent of the videos fell under the authorship category of personal experience. The average JAMA score was 1.32/4 and average scoliosis specific score was 5.38/32. There was a positive correlation between JAMA score and number of views P=0.003. However in contrast there was a negative correlation between scoliosis specific score and number of views P=0.01.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 159 - 159
1 Sep 2012
Baker J Green J Synnott K Stephens M Poynton A Mulhall K
Full Access

Background

The internet has revolutionized the way we live our lives. Over 60% of people nationally now have access to the internet. Healthcare is not immune to this phenomenon. We aimed to assess level of access to the internet within our practice population and gauge the level of internet use by these patients and ascertain what characteristics define these individuals.

Method

A questionnaire based study. Patients attending a mixture of trauma and elective outpatient clinics in the public and private setting were invited to complete a self-designed questionnaire. Details collected included basic demographics, education level, number of clinic visits, history of surgery, previous clinic satisfaction, body area affected, whether or not they had internet access, health insurance and by what means had they researched their orthopedic complaint.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 418 - 418
1 Apr 2004
Kirking B Green J Parduhn C
Full Access

Numerous studies have reported on the effects of modular insert design on stress at the tibial/femoral articular surface. However, while the insert / tibial component surface (“backside”) wear and motion have been investigated, backside stress is not well delineated. Because stress may be related to observed backside damage, this study addressed the backside stress response to insert thickness, material, and articular geometry.

Twelve Natural Knee II tibial inserts (Sulzer Orthopedics Inc.) with three thicknesses (6, 12.5, and 18.5 mm), two materials (Durasul and 4150 UHMWPE), and two types of condylar geometry (congruent and ultra-congruent) were tested. Fuji film was placed between the baseplate and insert. A femoral component was loaded onto the insert in axial compression at four times Body Weight. The film was scanned into Adobe Photoshop to measure mean and peak luminosity, which was converted into stress. Analysis of Variance was performed with main effects and all two-way interactions to determine significance.

The mean stress ranged from 0.61 to 3.92 MPa and the peak stress ranged from 2.17 to 10.4 MPa. Insert thickness significantly influenced both mean (p=0.001) and peak (p=0.001) backside stress. Stress for the 6 mm inserts (7.17 MPa mean, 9.91 MPa peak) were approximately 2.1 times the 12.5 mm inserts (3.47 MPa mean, 4.66 MPa peak), and were approximately 2.6 times the 18.5 mm inserts (2.74 MPa mean, 3.71 MPa peak). There was not a significant effect on mean or peak stress from material or condylar geometry. None of the interactions were significant.

This study provides two important contributions. First, it establishes the backside stress magnitude during simple loading. Second, the relationship between backside stress and the insert thickness is experimentally quantified. Understanding this stress magnitude and response may be important to controlling observed in-vivo backside damage.


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 1 | Pages 159 - 160
1 Jan 1995
David H Green J Grant A Wilson C


The Journal of Bone & Joint Surgery British Volume
Vol. 62-B, Issue 3 | Pages 337 - 339
1 Aug 1980
Chapman J Deakin D Green J

Eight slipped upper femoral epiphyses in patients who had had radiotherapy are described. These cases involved five patients in an "at risk" population of 48. This increased incidence is highly significant.