Revision surgery and debridement and implant retention are recognised approaches for managing prosthetic joint infections (PJI) but may not always be indicated. If the patient is unable to have or declines surgery, prolonged suppressive antibiotic therapy (PSAT) is an option. This study aims to define outcomes of PSAT from a single unit. A retrospective study was performed. All cases of PJI involving the hip or knee between 2012 and 2017 were identified from our institutional database and cross referenced with patient notes. One hundred and seventy eight cases were identified. Of these, 23 (12.9%) (10 hips, 13 knees) were treated with PSAT. Infection was diagnosed based on the MSIS criteria in all cases and all cases were managed by a multidisciplinary team which included specialist microbiologists. One case of long term antifungal therapy was additionally identified. Co-morbidity was assessed using the Charlson co-morbidity index. Exacerbations of infection and need for further surgery were recorded.Aim
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