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The Bone & Joint Journal
Vol. 101-B, Issue 7_Supple_C | Pages 22 - 27
1 Jul 2019
Kalbian IL Tan TL Rondon AJ Bonaddio VA Klement MR Foltz C Lonner JH

Aims

Unicompartmental knee arthroplasty (UKA) provides improved early functional outcomes and less postoperative morbidity and pain compared with total knee arthroplasty (TKA). Opioid prescribing has increased in the last two decades, and recently states in the USA have developed online Prescription Drug Monitoring Programs to prevent overprescribing of controlled substances. This study evaluates differences in opioid requirements between patients undergoing TKA and UKA.

Patients and Methods

We retrospectively reviewed 676 consecutive TKAs and 241 UKAs. Opioid prescriptions in morphine milligram equivalents (MMEs), sedatives, benzodiazepines, and stimulants were collected from State Controlled Substance Monitoring websites six months before and nine months after the initial procedures. Bivariate and multivariate analysis were performed for patients who had a second prescription and continued use.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 69 - 69
1 Apr 2019
Blevins K Danoff J Goel R Foltz C Chen AF Hozack W
Full Access

Introduction

The purpose of this study is to compare total and rate of caloric energy expenditure between conventional and robotic-arm assisted total knee arthroplasty (TKA) between a high volume “veteran” surgeon (HV) and a lower volume, less experienced surgeon (LV).

Methods

Two specialized arthroplasty surgeons wore a biometric-enabled shirt and energy expenditure outcomes were measured (total caloric expenditure, kilocalories per minute, heart rate variability, and surgical duration) during 35 conventional (CTKA) and 29 robotic primary total knee arthroplasty (RTKA) procedures.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 7 - 7
1 Oct 2018
Bell K Foltz C Makhdom A Star AM Arnold WV Hozack WJ Craft DV Austin MS
Full Access

Introduction

Opioid abuse is a national epidemic. Traditional pain management after total knee arthroplasty (TKA) relied heavily on opioids. The evidence that in-hospital multimodal pain management (MMPM) is more effective than opioid-only analgesia is overwhelming. There has been little focus on post-discharge pain management. The purpose of this study was to determine whether MMPM after TKA could reduce opioid consumption in the 30-day period after hospital discharge.

Methods

This was a prospective, two-arm, comparative study with a provider cross-over design. The first arm utilized a standard opioid-only (OO) prn regimen. The second arm utilized a 30-day MMPM regimen (standing doses of acetaminophen, metaxalone, meloxicam, gabapentin) and opioid medications prn. Surgeons crossed over protocols every four weeks. The primary outcome measure was VAS pain score. Secondary outcome measures included morphine milligram equivalents (MME) consumed, failure of the protocol, and manipulation under anesthesia (MUA). A pre-hoc power analysis was performed for the primary outcome measure and an intent-to-treat analysis was done utilizing a longitudinal mixed model.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 6 - 6
1 Oct 2018
Rondon AJ Tan TL Kalbian I Bonaddio V Klement MR Foltz C Lonner JH
Full Access

Introduction

The prescription of opioids has increased in the last two decades. Recently, several states have developed online Prescription Drug Monitoring Programs aimed at preventing overprescribing of controlled substances. Unicompartmental knee arthroplasty (UKA) has been shown to provide improved early functional outcomes, faster recovery, and less postoperative morbidity and pain than total knee arthroplasty (TKA). The aim of this study is to evaluate differences in opioid prescription requirements between patients undergoing TKA and UKA.

Methods

We retrospectively reviewed consecutive series of primary TKA from January 2017 to July 2017 and primary UKA from January 2016 to July 2017 using standardized perioperative pain protocols. All patients that underwent any other procedure 6 months prior to and after index surgery were excluded, resulting in 740 TKA and 241 UKA. Demographic and comorbidity information was collected for all patients. Opioid prescriptions, morphine milligram equivalents (MME), sedatives, benzodiazepines, and stimulants were collected from State Controlled Substance Monitoring website 6 months prior and after index procedures. Univariate and multivariate analysis were performed for patients that had a second prescription and continued use (defined as more than 6 months postoperatively).


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_13 | Pages 60 - 60
1 Oct 2018
Fleischman AN Tarabichi M Makar G Foltz C Hozack WJ Austin MS Chen AF
Full Access

Background

Orthopedic surgeons have relied heavily on opiates after total hip replacement (THR) despite no clear evidence of benefit and a rapidly growing abuse epidemic. Multimodal analgesia may reduce or even obviate the need for opiates after elective surgery.

Methods

In a cluster-randomized, crossover trial, 235 patients undergoing THR were assigned to receive multimodal analgesia with minimal opiates (Group A-10 tablets), multimodal analgesia with a full opiate supply (Group B-60 tablets), or a traditional opiate regimen without multimodal analgesia (Group C-60 tablets). The multimodal regimen comprised scheduled-dose acetaminophen, meloxicam, and gabapentin. Primary outcomes were daily pain and opiate utilization for the first 30-days. Secondary outcomes included assessments of satisfaction, sleep-quality, opiate-related symptoms, hip function, and adverse events.


The Bone & Joint Journal
Vol. 100-B, Issue 8 | Pages 1125 - 1132
1 Aug 2018
Shohat N Foltz C Restrepo C Goswami K Tan T Parvizi J

Aims

The aim of this study was to examine the association between postoperative glycaemic variability and adverse outcomes following orthopaedic surgery.

Patients and Methods

This retrospective study analyzed data on 12 978 patients (1361 with two operations) who underwent orthopaedic surgery at a single institution between 2001 and 2017. Patients with a minimum of either two postoperative measurements of blood glucose levels per day, or more than three measurements overall, were included in the study. Glycaemic variability was assessed using a coefficient of variation (CV). The length of stay (LOS), in-hospital complications, and 90-day readmission and mortality rates were examined. Data were analyzed with linear and generalized linear mixed models for linear and binary outcomes, adjusting for various covariates.