Osteloysis following metal-on-UHMW polyethylene Total Hip Arthroplasty (THA) is well reported, as is lack of osteolysis following Ceramic-on-Ceramic (CoC)THA. Early ceramic failures did report some osteolysis, but in flawed implants. As 3rd and now 4th generation ceramic THAs come into mid- and long-term use, the orthopaedic community has begun to see reports of high survival rates and very low incidence of osteolysis in these bearings. Osteolysis reported after 3rd generation CoC THA often included metallosis due to neck rim impingement. In our department we have revised only 2 hips in over 6000 CoC THAs for osteolysis. Both had evidence of metallosis as well as ceramic wear. The technique used by Radiologists for identifying the nature of lesions on CT is the Hounsfield score which will identify the density of the tissue within the lucent area. It is common for radiologist to have no access to previous imaging, especially pre-operative imaging if a long time has elapsed. With such a low incidence of osteolysis in this patient group, what, then, should a surgeon do on receiving a CT report on a ceramic-on-ceramic THA which states there is osteolysis? Revision of such implants in elderly patients has a high risk of morbidity and mortality. This retrospective review aims to determine the accuracy of CT in identifying true osteolysis in a cohort of long-term third generation ceramic-on-ceramic uncemented hip arthroplasties in our department.Introduction
Objectives
The possibility of corrosion at the taper junction of hip replacements was initially identified as a concern of generating adverse reactions in the late 1980s. Common clinical findings of failure are pain, clicking, swelling, fluid collections, soft tissue masses, and gluteal muscle necrosis identified intra operatively. The joint replacement surgery was performed utilizing a posterior approach to the hip joint. The data from all surgical, clinical and radiological examinations was prospectively collected and stored in a database. Patients were separated into two groups based on bearing material, where group 1 had a CoC bearing and ABG modular stem whilst group 2 had a MoM bearing and SROM stem, with each group having 13 cases. Pre-operative revision surgery and post-operative blood serum metal ion levels we collected. Cup inclination and anteversion was measured using the Ein-Bild-Roentgen-Analyse (EBRA) software. A range of 2–5 tissue sections was examined per case. 2 independent observers that were blinded to the clinical patient findings scored all cases. The tissue grading for the H&E tissue sections were graded based on the presence of fibrin exudates, necrosis, inflammatory cells, metallic deposits, and corrosion products. The corrosion products were identified into 3 groups based on visible observation and graded based on abundance. A scanning electron microscope (SEM) Hitachi S3400 was used to allow for topographic and compositional surface imaging. Unstained tissue sections were used for imaging and elemental analysis. X-Ray diffraction was the analytical technique used for the taper debris that provided identification on the atomic and molecular structure of a crystal.Introduction
Methodology
Sagittal stability of the knee is believed to be of significant importance following total knee arthroplasty. We examine four different knee designs at a minimum of twenty-four months postoperatively. Sagittal stability was measured at four degrees of flexion: 0°; 30°; 60°; and 90°, to examine the effect of design on mid-flexion stability. The knee designs included were: the rotating platform LCS design (DePuy); the cruciate sparing Triathlon system (Stryker); SAIPH system (Matortho, UK); and the medial rotating knee design, MRK (Matortho, UK). Following ethical approval, 64 cases were enrolled into the study, 22 male and 42 female. Inclusion criteria included: a minimum of 18 months from surgery; ability to flex beyond 90 degrees; and have no postoperative complications. 18 LCS, 18 MRK, 14 SAIPH and 14 Triathlon knee designs were analysed. Sagittal stability was measured using the KT1000 device. Active range of movement was measured using a hand held goniometer and recorded as was Oxford knee score, WOMAC knee score, SF12 and Kujala patellofemoral knee score. Mean follow-up was 33.7 months postoperative, with a mean age of 72 years. Mean weight was 82.7kgs and height 164cms. There was no significant difference in preoperative demographics between the groups. Mean active post-operative range of motion of the knee was from 2–113° with no significant difference between groups. Sagittal stability was similar in all four groups in full extension; however the MRK and SAIPH designs showed improved stability in the mid-range of flexion (30–90°). Patient satisfaction also showed a similar trend with MRK achieving better patient reported functional outcomes and satisfaction than that of the SAIPH, LCS and Triathlon systems. All four knee designs demonstrated good post-operative range of movement with comparative improvement of patient scores to other reported studies. The MRK and SAIPH knee design showed an improved mid-flexion sagittal stability with better patient reported satisfaction and functional scores.
Total Hip Arthroplasty (THA) using the Direct Anterior Approach (DAA) is a muscle sparing approach which promotes early mobilisation of patients. It is a technically challenging approach shown to have a high rate of complications, especially during the learning curve. Here we present the results of 157 cases of THA via a DAA on a standard theatre table, with a minimum of 6 months follow-up. The authors conducted a prospective study on a group of 149 consecutive patients undergoing 157 cementless primary THAs for coxarthrosis, 8 bilateral. The same surgical technique was used in all patients, performed by the senior author WLW at a single centre. The average age of the patients at time of surgery was 69 years, 78% were female and 57% were right sided. All implants were uncemented, with bearings being ceramic on ceramic or Ceramic on highly cross-linked polyethylene. Patients were assessed clinically and radiographically pre- and post-operatively at 6 weeks, 6 months, 1 and 2 years. Intra-operatively, navigation was used to guide cup position and assess offset and leg length.Background
Materials & Methods
The 21st Century has seen ceramic bearings become an increasingly popular choice in total hip arthroplasty due to their high wear resistance and inert wear debris without osteolysis promising a long term bearing solution. Early ceramic bearings were hindered by fracture but improved manufacturing processes and materials subsequently produced stronger ceramics. These third generation ceramics showed greatly reduced fracture rates but there is limited evidence in the literature reporting their long term survival and wear characteristics. The purpose of this study was to determine osteolysis and survival rates of Alumina ceramic bearings in cementless total hip arthroplasties with a minimum follow-up of 15 years. We analyzed a series of 301 third-generation alumina-on-alumina cementless primary total hip replacements in 283 patients. The average age of the patients at the time of the arthroplasty was fifty-eight years, 51% were in women and 54% were right sided. All procedures were performed using the same surgical technique and the same implant at a single centre. Patients were followed up at six weeks, one, two, five, ten and 15 years. At 15 years postoperatively 46 patients (17%) had died of unrelated causes and 31 (10.2%) were lost to follow-up. Patients were assessed clinically and radiographically. Retrieved bearings were analyzed for wear.Introduction and Aims
Methods
The aim of this study is to describe the influence of sitting and standing posture on sagittal pelvic inclination in preoperative total hip replacement patients to assist with correct acetabular component positioning. Lateral radiographs of the pelvis and lumbar spine in sitting and standing of preoperative hip arthroplasty patients with primary hip osteoarthritis were extracted. Pelvic tilt was measured using the vertical inclination of a line from the ASIS to pubic tubercle. Sacral inclination was measured as the angle between the anterior surface of the sacrum and a horizontal reference. Figure one is a representation of the pelvic tilt angle and sacrel inclination angle taken during standing. The Cobb angle of the lumbar spine was recorded represented for a sitting patient in figure 2. Hip flexion was recorded (figure 2).Purpose
Methods
The accuracy of cup position in total hip arthroplasty is essential for a satisfactory result as malpositioning increases the risk of complications including dislocation, high wear rate, loosening, squeaking, edge loading, impingement and ultimately failure. We studied 173 patients in a single surgeon series of matched cohorts of patients who underwent total hip arthroplasty. Four separate groups were identified comprising of posterior approach +/− navigation and direct anterior approach +/− navigation. We found a significant difference between the direct anterior navigated group and the posterior non-navigated group for both anteversion (p < 0.05, CI −3.86 to −1.73) and inclination (p < 0.05, CI −3.08 to −1.08). 72% of anterior navigated patients fell within 5° of the navigation software set target cup position of 45° inclination and 20° anteversion and 100% were within 10°. Only 30% of posterior non-navigated were within 5° of both anteversion and inclination and 73% were within 10°. There was also a significant difference between the direct anterior navigated and non-navigated group with respect to anteversion only (p < 0.05, CI 1.50 to 1.30). There were no other significant differences between approaches +/− navigation. The direct anterior approach allows ease of access to both anterior-superior iliac spines for navigation and a supine patient allows anteversion and inclination to be measured in the frontal plane. We conclude that the direct anterior approach with navigation improves accuracy of cup position compared to the conventional posterior approach without navigation.
Squeaking is a potential problem of all hard on hard bearings yet it has been less frequently reported in metal-on-metal hips. We compared a cohort of 11 squeaking metal-on-metal hip resurfacings to individually matched controls, assessing cup inclination and anteversion between the groups to look for any differences. We retrospectively reviewed the patient records of 332 patients (387 hip resurfacings) who underwent hip resurfacing between December 1999 and Dec 2012. 11 hips in 11 patients were reported to squeak postoperatively. Each of these patients, except one, were matched by age, sex, BMI and implant to 3 controls. The final patient only had one control due to his high BMI. The latest post-operative radiographs of the squeaking group and controls were analysed using EBRA (Einzel-Bild-Roentgen-Analysis, University of Innsbruck, Austria) software to evaluate cup inclination and anteversion.Introduction
Methods
The design of the femoral prosthesis in cementless total hip arthroplasty is known to affect the initial strains in the cortex during implantation and in the early postoperative time period. High strains have a direct influence on periprosthetic fracture. This study compares the existing ABGII stem, which is proximally coated with a grit blasted titanium surface with hydroxyapatite coating with a prototype that has a rougher titanium plasma spray proximal coating. The Australian National Joint registry results 2011 reported the ABG2 femoral component cumulative percent revision (CPR) of 6.5 (93.5% survival), which compares favourably with equivalent stems with 10 year CPR data such as the Taperloc 6.6 and Corail 7.3. Six pairs of fresh-frozen cadaveric femurs were mounted in blocks according to ISO guidelines in single leg stance setup. Five strain gauges were attached around the neck of the femur and then prepared according to routine operative techniques to accept the femoral prosthesis. Cortical strains were measured during insertion of the prosthesis with an instrumented mallet attached to an accelerometer. Subsequently, force-displacement readings were taken during cyclical loading on a servo-hydraulic machine and finally the stems were tested to failure. Our results showed significantly less strain during cyclical loading of the stem with increased surface roughness (p < 0.05). They also showed no significant differences loads/strains during impaction (p = 0.159), no significant difference in micromotion (p = 0.148) and no significant difference in load-to-failure (p = 0.37).
The success of total hip arthroplasty has meant its indications have been extended to the younger more active patient. Due to the higher activity levels and increased demands of these patients, revision rates have been traditionally higher than when compared to older patients [1]. Ceramic on ceramic bearings may offer a viable long term solution as manufacturing methods have evolved resulting in improved mechanical properties, particularly of third and fourth generation ceramics. We report the outcome of primary cementless, alumina-on-alumina hip arthroplasty with a minimum 10 year follow up in 110 patients under the age of 55 years of age at time of surgery. A series of 120 consecutive total hip arthroplasties in 110 patients were performed between June 1997 and February 1999 by the two senior authors. All patients had an Osteonics ABC acetabular component and SecurFit or SecurFit Plus femoral component (Stryker Orthopaedics, Mahwah, NJ) with an alumina C-taper ceramic head (Biolox Forte, Ceramtec, Plochingen, Germany).Introduction
Methods
Sagittal stability of the knee is believed to be of significant importance following a total knee arthroplasty. We examine three different knee designs at a minimum of twenty-four months postoperatively. Sagittal stability was measured at four degrees of flexion; 0°, 30°, 60° and 90° to examine the effect of design on mid-flexion stability. The knee designs included the rotating platform LCS design, the cruciate sparing Triathlon system and the medial rotating knee design, MRK. Following ethical approval 50 cases were enrolled into the study, 15 male and 35 female. Eighteen LCS, 18 MRK and 14 Triathlon knee designs were analysed. Sagittal stability was measured using the KT1000 device. Active range of movement was measured using a hand held goniometer and recorded as was Oxford knee score, WOMAC knee score, SF12 and Kujala patellofemoral knee score. Mean follow-up was 37 months postoperative with a mean age of 73 years. Mean weight was 82.7 kgs and height 164 cms. There was no significant difference in preoperative demographics between the groups. Mean active post-operative range of motion of the knee was from 2–113° with no significant difference between groups. Sagittal stability was similar in all three groups in full extension; however the MRK design showed improved stability in the mid-range of flexion (30–90°). Patient satisfaction also showed a similar trend with MRK achieving slightly better patient reported outcomes than that of the LCS and Triathlon systems, although this was not statistically significant. All three knee designs demonstrated good post-operative range of movement with comparative improvement of patient scores to other reported studies. The MRK knee design showed an improved mid-flexion sagittal stability.
The purpose of this study was to prospectively measure serum cobalt and chromium ion levels in patients who had MITCH Resurfacing (Stryker) and to correlate these with acetabular component orientation (anteversion and inclination). Twenty-seven patients were enrolled in the study. Serum ion levels were measured pre-operatively, six weeks, six months, twelve months and twenty-four months post-operatively. Axial CT scans of the pelvis were used to measure cup anteversion and plain radiographs used to measure cup inclination. The median serum cobalt and chromium levels at one year were 14.5 nmol/l (range, 6 nmol/l to 59 nmol/l) and 36 nmol/l (range, 17nmol/l to 63 nmol/l) respectively. The median serum cobalt and chromium levels at two years were 16.5 nmol/l (range, 6 nmol/l to 75 nmol/l) and 37.5 nmol/l (range, 13 nmol/l to 109 nmol/l) respectively. The mean cup inclination was 43° (range, 30° to 60°). The mean cup anteversion was 19° (range, 1° to 47°). There was no clear correlation with cup position and serum ion levels. There was one outlier with slightly elevated chromium (109 nmol/l) in a female with a small head size. All patients at all time points showed serum cobalt and chromium levels below the level indicating a high-risk implant (7 parts per billion or chromium >134 nmol/l and cobalt > 119 nmol/l). Our results show no clear relationship between cup position and serum metal ions in this group of patients with relatively well-positioned components
Edge loading commonly occurs in all bearings in hip arthroplasty. The aim of this study compares metal bearings with edge loading to alumina bearings with edge loading and to metal bearings without edge loading. Seventeen failed large diameter metal-on-metal hip bearings (8 total hips, 9 resurfacings) were compared to 55 failed alumina-on-alumina bearings collected from 1998 to 2010. The surface topography of the femoral heads was measured using a chromatically encoded confocal measurement machine (Artificial Hip Profiler, RedLux Ltd.). The median time to revision for the metal hip bearings and the alumina hip bearings was 2.7 years. Forty-six out of 55 (84%) alumina bearings and 9 out 17 (53%) metal bearings had edge loading wear (p<0.01). The average volumetric wear rate for metal femoral heads was 7.87 mm3/yr (median 0.25 mm3/yr) and for alumina heads was 0.78 mm3/yr (median 0.18 mm3/yr) (p=0.02). The average volumetric wear rate for metal heads with edge loading was 16.51 mm3/yr (median 1.77 mm3/yr) and for metal heads without edge loading was 0.19 mm3/yr (median 0 mm3/yr) (p=0.1). There was a significant difference in gender, with a higher ratio of females in the alumina group than the metal group (p=0.02). Large diameter metal femoral heads with edge loading have a higher wear rate than smaller alumina heads with edge loading. Metal-on-metal bearings have low wear when edge loading does not occur.
Alumina ceramic on ceramic bearings in total hip arthroplasty (THA) may reduce the prevalence of osteolysis due to its properties of low wear and chemical inertness. This is critical in the younger patient population as they place increased demands over a longer period. This study reports on the clinical and radiographic outcomes of a series of modern cementless ceramic on ceramic THA at a minimum of 10 years in this younger group. A series of 120 consecutive third generation ceramic cementless THA were performed at a single centre in 110 patients from 1997 to 1999. The average age of the patients at the time of surgery was 45 years (20 to 55 years). All procedures were carried out via the posterior approach using the same implant by the two senior authors.Aim
Method
Two types of ceramic materials currently used in total hip replacements are third generation hot isostatic pressed (HIPed) alumina ceramic (commercially known as BIOLOX®forte, CeramTec) and an alumina matrix composite material consisting of 75% alumina, 24% zirconia, and 1% mixed oxides (BIOLOX®delta, CeramTec). The aim of this study is to compare BIOLOX delta femoral heads to BIOLOX forte femoral heads revised within 2 years in vivo. Ceramic bearings revised at one center from 1998 to 2010 were collected (61 bearings). BIOLOX delta heads (n=11) revised between 1–33 months were compared to BIOLOX forte femoral heads with less than 24 months in vivo (n=20). The surface topography of the femoral heads was measured using a chromatically encoded confocal measurement machine (Artificial Hip Profiler, RedLux Ltd.). The median time to revision for BIOLOX delta femoral heads was 12 months, compared to 13 months for BIOLOX forte femoral heads. Sixteen out of 20 BIOLOX forte femoral heads and 6 out of 11 BIOLOX delta femoral heads had edge loading wear. The average volumetric wear rate for BIOLOX forte was 0.96 mm3/yr (median 0.13 mm3/yr), and 0.06 mm3/yr (median 0.01 mm3/yr) for BIOLOX delta (p=0.03). There was no significant difference (p>0.05) in age, gender, time to revision or femoral head diameter between the two groups. Early results suggest less volumetric wear with BIOLOX delta femoral heads in comparison to BIOLOX forte femoral heads.
Pseudotumours have been associated with metal-on-metal (MoM) hip replacements. We define it as a solid mass which may have cystic components that is neither neoplastic nor infectious in aetiology. The cause of a pseudotumour is not fully understood but could be due to excessive wear, metal hypersensitivity or due to an as-yet unknown cause. We present the retrieval analysis of early failure MoM hips revised for pain, loosening or a symptomatic mass. Tissues and implants were examined for the possible causes of failure and pseudotumour formation. Corrosion as a potential new cause for pseudotumour formation will be presented.Background
Aim
Squeaking ceramics bearing surfaces have been recently recognised as a problem in total hip arthroplasty. The position of the acetabular cup has been alluded to as a potential cause of the squeaking, along with particular combinations of primary stems and acetabular cups. This study has used the finite element method to investigate the propensity of a new large diameter preassembled ceramic acetabular cup to squeaking due to malpositioning. A verified three-dimensional FE model of a cadaveric human pelvis was developed which had been CT scanned, and the geometry reconstructed; this was to be used to determine the behaviour of large diameter acetabular cup system with a thin delta ceramic liner in the acetabulum. The model was generated using ABAQUS CAE pre-processing software. The bone model incorporated both the geometry and the materials properties of the bone throughout based on the CT scan. Finite element analysis and bone material assignment was performed using ABAQUS software and a FORTRAN user subroutine. The loading applied simulated edge loading for rising from a chair, heel-strike, toe off and stumbling. All results of the analysis were used to determine if the liner separated from the shell and if the liner was toggling out of the shell. The results were also examined to see if there was a propensity for the liner to demobilise and vibrate causing a squeaking sound under the prescribed loading regime. This study indicates that there is a reduction in contact area between the ceramic liner and titanium shell if a patient happens to trip or stumble. However, since the contact between the liner and the shell is not completely lost the propensity for it to squeak is highly unlikely.
Reasons for failure of hip resurfacing arthroplasty include femoral neck fracture, loosening, femoral head osteonecrosis, metal sensitivity or toxicity and component malpositioning. Patient factors that influence the outcome include prior surgery, body mass index, age and gender, with female patients having two and a half times greater risk of revision by 5 years than males We explore the relationship between component size and the factors that may influence the survivorship of this procedure, resulting in higher revision rates with smaller components. These include femoral neck loading, edge loading, wear debris production and the effects of metal ions, cement penetration, component orientation, and femoral head vascularity. In particular the way the components are scaled from the large sizes down to the smaller sizes results in some marked changes in interactions between the implant and the patient. Wall thickness of the acetabular and femoral component does not change between the large and small sizes in most devices. This results in a relative excessively thick component in the small sizes. This may cause more acetabular and femoral bone loss, increased risk of femoral neck notching and relative undersizing of the component where acetabular bone is a limiting factor. Stem thickness does not change throughout the size range in many of the devices leading to relatively more femoral bone loss and a greater stiffness mismatch between the femoral stem and the bone. Relatively stiffness between the femoral stem and the bone is up to six times greater in the small size compared to the large size in some designs. The angle subtended by the articular surface (the articular arc) ranges from 170° down to as low as 144° in the small sizes of some devices. A smaller articular arc increases the risk of edge loading, especially if there is any acetabular component malpositioning. Acetabular inclination has been related to metal ion levels 5 and to the early development of pseudotumour An acetabular component with a radiographic inclination of 45° will have an effective inclination anywhere from 50° to 64° depending on the type and size of the component. This corresponds to a centre-edge angle from 40° down to 26°. The effective anteversion is similarly influenced by design. The result of a smaller articular arc is to reduce the size of the ‘safe window’ which is the target for orthopaedic surgeons.
