header advert
Results 21 - 29 of 29
Results per page:
Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 416 - 416
1 Jul 2010
Bottomley N McNally E Ostlere S Beard D Gill H Kendrick B Jackson W Gulati A Simpson D Murray D Dodd C Price A
Full Access

Introduction: This study explores whether modern magnetic resonance imaging (MRI) with improved cartilage sequencing is able to show a more detailed view of anteromedial osteoarthritis of the knee (AMOA). Preoperative assessment of patients and selection of intervention is very important and preoperative imaging forms an integral part of this. Modern MRI technology may allow us to visualize in great detail the structures and cartilage within the knee, providing a better understanding of the pathoanatomy of AMOA. This will be useful in preoperative assessment and surgical management of patients.

Methods: 50 patients with a radiographic diagnosis of anteromedial osteoarthritis of the knee and had been listed for unicompartmental knee arthroplasty (UKA) had MRI as part of their pre-op workup. At operation all were deemed suitable for UKA using the current Oxford indications. The image sequences were coronal, axial and sagittal with a predetermined cartilage protocol. The state of the ACL, cartilage wear location and pattern, presence of osteophytes and subchondral high signal were assessed.

Results: All the ACLs were visualized and in continuity, however 40% showed intrasubstance high signal.

100% of medial compartments showed full thickness anteromedial loss with preservation of the posteromedial cartilage. When present, the meniscus was extruded in 96% of cases.

90% of lateral compartments were normal and none had full thickness cartilage loss. However 10% showed high signal in the tibial plateau.

There was a highly reproducible pattern of osteophyte formation; 94% posteromedial and posterolateral aspect of medial femoral condyle; 90% medial tibial; 80% medial femoral and 84% lateral intercondylar notch.

Discussion: This study maps the pattern of anteromedial osteoarthritis using modern MRI techniques. This has importance in determining preoperative indications (preservation of ACL and posteromedial cartilage); surgical technique (determine pattern of osteophytes requiring resection) and potentially important for long-term outcome (early lateral compartment changes).


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 414 - 414
1 Sep 2009
Simpson D Pandit H Gulati A Gray H Beard D Price A Murray D Gill H
Full Access

Statement of purpose: The aim of this study is to evaluate different designs of unicompartmental knee replacement (UKR) by comparing the peak von Mises and contact stresses in polyethylene (PE) bearings over a step-up activity.

Summary of Methods: A validated finite element (FE) model was used in this study. Three UKR designs were modelled: a spherical femoral component with a spherical PE bearing (fully-congruent), a poly-radial femoral component with a concave PE bearing (semi-congruent), and a spherical femoral component with a flat bearing (non-congruent).

Kinematic data from in-vivo fluoroscopy measurements during a step-up activity was used to determine the relative tibial-femoral position as a function of knee flexion angle for each model. Medial and lateral force distribution was adapted from loads measured in-vivo with an instrumented implant during a step-up activity. The affect that varying the bearing thickness has on the stresses in the bearing was investigated. In addition, varus-valgus mal-alignment was investigated by rotating the femoral component through 10 degrees.

Summary of Results: Only the fully congruent bearing experienced peak von Mises and contact stresses below the PE lower fatigue limit (17MPa) for the step-up activity (fully congruent PE peak contact stress, 5MPa). The highest PE contact stresses were observed for the semi-congruent and non-congruent designs, which experienced approximately 3 times the PE lower fatigue limit. Peak PE von Mises stresses for the semi-congruent and non-congruent designs were similar, peaking at approximately 25MPa. Peak PE von Mises stresses were ameliorated with increased bearing thickness. Varus-valgus mal-alignment had little effect on the peak stresses in the three UKR designs.

Statement of Conclusions: Fully congruent articulating surfaces significantly reduce the peak contact stresses and von Mises stresses in the bearing. The FE model demonstrates that fully congruent bearings as thin as 2.5mm can be used without increasing the contact stresses significantly. Fully congruent designs can use thinner bearings and enable greater bone preservation.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 414 - 414
1 Sep 2009
Simpson D Gray H Dodd C Beard D Price A Murray D Gill H
Full Access

Statement of purpose: Finite element (FE) models of bone can be used to evaluate new and modified knee replacements. Validation of FE models is seldom used, and the quantification of modelling parameters has a considerable effect on the results obtained. The aim of this study is to develop a FE model of a cadaveric tibia and validate it against a comprehensive set of experiments.

Summary of Methods: Seventeen tri-axial rosettes were attached to a cleaned, fresh frozen cadaveric human tibia and the tibia was subjected to 13 loading conditions. Deflection and strain data were used for comparison with the FE model. A geometric model was created on the basis of computed tomography (CT) scans. The CT data was used to map 600 orthotropic material properties to the tibia. All experiments were simulated on the FE model. Measured principal strains were compared to their corresponding FE values using regression analysis. The validated tibia model was reduced in size (75mm to the proximal) and then re-modelled to represent only the proximal tibia. This re-modelled tibia was validated against the reduced size FE model. Virtual surgery was performed on the validated proximal model to implant a UKR.

Summary of Results: For the whole tibia model, the regression line for all axial loads combined had a slope of 0.999, an intercept of −6.24 micro-strain, and an R2 value of 0.962. The root mean square error as a percentage was 5%. For the proximal tibia model, correlation coefficients of 0.989 and 0.976 were obtained for the maximum and minimum principal strains respectively.

Statement of Conclusions: An FE model of an implanted proximal tibia has been validated against experimental data. This model is able to accurately predict the deflection and stresses in a replaced knee joint to obtain clinically relevant information. This will provide a virtual model of unicompartmental arthroplasty, where variables such as fixation method and bearing mechanics can be assessed.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 1 | Pages 44 - 48
1 Jan 2006
Keene G Simpson D Kalairajah Y

Twenty patients underwent simultaneous bilateral medial unicompartmental knee arthroplasty. Pre-operative hip-knee-ankle alignment and valgus stress radiographs were used to plan the desired post-operative alignment of the limb in accordance with established principles for unicompartmental arthroplasty. In each patient the planned alignment was the same for both knees. Overall, the mean planned post-operative alignment was to 2.3° of varus (0° to 5°).

The side and starting order of surgery were randomised, using conventional instrumentation for one knee and computer-assisted surgery for the opposite side.

The mean variation between the pre-operative plan and the achieved correction in the navigated and the non-navigated limb was 0.9° (sd 1.1; 0° to 4°) and 2.8° (sd 1.4; 1° to 7°), respectively. Using the Wilcoxon signed rank test, we found the difference in variation statistically significant (p < 0.001).

Assessment of lower limb alignment in the non-navigated group revealed that 12 (60%) were within ± 2° of the pre-operative plan, compared to 17 (87%) of the navigated cases.

Computer-assisted surgery significantly improves the post-operative alignment of medial unicompartmental knee arthroplasty compared to conventional techniques in patients undergoing bilateral simultaneous arthroplasty. Improved alignment after arthroplasty is associated with better function and increased longevity.


The Journal of Bone & Joint Surgery British Volume
Vol. 87-B, Issue 11 | Pages 1480 - 1482
1 Nov 2005
Kalairajah Y Simpson D Cossey AJ Verrall GM Spriggins AJ

We carried out a prospective randomised study to evaluate the blood loss in 60 patients having a total knee arthroplasty and divided randomly into two equal groups, one having a computer-assisted procedure and the other a standard operation. The surgery was carried out by a single surgeon at one institution using a uniform approach. The only variable in the groups was the use of intramedullary femoral and tibial alignment jigs in the standard group and single tracker pins of the imageless navigation system in the tibia and femur in the navigated group.

The mean drainage of blood was 1351 ml (715 to 2890; 95% confidence interval (CI) 1183 to 1518) in the computer-aided group and 1747 ml (1100 to 3030; CI 1581 to 1912) in the conventional group. This difference was statistically significant (p = 0.001). The mean calculated loss of haemoglobin was 36 g/dl in the navigated group versus 53 g/dl in the conventional group; this was significant at p < 0.00001.

There was a highly significant reduction in blood drainage and the calculated Hb loss between the computer-assisted and the conventional techniques. This allows the ordering of less blood before the operation, reduces risks at transfusion and gives financial saving. Computer-assisted surgery may also be useful for patients in whom blood products are not acceptable.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 271 - 271
1 Nov 2002
Boyd K Simpson D
Full Access

Aim: To quantify the effect of overhead sports on static scapular position.

Method: Three cohorts of young adults were evaluated: Swimmers (n=35), Tennis players (n=32) and Controls (n=33). Scapular position was determined using the method described by DiVita. Details of overhead activities, hand dominance and history of shoulder injuries were obtained by questionnaire. All measurements were performed by a single observer.

Results: DiVita’s normalised ratios in dominant shoulders were 1.57±0.09 for swimmers, 1.61±0.11 for tennis players and 1.57±0.12 for controls. For non-dominant shoulders, the ratios were 1.58±0.1.5, 1.59±0.13 and 1.63±0.13 respectively. There were no significant differences between groups. Within male subjects, there were no differences in scapular size between athletes and controls on either dominant or non-dominant sides. However, scapular distance was significantly greater in swimmers in both shoulders (dominant p=0.009, non-dominant p=0.028) and in the dominant shoulder in tennis players (p=0.037) when compared with controls. Female athletes showed no differences in scapular size when compared with controls but female swimmers had greater scapular sizes on their non-dominant sides when compared with controls (p=0.016).

Conclusions: There were measurable anthropometric differences between athletes and controls that supported our hypothesis of greater scapular distances in both shoulders in swimmers and in the dominant shoulder in tennis players when compared with controls. However, these were not borne out using a normalised ratio. DiVita’s method of assessing static scapula position is readily applicable to clinical and sporting settings and proved reproducible with minimal equipment. It may be worthy of further investigation.


The Journal of Bone & Joint Surgery British Volume
Vol. 68-B, Issue 4 | Pages 654 - 655
1 Aug 1986
Simpson D


The Journal of Bone & Joint Surgery British Volume
Vol. 68-B, Issue 2 | Pages 301 - 304
1 Mar 1986
Simpson D Thomas N Aichroth P

We reviewed 230 patients an average of 34 months after they had undergone partial or total meniscectomy by surgeons of different experience in a busy unit. Open and arthroscopic meniscectomies were compared. Arthroscopic partial meniscectomy resulted in a significant reduction of inpatient stay and earlier return to work and sport. Analysis of the type of meniscal damage showed that arthroscopic removal of "bucket handles" achieved better results than open techniques. Comparatively poor results were found for lateral meniscectomy.


The Journal of Bone & Joint Surgery British Volume
Vol. 59-B, Issue 2 | Pages 143 - 151
1 May 1977
Fraser R Paterson D Simpson D

A retrospective survey has been made of forty children with spinal tumours. Difficulties in establishing the correct diagnosis are mentioned and the value of radiological and cerebrospinal fluid investigations discussed. The major orthopaedic disabilities are spinal deformity or instability, and paraplegia. The main factor in the development of the former is the site of laminectomy: the higher the level the greater is the likelihood of deformity or instability developing. Measures to prevent this distressing complication are discussed. The role of the orthopaedic surgeon in the management of these children is emphasised.