Introduction:

Endoprosthetic replacement of the proximal femur is common in the management of bone tumours and failed revision arthroplasty. This study seeks to compare those patients undergoing acetabular resurfacing at the time of femoral replacement with those patients where the native acetabulum was preserved.

Introduction:

Distal femoral replacement is recognised as the optimum treatment for malignant distal femoral tumours. Aseptic loosening is known to be a major cause for failure in these implants. Studies have indicated that the HA coated collar promotes osteointegration and bony in growth. This study compares long term aseptic loosening in implants with HA coated collars to those without in the immature skeleton.

Introduction:

Instability and synovitis of the lesser metatarsalphalangeal (MTP) joints is a significant cause of forefoot pain. Plantar plate imaging traditionally has been through MRI and fluoroscopic arthrography. We have described ultrasound arthrography as a less resource-intensive technique without radiation exposure. We report the correlation between ultrasound arthographic and surgical findings.

In patients with a tumour affecting the distal ulna it is difficult to preserve the function of the wrist following extensive local resection. We report the outcome of 12 patients (nine female, three male) who underwent excision of the distal ulna without local soft-tissue reconstruction. In six patients, an aggressive benign tumour was present and six had a malignant tumour. At a mean follow-up of 64 months (15 to 132) the mean Musculoskeletal Tumour score was 64% (40% to 93%) and the mean DASH score was 35 (10 to 80). The radiological appearances were satisfactory in most patients. Local recurrence occurred in one patient with benign disease and two with malignant disease. The functional outcome was thus satisfactory at a mean follow-up in excess of five years, with a relatively low rate of complications. The authors conclude that complex reconstructive soft-tissue procedures may not be needed in these patients.

Cite this article: Bone Joint J 2014;96-B:1392–5.

INTRODUCTION

Leg length discrepancy following total hip arthroplasty (THA) can be functionally disabling for affected patients and can lead on to litigation issues. Assessment of limb length discrepancy during THA using traditional methods has been shown to produce inconsistent results. The aim of our study was to compare the accuracy of navigated vs. non navigated techniques in limb length restoration in THA.

Statement of purpose

Circular frames treatment for limb reconstruction involves repeated follow up visits, and a substantial number of these appointments are for pin site review only, and incur a significant cost to the NHS. We advocate ‘Telemedicine’ as a logistically and economically viable option for routine post-operative review of pin-sites.

Background

Collagenase represents a novel non-surgical treatment for Dupuytrens disease. Xiapex (Injectable collagenase, Pfizer pharmaceuticals) was recently approved by the MHRA for clinical use. The main objective of this study was to assess the proportion of patients with Dupuytrens disease that are suitable for treatment with collagenase and the financial implications of its introduction.

Introduction

Renal homeostasis has been shown to influence mortality after hip fractures; this is true for patients with both chronic kidney disease, and those who develop acute renal dysfunction after surgery. We have examined the influence of impaired renal function upon mortality and length of stay. We investigated this relationship through accurate mathematical modelling of available biochemistry data on a cohort of hip fracture patients.

Purpose

We report our surgical management of a series of primary and metastatic tumours of the lumbosacral junction, highlighting different methods of fixation, outcome and complications.

Purpose

To report a retrospective study of 103 cases of primary spinal infection, the largest ever such series from the UK, analysing presenting symptoms, investigations, bacteriology and the results of treatment.

Introduction: Lesser metatarsophalangeal joint (MTPJ) instability is a common cause of forefoot pain. Instability is probably caused by tears of the plantar plate and collateral ligaments. We prospectively compared MRI and ultrasound with and without arthrography in the assessment of patients with MTPJ instability.

Materials and Methods: MTPJ instability was diagnosed by the draw test. Nineteen patients underwent imaging with consent. One musculoskeletal radiologist performed MRI arthrography and a different musculoskeletal radiologist performed ultrasonography supplemented with arthrography. Each radiologist reported his own study, blinded to the results of the other modality. Where possible, the radiological diagnosis was evaluated at surgery.

Results: MRI identified four full thickness plantar plate tears. In five studies no contrast was seen in the MTP joint and in 10 contrast was contained within the joint.

Ultrasound identified six full thickness plantar plate tears as hypoechoic zones that extended through the whole thickness of the plate. Eleven studies showed partial thickness tears. Two studies showed thinning of the plate. Ultrasound arthrography identified seven full thickness tears by extravasation of injected fluid into the flexor tendon sheath. Eleven studies showed partial thickness tears and one was normal. Ultrasound and ultrasound arthrography agreed in 14/19 patients. MRI agreed with ultrasound on 3 of 6 full thickness tears and with ultrasound arthrography in 4 of 6 full thickness tears. MRI gave additional information about the articular surfaces in four patients. Surgical comparison was available in 11/19 patients. Ultrasound with and without arthrography correctly predicted four partial thickness tears. Ultrasound arthrography correctly predicted 6/7 full thickness tears, MRI 3/7 and ultrasound 3/7.

Discussion: Ultrasound with arthrography appears the best modality to distinguish between partial and full-thickness tears. It is cheaper, simpler and can be performed in the outpatient setting. Larger studies with surgical confirmation are required to assess its value more precisely.

Introduction: Nonunion is a relatively common complication seen in orthopaedic practice. The treatment of nonunion has traditionally been revision fixation with autogenic bone grafting. Here we present our results of nonunion treatment using Osteogenic Protein -1 (OP1) and allograft paste.

Material and Methods: Forty Eight Patients with resistant nonunion including atropic, hypertrophic and infected nonunion were treated with a composite of osteogenic protein-1 and allograft paste. The series consisted of 28 males and twenty females. Average age was 54 years. The average duration of preoperative symptoms was 26 months (range 4 to 52). 28 of 48 patients had an average of three prior failed surgical attempts at union (range 1 to 6). There were thirty seven atrophic, four hypertrophic and seven infected nonunions (bone transport docking site nonunion).18 patients in the series had previous autogenic cancellous bone grafting to the fracture site for attempted union. 39 patients had revision internal fixation with application of OP-1 and allograft paste to the nonunion site. Average healing time was 6.5 months (Range 3.5–19). Three patients in this series had OP-1 insertion twice, one patient simultaneously had autogenic cancellous bone grafting with OP-1.

Results: Average follow-up was 16 months (range 4 to 38). Functional and radiological outcome was excellent in 33 patients, good in five patients and fair in three. 3 cases were ongoing. Three patients went on to non-union requiring revision surgery and are under review. One patient died during follow-up.

Conclusion: Results in our series indicate OP-1 (BMP-7) implanted with Opteform allograft paste are as effective as autogenic cancellous bone grafting in treating resistant bone nonunions.

Introduction: The Taylor spatial frame (TSF) (Smith & Nephew) is a hexapod ring fixator that utilises the Ilizarov principles. The TSFs design is based on the Stewart-Gough platform, the use of which was originally described in mechanical engineering. Due to its unique design the TSF is extremely versatile in limb reconstruction surgery, allowing six degrees of freedom bone fragment manipulation with a high degree of precision that is aided by correction planning software.

Methods: Between October 2003 and December 2008 66 consecutive patients were treated using the TSF by a single consultant surgeon. Median patient age was 45 (range 20–69). The original pathology included 18 mal-unions, 13 acute fractures, 10 medial compartment osteoarthritis (OA) of the knee with varus deformity, 8 infected nonunions, 7 limb length discrepancies, 5 nonunions, 3 ankle OA, 3 post traumatic posterolateral corner of the knee instability, 1 multiple epiphyseal dysplasia, 1 lateral compartment OA of the knee with valgus deformity, 1 deformity secondary to Polio. There were 10 ankles, 19 knees (1 femur, 18 tibiae) and 37 tibiae.

Results: The procedures performed were 16 high tibial osteotomies, 2 frame assisted platings, 8 bone transports, 32 deformity corrections, 14 Ankle arthrodesis (9 primary, 5 revision after nonunion), 9 limb lengthening and 1 derotation. The median bone transport distance and lengthening achieved is reported.

The median time spent in the frame was 21 weeks (range 9–81), including 8 patients who required 2 frames to complete their treatment.

54 cases had a satisfactory outcome in terms of union and deformity correction using only the TSF, 5 cases were ongoing. Complications included 1 below knee amputation, 2 docking site nonunions requiring ORIF, 2 nonunions after ankle arthrodesis requiring T2 nails. 2 frames were removed due to compliance issues. 2 patients developed deformity requiring Tendo-achilles lengthening. There were 2 DVTs and 2 non-fatal PEs. 1 patient suffered a fracture at a femoral pin-site after TSF removal which was treated with external fixation. The median Otterburn grade of pin-site infection was 2 (range 0–4).

Conclusion: The Taylor spatial frame was used successfully in several different pathologies ranging from acute trauma to chronic deformity. The TSF provides the surgeon with a reliable treatment strategy that is both versatile and accurate.

Introduction: Abnormal hip morphology, seen with conditions such as slipped capital femoral epiphyses and femoral head necrosis, can lead to repetitive contact between the femoral neck and the acetabular rim. Impingement is a significant cause of hip pain in young adults and may be a mechanism for the development of early osteoarthritis. The senior surgeon has modified a technique to debride the pathology responsible for femoroacetabular impingement through a mini anterior approach, obviating the need to dislocate the hip. We describe this technique and present early clinical outcomes.

Method: Between Jan 2006 and June 2008, ‘notchplasty’ for the surgical treatment of femoroacetabular impingement was performed by the senior author (AHN) or directly under his supervision in 38 hips. There were 17 male patients and 21 female patients with an average age of 31 years. Patients have been followed according to a prospective protocol with Oxford and Iowa hip scores obtained pre-operatively, at 3 months and at 1 year.

Results: This study is still in progress. Twenty nine patients have had 3 month follow up and 13 of these have now been followed up to one year. Four patients are still less than 3 months post op. Data was unobtainable for 5 patients. 1 patient was excluded from the study.

The overall Oxford hip score improved significantly from a mean pre-operative value of 35 to a mean post operative value of 22.9 at 3 months (p< 0.001).

The mean score at 1 year increased slightly to 27.3 points but this remains lower than the pre operative average.

We report no cases of osteonecrosis. One patient has since been scheduled to undergo resurfacing arthroplasty.

Conclusions: The technique described is a new method for managing these patients whilst avoiding the pit-falls of current operative methods. The method avoids detaching the straight head of rectus, thereby tremendously improving postoperative mobilisation. However, the long term benefit of debridement of the head-neck junction for Cam-type femoroacetabular impingement remains to be seen.

Introduction: The treatment of isolated medial compartment osteoarthritis (OA) in the young or physically active patient is a challenging problem for the orthopaedic surgeon.

The rationale for high tibial osteotomy (HTO) in medial compartment OA with varus deformity is to correct varus malalignment and to redistribute load to the non-diseased lateral compartment of the knee. Here we present our early to mid-term clinical and radiological findings.

Methods: Between October 2005 and April 2007 9 patients underwent HTO and TSF application. Pre-operative OA grade was recorded using the Ahlbäck classification. Radiographs were used to calculate the pre and post operative measurements for the tibiofemoral angle, the mechanical axis deviation and the tibial slope. Correction planning was carried out using the Spatialframe software package. All operations were performed by a single experienced consultant orthopaedic surgeon specialising in Ilizarov and limb reconstruction surgery. Pre and post-operative Oxford knee scores were collected for each patient.

Results: Median follow-up was 19 months (range 15–35). Median age at operation was 49 years (range 37–59). On preoperative radiographic examination eight knees were Ahlbäck grade 1 and one knee was Ahlbäck grade 2. The median time spent in the frame was 18 weeks (range 12–37). The median total angle of correction according to correction program given was 14 degrees (range 10–22) and the median duration of correction was 18 days (range 14–36) with 6 patients requiring an additional correction program.

2 patients subsequently underwent matrix induced autologous chondrocyte implant (MACI) for osteochondral defects.

In the primary OA group we found an improvement in mean Oxford knee score after HTO from 28.3 to 37.8/48 post-operatively. 1 patient was non-compliant with the correction and required a total knee replacement (TKR) for continued pain at 36 weeks post frame removal. 1 patient required fibular osteotomy during their correction.

6 (67%) of the 9 patients had a documented pin site infection. The median Otterburn grade was 3 (range 0–4). There were no cases of chronic bone infection.

Conclusions: High tibial osteotomy performed with the Taylor spatial frame presents a viable treatment option in active patients with early medial compartment OA. With TKR as an end point the survival rate of HTO for treatment of OA was 88.9% at a median of 19 months follow-up. Our results also indicate successful use of the technique in combination with MACI.

Background: Numerous researchers have documented posterior comminution to confer an increased incidence of non-union and avascular necrosis after internal fixation of both displaced and undisplaced intracpasular hip fractures. This prospective study of 1247 patients questions this association and shows that comminution does not cause a statistically significant increase in these complications of fracture healing.

Methods: Twelve hundred and forty-seven patients with 1247 intracapsular hip fractures (568 undisplaced and 679 displaced fractures) were treated with open reduction and internal fixation. All these had preoperative radiographs, which were evaluated for posterior comminution. All of them were followed up post-operatively for clinical and radiographic evidence of non-union and avascular necrosis. The incidence of complications in comminuted versus non-comminuted fractures was calculated in both undisplaced and displaced groups. These rates were then compared for statistical significance (p value =0.05).

Results: The undisplaced cases (n=568) comprised 557 non-comminuted and 11 comminuted fractures. The complication rates were 10.9% and 18.2% respectively. The difference was not significant, with a p value of 0.38. Displaced fractures (n=679) consisted of 588 non-comminuted and 91 comminuted cases. In this group, complication rates were 33% and 35% respectively, with a p value of 0.82.

Conclusions: For the 1247 patients studied, there was no association between the observation of comminution of the fracture on the pre-operative x-rays and the later development of fracture healing complications.

A neck of femur fracture is known to be a high risk factor for the development of pressure sores with an associated morbidity, mortality and cost. We have attempted to identify risk factors in these patients for the development of pressure sores by analysing prospectively collected data of 4654 consecutive patients (1003 males/3473 females). 3.8% developed pressure sores in the sacral, buttock or heel areas.

Patients factors that increased the risk of pressure sores were increased age (82.1 years versus 76.6 years), lower mental test score (4.65 versus 5.76), diabetes mellitus (pressure sore incidence 10.4%), higher ASA score (3.0 versus 2.7) and lower admission haemoglobin concentration (120gms versus 124gms). Those patients with an extracapsular fracture were more likely to develop pressure sores compared to patients with an intracapsular fracture (4.5% versus 3.1%). Being male was not a risk factor.

While the time interval between fall and admission was not significant, the time interval between admission and surgery was found to be an extremely significant risk factor. A fall in blood pressure during surgery (5.6%) was found to increase risk. Patients who underwent a dynamic hip screw were more likely to develop pressure sores (incidence 4.7%). Patients with an intracapsular fracture treated with internal fixation were less likely to develop pressure sores in comparison to those fractures treated with a hemiarthroplasty or a sliding hip screw (2.0% versus 4.7 versus 4.4%). No relationship was seen related to length of surgery or type of anaesthesia. Our incidence of pressure sores is lower than previously reported (30%). Whilst determining factors that increase the risk of pressure sores may not be sufficiently reliable to be used for the individual patient, taking appropriate preventative measures can reduce the incidence, particularly with reference to (optimising the patient pre-operatively and) reducing delays to surgery.

Hip fractures are one of the leading causes of morbidity in the elderly population. A large reduction in morbidity can be achieved if these individuals can have definitive treatment rapidly. However, this is not always achievable to a multi factorial host of contributing factors. Therefore, to enable us to understand some aspect of why these delays, if any occur, the following study was undertaken.

The purpose of the study is to relate the place at which the patient fell, to the time of day for admission to casualty. This will enable us to ascertain whether there is a relationship between the location of injury and the time taken to admission into hospital; if there is such a correlation, then it will enable us to identify factors which will expedite an individuals attendance to hospital.

Designs: Retrospective analysis of prospectively collected data for 5273 consecutive admission to one centre with a confirmed proximal femoral fracture from January 1989 to November 2006.

Setting: Peterborough District Hospital

Results: Individuals who sustained an injury inside their own home living alone were more likely to suffer a delay in attendance to the hospital with a fracture (Median 8 hours), compared to individuals who live in there own home living with one or more individual (Median 3 hours) or those who fell indoors at other locations (Median 5 hours) or outside (Median 2 hours) were their falls were witnessed. Also it was noticed that patients living in there own homes fell during the early hours of the day, while patients who had a fall outside fell mainly during ‘working hours’ where as patients in hospital mainly had a fall during night time or mid day.

Conclusion: There is a quantifiable correlation demonstrated between place of injury and the delay in attendance to hospital.

Loss of blood is inevitable during knee replacement surgery, sometimes requiring transfusion. Allogenic blood leads to a risk of disease transmission and immunological reaction. There are various practices used. There is still a risk of bacterial transmission with stored blood and haemolytic transfusion reactions can still occur. Data was collected between 1998 and 2006. There was data on transfusion in 1532 patients undergoing primary knee replacements. There were 1375 unilateral TKRs and 157 bilateral TKRs. After reducing the bilateral cases to one record per patient, it was agreed to restrict the main analysis to 1532 patients. Data was collected prospectively at a pre-admission clinic 3 weeks prior to surgery. Haemoglobin was checked and body demographics including BMI were obtained. Each patient also had a knee score assessed. All patients received a LMWH pre-op until discharge. A tourniquet was used in each case and all patients had a medial para-patellar approach. No drains were used and operation details such as a lateral release were recorded. As per unit protocol, patients with a post-op haemoglobin less than 8.5g/dl were transfused as were symptomatic patients with haemoglobin between 8.5g/dl and 10g/dl. Each of the possible predictive factors was tested for significant association with transfusion using chi-squared or t-tests as appropriate. Multiple logistic regression was used to test for the independent predictive of factors after adjusting for one another. Results show that transfusion was more likely if the patient was older, female, short, light or thin. Among peri-operative factors, the chance of a transfusion was increased for bilateral patients, those with low knee scores and those with high ASA scores. Also patients undergoing a lateral release, those with low pre-op haemoglobin and those with a large post-op drop were more likely to be transfused. All the significant variables were entered into a forward stepwise multiple logistic regression. Transfusion was significantly more likely in those undergoing a bilateral procedure, with a low BMI, low pre-op haemoglobin and those with a large post-op drop (> 3g/dl). Allogenic transfusion is associated with immune-related reactions, from pyrexia to urticaria to haemolytic transfusion reactions, which can be life threatening. There is also the risk of viral pathogen transmission. Women were shown to be almost twice as likely to need transfusion. This has been shown in previous studies and is thought to be due to women having a lower weight and pre-op haemoglobin, both of which were shown to be significant independent factors in increasing the risk of transfusion. A pre-operative haemoglobin of less than 13g/dl, a BMI less than 25, and undergoing a bilateral procedure were shown to have an increased risk of transfusion. For patients falling into these categories, measures can be planned to try and reduce this risk.

Introduction: Extent of fibular resection dramatically alters limb function. Aim of our study was to evaluate the functional outcome following resections for 23 malignant tumors of fibula.

Methods: 23 biopsy proven malignant tumors of fibula were included in the study. There were 11 cases of Ewings sarcoma (PNET), 8 osteosarcomas, 2 malignant fibrous histiocytoma and 1 each of synovial sarcoma and chondrosarcoma. Following chemotherapy (wherever indicated) limb salvage surgery was done in all cases. There were 9 proximal, 6 middle and 9 cases of distal third of fibula. Type I resection was done in all proximal and 4 tumors of middle third fibula. Type II fibular resection with reconstruction of ankle joint was done in 10 cases. Reversal of contralateral fibula to reconstruct the ankle was done in 7 cases. Allograft was used in 3 patients.

Results: Average follow up was for 4.5 years (2 to 7 years). 17 patients (68%) were alive after 4 years of surgery. Local recurrence was seen in 3 cases and these were treated by above knee amputation. 3 patients died within 1 year of surgery. 82% of survivors had a good to excellent functional outcome according to the MSTS functional evaluation criteria and 65% were able to bear full weight and had unlimited activity. Recurrence was commonest in patients with PNET. All patients undergoing reversed fibular grafting showed good functional outcome.

Discussion and Conclusion: Results of limb salvage in malignant fibular lesions is infrequently reported. Site of fibular lesion is critical in salvage surgery and need for further reconstruction. Good results are obtained with reversed contralateral fibular reconstruction of the ankle.