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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 545 - 545
1 Oct 2010
Campton L Bucknill A Clifford J Patten S
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Detailed preoperative planning is essential for open reduction and internal fixation of acetabular fractures if a successful outcome is to be achieved. Decisions such as patient positioning, approach, reduction techniques and implant positioning are greatly influenced by fracture pattern and displacement. These fractures are frequently complex and a thorough understanding of their 3-Dimensional (3D) form is necessary for pre-operative decision making.

A combination of biplanar x-rays, 2 Dimensional CT scans (Axial, Sagittal and Coronal multi-plane reformats) and, more recently, 3D CT reconstructions are provided routinely.

However, the 3D reconstructions are provided to surgeons as static 2D pictures of the 3D model (up to 6 different views), rather than a true 3D representation.

In this study we used dynamic 3D models to provide additional information to surgeons. The 3D models were generated on a standard desktop or laptop computer and can be used in the operating theatre (Osirix Dicom viewing software). These true 3D reconstructions allow the surgeon to manipulate the model himself in real time so that the fracture can be viewed at any angle and overlying fragments removed to expose deeper structures.

3 experienced consultant pelvic trauma surgeons reviewed plain radiographs and 2D Pelvic CT scans from 20 acetabular fractures. They were asked to make a preoperative plan with regard to fracture classification and planned surgical approach(s). At separate, time-spaced, sittings they were provided with a 3D Static and 3D Dynamic CT reconstruction in addition. They were blinded to any previous plan and the patients’ details.

A comparison was then made with regard to surgical plan and the time taken to make that plan with or without access to dynamic 3D models. The additional information provided by dynamic 3D modelling was found to reduce planning time and, in some cases, change the surgical plan.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 414 - 414
1 Jul 2010
Patel NK Bucknill A Denning J Ahearne D Desai K Watson M
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Purpose: To determine if early MRI diagnosis in the acutely injured knee affects management, use of resources and patient satisfaction compared to conventional management with physiotherapy.

Methods: Patients referred to fracture clinic with acute knee injury in whom a specific clinical diagnosis could not be made were randomised to one of two groups. The MRI group had a scan within 2 weeks and were then reassessed in clinic with management according to the results. The control group received physiotherapy and then reassessed. Patients were assessed in clinic on presentation, at 2 weeks and then by a telephone questionnaire at 3 months. Electronic medical records were also reviewed.

Results: 48 patients were recruited in total: 23 in the MRI group (78.2% male, 21.8% female) and 25 in the control group (68% male, 32% female). The mean age was similar in the two groups (29 years (range 18–61) vs. 30 years (18–50)). The MRI group had significantly less physiotherapy appointments (5 ± 3.42 vs. 2.52 ±1.93, p=0.003) on average until definitive treatment but not outpatient appointments (2.72 ± 1.1 vs. 2.43 ±0.66, p=0.27). Median time to surgery was less in the MRI group (138 (31–199) vs.180 days (33–826) vs.) but not statistically significant (p=0.19). A similar number of patients returned to work in both groups (82.6% vs. 76%) but the MRI group had less time off work (15.82 ±22.26 vs. 20.56 ±25.38 days, p=0.48) and statistically better satisfaction scores (2 ±2.68 vs. 3.5 ±2.75, p=0.048) than the control group.

Conclusion: We have shown that early MRI in acute knee injury can provide early diagnosis of internal derangement and therefore allow targeted treatment. These patients had significantly less physiotherapy appointments and less time off work which may offset the cost of the MRI. Moreover these patients were significantly more satisfied with the service.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 141 - 141
1 Jul 2002
Bucknill A Coward K Plumpton C Tate S Bountra C Birch R Hughes S Anand P
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Study Design: To examine the innervation of the lumbar spine from patients with lower back pain, and spinal nerve roots from patients with traumatic brachial plexus injuries.

Objectives: To demonstrate the presence of nerve fibres in lumbar spine structures and spinal nerve roots, and determine whether they express the sensory neuronespecific sodium channels SNS/PN3 and NaN/SNS2.

Summary of background data: The anatomical and molecular basis of low back pain and sciatica is poorly understood. Previous studies have demonstrated sensory nerves in facet joint capsule and prolapsed intervertebral disc, but not in ligamentum flavum. The voltagegated sodium channels SNS/PN3 and NaN/SNS2 are expressed by sensory neurones which mediate pain, but their presence in the lumbar spine is unknown.

Methods: Tissue samples (ligamentum flavum n=32; facet joint capsule n=20; intervertebral disc n=15; spinal roots n=8) were immunostained with specific antibodies to protein gene product (PGP) 9.5, a pan-neuronal marker, SNS/PN3 and NaN/SNS2.

Results: PGP 9.5-immunoreactive nerve fibres were detected in 72% of ligamentum flavum and 70% of facet joint capsule but only 20% of intervertebral disc specimens. SNS/PN3-and NaN/SNS2-positive fibres were detected in 28% and 3% of ligamentum flavum and 25% and 15% of facet joint capsule specimens respectively. Numerous SNS/PN3 and NaN/SNS2-positive fibres were found in the acutely injured spinal roots, and some were still present in dorsal roots in the chronic state.

Conclusions: SNS/PN3 and NaN/SNS2-immunoreactivity is present in a subset of nerve fibres in lumbar spine structures, including ligamentum flavum and injured spinal roots. This is the first time that sensory nerve fibres have been demonstrated in the ligamentum flavum, and this raises the possibility that, contrary to the conclusions of previous studies, this unique ligament may be capable of nociception. Selective SNS/PN3 and NaN/ SNS2 blocking agents may provide new effective therapy for back pain and sciatica, with fewer side effects. Other novel ion channels are being studied in these tissues.