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Bone & Joint Open
Vol. 4, Issue 3 | Pages 210 - 218
28 Mar 2023
Searle HKC Rahman A Desai AP Mellon SJ Murray DW

Aims

To assess the incidence of radiological lateral osteoarthritis (OA) at 15 years after medial unicompartmental knee arthroplasty (UKA) and assess the relationship of lateral OA with symptoms and patient characteristics.

Methods

Cemented Phase 3 medial Oxford UKA implanted by two surgeons since 1998 for the recommended indications were prospectively followed. A 15-year cumulative revision rate for lateral OA of 5% for this series was previously reported. A total of 163 unrevised knees with 15-year (SD 1) anterior-posterior knee radiographs were studied. Lateral joint space width (JSWL) was measured and severity of lateral OA was classified as: nil/mild, moderate, and severe. Preoperative and 15-year Oxford Knee Scores (OKS) and American Knee Society Scores were determined. The effect of age, sex, BMI, and intraoperative findings was analyzed. Statistical analysis included one-way analysis of variance and Kruskal-Wallis H test, with significance set at 5%.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_16 | Pages 20 - 20
1 Dec 2021
Yang I Gammell JD Murray DW Mellon SJ
Full Access

Abstract

Background

The Oxford Domed Lateral (ODL) Unicompartmental Knee Replacement (UKR) has some advantages over other lateral UKRs, but the mobile bearing dislocation rate is high (1–6%). Medial dislocations, with the bearing lodged on the tibial component wall, are most common. Anterior/posterior dislocations are rare. For a dislocation to occur distraction of the joint is required. We have developed and validated a dislocation analysis tool based on a computer model of the ODL with a robotics path-planning algorithm to determine the Vertical Distraction required for a Dislocation (VDD), which is inversely related to the risk of dislocation.

Objectives

To modify the ODL design so the risk of medial dislocation decreases to that of an anterior/posterior dislocation.


Bone & Joint Research
Vol. 8, Issue 11 | Pages 535 - 543
1 Nov 2019
Mohammad HR Campi S Kennedy JA Judge A Murray DW Mellon SJ

Objectives

The aim of this study was to determine the polyethylene wear rate of Phase 3 Oxford Unicompartmental Knee Replacement bearings and to investigate the effects of resin type and manufacturing process.

Methods

A total of 63 patients with at least ten years’ follow-up with three bearing types (1900 resin machined, 1050 resin machined, and 1050 resin moulded) were recruited. Patients underwent full weight-bearing model-based radiostereometric analysis to determine the bearing thickness. The linear wear rate was estimated from the change in thickness divided by the duration of implantation.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 1 - 1
1 Oct 2018
Murray DW Mohammad H Matharu G Mellon SJ Judge A
Full Access

Introduction

Unicompartmental knee arthroplasty (UKA) offers significant advantages over total knee arthroplasty (TKA) but is reported to have higher revision rates in joint registries. In both the New Zealand and the UK national registry the revision rate of cementless UKR is less than cementless. It is not clear whether this is because the cementless is better or because more experienced surgeons, who tend to get better results are using cementless. We aim to use registry data to compare cemented and cementless UKA outcomes, matching for surgical experience and other factors.

Methods

We performed a retrospective observational study using National Joint Registry (NJR) data on 10,836 propensity matched Oxford UKAs (5418 cemented and 5418 cementless) between 2004 and 2015. Logistic regression was utilized to calculate propensity scores to match the cemented and cementless groups for multiple confounders using a one to one ratio. Standardised mean differences were used before and after matching to assess for any covariate imbalances. The outcomes studied were implant survival, reasons for revision and patient survival. The endpoint for implant survival was revision surgery (any component removal or exchange). Cumulative patient and implant survival rates were determined using the Kaplan-Meier method. Patients not undergoing revision or death were censored on the study end date. The study endpoints implant and patient survival were compared between cemented and cementless groups using Cox regression models with a robust variance estimator.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 2 - 2
1 Oct 2018
Dodd CAF Kennedy J Palan J Mellon SJ Pandit H Murray DW
Full Access

Introduction

The revision rate of unicompartmental knee replacement (UKR) in national joint registries is much higher than that of total knee replacements and that of UKR in cohort studies from multiple high-volume centres. The reasons for this are unclear but may be due to incorrect patient selection, inadequate surgical technique, and inappropriate indications for revision. Meniscal bearing UKR has well defined evidence based indications based on preoperative radiographs, the surgical technique can be assessed from post-operative radiographs and the reason for revision from pre-revision radiographs. However, for an accurate assessment aligned radiographs are required. The aim of the study was to determine why the revision rate of UKR in registries is so high by undertaking a radiographic review of revised UKR identified by the United Kingdom's (UK) National Joint Registry (NJR).

Methods

A novel cross-sectional study was designed. Revised medial meniscal bearing UKR with primary operation registered with the NJR between 2006 and 2010 were identified. Participating centres from all over the country provided blinded pre-operative, post-operative, and pre-revision radiographs. Two observers reviewed the radiographs.


Bone & Joint Research
Vol. 7, Issue 3 | Pages 226 - 231
1 Mar 2018
Campi S Mellon SJ Ridley D Foulke B Dodd CAF Pandit HG Murray DW

Objectives

The primary stability of the cementless Oxford Unicompartmental Knee Replacement (OUKR) relies on interference fit (or press fit). Insufficient interference may cause implant loosening, whilst excessive interference could cause bone damage and fracture.

The aim of this study was to identify the optimal interference fit by measuring the force required to seat the tibial component of the cementless OUKR (push-in force) and the force required to remove the component (pull-out force).

Materials and Methods

Six cementless OUKR tibial components were implanted in 12 new slots prepared on blocks of solid polyurethane foam (20 pounds per cubic foot (PCF), Sawbones, Malmo, Sweden) with a range of interference of 0.1 mm to 1.9 mm using a Dartec materials testing machine HC10 (Zwick Ltd, Herefordshire, United Kingdom) . The experiment was repeated with cellular polyurethane foam (15 PCF), which is a more porous analogue for trabecular bone.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVIII | Pages 55 - 55
1 May 2012
Mellon SJ Kwon Y Simpson DJ Murray DW Gill HS
Full Access

Introduction

Metal-on-metal (MoM) hip resurfacing arthroplasty is a popular choice for young and active patients. However, there are concerns recently regarding soft tissue masses or pseudotumours. The appearance of these complications is thought to be related blood metal ion levels. The level of metal ions in blood is thought to be the result of MoM wear. In the present study the contribution of acetabulum orientation to stress distribution was investigated.

Methods

Four subjects with MoM resurfacings and with known blood metal ion levels underwent motion analysis followed by CT scans. The positions of the acetabular (cup) and femoral components were determined the CT data relative to local coordinate systems in the pelvis (PCS) and the femur (FCS). Transformations, calculated from the motion analysis data, between the PCS and FCS gave the position of the cup relative to the femoral component for each frame of captured motion data.

Hip reaction forces were taken from published data1. The intersection of hip reaction force with each subject's cup and the increase in inclination required to move the force to the edge of the cup was calculated for 2% intervals during the stance phase of gait. Finite element models representing each subject's cup and femoral components were created and contact stresses were determined for the native cup inclination angle. For each model, the effect of increasing the inclination of the cup, by up to 10°, in 1° increments, was determined.


Bone & Joint Research
Vol. 1, Issue 4 | Pages 42 - 49
1 Apr 2012
Kwon Y Mellon SJ Monk P Murray DW Gill HS

Objectives

Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities.

Methods

The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans.