Dual mobility cups (DMC) reduce the risk of dislocation in femoral neck fractures (FNF). Direct anterior approach (DAA), historically promoted for better stability, has been developed in recent years for better functional results. The aim of this study was to compare the early functional results of DMC in FNF by DAA versus posterolateral approach (PLA).

A prospective study was conducted on a continuous series of patients who received DMC for FNF by DAA or PLA. The primary endpoint was Harris Hip Score and Parker score assessed at the first follow-up visit. Intraoperative complications were collected during hospitalization. One year clinical results and all cause revision rate were also collected. Radiographic data of cup positioning and limb length were evaluated.

Fifty-two patients were included in the DAA group and 54 in the PLA group. Two patients were lost to follow-up. The mean age was 72.8 years. There was no significant difference in HHS or Parker score at 3 and 12 months follow up (p=0.6, p= 0.75). DAA was associated with more intraoperative complications with 4 fractures and 1 femoral nerve deficit (p=0.018). There were 3 revisions in the DAA group (1 infection, 1 dislocation, 1 peri prosthetic fracture) and 1 in the PLA group (infection), which was not statistically significant (p=0.34). Cup anteversion was 6° greater and inclination 9° lesser in DAA group (p=0.028, p<0.01).

Results suggest that DAA does not provide any early functional benefit in THA-DMC for FNF compared to PLA. It could lead to more intraoperative complications and a higher revision rate. DAA requires an experienced surgeon and careful patient selection.

Aims

Two-stage exchange revision total hip arthroplasty (THA) performed in case of periprosthetic joint infection (PJI) has been considered for many years as being the gold standard for the treatment of chronic infection. However, over the past decade, there have been concerns about its safety and its effectiveness. The purposes of our study were to investigate our practice, collecting the overall spacer complications, and then to analyze their risk factors.

Two-stage exchange revision total hip arthroplasty performed in case of infection has been considered during many years the gold standard for treatment of chronic infection. Nevertheless, during the last decade, concerns have risen regarding its safety and its efficiency. The purpose of our study was to, first investigate the spacer complications, then to analyze their risks factors.

We retrospectively included 125 patients with chronic hip periprosthetic joint infection who underwent a two stage exchange revision arthroplasty performed between January 2013 and December 2019. All spacer complications were systematically collected and risk factors were analyzed. Statistical evaluation were performed using the Student and Mann-Whitney tests.

Our study confirms the hypothesis of a high-risk strategy with 42% of patients who had a mechanical spacer failure and a 20% recurrence of infection during the average two years period of follow-up. We found a high rate of spacer migration (23%) and a low rate of spacer fracture (8%) compared to literature.

The most important finding was that the majority of spacer complications and failures were found in a population with high medical comorbidities as highlighted by the ASA, Charlson and Lee score associations, as well as with the cardiac, pulmonary, kidney or hepatic chronic conditions.

This study showed that a two-stage hip exchange revision is a high-risk procedure regarding complications and mechanical failures of PMMA spacers.

In patients with high medical comorbidities, other strategies may be considered and interdisciplinary cooperation with other facilities are needed to identify and control each risk factor.

Introduction

Numerous fluoroscopic studies have been conducted to investigate kinematic variabilities of total knee arthroplasty (TKA). In those studies, subjects having a posterior stabilized (PS) TKA experience greater weightbearing knee flexion and posterior femoral rollback of the lateral condyle. In those same studies, subjects did experience a high incidence of variable medial condyle motion and reverse axial rotation, especially occurring when the cam engaged the post. More recently, a PS TKA was designed to accommodate both gender and ethnicity. Therefore, the objective of this study was to assess in vivo kinematics for subjects having this TKA type to determine if subjects having this PS TKA experienced more optimal knee kinematics.

Introduction

Periprosthetic joint infection (PJI) remains the main cause of failure in primary and revision total knee arthroplasties (TKAs). Local delivery of antibiotics, mainly antibiotic-loaded bone cement (ALBC), is commonly employed to prevent PJI. Over the past decade, tantalum and porous titanium have been successfully utilized as metaphyseal fixation devices to address bone loss and improve biologic fixation during revision TKA. However, no study has examined the antimicrobial properties compared to bone cement. The purpose of this study was to compare the ability of tantalum, 3D porous titanium, antibiotic-loaded bone cement (ALBC) and smooth titanium alloy (STA) to inhibit Staphylococci bacterial agents in an in vitro medium environment, based on the evaluation of the zone of inhibition (ZOI) and the antibacterial activity duration. Our study hypothesis was that we will found no significant difference between groups to inhibit Methicillin-Sensitive or Methicillin-Resistant Staphylococcus aureus (MSSA/MRSA) agents.

The contralateral femur is frequently used for preoperative templating of total hip arthroplasty assuming femoral symmetry. We aimed to define the degree of asymmetry between left and right proximal femurs and whether if affected by demographics parameters.

A CT-scan based modeling and analytics system of 346 CT-scans was used for this study, including pelvis and bilateral femora from 211 men and 135 women (mean age 61 ±16 years, mean BMI 26± 5 kg/m²⁾. The femoral neck shaft angle (NSA), femoral offset (FO), femoral neck version (FNV), femoral length (FL), canal flare index (CFI) and femoral head diameter (FHD) were calculated for each patient. We then, analyzed symmetry based on absolute differences(AD) and percentage of asymmetry(%AS).

An asymmetry >2% was found for NSA (mean AD=2.9°; mean %AS=2.3; p=0.03), FO (AD=3.8mm; %AS=9.1; p=0.01), FNV (AD=5.1°; %AS=46.7; p=0.001) and CFI (AD=0.2mm; %AS=5.4; p=0.7). Percentage of asymmetry was <2% for FL (AD=3.6mm; %AS=0.8; p=0.7) and FHD (AD=0.3mm; %AS=1.2; p=0.8). No correlation and predictive value was found between either AD or %AS and age, ethnicity, gender, height, weight or BMI.

Our data support assumptions of substantial asymmetry of the proximal femur which is not affected by demographics or proximal femoral size.

Clinical relevance: Upper femurs are not symmetric. Preoperative planning on contralateral femur might be affected this geometrical bias.

Background

A principle of Total Knee Arthroplasty (TKA) is to achieve a neutral standing coronal alignment of the limb (Hip Knee Ankle (HKA) angle) to reduce risks of implant loosening, reduce polyethylene wear, and optimise patella tracking. Several long-term studies have questioned this because the relationship between alignment and implant survivorship is weaker than previously reported. We hypothesize standing HKA poorly predicts implant failure because it does not predict dynamic HKA, dynamic adduction moment, and loading of the knee during gait. Therefore, the aim of our study is to assess the relationship between the standing (or static) and the dynamic (gait activity) HKAs.

A principle of Total Knee Arthroplasty (TKA) is to achieve a neutral standing coronal alignment of the limb (Hip Knee Ankle (HKA) angle) to reduce risks of implant loosening, reduce polyethylene wear, and optimise patella tracking. Several long-term studies have questioned this because the relationship between alignment and implant survivorship is weaker than previously reported. We hypothesize standing HKA poorly predicts implant failure because it does not predict dynamic HKA, dynamic adduction moment, and loading of the knee during gait. Therefore, the aim of our study is to assess the relationship between the standing (or static) and the dynamic (gait activity) HKAs.

We performed a prospective study on a cohort of 35 patients (35 knees) who were treated with a posterior-stabilized TKA for primary osteoarthritis between November 2012 and January 2013. Three months after surgery each patient had a standardized digital full-leg coronal radiographs and was classified as neutrally aligned TKA (17 patients), varus aligned (9 patients), and valgus aligned (4 patients). Patients then performed a gait analysis for level walking and dynamic HKA and adduction moment during the stance phase of gait were measured.

We found standing HKA having a moderate correlation with the peak dynamic varus (r=0.318, p=0.001) and the mean and peak adduction moments (r=0.31 and r=-0.352 respectively). In contrast we did not find a significant correlation between standing HKA and the mean dynamic coronal alignment (r=0.14, p=0.449). No significant differences were found for dynamic frontal parameters (dynamic HKA and adduction moment) between patients defined as neutrally aligned or varus aligned.

In our practice, the standing HKA after TKA was of little value to predict dynamic behaviour of the limb during gait. These results may explain why standing coronal alignment after TKA may have limited influence on long term implant fixation and wear.

Treatment of osteoarthritis of the knee remains a challenging problem since the evolution of the disease may be different in each compartment of the knee, as well as the state of the ligaments. Total knee arthroplasty may provide a reliable long-lasting option but do not preserve the bone stock. In another hand, compartmental arthroplasty is a bone and ligament sparing solution to manage limited osteoarthritis of the knee affecting the medial, lateral or the patello-femoral compartment.1, 2, 3

Patient's selection and surgical indication are based on the physical examination and on the radiological analysis including full-length x-rays and stress x-rays. Clinical experience has shown the need for high flexion in patients who have both high flexibility and a desire to perform deep flexion.

Additionally the shape differences related to anatomy or the patient expectations after the surgery may also affect the surgeon decision. 4

The limited incision into the extensor mechanism allows a quicker recovery which represents a functional improvement for the patient additionally to the cosmetic result. A dedicated physiotherapy starting on the following day allowing weight bearing exercises protected by crutches and focusing on early mobilization and range of motion combined to a multimodal pain management approach is critical despite the type of individualized solution chosen for the patient knee. 5

Since bony landmarks may be different form a patient to another one as well as anatomical shapes, several tools have been developed in order to provide the surgeons an assisted tool during the surgery adapted to each knee, this include navigation, patient specific instrumentation and robotic surgery.

Improving the adaptation between the implant and the patient bone during total hip arthroplasty (THA) may improve the survival of the implant. This requires a perfect understanding of the tridimensional characteristics of the patient hip. The perfect evaluation of the tridimensional anatomy of the patient hip can be done pre-operatively using X-rays and CT-scan. All patients underwent a standard x-rays evaluation in the same center according to the same protocol. Pre-operatively, the frontal analysis of the hip geometry was performed and the optimal center of rotation, CCD angle, neck length and lever arm was analyzed to choose the optimal solution for proper balance of the hip in order to obtain adequate range of motion, appropriate leg length, and correct tension of the abductors muscles. Standard or lateralized monoblock stems can be valid or modular neck shape can be choosen among 9 available shape. These 9 frontal shapes are available in standard, anteverted or retroverted shapes, leading to 27 potential neck combinations. In case of important hip deformation, a custom implant can be used in order to balance the extra-medullar geometry without compromising the intra-medullary adaptation of the stem.

We prospectively included 209 hips treated in our institution with total hip arthroplasty performed using a supine Watson-Jones approach and the same anatomic stem. The mean patient age was 68 years and the mean BMI 26 Kg/m². Intra-operatively the sagittal anatomy of the hip was analyzed and standard, ante or retro modular necks were tested for the frontal shape defined pre-operatively.

According to the pre-operative frontal planning, non-standard necks were required in 24 % of the cases to restore the anatomy of the hip. Intra-operatively, a sagittal correction using anteverted neck was required in 5% of the cases and retroverted necks in 18% of the cases. Harris hip score improved from 56 to 95 points at min. 5 year follow-up. No leg length discrepancy greater than 1 cm was observed. Restoration of the lever arm (mean 39.3 mm, range 30 to 49 mm) and of the neck length (55.2, range 43 to 68 mm) was adapted for 95% compared to the non operate opposite side. Disturbed anatomy like in DDH or post-traumatic cases may require additional solutions to balance the hip such combined osteotomy or customized stem and neck.

Partial knee arthroplasty (PKA), either medial or lateral unicompartmental knee artroplasty (UKA) or patellofemoral arthroplasty (PFA) are a good option in suitable patients and have the advantages of reduced operative trauma, preservation of both cruciate ligaments and bone stock, and restoration of normal kinematics within the knee joint. However, questions remain concerning long-term survival. The goal of this review article was to present the long-term results of medial and lateral UKA, PFA and combined compartmental arthroplasty for multicompartmental disease. Medium- and long-term studies suggest reasonable outcomes at ten years with survival greater than 95% in UKA performed for medial osteoarthritis or osteonecrosis, and similarly for lateral UKA, particularly when fixed-bearing implants are used. Disappointing long-term outcomes have been observed with the first generation of patellofemoral implants, as well as early Bi-Uni (ie, combined medial and lateral UKA) or Bicompartmental (combined UKA and PFA) implants due to design and fixation issues. Promising short- and med-term results with the newer generations of PFAs and bicompartmental arthroplasties will require long-term confirmation.

Cite this article: Bone Joint J 2015;97-B(10 Suppl A):9–15.

Introduction:

Recent studies have concluded that gender influences hip morphology at the time of surgery as well as dysplastic development of the hip. This may lead to a particular choice of implant including stem design and/or neck modularity. In this study we hypothesized that not only gender but also morphotype and etiology (primary osteoarthritis versus aseptic osteonecrosis) may be a significant factor to predict the anatomy of the hip at the time of total hip arthroplasty (THA).

Introduction

Previous fluoroscopic studies compared total knee arthroplasty (TKA) kinematics to normal knees. It was our hypothesis that comparing TKA directly to its non-replaced controlateral knee may provide more realistic kinematics information. Using fluoroscopic analysis, we aimed to compare knee flexion angles, femoral roll-back, patellar tracking and internal and external rotation of the tibia.

Anterior knee pain is one of the most frequently reported musculoskeletal complaints in all age groups. However, patient's complaints are often nonspecific, leading to difficulty in properly diagnosing the condition. One of the causes of pain is the degeneration of the articular cartilage. As the cartilage deteriorates, its ability to distribute the joint reaction forces decreases and the stresses may exceed the pain threshold. Unfortunately, the assessment of the cartilage condition is often limited to a detailed interview with the patient, careful physical examination and x-ray imaging. The X-ray screening may reveal bone degeneration, but does not carry sufficient information of the soft tissues' conditions. More advanced imaging tools such as MRI or CT are available, but these are expensive, time consuming and are only suitable for detection of advanced arthritis. Arthroscopic surgery is often the only reliable option, however due to its semi-invasive nature, it cannot be considered as a practical diagnostic tool. However, as the articular cartilage degenerates, the surfaces become rougher, they produce higher vibrations than smooth surfaces due to higher friction during the interaction. Therefore, it was proposed to detect vibrations non-invasively using accelerometers, and evaluate the signals for their potential diagnostic applications.

Vibration data was collected for 75 subjects; 23 healthy and 52 subjects suffering from knee arthritis. The study was approved by the IRB and an Informed Consent was obtained prior to data collection. Five accelerometers were attached to skin around the knee joint (at the patella, medial and lateral femoral condyles, tibial tuberosity and medial tibial plateau). Each subject performed 5 activities; (1) flexion-extension, (2) deep knee bend, (3) chair rising, (4) stair climbing and (5) stair descent. The vibration and motion components of the signals were separated by a high pass filter. Next, 33 parameters of the signals were calculated and evaluated for their discrimination effectiveness (Figure 1). Finally the pattern recognition method based on Baysian classification theorem was used for classify each signal to either healthy or arthritic group, assuming equal prior probabilities.

The variance and mean of the vibration signals were significantly higher in the arthritic group (p=2.8e-7 and p=3.7e-14, respectively), which confirms the general hypothesis that the vibration magnitudes increase as the cartilage degenerates. Other signal features providing good discrimination included the 99^th quantile, the integral of the vibration signal envelope, and the product of the signal envelope and the activity duration. The pattern classification yielded excellent results with the success rate of up to 92.2% using only 2 features, up to 94.8% using 3 (Figure 2), and 96.1% using 4 features.

The current study proved that the vibrations can be studied non-invasively using a low-cost technology. The results confirmed the hypothesis that the degeneration of the cartilage increases the vibration of the articulating bones. The classification rate obtained in the study is very encouraging, providing over 96% accuracy. The presented technology has certainly a potential of being used as an additional screening methodology enhancing the assessment of the articular cartilage condition.

Background

Acetabular component malpositioning during hip arthroplasty increases the risk of dislocation, reduces range of motion and can be responsible for early wear and loosening. There have been numerous reports on the optimal orientation of the acetabular component in total hip arthroplasty (THA). Lewinnek et al recommended an abduction angle of 40°±10° and an anteversion of 15°±10° for cup alignment in THA. The purpose of the in vivo study was to compare computer assisted acetabular component insertion versus free-hand placement. The goal of the cadaveric study was to compare in vitro a new tool using ultrasound with the standard percutaneous manual methods for the anterior pelvic plane registration during computer-assisted total hip arthroplasty.

Introduction

It is documented in the literature the very good results of lateral unicompartmental knee arthroplasty (UKA) when the standard accepted indications are followed. In our experience these indications can be extended to include post-traumatic osteoarthritis (OA) with malunion secondary to tibial plateau fracture. We report our results concerning 15 UKAs in these particular situations.

Purpose of the study: Three-screw fixation is the classical treatment for true Garden I in the elderly patient. Complication rates have been high in the literature. Furthermore, in this context outcome for arthroplasty after failed osteosynthesis is less satisfactory than first-intention arthroplasty. This is why functional treatment of Garden I fractures of the neck of the femur has been proposed, including rapid return to the upright position and strict radiographic and clinical control. The purpose of this work was to first evaluate the results of this management option for true Garden I fractures in patients aged over 65 years and second to search for factors predictive of secondary displacement.

Material and methods: All patients aged over 65 years and admitted to the unit for true Garden I fractures from January 2005 to December 2006 were included in this prospective study. A functional treatment including early return to the upright position and walking test on day 1 was instituted, followed by radiographic controls on days 2, 7, 14, 21, and 45 then at 3 months and one year. Referral to a rehabilitation centre at discharge on day 5 was scheduled if there was no displacement. In the event of a displacement, arthroplasty was performed. Fifty-seven patients, mean age 82.8±8.5 years (range 65–99) were included. The radiographic and clinical follow-ups were made by an independent observer.

Results: The displacement rate was 29.8%. These patients were treated by arthroplasty. In the group of patients without displacement, at minimum one year follow-up, there has been no need for surgical revision excepting one case of osteonecrosis at one year requiring implantation of a total prosthesis. The mean Parker score in this group was 6.4 and the mean Harris score 83, it was 85 in the arthroplasty group. Among the predictive factors identified at multivariate analysis were: age, gender, side, type of fracture, fracture orientation, degree of valgus or sagittal displacement, general status. Displacement was not statistically predictive.

Discussion: The results of our prospective study show that 70% of patients included were treated successfully without surgery, confirming reports in the literature and justifying utilisation of this management strategy.

Purpose of the study: It has been demonstrated that the anatomy of the distal femur differs by gender. The ratio of the mediolateral/anteroposterior distance, the shape of the distal femur, and the orientation of the trochlea differ between males and females. To adapt to these differences, prostheses specifically designed for female patients (TKAgender) were developed. The purpose of our study was to compare the first objective and subjective outcomes with these prostheses.

Material and methods: Thirty women who underwent bilateral surgery within a six month interval for degenerative joint disease of the knee between March 2006 and March 2008 were included in a comparative prospective study. The side receiving the gender implant was determined at random. Operative and postoperative protocols were the same excepting the femoral implant. Patients were not informed of which knee had received the gender prosthesis. Mean age in this series was 67 years and mean BMI 26. All implants were cemented. At minimum one year follow-up, objective and subjective analysis included specific questions concerning preference and quality of life presented by an independent observer.

Results: The Knee Society clinical scores were comparable in the two groups, as were the results for the different items of the KOOS score. For preferences: the patients preferred the gender knee in 75% of the cases (p< 0.01), they reported less noise or cracking sounds in the anterior part of the knee for 68% (p=0.03) and had the impression that the knee recovered faster in 64% (p=0.04).

Discussion: To our knowledge, this is the first report of results concerning implants specifically designed for female patients. At short-term, the only difference in the patients’ preference was a subjective feeling of less impairment for the patellar track. It will be interesting to follow these patients to assess the long-term impact on the patellofemoral articulation.

Most of computer-assisted computer assisted system rely on the peri-operative acquisition of the anterior pelvic plane defined as the plane crossing the two anterior iliac spine and the symphysis. The goal of this study was to evaluate in vivo and in vitro the accuracy of the anterior pelvic plane acquisition, considered as the reference for computer-assisted total hip arthroplasty (THA).

Cup placement was performed using an imageless computer-assisted system in thirty patients during THA. Post-operatively the position of the cup was evaluated on computed tomography using a validated tridimensional software. The differences between the perioperative and postoperative angles for abduction and anteversion were compared using a two-group pair test.

On two cadavers four clinicians performed ten times the anterior pelvic plane acquisition using three Methods: percutaneously, with ultrasound and by direct bony acquisition defined as the reference. The mean error for each anterior pelvic plane acquisition method was compared using a univariate variance model for repeated measurements.

In vivo, the mean difference between the perioperative and postoperative abduction angles was 4° and not statistically significant. For anteversion, the difference was 4° and not significant in patients with BMI < 27. The difference was 11° and significant in patients with BMI > 27 (p< 0.001). In vitro, the mean errors for rotation and tilt were respectively 3.8 ° and 19.25 ° for cutaneous acquisition, 2.8° and 6.2° for ultrasound acquisition method. The errors were statistically higher with the percutaneous method (p< 0.001).

According to our results, the accuracy of the standard percutaneous acquisition method of the anterior pelvic plane in computer-assisted THA is limited. The ultrasound acquisition method may represent a reliable alternative.

Purpose of the study: Besides enabling a precise calculation of the needs for blood (in ml) for each type of orthopaedic surgery, an adequate estimation of average total blood loss (TBL) as a function of total blood volume (TBV) enables initiation of blood sparing techniques. Thus, when the balance is negative, erythropoietin could be advisable. The purpose of this work was to analyse the impact of prescribing erythropoietin as a function of the expected blood balance on the rate of homologous blood transfusions. We also wanted to determine the financial impact of this prescription strategy.

Material and methods: This prospective study included 229 patients (153 THA and 76 TKA) who underwent surgery from January 2005 to December 2008 with a standard anaesthesia, analgesia and surgical protocol. TBL was considered to be 10% of TBV for THA and TKA. Mean gain in serum haemoglobin (Hb) per injection of erythropoietin (1 ampoule Eprex) was 0.8 g/dl. Using the patient’s Hb level at the preop exam (Hbpreop), the anaesthetist determined the volume available (VA) for each patient and for each type of operation. When VA was negative, the Hb needed to reach the desired level (HbA) so that VA=0 (zero risk of transfusion) was calculated. The number of Eprex ampoules prescribed (amp) was determined from the formula: (HbA-Hbpreop)/0.8. Hb levels on day 0, day 1, day 3(discharge) and day 28 were noted, as were the number of homologous transfusions and the total number of ampoules of Eprex delivered.

Results: Sixty-six patient received one amp (33.2%), 96 had two amp (42%), 40 three amp (17.5%) and 17 four amp (7.4%). For 220 patients (92%), Eprex delivered was within the approved dose (92%). The mean Hb levels were: Hbpreop=12.4, HbA=13.5, Hbd0=13.9, Hbdischarge=11.2, and Hbd28=11.9. Total consumption was 456 amp instead of 916 (229x4), i.e. a savings of 460 amp corresponding to 173 880 euros (460 x 378 euros). There were six homologous transfusions (2.6%).

Discussion: In orthopaedic surgery, adapted prescription of erythropoietin as a function of the TBL enabled, in this series, a simplification of the prescription procedure and avoided the risks related to high Hb levels > 15g with a financial savings of 760 euros per operation (173880 euros for 229 patients) without increasing the rate of homologous transfusion. This strategy is currently being evaluated for prosthesis revision surgery.