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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_6 | Pages 6 - 6
1 May 2019
Elwood R El-Hakeem O Singh Y Weiss O Khanduja V
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Background

Elite performance has tremendous physical demands and places elite athletes at an increased risk of sustaining a variety of orthopaedic injuries (1–4). Pain around the hip is common in high-level athletes representing up to 6% of all athletic injuries (5–7). Expedient diagnosis and effective treatment are paramount for their future sporting careers and to prevent subsequent joint degeneration. The purpose of this systematic review was to evaluate the outcome and the rate of return to play (RTP) following hip arthroscopy in elite athletes.

Methods

A computer-based systematic search followed the PRISMA Guidelines (8) was performed using the 6 most comprehensive databases (CENTRAL, PUBMED, EMBASE, SCOPUS, EBSCO, Google Scholar and Web of Science) and included all published studies from inception until November 1st 2018. Weighted means were calculated for the rate of RTP and duration and for patient reported outcome measures (PROMs).


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_9 | Pages 6 - 6
1 May 2018
Bartlett J Lawrence J Yan M Guevel B Stewart M Khanduja V
Full Access

Introduction

Decreases in trainees' working hours, coupled with evidence of worse outcomes when hip arthroscopies are performed by inexperienced surgeons, mandate the development of additional means of arthroscopic training. Though virtual reality simulation training has been adopted by other surgical specialities, its slow uptake in arthroscopic training is due to a lack of evidence as to its benefits. These benefits can be demonstrated through learning curves associated with simulator training – with practice reflecting measurable increases in validated performance metrics.

Materials & Methods

Twenty-five medical students completed seven simulated arthroscopies of a healthy virtual hip joint in the supine position on a simulator previously shown to have construct validity. Twelve targets had to be visualised within the central compartment; six via the anterior portal, three via the anterolateral portal and three via the posterolateral portal. Eight students proceeded to complete seven probe examinations of a healthy virtual hip joint. Eight targets were probed via the anterolateral portal. Task duration, number of collisions with soft tissue and bone, and distance travelled by arthroscope were measured by the simulator for every session.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_12 | Pages 46 - 46
1 Jun 2017
Lawrence J Khanduja V Audenaert E
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Hip arthroscopy is a rapidly expanding technique that has a steep learning curve. Simulation may have a role in helping trainees overcome this. However there is as yet no validated hip arthroscopy simulator. This study aimed to test the construct validity of a virtual reality hip arthroscopy simulator.

Nineteen orthopaedic surgeons performed a simulated arthroscopic examination of a healthy hip joint in the supine position. Surgeons were categorized as either expert (those who had performed 250 hip arthroscopies or more) or novice (those who had performed fewer than this). Twenty-one targets were visualized within joint; nine via the anterior portal, nine via the anterolateral and three via the posterolateral. This was followed by a task testing basic probe examination of the joint in which a series of eight targets were probed via the anterolateral portal. Each surgeon's performance was evaluated by the simulator using a set of pre-defined metrics including task duration, number of soft tissue & bone collisions, and distance travelled by instruments. No repeat attempts at the tasks were permitted. Construct validity was then evaluated by comparing novice and expert group performance metrics over the two tasks using the Mann–Whitney test, with a p value of less than 0.05 considered significant.

On the visualization task, the expert group outperformed the novice group on time taken (P=0.0003), number of collisions with soft tissue (P=0.001), number of collisions with bone (P=0.002) and distance travelled by the arthroscope (P=0.02). On the probe examination, the two groups differed only in the time taken to complete the task (P=0.025).

Increased experience in hip arthroscopy was reflected by significantly better performance on the VR simulator across two tasks, supporting its construct validity.

This study validates a virtual reality hip arthroscopy simulator and supports its potential for developing basic arthroscopic skills.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_12 | Pages 49 - 49
1 Jun 2017
Bartlett J Lawrence J Khanduja V
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To quantify the risk posed to the Lateral Femoral Cutaneous Nerve (LFCN) during Total Hip Arthroplasty using the Minimally Invasive Anterior Approach (MIAA), and during placement of the Anterior Portal (AP) in Supine Hip Arthroscopy (SHA).

Forty-five hemipelves from thirty-nine cadavers were dissected. The LFCN was identified proximal to the inguinal ligament (IL), and its path in the thigh identified. The positions of the nerve and its branches in relation to the MIAA incision and the site for AP placement were measured using Vernier Callipers.

44% of nerves crossed the incision line used in the MIAA, at an average distance of 47 ± 28mm from the proximal end of the incision. Of those that did not cross the incision line, the average minimum distance between the nerve and incision was 14.4 ± 7.4mm, occurring on average 74.0 ± 37.3mm from the proximal end of the incision. In addition, the AP was placed in the path of the nerve on 38% of occasions. The nerve took an oblique path, and when found not to intersect with the AP portal, was located 5.7 ± 4.5mm from the portal's edge. We found a reduction in risk if the portal is moved medially or laterally by 15mm from its current location.

The LFCN is at high risk of injury during both THA using the MIAA and SHA using the AP. Our study emphasises the need for meticulous dissection during these procedures, and thorough explanation of these risk whilst consenting patients. We suggest that relocation of the AP 15mm more laterally or medially will reduce the risk posed to the LFCN.


Bone & Joint Research
Vol. 6, Issue 3 | Pages 144 - 153
1 Mar 2017
Kharwadkar N Mayne B Lawrence JE Khanduja V

Objectives

Bisphosphonates are widely used as first-line treatment for primary and secondary prevention of fragility fractures. Whilst they have proved effective in this role, there is growing concern over their long-term use, with much evidence linking bisphosphonate-related suppression of bone remodelling to an increased risk of atypical subtrochanteric fractures of the femur (AFFs). The objective of this article is to review this evidence, while presenting the current available strategies for the management of AFFs.

Methods

We present an evaluation of current literature relating to the pathogenesis and treatment of AFFs in the context of bisphosphonate use.


Bone & Joint Research
Vol. 6, Issue 1 | Pages 66 - 72
1 Jan 2017
Mayne E Memarzadeh A Raut P Arora A Khanduja V

Objectives

The aim of this study was to systematically review the literature on measurement of muscle strength in patients with femoroacetabular impingement (FAI) and other pathologies and to suggest guidelines to standardise protocols for future research in the field.

Methods

The Cochrane and PubMed libraries were searched for any publications using the terms ‘hip’, ‘muscle’, ‘strength’, and ‘measurement’ in the ‘Title, Abstract, Keywords’ field. A further search was performed using the terms ‘femoroacetabular’ or ‘impingement’. The search was limited to recent literature only.


Bone & Joint 360
Vol. 5, Issue 6 | Pages 8 - 12
1 Dec 2016
Kumar KHS Lawrence JE Khanduja V


Bone & Joint Research
Vol. 2, Issue 12 | Pages 276 - 284
1 Dec 2013
Karlakki S Brem M Giannini S Khanduja V Stannard J Martin R

Objectives

The period of post-operative treatment before surgical wounds are completely closed remains a key window, during which one can apply new technologies that can minimise complications. One such technology is the use of negative pressure wound therapy to manage and accelerate healing of the closed incisional wound (incisional NPWT).

Methods

We undertook a literature review of this emerging indication to identify evidence within orthopaedic surgery and other surgical disciplines. Literature that supports our current understanding of the mechanisms of action was also reviewed in detail.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 87 - 87
1 Sep 2012
Mertes S Raut S Khanduja V
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Aim

The aim of this study was to determine the effects of using the Bellovac autologous blood salvage system on blood transfusion requirements, adverse event rate, post-operative length of stay (POLOS) and mobilisation in patients who have undergone a total knee replacement.

Methods

This is a retrospective cohort study of 471 patients who underwent a total knee replacement (TKR) at our institution between January 2008 and August 2009. All patients received an autologous blood salvage drain in theatre. Their medical records were reviewed and a database created to assess the efficacy of the blood salvage system.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 10 - 10
1 Mar 2012
Mertes S Raut S Khanduja V
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Aim

The aim of this study was to determine the factors which were responsible for differences between patients achieving the Trust target of discharge on post-operative day 5 after a primary total knee replacement and those not achieving it, in the cohort of over 75 year olds.

Methods and Results

Of all the patients undergoing a TKR at Addenbrooke's Hospital in 2008, those over 75 were identified (n=103). From the literature pre-, intra- and post-operative factors that had previously been shown to affect length of stay were identified. Patient notes were examined for details on each of these and the patients divided into 2 groups according to whether their discharge was achieved by day 5 or not. Data from 74 operations was available at the time of submission of this abstract. Pearson's Chi-squared test, student's independent t-test or the Mann-Whitney U test were performed on the data depending on the nature of the variable analysed. The following factors were found to be significantly different between the 2 groups at the 95% confidence level: pre-operative use of a walking aid (p=0.033), pre-operative Hb (p=0.003), post-operative Hb (p=0.001), post-operative requirement of a blood transfusion, post-operative complication (p<0.001), post-operative day on which active knee flexion to 90° was achieved (p=0.003). In addition the following factors were found to be significant at the 90% confidence level: age (p=0.082), comorbidity (p=0.086), marital status (p=0.095) and mobilisation by post-operative day 2 (p=0.082)


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 30 - 30
1 Mar 2012
Khanduja V Villar R
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Aim

The aim of this study was to assess the role of hip arthroscopy in the management of hip pain in elite athletes.

Patients and methods

It is a retrospective study of prospectively collected data. 31 hip arthroscopies were performed on 27 elite athletes. All the patients were assessed pre-operatively with a thorough clinical examination, radiographs and MRI scans. The modified HHS was also recorded for all the patients' pre and post-operatively. All operations were performed by the senior author, and the patients were assessed at 6 weeks, 3 months, 6 months and a year following the operation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 46 - 46
1 Mar 2012
H HS Suhani H Lydia Q Nair N Khanduja V
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Aim

The aim of this study was to study the course of the infra-patellar branch of the saphenous nerve (IPBSN) and describe its anatomical variations and relations.

Materials and Methods

Twenty-eight formalin-fixed cadaver lower extremity specimens were methodically dissected in the University Department of Anatomy. Dissection included identifying the saphenous nerve and tracing it distally till it pierced the deep fascia between the tendons of gracilis and sartorius. At this point, the saphenous nerve gave a branch that pierced the sartorius and became subcutaneous, known as the infrapatellar branch. The association of the nerve trunk with the sartorius muscle in terms of whether it originated above it, below it or pierced through it was studied. Following this the nerve was dissected along its course distally to the point of its termination where it gave one to three branches. The relationship of the point of termination of the IPBSN with bony surface landmarks like the medial border of the patella, the apex of the patella and the tibial tuberosity were also studied. The distance of the trunk from medial margin of patella was measured.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 156 - 156
1 Feb 2012
Khanduja V Somayaji S Utukuri M Dowd G
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Objective

The aim of this study was to assess the results of combined arthroscopically assisted posterior cruciate ligament reconstruction and open reconstruction of the posterolateral corner in patients with chronic (3 months or more) symptomatic instability and pain.

Patients & methods

A retrospective analysis of all the patients who had a combined reconstruction of the posterior cruciate ligament and the posterolateral corner between 1996 and 2003 was carried out. Nineteen patients who had the combined reconstruction were identified from the database. All the patients were assessed pre- and post-operatively by physical examination and three different ligament rating scores. All the patients also had weight bearing radiographs, MRI scans and an examination under anaesthesia and arthroscopy pre-operatively. The PCL reconstruction was performed using an arthroscopically assisted single anterolateral bundle technique and the posterolateral corner structures were reconstructed using an open Larson type of tenodesis.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 386 - 386
1 Jul 2010
Khanduja V Sisak K Villar R
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Aim: The aim of this study was to assess the role of Hip Arthroscopy in the patient with a symptomatic Resurfacing arthroplasty of the hip.

Patients and Methods: Twelve consecutive patients who presented to our clinic with a painful resurfacing and indeterminate or normal investigations underwent an arthroscopy of their resurfacing were prospectively enrolled into the study following appropriate consent. The pre-operative investigations included haematological indices and acute phase reactants to rule out infection along with plain radiographs and an isotope bone scan.

Results: (table deleted)

Conclusions: Assessment of a symptomatic resurfacing is usually difficult and becomes more challenging in the background of normal or indeterminate investigations. However, in this situation, we found that in experienced hands, hip arthroscopy can be utilised as an effective tool for aiding diagnosis and offering therapeutic interventions in these patients.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 423 - 423
1 Jul 2010
Shahin H H Suhani H Lydia Q Nair N Khanduja V
Full Access

Aim: The aim of this study was to study the course of the infra-patellar branch of the saphenous nerve (IPBSN) and describe its anatomical variations and relations.

Materials and Methods: Twenty-eight formalin-fixed cadaver lower extremity specimens were methodically dissected in the University Department of Anatomy. Dissection included identifying the saphenous nerve and tracing it distally till it pierced the deep fascia between the tendons of gracilis and sartorius. At this point, the saphenous nerve gave a branch that pierced the sartorius and became subcutaneous, known as the infrapatellar branch. The association of the nerve trunk with the sartorius muscle in terms of whether it originated above it, below it or pierced through it was studied. Following this the nerve was dissected along its course distally to the point of its termination where it gave one to three branches. The relationship of the point of termination of the IPBSN with bony surface landmarks like the medial border of the patella, the apex of the patella and the tibial tuberosity were also studied. The distance of the trunk from medial margin of patella was measured.

Conclusions: The anatomy of the IPBSN along with its branches is quite variable and a thorough knowledge of the same is essential to any knee surgeon to avoid injury to this structure.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 399 - 400
1 Sep 2009
Brust K Khanduja V Dandachli W Iranpour F Henckel J Hart AJ Cobb J
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Radiological measurements are an essential component of the assessment of outcome following knee arthroplasty. However, plain radiographic techniques can be associated with significant projectional errors because they are a two-dimensional (2D) representation of a three-dimensional (3D) structure. Angles that are considered within the target zone on one film may be outside that zone on other films. Moreover, these parameters can be subject to significant inter-observer differences when measured. The aim of our study therefore was to quantify the variability between observers evaluating plain radiographs following Unicompartmental knee arthroplasty.

Twenty-three observers, made up of Orthopaedic Consultants and trainees, were asked to measure the coronal and sagittal alignment of the tibial and femoral components from the post-operative long-leg plain radiograph of a Unicompartmental knee arthroplasty. A post-operative CT scan using the low dose Imperial knee protocol was obtained as well and analysed with 3D reconstruction software to measure the true values of these parameters. The accuracy and spread of the pain radiographic measurements were then compared with the values obtained on the CT.

On the femoral side, the mean angle in coronal alignment was 1.5° varus (Range 3.8, SD 1, min 0.1, max 3.9), whereas the mean angle in sagittal alignment was 8.6° of flexion (Range 7.5, SD 1.5, Min 3.7, Max 11.2). The true values measured with CT were 2.4° and 11.0° respectively. As for the tibial component, the mean coronal alignment angle was 89.7° (Range 11.6, SD 3.3, Min 83.8, Max 95.4), and the mean posterior slope was 2.4° (Range 8.7, SD 1.6, Min -2, Max 6.7). The CT values for these were 87.6° and 2.7° respectively.

We conclude that the plain radiographic measurements had a large scatter evidenced by the wide ranges in the values obtained by the different observers. If only the means are compared, the plain radiographic values were comparable with the true values obtained with CT (that is; accuracy was good) with differences ranging from 0.3° to 2.4°. The lack of precision can be avoided with the use of CT, particularly with the advent of low-dose scanning protocols.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 540 - 540
1 Aug 2008
Khanduja V Villar RN
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Aim: The aim of this study was to determine if a correlation exists between the impingement test and the arthroscopic findings at the acetabular rim in non-dysplastic hips. Secondarily, we also wanted to establish if there was a correlation between the pain experienced on the impingement test and the pathology identified.

Patients and Methods: Sixty-two consecutive patients who were due to have an arthroscopy of the hip in our unit were prospectively recruited into the study. All the dysplastic hips were excluded from the study. One observer was involved in examining all the patients and another one in performing all the arthroscopies. The impingement test was considered positive if at 90 degrees of flexion, adduction and internal rotation, the patient complained of discomfort or pain. If the patient experienced pain this was described as a strongly positive test and if there was discomfort experienced it was considered as a weakly positive test. The test was performed on the morning of the arthroscopy and all the intra-articular findings recorded at arthroscopy. A tear of the acetabular labrum and chondral damage in the antero-superior margin of the acetabulum were considered as positive pathology at the acetabular rim.

Results : There were 40 males and 22 females in the study group. The impingement test was positive in 57 patients, strongly positive in 42 and weakly positive in 15. The arthroscopy revealed positive pathology in terms of an acetabular labrum tear and/or chondral damage at the acetabular rim in 55 patients. A negative test was recorded in 5 patients but there was positive rim pathology in two of these 5 patients.

Conclusion: The impingement test correlates positively with the pathology at the acetabular rim; the sensitivity of the test for diagnosing acetabular rim pathology is 96.4 % and the specificity is only 60 % in non-dysplastic hips. However, we did not identify any correlation between the level of pain and the pathology observed.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 581 - 581
1 Aug 2008
Dannawi Z Khanduja V El-Zebdeh M
Full Access

Background: Arthroscopic visualisation of the postero-medial and posterolateral compartments of the knee through the intercondylar notch using the anterolateral and anteromedial portals respectively is not commonly practiced. The purpose of this study was to prospectively evaluate whether these views are useful either diagnostically, therapeutically or both in a routine knee arthroscopy.

Patients and Methods: It is a prospective study of two hundred consecutive patients who underwent a routine knee arthroscopy in our unit using the standard portals following an appropriate clinical and radiological evaluation. Posteromedial and posterolateral compartment visualisation through the intercondylar notch was undertaken in all the patients. An evaluation of the ease of the technique, the usefulness of visualisation and the morbidity associated with the procedure were recorded.

Results: The technique was deemed simple to perform in 91% of the patients. It was found to be more difficult in knees with degenerative joint disease. Posteromedial and posterolateral compartment visualisation was found to be useful for diagnosis or treatment in 15% and 6% of the diagnosed conditions respectively. The technique was most useful for tears of the posterior horn of the medial meniscus, most of which were not detected by visualisation from the anteromedial compartment alone. Visualisation of the compartments was deemed adequate in 98% of the patients. There was no morbidity associated with this procedure.

Conclusion: We believe that visualisation of the pos-teromedial and posterolateral compartment in a routine knee arthroscopy is beneficial; and an easy and safe procedure to perform.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 322 - 322
1 Jul 2008
Khanduja V Somayaji HS Utukuri M Dowd G
Full Access

Objective: The aim of this study was to assess the results of combined arthroscopically assisted posterior cruciate ligament reconstruction and open reconstruction of the posterolateral corner in patients with chronic (3 months or more) symptomatic instability and pain.

Patients & Methods: A retrospective analysis of all the patients who had a combined reconstruction of the posterior cruciate ligament and the posterolateral corner between 1996 and 2003 was carried out. Nineteen patients who had the combined reconstruction were identified from the database. All the patients were assessed pre and post-operatively by physical examination and three different ligament rating scores. All the patients also had weight bearing radiographs, MRI scans and an examination under anaesthesia and arthroscopy pre-operatively. The PCL reconstruction was performed using an arthroscopically assisted single anterolateral bundle technique and the posterolateral corner structures were reconstructed using an open Larson type of tenodesis.

Results: Pre-operatively all the patients had a grade III posterior sag and demonstrated more than 20 degrees of external rotation as compared to the opposite normal knee on the Dial test. The average follow up was 66.8 months (range 24–108). Post-operatively 7 patients had no residual posterior sag, 11 patients had a grade I posterior sag and 1 patient had a grade II posterior sag. Five of the 19 patients demonstrated minimal residual posterolateral laxity. The Lysholm score improved from a mean of 41.2 to 76.5 (P=0.0001) and the Tegner score from a mean of 2.6 to 6.4 (p=0.0001).

Conclusions: We conclude that while a combined reconstruction of chronic posterior cruciate ligament and pos-terolateral corner instability does not restore complete anatomical stability, improvement in symptoms and function demonstrate its value in these difficult injuries.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 316 - 316
1 Jul 2008
Khanduja V Ashraff S Malawa G Dolan T
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Objective: To determine whether patient information leaflets improve patient recall during the process of informed consent.

Design: Prospective randomised controlled trial which compared a group of patients who were posted a patient information leaflet with those given verbal consent only.

Setting: Orthopaedic Unit of a District General Hospital

Patients: 110 patients were selected, of which 57 were randomly allocated to receive patient information leaflets through the post and 53 were given verbal consent only.

Outcome Measure: The recall of information given to the patient. This was tested using a questionnaire on admission. Each patient was allocated a score out of ten.

Results: There was a significant difference between the group who received patient information leaflets compared to those who did not (P< 0.0001, CI 2.0 to 3.1).

Conclusion: Patient information leaflets are a useful tool for the surgeon to improve the recall of the information given to the patient, in order to facilitate informed consent.